The DOI matches its Crossref record; 368 of the 371 references it cites were found in a registry or an index.
EASL Clinical Practice Guidelines: Drug-induced liver injury
Abstract
Idiosyncratic (unpredictable) drug-induced liver injury is one of the most challenging liver disorders faced by hepatologists, because of the myriad of drugs used in clinical practice, available herbs and dietary supplements with hepatotoxic potential, the ability of the condition to present with a variety of clinical and pathological phenotypes and the current absence of specific biomarkers. This makes the diagnosis of drug-induced liver injury an uncertain process, requiring a high degree of awareness of the condition and the careful exclusion of alternative aetiologies of liver disease. Idiosyncratic hepatotoxicity can be severe, leading to a particularly serious variety of acute liver failure for which no effective therapy has yet been developed. These Clinical Practice Guidelines summarize the available evidence on risk factors, diagnosis, management and risk minimization strategies for drug-induced liver jury.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Drug-induced liver injury (DILI) is an uncommon adverse reaction to drugs, and other chemicals, including herbal and dietary supplements (HDS).”
From DILI Differences and Similarities between the US and Europe (2026) · cites this paper as [2]
In the citing paper
“The vast majority of cases of DILI occur at therapeutic doses in a small proportion of individuals exposed to the drug, representing an idiosyncratic reaction, and therefore unpredictable based on the drug's mechanism of action and related to the uniqueness of the individual [1,2].”
From DILI Differences and Similarities between the US and Europe (2026) · cites this paper as [2]
In the citing paper
“In pediatric medicine, DILI is a rare clinical situation. However, it has high morbidity and mortality, and it is one of the most common causes of acute liver failure. Furthermore, its diagnosis is clinically challenging due to its low incidence and phenotypic variability [6,7,8].”
From Metabolomic Analysis of Pediatric Patients with Idiosyncratic Drug-Induced Liver Injury According to the Updated RUCAM (2023) · cites this paper as [7]
In the citing paper
“The lack of a reliable diagnostic biomarker and evidence-based treatment paradigm has resulted in limited guidance on how to manage this aspect of DILI.”
From Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report (2023) · cites this paper as [2]
In the citing paper
“The lack of reliable diagnostic biomarkers and an evidence-based treatment paradigm has resulted in limited guidance on how to manage this aspect of DILI.2,25–27”
From Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report (2023) · cites this paper as [2]
In the citing paper
“However, drug rechallenge in DILI cases is potentially dangerous2,75 and is associated with risk of death or requirement for liver transplant.”
From Nomenclature, diagnosis and management of drug-induced autoimmune-like hepatitis (DI-ALH): An expert opinion meeting report (2023) · cites this paper as [2]
In the citing paper
“Although there are some ambiguities regarding how to score certain sections as well as suboptimal reliability, RUCAM can provide systematic and framed guidance for the assessment of patients with suspected DILI and is the most widely used tool [26,27,51,59].”
From Chinese guideline for the diagnosis and treatment of drug-induced liver injury: an update (2024) · cites this paper as [26]
In the citing paper
“High TBil and ALP levels in the second month after an acute DILI episode and the biochemical nonresolution-6 model may help predict the risk of chronic injury and delayed recovery [26,72].”
From Chinese guideline for the diagnosis and treatment of drug-induced liver injury: an update (2024) · cites this paper as [26]
In the citing paper
“Although there are some ambiguities regarding how to score certain sections as well as suboptimal reliability, RUCAM can provide systematic and framed guidance for the assessment of patients with suspected DILI and is the most widely used tool [26,27,51,59].”
From Chinese guideline for the diagnosis and treatment of drug-induced liver injury: an update (2024) · cites this paper as [26]
In the citing paper
“Its potential value in confirming or excluding hepatocellular injury in cases of elevated ALT levels from a suspected extrahepatic origin (e.g., muscle) has been evaluated [26,175].”
From Chinese guideline for the diagnosis and treatment of drug-induced liver injury: an update (2024) · cites this paper as [26]
Citations
Cites
Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma
Larkin, J., Chiarion-Sileni, V., Gonzalez, R., Grob, J. J., Cowey, C. L., Lao, C. D., Schadendorf, D., Dummer, R., Smylie, M., Rutkowski, P., et al. (2015) · New England Journal of Medicine · doi:10.1056/nejmoa1504030 · Cited by 8,157
El-Khoueiry, A. B., Sangro, B., Yau, T., Crocenzi, T. S., Kudo, M., Hsu, C., Kim, T.-Y., Choo, S.-P., Trojan, J., Welling, T. H., et al. (2017) · The Lancet · doi:10.1016/s0140-6736(17)31046-2 · Cited by 4,280
Ekor, M. (2014) · Frontiers in Pharmacology · doi:10.3389/fphar.2013.00177 · Cited by 3,919
Alvarez, F., Berg, P. A., Bianchi, F. B., Bianchi, L., Burroughs, A. K., Cancado, E. L., Chapman, R. W., Cooksley, W. G. E., Czaja, A. J., Desmet, V. J., et al. (1999) · Journal of Hepatology · doi:10.1016/s0168-8278(99)80297-9 · Cited by 2,903
The influence of drug-like concepts on decision-making in medicinal chemistry
Leeson, P. D., & Springthorpe, B. (2007) · Nature Reviews Drug Discovery · doi:10.1038/nrd2445 · Cited by 2,403
Haanen, J. B. A. G., Carbonnel, F., Robert, C., Kerr, K. M., Peters, S., Larkin, J., & Jordan, K. (2017) · Annals of Oncology · doi:10.1093/annonc/mdx225 · Cited by 2,367
Ostapowicz, G., Fontana, R. J., Schiødt, F. V., Larson, A., Davern, T. J., Han, S. H. B., McCashland, T. M., Shakil, A. O., Hay, J. E., Hynan, L., et al. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-137-12-200212170-00007 · Cited by 2,227
Immune-related adverse events with immune checkpoint blockade: a comprehensive review
Michot, J. M., Bigenwald, C., Champiat, S., Collins, M., Carbonnel, F., Postel-Vinay, S., Berdelou, A., Varga, A., Bahleda, R., Hollebecque, A., et al. (2016) · European Journal of Cancer · doi:10.1016/j.ejca.2015.11.016 · Cited by 2,127
Acetaminophen‐induced acute liver failure
Larson, A. M., Polson, J., Fontana, R. J., Davern, T. J., Lalani, E., Hynan, L. S., REISCH, J. S., Schiødt, F. V., Ostapowicz, G., Shakil, A. O., et al. (2005) · Hepatology · doi:10.1002/hep.20948 · Cited by 1,934
Simplified criteria for the diagnosis of autoimmune hepatitis
Hennes, E. M., Zeniya, M., Czaja, A. J., Parés, A., Dalekos, G. N., Krawitt, E. L., Bittencourt, P. L., Porta, G., Boberg, K. M., Hofer, H., et al. (2008) · Hepatology · doi:10.1002/hep.22322 · Cited by 1,901
Research works printed but not linked: 5
- Nicoletti, 2017, Genome-wide association study (GWAS) to identify genetic risk factors that increase susceptibility to antituberculosis drug-induced liver injury (ATDILI) [Abstract], Hepatology, 66, A-25
- Lim, 2008, Association of HLA-B*1502 allele and carbamazepine-induced severe adverse cutaneous drug reaction among Asians, a review, Neurol Asia, 13, 15
- US Food & Drug Administration, 2017, Drugs
- Sanjuan-Jimenez, 2017, Prevalence of hepatitis E markers in Spanish patients with suspected drug-induced liver injury [abstract], Hepatology, 66, 423A
- Fernández-Castañer, 2008, An analysis of the causes, characteristics, and consequences of reexposure to a drug or compound responsible for a hepatotoxicity event, Rev Esp Enfermedades Dig, 100, 278
Cited by
Sorted by citations
Items 701–800 of 1,279
Chiaka-Onyemeze, N. H., Nkwocha, C. C., Edeke, A. A., & Ezeako, E. C. (2025) · International Journal of Plant Based Pharmaceuticals · doi:10.62313/ijpbp.2025.250 · Cited by 2
Roehlen, N., & Thimme, R. (2025) · DMW - Deutsche Medizinische Wochenschrift · doi:10.1055/a-2301-8259 · Cited by 2
Dumitru-Martoiu, M.-M., Petrescu, S., & Panea, C. (2025) · Reports — Medical Cases Images and Videos · doi:10.3390/reports8020038 · Cited by 2
Wischneski, I., Barreto, P. A. P. M., Tardelli, V. S., & Roza, T. H. (2025) · Springer eBooks · doi:10.1007/978-3-031-85519-1_37 · Cited by 2
Trampert, D. C. (2025) · Journal of Hepatology · doi:10.1016/j.jhep.2025.04.022 · Cited by 2
iDILI-MT: identifying drug-induced liver injury compounds with a multi-head Transformer
Zheng, W., & Lai, F. (2025) · PeerJ Computer Science · doi:10.7717/peerj-cs.2973 · Cited by 2
Cholestatic Drug-Induced Liver Injury From Rad-140 Successfully Treated With Corticosteroids
Niazi, B., Quach, B., Fisher, K. W., & Peeraphatdit, T. B. (2025) · ACG Case Reports Journal · doi:10.14309/crj.0000000000001803 · Cited by 2
Advances in mechanistic investigation and treatment of steroid-refractory ICI-induced liver injury
Hu, H., Shen, X., & Chen, J. (2025) · Clinical and Experimental Medicine · doi:10.1007/s10238-025-01721-z · Cited by 2
Jiang, C., Yang, F.-L., Peng, W.-T., Li, Y., Peng, S., Gu, H.-M., & Fu, L. (2025) · Therapeutic Advances in Medical Oncology · doi:10.1177/17588359251357685 · Cited by 2
Moreno‐Torres, M., López-Pascual, E., Moro, E., Rapisarda, A. S., Lindeman, B., Verhoeven, A., Luechtefeld, T. H., Serrano‐Candelas, E., Dirven, H. A. A. M., Vinken, M., et al. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.118459 · Cited by 2
Gatzios, A., Marchandise, L., Hagström, H., Schattenberg, J. M., Rodrigues, R. M., Vanhaecke, T., & Boeckmans, J. (2025) · Liver International · doi:10.1111/liv.70287 · Cited by 2
Huang, X., Lian, Z., Qi, S., & Yu, H. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1643871 · Cited by 2
Treatment of patients with hyperthyroidism and liver failure: a retrospective cohort study
Li, Z., Li, X., Shao, X., Xu, Q., Wu, Y., & Liu, Y. (2025) · BMC Gastroenterology · doi:10.1186/s12876-025-04286-z · Cited by 2
Meunier, L., Delire, B., Martin, E. D., Lebossé, F., Anty, R., Dumortier, J., Houssel‐Debry, P., Delwaide, J., Duclos‐Vallée, J., Lutu, A., et al. (2025) · Clinical Gastroenterology and Hepatology · doi:10.1016/j.cgh.2025.10.024 · Cited by 2
Self-citationKirchner, T., Junge, N., Henjes, N., Loges, S., Yüksel, M., Jańczyk, W., Lalanne, C., Zachou, K., Oo, Y. H., Gournay, J., et al. (2025) · JHEP Reports · doi:10.1016/j.jhepr.2025.101706 · Cited by 2
Gao, W., Yan, S., Zhang, L., Chen, L., Che, J., Huang, W., Chen, Y., Liu, A., Zhu, Y., Yang, Y., et al. (2026) · Journal of Advanced Research · doi:10.1016/j.jare.2025.12.012 · Cited by 2
Parinitha, A., & Lakshmi, A. J. (2026) · ACS Nutrition Science · doi:10.1021/acsnutrsci.5c00020 · Cited by 2
A Macrophage-Specific PET Tracer for Grading Acute Liver Injury
Zhang, X., Wang, G., Wang, T., Li, J., Liu, N., & Su, X. (2026) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.5c03042 · Cited by 2
Antiseizure Treatments and Liver Injury: Expect (and Prevent) the Unexpected
Bunch, M. E., Klocke, S., Woodrich, N., Barritt, A. S., & Eyal, S. (2026) · Epiliepsy currents/Epilepsy currents · doi:10.1177/15357597251403348 · Cited by 2
Ling, J., Zhang, S., Lin, J., Xu, Z., Xu, R., Lv, Q., Zhang, K., Liu, S., Jie, G., Hua, C., et al. (2026) · Interdisciplinary medicine · doi:10.1002/inmd.70091 · Cited by 2
Zhang, J., Yan, M., Tang, Y., Liu, M., Yao, W., Zhang, Q., & Chen, H. (2026) · ACS Nano · doi:10.1021/acsnano.5c18314 · Cited by 2
Kirchner, T., Dalekos, G. N., Zachou, K., Robles‐Díaz, M., Andrade, R. J., Sebode, M., Lohse, A. W., Janik, M. K., Milkiewicz, P., Kolev, M., et al. (2026) · Liver International · doi:10.1111/liv.70571 · Cited by 2
Self-citationHo, A. Z. T., Law, J. Z. F., Wang, A., Lim, D. Y. Z., & Ong, J. (2026) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1002/phar.70131 · Cited by 2
Song, Z., He, Y., Zhang, W., Lian, W., Pan, Y., Ma, J., Zhao, Y., Huang, T., Zhuge, Y., & Lin, G. (2026) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2026.03.023 · Cited by 2
Matilla‐Cabello, G., Remesal-Doblado, Á., Çelebi-Çınar, M., Bodoque-García, A., Metin, F. B., Rezaei, A., Aftab, A. M., Santos‐Fernández, R. L. D. L., Segovia‐Zafra, A., Álvarez‐Álvarez, I., et al. (2026) · Acta Pharmaceutica Sinica B · doi:10.1016/j.apsb.2026.03.030 · Cited by 2
Self-citationWang, P., He, Q., Xu, Y., Chen, Y., Zeng, X., Deng, K., & Xie, Q. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119268 · Cited by 2
Ivashkin, V. T., Drapkina, О. M., Raikhelson, K. L., Okovityi, S. V., Maevskaya, M. V., Grechishnikova, V. R., Жаркова, М. С., Khlynova, O. V., Gladkov, O. A., Deeva, Т. A., et al. (2026) · Russian Journal of Gastroenterology Hepatology Coloproctology · doi:10.22416/1382-4376-2026-36-1-70-146 · Cited by 2
Licata, A., Ciriminna, S., Tulone, O., Cammilleri, M., Cilona, L., Chianetta, R., Giannitrapani, L., Citarrella, R., Barbagallo, M., & Soresi, M. (2026) · Internal and Emergency Medicine · doi:10.1007/s11739-026-04425-8 · Cited by 2
Tirzepatide-Associated Severe Hepatocellular Injury: A Case Report and Diagnostic Considerations
Kim, D. G., Yoo, J., Kim, S. G., & Kim, Y. S. (2026) · Diagnostics · doi:10.3390/diagnostics16152359 · Cited by 2
Hayashi, M., Abe, K., Fujita, M., Takahashi, A., Kobayashi, Y., Hashimoto, Y., & Ohira, H. (2020) · Clinical Journal of Gastroenterology · doi:10.1007/s12328-020-01253-x · Cited by 2
Pathogenetic mechanisms of drug-induced liver damage
Кочетков, А. И., Сергеевна, А. Е., & Ostroumova, O. D. (2020) · Siberian medical review · doi:10.20333/2500136-2020-6-36-50 · Cited by 2
Prednisolone: role in amoxicillin–clavulanate-induced cholestatic liver injury
Qiyu, M. L., Chigozie, R., Khan, I., & O'Mara, G. (2021) · BMJ Case Reports · doi:10.1136/bcr-2020-239488 · Cited by 2
Phương, N. T. T., Hoang, D. V., Khuê, P. M., & Thanh, H. N. (2021) · The Journal of Clinical Pharmacology · doi:10.1002/jcph.1955 · Cited by 2
Research status and progress of drug induced liver injury
Chi, Z.-C. (2021) · World Chinese Journal of Digestology · doi:10.11569/wcjd.v29.i16.915 · Cited by 2
Ikewuchi, C. C., Ikewuchi, J. C., & Ifeanacho, M. O. (2021) · Biotechnologia · doi:10.5114/bta.2021.108726 · Cited by 2
Common Gastrointestinal Medications Implicated in Drug‐Induced Liver Injury
Garg, K., Kramer, J. B., & Eswaran, S. L. (2021) · Clinical Liver Disease · doi:10.1002/cld.1110 · Cited by 2
Kang, S.-W., Hong, S.-E., Park, J., Kwon, S., Yoon, S.-H., Kim, K.-I., Lee, B., & Jung, H.-J. (2021) · The Journal of Internal Korean Medicine · doi:10.22246/jikm.2021.42.4.590 · Cited by 2
Drug-Induced Liver Injury in Older Adults
Miller, E., Abu‐Sbeih, H., & Chalasani, N. (2021) · Springer eBooks · doi:10.1007/978-3-030-30192-7_53 · Cited by 2
Efficacy and safety of low-dose rifampicin in patients with benign intrahepatic cholestasis
Guo, X., Li, X., Yan, Y., Cao, H., Zhang, Y., & Lai, J. (2022) · Liver Research · doi:10.1016/j.livres.2022.08.006 · Cited by 2
Infliximab (IFX)-Biosimilar Induced Drug-Induced Liver Injury (DILI): A Case Report
Zachou, M., Pikramenos, K., Panoutsakou, M., Lalla, E., & Ανδρουτσάκος, Θ. (2022) · Cureus · doi:10.7759/cureus.32525 · Cited by 2
Yustin, W. E. F., Kusumawardani, I. A. J. D., Candrawati, N. W., & Rai, I. B. N. (2022) · Health & Medical Journal · doi:10.33854/heme.v4i3.998 · Cited by 2
Ravindra, B. S., Lahoti, D., & Das, K. (2022) · International Journal of Scientific Reports · doi:10.18203/issn.2454-2156.intjscirep20223372 · Cited by 2
Holistic Metabolomic Profiling of Chronic versus Acute Drug-induced Liver Injury
Wang, J., Shi, Z., Wei, L., Huang, A., Zhai, X., Niu, M., Xu, J., Jing, J., He, T., Gao, Y., et al. (2023) · Future Integrative Medicine · doi:10.14218/fim.2022.00057 · Cited by 2
The Role of Gold Nanorods in Detecting Circulating microRNAs as Biomarkers in Liver Diseases
Yang, S., Liu, C., Ji, X., Chen, X., Wang, Y., & Rong, T. (2023) · Journal of Biomedical Nanotechnology · doi:10.1166/jbn.2023.3676 · Cited by 2
Khan, M. Q., Hassan, S. M., Lizaola‐Mayo, B., Bhat, M., & Watt, K. D. S. (2023) · Hepatology · doi:10.1097/hep.0000000000000674 · Cited by 2
Mederacke, Y., Mederacke, I., Bock, K., & Wedemeyer, H. H. (2024) · Zeitschrift für Gastroenterologie · doi:10.1055/a-2150-2077 · Cited by 2
Yang, H., Lin, M., Liu, M., Gu, H., Li, D., Shi, Y., & Hou, X. (2024) · Scientific Reports · doi:10.1038/s41598-024-54314-3 · Cited by 2
Arzneimittelinduzierte immunvermittelte Leberschädigung
Weber, S. (2024) · Die Innere Medizin · doi:10.1007/s00108-024-01669-4 · Cited by 2
Drug-induced autoimmune-like hepatitis
Васильевна, В. Г., Nikitin, A. V., Андреевна, С. Т., & Спартаковна, К. В. (2024) · Russian Journal of Evidence-Based Gastroenterology · doi:10.17116/dokgastro20241301158 · Cited by 2
Managing unpredictable challenge of a liver injury in ornidazole use: A case report
Memiş, A. C., Yazıcı-alcan, S., Temiz, S. G., Başar, F., & Arslan, K. (2024) · Medical Reports · doi:10.1016/j.hmedic.2024.100097 · Cited by 2
Xiong, Q., Zou, L., Chen, Z.-J., Liu, H., Lu, Y., Liu, D.-X., & Yang, Y. (2024) · The Turkish Journal of Gastroenterology · doi:10.5152/tjg.2024.23512 · Cited by 2
Chiang, H., & Wu, I. (2024) · The American Journal of the Medical Sciences · doi:10.1016/j.amjms.2024.08.019 · Cited by 2
Efficacy of concomitant therapy with ademetionine in antitumor drug therapy: A review
Ognerubov, N. A. (2024) · Consilium Medicum · doi:10.26442/20751753.2024.6.202857 · Cited by 2
Yuan, Z., Peng, J., Shu, Z., Qin, X., & Zhong, J. (2024) · Scientific Reports · doi:10.1038/s41598-024-66952-8 · Cited by 2
Tsai, Y., Chen, C., Wu, Y., Hung, C.-L., Fang, M.-C., Yu, I., Sheu, J., Hsu, Y., & Lin, S. (2024) · Cell Biology and Toxicology · doi:10.1007/s10565-024-09915-z · Cited by 2
Huang, Y., Huang, Y.-M., Lee, N., Lee, P., & Ho, Y. (2025) · Drugs - Real World Outcomes · doi:10.1007/s40801-024-00475-6 · Cited by 2
Survey on Awareness of Tamoxifen-Induced Liver Injury Among Hepatologists in Japan
Ueno, M., Ueno, A., Yamaguchi, K., Abe, K., Abe, M., Kagawa, T., Kakisaka, K., Ichimoto, K., Kamimura, H., Komiyama, Y., et al. (2025) · Kanzo · doi:10.2957/kanzo.66.7 · Cited by 2
Kilianova, Z., Stollárová, N., Pivackova, L. B., Křenek, P., Göböová, M., Rihova, Z. J., Aziz, E. K., Kuželički, N. K., Dóka, G., & Klimas, J. (2024) · Pharmacogenomics · doi:10.1080/14622416.2025.2456449 · Cited by 2
Permatasari, D., AINI, N., & Yosmar, R. (2025) · International Journal of Applied Pharmaceutics · doi:10.22159/ijap.2025.v17s1.09 · Cited by 2
Kitano, Y., Okamoto, K., SHIBAHARA, K., Tokimitsu, Y., & Maeda, Y. (2025) · International Cancer Conference Journal · doi:10.1007/s13691-025-00765-y · Cited by 2
A New Discovery: Corydalis yanhusuo Causes Idiosyncratic Hepatotoxicity and Its Potential Mechanisms
Guo, L., Lin, L., Ling, J., Zhu, S., Li, X., Long, M., Xu, Y., Hu, Z., Niu, M., Zhao, X., et al. (2025) · Biomedical Chromatography · doi:10.1002/bmc.70093 · Cited by 2
Pathophysiological Differences and Differential Diagnosis of Autoimmune and Drug-Induced Hepatitis
Zeni, N., Cristofani, A., Piano, S. S., Bolognesi, M., & Romano, A. (2025) · Livers · doi:10.3390/livers5020022 · Cited by 2
Hepatotoxicity associated with vedolizumab: case report in a patient with ulcerative colitis
Crosewski, N. I., Pereira, A. H. M., Kotze, L. R., Pedroso, M. L. A., Kampa, K. C., Rosevics, L., Furlan, T. K., & Ramos, O. (2025) · European Journal of Gastroenterology & Hepatology · doi:10.1097/meg.0000000000003022 · Cited by 2
Ahmad, J. (2025) · Indian Journal of Gastroenterology · doi:10.1007/s12664-025-01860-x · Cited by 2
Xiong, Y., Cai, X., Lai, X., Wang, Y., Xin, H., Song, W., Lv, F., Guo, X., Yang, G., & Wu, Y. (2025) · Frontiers in Public Health · doi:10.3389/fpubh.2025.1566260 · Cited by 2
Idris, A., Hassan, M., & Tesfaye, Y. (2022) · Pharmaceutical Sciences and Drug Design · doi:10.51847/dsb59dlpxl · Cited by 2
Chronic autoimmune hepatitis triggered by olmesartan
Mínguez, D. R., García, M. L. G., & Fernández‐Rodríguez, C. (2020) · Gastroenterología y Hepatología · doi:10.1016/j.gastrohep.2020.03.018 · Cited by 2
Hydrochlorothiazide-induced hepatotoxicity: A rare case of DILI
Malézieux, E., Meunier, L., Rivière, B., & Larrey, D. G. (2021) · Clinics and Research in Hepatology and Gastroenterology · doi:10.1016/j.clinre.2020.101599 · Cited by 2
Self-citationBai, Y., Liang, Y., Wang, F., Chen, L., Zhao, Y., Zhao, S., Zhu, Y., Dong, Y., Liang, G., Chen, D., et al. (2021) · Annals of Translational Medicine · doi:10.21037/atm-21-2237 · Cited by 2
Wakabayashi, T., Osaki, A., Watanabe, Y., Yamazaki, S., Yokoyama, H., Kimura, K., Sato, M., Takaku, K., Aiba, T., Furukawa, K., et al. (2021) · Kanzo · doi:10.2957/kanzo.62.630 · Cited by 2
Skrypnyk, R. І., & Маслова, Г. С. (2021) · Актуальні проблеми сучасної медицини Вісник Української медичної стоматологічної академії · doi:10.31718/2077-1096.21.4.63 · Cited by 2
Biological Activity of Halogen-Containing Derivatives of N-Substituted Quinone Imines
(2020) · Biointerface Research in Applied Chemistry · doi:10.33263/briac106.70707076 · Cited by 2
Aithal, G. P. (2019) · Medicine · doi:10.1016/j.mpmed.2019.08.005 · Cited by 2
Self-citationClinical course and outcomes of COVID-19 patients with chronic obstructive pulmonary disease
Bai, Y., Wen, L., Zhao, Y., Li, J., Guo, C., Zhang, X., Yang, J., Dong, Y., Ma, L., Liang, G., et al. (2022) · Medicine · doi:10.1097/md.0000000000029141 · Cited by 2
Drug-Induced Liver Injury From Sacubitril-Valsartan Versus a Single Dose of Acarbose
Achuthanandan, S., Dhaliwal, A., & Patti, R. (2022) · Cureus · doi:10.7759/cureus.27005 · Cited by 2
Autoimmune hepatitis: Challenges and novelties
Olivas, I., Rodríguez‐Tajes, S., & Londoño, M. (2022) · Medicina Clínica (English Edition) · doi:10.1016/j.medcle.2022.08.008 · Cited by 2
[Clinical characteristics and prognosis analysis of 498 cases with drug-induced liver injury].
Yang, X., Tu, R.-F., & Yang, J. (2022) · PubMed Central · doi:10.3760/cma.j.cn501113-20200720-00399 · Cited by 2
Leberfunktionsstörungen bei geriatrischen Patienten
Kasper, P., Tacke, F., Heppner, H. J., & Michels, G. (2022) · Zeitschrift für Gerontologie und Geriatrie · doi:10.1007/s00391-022-02037-3 · Cited by 2
Cholestatic liver injury: A rare but fatal complication during and after COVID-19 infection
Wongtanasarasin, W. (2022) · World Journal of Virology · doi:10.5501/wjv.v11.i6.435 · Cited by 2
The peculiarities of some gastroenterological diseases in elderly patients
Kolesnikova, O. V., & Radchenko, A. O. (2019) · Modern Gastroenterology · doi:10.30978/mg-2019-4-23 · Cited by 2
Injúria hepática induzida por medicamentos em pacientes pediátricos
Iwaki, M. V., Gonçalves, S. T., Louro, E., Furuzawa, T. A., dos Santos, F. C. S., Moura, D. R. D. O., Cremer, E., Batistela, V. R., Silva-Comar, F. M. D. S., & Cuman, R. K. N. (2023) · Research Society and Development · doi:10.33448/rsd-v12i4.38393 · Cited by 2
Understanding liver function tests: part 2
Parsons, G. (2023) · Prescriber · doi:10.1002/psb.2086 · Cited by 2
Hepatotoxicidad por tamsulosina / dutasterida: reporte de un caso probable
Yance, S., & Montes, P. (2023) · Revista de Gastroenterología del Perú · doi:10.47892/rgp.2023.433.1544 · Cited by 2
Approach to Abnormal Liver Biochemistries in the Primary Care Setting
Rajesh, R., Sangameshwar, A., Tan, Y. Y., Jun, K. T. K., Tham, T. Y., & Cheah, M. C. C. (2024) · Cureus · doi:10.7759/cureus.56541 · Cited by 2
Drug-induced injury secondary to terbinafine
TEIXEIRA, C. M., AMARO, A. M., Alexandra, D. I. A. S., de Brito, A. P., & DUARTE, A. (2024) · Gazzetta Medica Italiana Archivio per le Scienze Mediche · doi:10.23736/s0393-3660.23.05023-4 · Cited by 2
Drug-induced liver injury associated with savolitinib: a novel case report and causality assessment
Gu, F., Yang, P., Li, L., & Li, C. (2024) · BMC Pulmonary Medicine · doi:10.1186/s12890-024-03201-8 · Cited by 2
Shen, T., Mao, Y., & Chen, C. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.08.047 · Cited by 2
Drug-induced liver injury from herbal and dietary supplements: a problem in the East and West alike
Nash, E., Chetwood, J. D., Strasser, S. I., & Liu, K. (2022) · Hepatology International · doi:10.1007/s12072-021-10289-1 · Cited by 2
Better understanding of ICI-induced cholangitis for better management
Meunier, L., & Maria, A. T. J. (2023) · Journal for ImmunoTherapy of Cancer · doi:10.1136/jitc-2023-006730 · Cited by 2
Elvir-Lazo, O. L., Romero-Navarro, A. L., & White, P. F. (2024) · Journal of Clinical Anesthesia · doi:10.1016/j.jclinane.2024.111553 · Cited by 2
Case of severe liver damage in 12‑year‑old child with intentional overdose of paracetamol
Сергеевич, П. С., Teplova, N. V., Bryusov, G. P., Komarova, T. N., Rumyantsev, A. G., Tatarova, I. N., Donush, E. K., Tsimbalova, E. A., Kostyleva, M. N., Gratsianskaya, A. N., et al. (2023) · Medical alphabet · doi:10.33667/2078-5631-2023-18-28-33 · Cited by 1
Aloe vera Induce Acute Liver Injury and Chronic Liver Disease: Case Report
Rached, A. A., Farid, A. A., Zaiter, A., & Joyce, S. (2023) · World Journal of Case Reports and Clinical Images · doi:10.51521/wjcrci.2023.2104 · Cited by 1
Fosfomycin-Induced Liver Injury: A Case Report
Ribeiro, R., Antas, J., Monteiro, A. P., Magalhães, J., Miranda, D., & Cruz, C. (2024) · Cureus · doi:10.7759/cureus.55508 · Cited by 1
Paracetamol is both a friend and a foe: What should a pediatrician know? A clinical case
Zakharova, I. N., Berezhnaya, I. V., & Sugian, N. G. (2024) · Pediatrics Consilium Medicum · doi:10.26442/26586630.2024.3.202961 · Cited by 1
Pakhomova, I. G. (2024) · Meditsinskiy sovet = Medical Council · doi:10.21518/ms2024-343 · Cited by 1
Typical yellow urticaria with uncommon cause
Gao, H.-K., Wang, L., & Tan, C. (2025) · British Journal of Dermatology · doi:10.1093/bjd/ljaf002 · Cited by 1
Pharmacological Therapy for Drug-Induced Liver Injury
Wu, Q., Wang, T., Li, Q., Gao, F., Liu, C., & Qi, X. (2025) · IntechOpen eBooks · doi:10.5772/intechopen.1009951 · Cited by 1
LKM Immunofluorescence Is Associated with DILI, Especially after Metamizole Intake
Bock, K., Engel, B., Jaeckel, E., Wedemeyer, H. H., Mederacke, I., & Mederacke, Y. (2025) · Digestive Diseases · doi:10.1159/000545507 · Cited by 1
Bihari, C., Sharma, S., Giri, A., Yadav, R. P., Baweja, S., Rastogi, A., & Sarin, S. K. (2025) · Hepatology International · doi:10.1007/s12072-025-10814-6 · Cited by 1
Hepatotoxicity of Chemotherapy and Immune Checkpoint Inhibitors
Block, P. D., & Assis, D. N. (2025) · Clinics in Liver Disease · doi:10.1016/j.cld.2025.03.006 · Cited by 1
Metadata
- Authors
- Andrade, R. J., Aithal, G. P., Björnsson, E. S., Kaplowitz, N., Kullak-Ublick, G. A., Larrey, D., & Karlsen, T. H.
- ORCID
- Venue
- Journal of Hepatology
- Publisher
- Elsevier BV
- Published
- 2019-06
- Volume
- 70
- Issue
- 6
- Pages
- 1222-1261
- ISSN
- 0168-8278 (ISSN-L)
- OpenAlex
- W2924328881
- Semantic Scholar
- 6d774d1c570eef200451a1e8a8f5655c367a4eaf
- Cited by
- 1,276
- References
- 371
- Citations by year
- 2026: 243 · 2025: 211 · 2024: 175 · 2023: 159 · 2022: 158 · 2021: 184 · 2020: 117 · 2019: 27
- FWCI
- 78.91
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Hepatology (publishedVersion)
- PubMed (publishedVersion)
- Funders
- European Cooperation in Science & Technology
- Topics
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Drug-Induced Hepatotoxicity and Protection
- Health Sciences › Medicine › Hepatology › Liver Diseases and Immunity
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Toxicology › Pharmacovigilance and Adverse Drug Reactions
- Keywords
- drug-induced liver injury, idiosyncratic drug-induced liver injury, hepatotoxicity, acute liver failure, risk factors, diagnosis, risk minimization
- MeSH terms
- Adult, Aged, Fatty Liver, Female, Histocompatibility Testing, Humans, Liver Neoplasms, Male, Middle Aged, Mitochondria, Risk Factors, Chemical and Drug Induced Liver Injury
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review