The DOI matches its Crossref record; 208 of the 208 references it cites were found in a registry or an index.
Hepatic encephalopathy: Novel insights into classification, pathophysiology and therapy
Open accessAbstract
Hepatic encephalopathy (HE) is a frequent and serious complication of both chronic liver disease and acute liver failure. HE manifests as a wide spectrum of neuropsychiatric abnormalities, from subclinical changes (mild cognitive impairment) to marked disorientation, confusion and coma. The clinical and economic burden of HE is considerable, and it contributes greatly to impaired quality of life, morbidity and mortality. This review will critically discuss the latest classification of HE, as well as the pathogenesis and pathophysiological pathways underlying the neurological decline in patients with end-stage liver disease. In addition, management strategies, diagnostic approaches, currently available therapeutic options and novel treatment strategies are discussed.
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Cites
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Self-citationAlterations of the human gut microbiome in liver cirrhosis
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The NIH Human Microbiome Project
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Rifaximin Treatment in Hepatic Encephalopathy
Bass, N. M., Mullen, K. D., Sanyal, A., Poordad, F., Neff, G., Leevy, C. B., Sigal, S., Sheikh, M. Y., Beavers, K., Frederick, T., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa0907893 · Cited by 1,300
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Altered profile of human gut microbiome is associated with cirrhosis and its complications
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Cited by
Ginès, P., Krag, A., Abraldes, J. G., Solà, E., Fabrellas, N., & Kamath, P. S. (2021) · The Lancet · doi:10.1016/s0140-6736(21)01374-x · Cited by 1,663
Pentón-Rol, G., Marín-Prida, J., & McCarty, M. F. (2021) · Current Neuropharmacology · doi:10.2174/1570159x19666210408123807 · Cited by 73
Kronsten, V. T., & Shawcross, D. L. (2022) · Analytical Biochemistry · doi:10.1016/j.ab.2021.114437 · Cited by 27
Metadata
- Authors
- Rose, C. F., Amodio, P., Bajaj, J. S., Dhiman, R. K., Montagnese, S., Taylor-Robinson, S. D., Vilstrup, H., & Jalan, R.
- Venue
- Journal of Hepatology
- Publisher
- Elsevier BV
- Published
- 2020-12
- Volume
- 73
- Issue
- 6
- Pages
- 1526-1547
- ISSN
- 0168-8278 (ISSN-L)
- OpenAlex
- W3094334480
- Cited by
- 470
- References
- 208
- FWCI
- 25.97
- Type
- journal article
- Language
- en
- Open access
- hybrid
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- The paper
- Rose, C. F., Amodio, P., Bajaj, J. S., Dhiman, R. K., Montagnese, S., Taylor-Robinson, S. D., Vilstrup, H., & Jalan, R. (2020). Hepatic encephalopathy: Novel insights into classification, pathophysiology and therapy. Journal of Hepatology. https://doi.org/10.1016/j.jhep.2020.07.013
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
