Cited by 5Dermatologic Treatments and ResearchOrthopedic Surgery and RehabilitationPeripheral Nerve Disorders

The DOI matches its Crossref record; 38 of the 39 references it cites were found in a registry or an index.

The effect of Centella Asiatica cream on scar development in patients who underwent open carpal tunnel release surgery

Balevi, Mustafa, Balevi, Ali·2023·Journal of Hand Therapy

Abstract

Aim To evaluate the efficacy of the Centella asiatica extract in a cream preparation for the prevention of scar tenderness formation in patients who underwent conventional open carpal tunnel release (CTR) surgery. Material and methods A total of 280 patients with carpal tunnel syndrome who underwent CTR surgery were individually randomized into the intervention (n = 140) and control (n = 140) groups. In the intervention group, a petroleum cream mixture consisting of 1% Centella asiatica extract was applied to the patients' wrist for 6 months after the sutures were removed. In the control group, no intervention was applied. The Vancouver Scar Scale (VSS), Quick Disabilities of Arm, Shoulder and Hand (QuickDASH) functional score, and Visual Analog Scale (VAS) satisfaction scores were assessed preoperatively and postoperatively. Follow-up evaluations were scheduled at 1, 3 and 6 months after CTR surgery. Results The overall VSS score of the intervention group significantly improved at 3-6 months (-1.260, p = .040). At 6 months after surgery, the mean QuickDASH functional score was 18.54 (range 0.00-63.64, SD 17.4) in the intervention group and 28.70 ± 12 (range: 2.27-40.91) in the control group (p Conclusion The Centella asiatica cream applied to the wrist after CTR surgery was found to be beneficial in preventing scar tenderness in the thenar and hypothenar regions of the hand.

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Crossref · 10.1016/j.jht.2022.11.001

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Citations

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Research works printed but not linked: 3

  1. Angst, 2011, Arthritis Care Res (Hoboken), 63, S174
  2. Jugovac, 2004, Carpal tunnel release by limited palmar incision versus, Hand Surg, 9, 35
  3. Somboonwong, 2012, Wound healing activities of different extracts of Centella asiatica in incision and burn wound models: an experimental animal study, MC Complement Altern Med, 12, 103, 10.1186/1472-6882-12-103 · DOI · Paper page

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Metadata

Authors
Balevi, M., & Balevi, A.
Affiliations
  • Konya Numune Hastanesi (TR)
  • Istanbul Medipol University (TR)
Corresponding author
Balevi, Mustafa
Venue
Journal of Hand Therapy
Publisher
Elsevier BV
Published
2023-10
Volume
36
Issue
4
Pages
962-966
ISSN
0894-1130 (ISSN-L)
OpenAlex
W4323979968
Cited by
3
References
39
Citations by year
2025: 1 · 2024: 2
FWCI
0.83
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Hand Therapy (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Dermatology › Dermatologic Treatments and Research
  • Health Sciences › Medicine › Surgery › Orthopedic Surgery and Rehabilitation
  • Health Sciences › Medicine › Clinical Neurology › Peripheral Nerve Disorders
Keywords
Centella asiatica, scar tenderness, carpal tunnel release, carpal tunnel syndrome, topical cream, Vancouver Scar Scale, QuickDASH, patient satisfaction
MeSH terms
Carpal Tunnel Syndrome, Cicatrix, Humans, Plant Extracts, Triterpenes, Treatment Outcome, Centella

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