The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019
Open accessAbstract
OBJECTIVE: To determine the dynamic changes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA in respiratory and fecal specimens in children with coronavirus disease 2019 (COVID-19). METHODS: From January 17, 2020 to February 23, 2020, three paediatric cases of COVID-19 were reported in Qingdao, Shandong Province, China. Epidemiological, clinical, laboratory, and radiological characteristics and treatment data were collected. Patients were followed up to March 10, 2020, and dynamic profiles of nucleic acid testing results in throat swabs and fecal specimens were closely monitored. RESULTS: Clearance of SARS-CoV-2 in respiratory tract occurred within two weeks after abatement of fever, whereas viral RNA remained detectable in stools of pediatric patients for longer than 4 weeks. Two children had fecal SARS-CoV-2 undetectable 20 days after throat swabs showing negative, while that of another child lagged behind for 8 days. CONCLUSIONS: SARS-CoV-2 may exist in children's gastrointestinal tract for a longer time than respiratory system. Persistent shedding of SARS-CoV-2 in stools of infected children raises the possibility that the virus might be transmitted through contaminated fomites. Massive efforts should be made at all levels to prevent spreading of the infection among children after reopening of kindergartens and schools.
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Bogler, A., Packman, A., Furman, A., Gross, A., Kushmaro, A., Ronen, A., Dagot, C., Hill, C., Vaizel-Ohayon, D., Morgenroth, E., et al. (2020) · Nature Sustainability · doi:10.1038/s41893-020-00605-2 · Cited by 312
COVID-19 and its Modes of Transmission
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The Importance of Advancing Severe Acute Respiratory Syndrome Coronavirus 2 Vaccines in Children
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Metadata
- Authors
- Xing, Y.-H., Ni, W., Wu, Q., Li, W.-J., Li, G.-J., Wang, W.-D., Tong, J.-N., Song, X.-F., Wing-Kin Wong, G., & Xing, Q.-S.
- Venue
- Journal of Microbiology, Immunology and Infection
- Publisher
- Elsevier BV
- Published
- 2020-06
- Volume
- 53
- Issue
- 3
- Pages
- 473-480
- ISSN
- 1684-1182 (ISSN-L)
- OpenAlex
- W3013636271
- Cited by
- 298
- References
- 26
- FWCI
- 8.48
- Type
- journal article
- Language
- en
- Open access
- gold
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- Xing, Y.-H., Ni, W., Wu, Q., Li, W.-J., Li, G.-J., Wang, W.-D., Tong, J.-N., Song, X.-F., Wing-Kin Wong, G., & Xing, Q.-S. (2020). Prolonged viral shedding in feces of pediatric patients with coronavirus disease 2019. Journal of Microbiology, Immunology and Infection. https://doi.org/10.1016/j.jmii.2020.03.021
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