C-Phycocyanin Extracted from Spirulina Using a Green Solvent Approach Presents an Anti-Obesity Characteristic in Mice Fed a Hyperlipidic Diet

AIN-93 Purified Diets for Laboratory Rodents: Final Report of the American Institute of Nutrition Ad Hoc Writing Committee on the Reformulation of the AIN-76A Rodent Diet

Reeves, P. G., Nielsen, F. H., & Fahey, G. C., Jr. (1993) · Journal of Nutrition · doi:10.1093/jn/123.11.1939 · Cited by 8,730 · see citing works

The hormone resistin links obesity to diabetes

Steppan, C. M., Bailey, S. T., Bhat, S., Brown, E. J., Banerjee, R. R., Wright, C. M., Patel, H. R., Ahima, R. S., & Lazar, M. A. (2001) · Nature · doi:10.1038/35053000 · Cited by 4,755 · see citing works

Adipokines: inflammation and the pleiotropic role of white adipose tissue

Trayhurn, P., & Wood, I. S. (2004) · British Journal of Nutrition · doi:10.1079/bjn20041213 · Cited by 2,210 · see citing works

Physiological role of adipose tissue: white adipose tissue as an endocrine and secretory organ

Trayhurn, P., & Beattie, J. H. (2001) · Proceedings of The Nutrition Society · doi:10.1079/pns200194 · Cited by 1,259 · see citing works

Making sense of the "clean label" trends: A review of consumer food choice behavior and discussion of industry implications.

Asioli, D., Aschemann-Witzel, J., Caputo, V., Vecchio, R., Annunziata, A., Næs, T., & Varela, P. (2017) · Food Research International · doi:10.1016/j.foodres.2017.07.022 · Cited by 997 · see citing works

The noncanonical NF‐κB pathway

Sun, S. (2012) · Immunological Reviews · doi:10.1111/j.1600-065x.2011.01088.x · Cited by 724 · see citing works

Production of phycocyanin—a pigment with applications in biology, biotechnology, foods and medicine

Eriksen, N. T. (2008) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-008-1542-y · Cited by 714 · see citing works

The molecular inflammatory process in aging

Chung, H. Y., Sung, B., Jung, K. J., Zou, Y., & Yu, B. P. (2006) · Antioxidants & Redox Signaling · doi:10.1089/ars.2006.8.572 · Cited by 437 · see citing works

High fat diet induced obesity model using four strains of mice: Kunming, C57BL/6, BALB/c and ICR

Li, J., Wu, H., Liu, Y., & Yang, L. (2020) · EXPERIMENTAL ANIMALS · doi:10.1538/expanim.19-0148 · Cited by 268 · see citing works

Pathways to obesity

Jéquier, E. (2002) · International Journal of Obesity · doi:10.1038/sj.ijo.0802123 · Cited by 250 · see citing works

High fat induces acute and chronic inflammation in the hypothalamus: effect of high-fat diet, palmitate and TNF-α on appetite-regulating NPY neurons

Dalvi, P. S., Chalmers, J. A., Luo, V., Han, D.-Y., Wellhauser, L., Liu, Y., Tran, D. Q., Castel, J., Luquet, S. H., Wheeler, M. B., et al. (2016) · International Journal of Obesity · doi:10.1038/ijo.2016.183 · Cited by 223 · see citing works

Change of cytokine balance in diet-induced obese mice

Mito, N., Hosoda, T., Kato, C., et al. (2000) · Metabolism · doi:10.1053/meta.2000.9523 · Cited by 113 · see citing works

High‐Fat Diet Induces Leptin Resistance in Leptin‐Deficient Mice

Koch, C. E., Lowe, C., Pretz, D., Steger, J., Williams, L. M., & Tups, A. (2014) · Journal of Neuroendocrinology · doi:10.1111/jne.12131 · Cited by 111 · see citing works

Antioxidant Potential of Nature’s “Something Blue”: Something New in the Marriage of Biological Activity and Extraction Methods Applied to C-Phycocyanin

Fratelli, C., Burck, M., Amarante, M. C. A., & Braga, A. R. C. (2021) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2020.10.043 · Cited by 100 · see citing works

FUNCTIONAL CHARACTERS EVALUATION OF BISCUITS SUBLIMATED WITH PURE PHYCOCYANIN ISOLATED FROM SPIRULINA AND SPIRULINA BIOMASS.

El‐Baky, H. H. A., Baroty, G. S. E., & Ibrahem, E. A. (2015) · PubMed · doi:10.3305/nh.2015.32.1.8804 · Cited by 97 · see citing works

Alcoholic fatty liver disease inhibited the co-expression of Fmo5 and PPARα to activate the NF-κB signaling pathway, thereby reducing liver injury via inducing gut microbiota disturbance

Kong, L., Chen, J., Ji, X., Qin, Q., Yang, H., Liu, D., Li, D., & Sun, M. (2021) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-020-01782-w · Cited by 82 · see citing works

Black elderberry extract attenuates inflammation and metabolic dysfunction in diet-induced obese mice

Farrell, N., Norris, G. H., Ryan, J. A., Porter, C. M., Jiang, C., & Blesso, C. N. (2015) · British Journal Of Nutrition · doi:10.1017/s0007114515002962 · Cited by 71 · see citing works

Loss of resistin ameliorates hyperlipidemia and hepatic steatosis in leptin-deficient mice

Singhal, N. S., Patel, R. T., Qi, Y., Lee, Y.-S., & Ahima, R. S. (2008) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00577.2007 · Cited by 71 · see citing works

Experimental design as a tool for optimization of C-phycocyanin purification by precipitation from Spirulina platensis

Silva, L. A., Kuhn, K. R., Moraes, C. C., Burkert, C. A. V., & Kalil, S. J. (2009) · Journal of the Brazilian Chemical Society · doi:10.1590/s0103-50532009000100003 · Cited by 65 · see citing works

Clinical Safety of a High Dose of Phycocyanin-Enriched Aqueous Extract from Arthrospira (Spirulina) platensis : Results from a Randomized, Double-Blind, Placebo-Controlled Study with a Focus on Anticoagulant Activity and Platelet Activation

Jensen, G. S., Drapeau, C., Lenninger, M. R., & Benson, K. F. (2016) · Journal of Medicinal Food · doi:10.1089/jmf.2015.0143 · Cited by 63 · see citing works

Dose Effects of Orally Administered Spirulina Suspension on Colonic Microbiota in Healthy Mice

Hu, J., Li, Y., Pakpour, S., Wang, S., Pan, Z., Liu, J., Wei, Q., She, J., Cang, H., & Zhang, R. X. (2019) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2019.00243 · Cited by 60 · see citing works

Modulating the Growth, Antioxidant Activity, and Immunoexpression of Proinflammatory Cytokines and Apoptotic Proteins in Broiler Chickens by Adding Dietary Spirulina platensis Phycocyanin

Omar, A. E., Al-Khalaifah, H. S., Osman, A., Gouda, A., Shalaby, S. I., Roushdy, E. M., Abdo, S. A., Ali, S. A., Hassan, A. M., & Amer, S. A. (2022) · Antioxidants · doi:10.3390/antiox11050991 · Cited by 59 · see citing works

The Bioactivities of Phycocyanobilin from Spirulina

Li, Y. (2022) · Journal of Immunology Research · doi:10.1155/2022/4008991 · Cited by 58 · see citing works

Design strategies for C-phycocyanin purification: Process influence on purity grade

de Amarante, M. C. A., Braga, A. R., Sala, L., Moraes, C., & Kalil, S. (2020) · Separation and Purification Technology · doi:10.1016/j.seppur.2020.117453 · Cited by 57 · see citing works

Ameliorative effects of phycocyanin against gibberellic acid induced hepatotoxicity

Hussein, M., Ali, H. A., & Ahmed, M. M. (2015) · Pesticide Biochemistry and Physiology · doi:10.1016/j.pestbp.2015.02.010 · Cited by 48 · see citing works

Resistin and Adiponectin—of Mice and Men

Stümvoll, M., & Häring, H. U. (2002) · Obesity Research · doi:10.1038/oby.2002.162 · Cited by 46 · see citing works

Phycocyanin Improves Reproductive Ability in Obese Female Mice by Restoring Ovary and Oocyte Quality

Wen, X., Han, Z., Liu, S.-J., Hao, X., Zhang, X.-J., Wang, X.-Y., Zhou, C.-J., Ma, Y.-Z., & Liang, C.-G. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.595373 · Cited by 43 · see citing works

Cell Cycle Regulation and Apoptotic Cell Death in Experimental Colon Carcinogenesis: Intervening with Cyclooxygenase-2 Inhibitors

Saini, M. K., & Sanyal, S. N. (2015) · Nutrition and Cancer · doi:10.1080/01635581.2015.1015743 · Cited by 37 · see citing works

Green Extraction Process of Food Grade C-phycocyanin: Biological Effects and Metabolic Study in Mice

Fratelli, C., Bürck, M., Neto, A. P. A., Oyama, L. M., de Rosso, V. V., & Braga, A. R. C. (2022) · Processes · doi:10.3390/pr10091793 · Cited by 34 · see citing works

Mercury Induces Alteration of Energy Transfer in Phycobilisome by Selectively Affecting the Pigment Protein, Phycocyanin, in the Cyanobacterium, Spirulina platensis

Murthy, S. D. S., & Mohanty, P. (1991) · Plant and Cell Physiology · doi:10.1093/oxfordjournals.pcp.a078068 · Cited by 31 · see citing works

Dietary supplement of Yunkang 10 green tea and treadmill exercise ameliorate high fat diet induced metabolic syndrome of C57BL/6 J mice

Zhang, Y., Gu, M., Wang, R., Li, M., Li, D., & Xie, Z. (2020) · Nutrition & Metabolism · doi:10.1186/s12986-020-0433-9 · Cited by 29 · see citing works

Metabolic profile response to administration of epigallocatechin-3-gallate in high-fat-fed mice

Moreno, M. F., Laquila, R. D., Okuda, M. H., Lira, F. S., de Souza, G. I. D. M. H., de Souza, C. T., Telles, M. M., Ribeiro, E. B., do Nascimento, C. M. O., & Oyama, L. M. (2014) · Diabetology & Metabolic Syndrome · doi:10.1186/1758-5996-6-84 · Cited by 23 · see citing works

Chronic intake of 4-Methylimidazole induces Hyperinsulinemia and Hypoglycaemia via Pancreatic Beta Cell Hyperplasia and Glucose Dyshomeostasis

Balakrishnan, R., Velmurugan, G., Freddy, A. J., et al. (2018) · Scientific Reports · doi:10.1038/s41598-018-35071-6 · Cited by 17 · see citing works

Chia flour (Salvia hispanica L.) did not improve the deleterious aspects of hyperlipidic diet ingestion on glucose metabolism, but worsened glycaemia in mice

de Miranda, D. A., da Silva, F. P., Carnier, M., Mennitti, L. V., Figuerêdo, R. G., Hachul, A. C. L., Boldarine, V. T., Neto, N. I. P., Seelaender, M. C. L., Ribeiro, E. B., et al. (2018) · Food Research International · doi:10.1016/j.foodres.2018.12.033 · Cited by 17 · see citing works

Evaluation of glucose dose on intravenous glucose tolerance test traits in Holstein-Friesian heifers

González-Grajales, L. A., Pieper, L., Mengel, S., & Staufenbiel, R. (2017) · Journal of Dairy Science · doi:10.3168/jds.2017-13215 · Cited by 15 · see citing works

Synergistic Beneficial Effects of Resveratrol and Diet on High-Fat Diet-Induced Obesity

Alrob, O. A., Al-Horani, R., Altaany, Z., & Nusair, M. B. (2022) · Medicina · doi:10.3390/medicina58091301 · Cited by 12 · see citing works

Omeprazole and Spirulina Platensis Ameliorate Steatohepatitis in Experimental Nonalcoholic Fatty Liver Disease

El-Boghdady, N. A., Kamel, M. A. E.-N., & El-Shamy, R. M. (2020) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2019.0129 · Cited by 7 · see citing works

Valorization of Microalgae as Multifunctional Protein Sources in Plant-Based Systems: Structural, Functional, and Processing Challenges

Boza, A., Lemos, E., Bürck, M., Gautério, G. V., & Braga, A. R. C. (2026) · Macromol · doi:10.3390/macromol6030054

Research review on physiological activity and its extract and purify technique of phycocyanin from spirulina platensis

Zhang, H. (2008) · Food Science and Technology International

Study of phycocyanin production from Spirulina platensis under different light spectra

Alfredo, W., de Carvalho, J. C., Thomaz‐Soccol, V., de Faria, A. B. B., Ghiggi, V., & Soccol, C. R. (2011) · Brazilian Archives of Biology and Technology · doi:10.1590/s1516-89132011000400005 · Cited by 83 · see citing works

Advances of Studies on the Physiology Activities of Phycocyanin in Spirulina

Lin, P. (2006) · Medical Recapitulate

The spectrum of light and nutrients required to increase the production of phycocyanin Spirulina platensis

Wicaksono, H., Satyantini, W. H., & Masithah, E. D. (2019) · IOP Conference Series Earth and Environmental Science · doi:10.1088/1755-1315/236/1/012008 · Cited by 15 · see citing works

RESEARCH PROGRESS ON EXTRACTION AND PURIFICATION OF PHYCOCYANIN FROM SPIRULINA PLATENSIS

Gao, Z. (2007) · Shipin yanjiu yu kaifa