The DOI matches its Crossref record; 8 of the 8 references it cites were found in a registry or an index.
Role of ginsenosides, the main active components of Panax ginseng , in inflammatory responses and diseases
Open accessAbstract
is one of the most universally used herbal medicines in Asian and Western countries. Most of the biological activities of ginseng are derived from its main constituents, ginsenosides. Interestingly, a number of studies have reported that ginsenosides and their metabolites/derivatives-including ginsenoside (G)-Rb1, compound K, G-Rb2, G-Rd, G-Re, G-Rg1, G-Rg3, G-Rg5, G-Rh1, G-Rh2, and G-Rp1-exert anti-inflammatory activities in inflammatory responses by suppressing the production of proinflammatory cytokines and regulating the activities of inflammatory signaling pathways, such as nuclear factor-κB and activator protein-1. This review discusses recent studies regarding molecular mechanisms by which ginsenosides play critical roles in inflammatory responses and diseases, and provides evidence showing their potential to prevent and treat inflammatory diseases.
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BackgroundDefining the Origins of the NOD-Like Receptor System at the Base of Animal Evolution
Lange, C., Hemmrich, G., Klostermeier, U. C., Lopez-Quintero, J. A., Miller, D. J., Rahn, T., Weiss, Y., Bosch, T. C. G., & Rosenstiel, P. (2011) · Molecular Biology and Evolution · doi:10.1093/molbev/msq349 · Cited by 150
Cited by
Panossian, A. G., Efferth, T., Shikov, A. N., Pozharitskaya, O. N., Kuchta, K., Mukherjee, P. K., Banerjee, S., Heinrich, M., Wu, W., Guo, D., et al. (2021) · Medicinal Research Reviews · doi:10.1002/med.21743 · Cited by 347
Inflammation context in Alzheimer’s disease, a relationship intricate to define
Novoa, C., Salazar, P., Cisternas, P., Gherardelli, C., Vera-Salazar, R., Zolezzi, J. M., & Inestrosa, N. C. (2022) · Biological Research · doi:10.1186/s40659-022-00404-3 · Cited by 206
Ramadhania, Z. M., Yang, D. U., Moektiwardojo, M., Han, Y., Park, J. K., Rupa, E. J., Yang, D. C., Lee, S. J., & Kang, S. C. (2022) · Applied Sciences · doi:10.3390/app13010550 · Cited by 12
Metadata
- Authors
- Kim, J. H., Yi, Y.-S., Kim, M.-Y., & Cho, J. Y.
- Venue
- Journal of Ginseng Research
- Publisher
- Elsevier BV
- Published
- 2017-10
- Volume
- 41
- Issue
- 4
- Pages
- 435-443
- ISSN
- 1226-8453 (ISSN-L)
- OpenAlex
- W2511609099
- Cited by
- 574
- References
- 8
- FWCI
- 12.94
- Type
- journal article
- Language
- en
- Open access
- diamond
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