Cited by 9Digital Mental Health InterventionsMusculoskeletal pain and rehabilitationPediatric Pain Management Techniques

Internet-Delivered Psychological Pain-Management for Young Adults With Chronic Pain: An Investigation of Clinical Trial Data

Open access
Dudeney, Joanne, Scott, Amelia J., Hathway, Taylor, Bisby, Madelyne A., Harte, Nicole, Titov, Nickolai, Dear, Blake F.·2024·The Journal of Pain

Abstract

Young adults report chronic pain at rates of around 12% but lack access to clinical services. There is interest in learning how this emerging adult population engages with and responds to treatment. Using data from young adults aged 18 to 30 years (Mage = 25.8, SD = 3.2), taken from 4 previous randomised controlled trials, the current study investigated the feasibility, acceptability, and efficacy of an internet-delivered psychological pain-management intervention for young adults with chronic pain. We compared young adults in a treatment group (n = 104) with 1) a young-adult wait-list control group (n = 48), and 2) a treatment group reflecting the average-aged participant from the previous trials (39–63 years, n = 561). Feasibility was determined through treatment engagement, adherence and completion, and acceptability through a treatment satisfaction measure. Clinical outcomes were disability, pain intensity, anxiety, and depression; assessed at pre-treatment, post-treatment, and 3-month follow-up. Generalised estimation equation analyses were undertaken, using multiple imputations to account for missing data. Young adults had high engagement and acceptability ratings, though 34% did not complete the intervention. The treatment group significant improved across all outcomes, compared with control, with improvements maintained at follow-up. Post-treatment improvements were equivalent for young-adult and average-aged adult treatment groups, with no significant differences in feasibility or acceptability outcomes. Findings indicate young adults can engage with and show improvements following a psychological pain-management intervention designed for all adults with chronic pain. Future research is encouraged to examine outcomes related to role functioning of young adults, and moderators of treatment acceptability and efficacy for this population. Perspective: Secondary analysis of data from 4 RCTs found an Internet-delivered psychological pain-management intervention acceptable and clinically efficacious for improving disability, anxiety, depression and pain intensity in young adults (18–30) with chronic pain. © 2024 United States Association for the Study of Pain, Inc.

Integrity signals

Registry

Crossref · 10.1016/j.jpain.2023.12.004

Cites

57 of 57 references verified0 citation errors · 0 not checkable

Statistics

Nothing to recompute.

Claims the paper makes

23 of 48 cited sources checked · 9 supported · 1 flagged · accuracy not yet measured

  • Premisecitation

    The one trial in chronic pain that examined age effects on attrition found higher attrition during follow-up for younger adults.

    “The 1 trial in chronic pain that has examined age effects on attrition 26 also found higher attrition during follow-up for younger adults.”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites [26] Herbert, 2017, Telehealth versus in-person acceptance and commitment therapy for chronic pain: a randomized noninferiority trial, J Pain source
  • Premisecitation

    Up to 40% of young adults with chronic pain that has persisted since childhood are not engaged with adult pain services.

    “Up to 40% of young adults with chronic pain that has persisted since childhood are not engaged with adult pain services, 15”
    Quote in the paperSubstantial claim1 of 1 sources checked
    • cites [15] Murray, 2022, Healthcare transition among young adults with childhood-onset chronic pain: a mixed methods study and proposed framework, J Pain source

      The Results (Healthcare transition) report that 41.8% of young adults with childhood-onset chronic pain were not engaged in adult-centered healthcare services for pain. This supports the substance of the claim, but 41.8% is slightly above the stated ceiling of “up to 40%." (LLM, conf=0.84)

      Experimental — accuracy not yet measured
  • Premisecitation

    Of 61 RCTs in recent reviews of psychological pain management, only 2 reported participants with a mean age between 18 and 30.

    “In fact, of the 61 RCTs in these reviews, only 2 reported participants with a mean age between 18 and 30.19,20”
    Quote in the paperSubstantial claim1 of 2 sources checked
    • cites [19] D'Souza, 2008, Relaxation training and written emotional disclosure for tension or migraine headaches: a randomized, controlled trial, Ann Behav Med source

      The Methods > Participants passage describes a randomized trial of undergraduate students with tension or migraine headaches, so this paper can serve as an example of a trial involving young adults. It does not report the tally of 61 RCTs or establish that only two had a mean participant age between 18 and 30; the passages retrieved also do not give this trial’s mean age. (LLM, conf=0.83)

      Experimental — accuracy not yet measured
    • cites [20] Feuille, 2015, Pain, mindfulness, and spirituality: a randomized controlled trial comparing effects of mindfulness and relaxation on pain-related outcomes in migraineurs, J Health Psychol source
  • Premisecitation

    Young adults with chronic pain report symptom invalidation and helplessness when consulting adult primary and specialty care providers due to their age.

    “However, likely unique to this emerging adult population, they report that due to their age, they experience symptom invalidation and helplessness when consulting adult primary and specialty care providers.6,8,14,15”
    Quote in the paperSubstantial claim2 of 4 sources checked
    • cites [6] Stinson, 2013, Understanding the information and service needs of young adults with chronic pain: perspectives of young adults and their providers, Clin J Pain source
    • cites [8] Brown, 2021, A scoping review of chronic pain in emerging adults, Pain Rep source

      The Results sections on barriers to health care and social interference report that emerging adults with chronic pain felt their illness was invalidated because of their age and described dependence on health care providers. The review does not specifically report helplessness or locate these experiences in consultations with adult primary and specialty care providers. Page numbers are not available in our copy. (LLM, conf=0.85)

      Experimental — accuracy not yet measured
    • cites [14] American Psychological Association, Emerging adults with chronic pain face stigma. Published 2013. Accessed 10 January, 2022. https://www.apa.org/gradpsych/2013/11/chronic-pain.

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

    • cites [15] Murray, 2022, Healthcare transition among young adults with childhood-onset chronic pain: a mixed methods study and proposed framework, J Pain source

      The Results (Healthcare transition; page unavailable) report that young adults perceived adult providers as invalidating and described disappointment and hopelessness after repeated attempts to find one who would not dismiss their pain. The paper does not say that providers invalidated their symptoms because of their age. Its quantitative results list primary and specialty care as services used, but do not establish that the reported invalidation occurred in both settings. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
  • Premisecitation

    Age effects in Internet-delivered mental health treatment engagement and completion rates have been found, particularly when these interventions are offered as part of routine care.

    “Age effects in Internet-delivered mental health treatment engagement and completion rates also being found, particularly when these interventions are offered as part of routine care.22,52”
    Quote in the paperSubstantial claim2 of 2 sources checked
    • cites [22] Cross, 2022, Factors associated with treatment uptake, completion, and subsequent symptom improvement in a national digital mental health service, Internet Interventions source
    • cites [52] Mewton, 2013, A naturalistic study of the acceptability and effectiveness of internet-delivered cognitive behavioural therapy for psychiatric disorders in older Australians, PLoS One source
  • Classified as probably not a substantial claim. 21
  • May combine two claims. 56
  • The quote only partly states this claim. 1
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    The reference group of average-age participants (aged 39-63 years) consisted of 561 participants (81% female), which was 42% of the total sample.

    “This resulted in a subsample of n = 561 (81% female), which was 42% of the total sample”
    Quote in the paperNot a substantial claim1 of 3 sources checked
    • cites [31] Dear, 2017, The pain course: a randomised controlled trial comparing a remote-delivered chronic pain management program when provided in online and workbook formats, Pain source
    • cites [32] Dear, 2013, The Pain Course: a randomised controlled trial of a clinician-guided Internet-delivered cognitive behaviour therapy program for managing chronic pain and emotional well-being, Pain source
    • cites [33] Dear, 2015, The Pain Course: a randomised controlled trial examining an internet-delivered pain management program when provided with different levels of clinician support, Pain source

      The Methods (section 2.1, page unavailable) state that 490 participants met the trial’s inclusion criteria, with 614 people applying. A subsample of 561 therefore cannot be 42% of this paper’s participant sample; the cited passages also do not identify an average-age reference group aged 39–63. (LLM, conf=0.87)

      Checked by a reasoning model — may be wrong.

      Experimental — accuracy not yet measured
  • May combine two claims.

    Premisecitation

    In recent reviews of psychological pain management for adults with chronic pain and migraine, mean ages were 50 and 39 years, respectively.

    “The mean ages in recently published reviews for psychological pain management in adults with chronic pain 16 and migraine 18 were 50-and 39 years, respectively.”
    Quote in the paperSubstantial claim1 of 2 sources checked
    • cites [16] Williams, 2020, Psychological therapies for the management of chronic pain (excluding headache) in adults, Cochrane Database Syst Rev source
    • cites [18] Sharpe, 2019, Psychological therapies for the prevention of migraine in adults, Cochrane Database Syst Rev source
  • May combine two claims.

    Premisecitation

    Young adults with chronic pain frequently report difficulties seeking out and accessing treatment and can wait months to years for specialist pain management care.

    “Similar to adults of all ages, young adults with chronic pain frequently report difficulties seeking out and accessing treatment, 6 and can wait months to years for specialist pain management care.12,13”
    Quote in the paperSubstantial claim1 of 3 sources checked
    • cites [6] Stinson, 2013, Understanding the information and service needs of young adults with chronic pain: perspectives of young adults and their providers, Clin J Pain source
    • cites [12] Higginson, 2019, Moving on: transition experiences of young adults with chronic pain, Can J Pain source

      The Results (Collaborative systems: The bridge; page unavailable) describe a participant who was still waiting to be seen at an adult chronic pain clinic three years after joining its waiting list. This supports the possibility of a years-long wait for specialist care, but our copy does not establish the claimed months-to-years range. The separate claim about frequently reported access difficulties carries citation 6, not this source’s citation. (LLM, conf=0.82)

      Experimental — accuracy not yet measured
    • cites [13] Hogg, 2012, Waiting in pain: a systematic investigation into the provision of persistent pain services in Australia, Med J Aust source
  • May combine two claims.

    Premisecitation

    Younger adults are less likely to complete treatment than older adults; a recent study showed young adults had 15% lower completion rates than adults over 30.

    “They are also less likely to complete treatment than older adults, 24,25 with a recent study showing young adults had 15% lower completion rates than adults over 30.22”
    Quote in the paperSubstantial claim1 of 3 sources checked
    • cites [24] Wang, 2007, Unmet need for services and interventions among adolescents with mental disorders, Am J Psychiatry source
    • cites [25] Edlund, 2002, Dropping out of mental health treatment: patterns and predictors among epidemiological survey respondents in the United States and Ontario, Am J Psychiatry source
    • cites [22] Cross, 2022, Factors associated with treatment uptake, completion, and subsequent symptom improvement in a national digital mental health service, Internet Interventions source

      Table 2 in Results > Univariate analyses shows lower treatment completion among younger patients: 54.8% for ages 18–24 and 61% for ages 25–35, versus 68.3% for ages 35–45. It does not compare young adults with a single over-30 group or report a 15% lower completion rate, so the specific figure and cutoff are not supported. (LLM, conf=0.86)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Study design and conductown data

    Clinical improvements were comparable within the treatment conditions of RCT2 and RCT3, so the treatment conditions were considered equal and amalgamated into one Treatment group per RCT.

    “Analyses showed clinical improvements were comparable within the treatment conditions of both RCTs.Accordingly, the treatment conditions were considered equal and amalgamated into one 'Treatment' group per RCT for the purpose of this study and previously published studies.41,42”
    Quote in the paperSubstantial claim1 of 2 sources checked
    • cites [41] Bisby, 2023, Can internet-delivered pain management programs reduce psychological distress in chronic pain? Exploring relationships between anxiety and depression, pain intensity, and disability, Pain Med source
    • cites [42] Bisby, 2023, The timing and magnitude of improvements in depression, anxiety, disability, and pain intensity during an internet-delivered program for chronic pain, J Pain source

      The Participants section (page unavailable) says treatment participants from three prior RCTs received the same course and were collapsed into a single sample. The Conclusions section reports no significant difference in the timing of depression and anxiety improvement across guidance conditions. The paper does not say that conditions within RCT2 and RCT3 were deemed equal and amalgamated into one Treatment group per RCT, or that this was done in previously published studies. (LLM, conf=0.84)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Interpretationcitation

    The significant improvements across outcomes seen in young adults were comparable to those seen in the average-age adult reference group who completed the same pain-management intervention and are consistent with improvements seen in the broader adult population.

    “The significant improvements across outcomes seen in young adults were also comparable to those seen in the average-age adult reference group who completed the same pain-management intervention and are consistent with improvements seen in the broader adult population.16,17”
    Quote in the paperSubstantial claim1 of 2 sources checked
    • cites [16] Williams, 2020, Psychological therapies for the management of chronic pain (excluding headache) in adults, Cochrane Database Syst Rev source

      Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.

      Experimental — accuracy not yet measured
    • cites [17] Gandy, 2022, Internet-delivered cognitive and behavioural based interventions for adults with chronic pain: a systematic review and meta-analysis of randomized controlled trials, Pain source
  • May combine two claims.

    Interpretationcitation

    The proportion of young adults accessing psychological care (33%) is higher than previous findings in North America (19%), possibly due to how individual and group mental healthcare is partially subsidised by the government in Australia.

    “The proportion of young adults accessing psychological care is higher than previous findings in North America (33% vs 19%), 15 possibly due to how individual and group mental healthcare is partially subsidised by the government in Australia.53”
    Quote in the paperNot a substantial claim1 of 2 sources checked
    • cites [15] Murray, 2022, Healthcare transition among young adults with childhood-onset chronic pain: a mixed methods study and proposed framework, J Pain source
    • cites [53] Australian Government, Better Access fact sheet – professionals. Department of Health and Aged Care Australia 2019.

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Premisecitation

    In 2 studies that assessed treatment feasibility across adult age groups, uptake and completion increased by age, with significant differences between young and older adults over 60.

    “For example, in 2 studies that assessed treatment feasibility across adult age groups, uptake 22 and completion 22,52 increased by age, with significant differences between young and older adults over 60.”
    Quote in the paperSubstantial claim2 of 2 sources checked
    • cites [22] Cross, 2022, Factors associated with treatment uptake, completion, and subsequent symptom improvement in a national digital mental health service, Internet Interventions source
    • cites [52] Mewton, 2013, A naturalistic study of the acceptability and effectiveness of internet-delivered cognitive behavioural therapy for psychiatric disorders in older Australians, PLoS One source

      The Abstract Results and Discussion say older adults were more likely than younger adults to complete the six iCBT lessons, supporting the completion finding attributed to this paper. The Methods describe tests for significant differences between age groups, but the retrieved passages do not report a statistically significant young-versus-over-60 completion difference. The citing sentence assigns its separate uptake finding to reference 22, not this paper. (LLM, conf=0.78)

      Experimental — accuracy not yet measured
  • May combine two claims.

    Study design and conductcitation

    The Patient Health Questionnaire 9-Item measure has been shown to be reliable and valid, and its internal consistency in the current study was good (α = .78).

    “The measure has been shown to be both reliable and valid, 38 and internal consistency in the current study was good (α = .78).”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [38] Kroenke, 2001, The PHQ-9: validity of a brief depression severity measure, J Gen Intern Med source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    The percentage of participants reporting improvements of ≥30% and ≥50% was reported based on IMMPACT recommendations.

    “Based on the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials recommendations, 48 the percentage of participants reporting improvements in symptoms of ≥30% and ≥50% from pre-to posttreatment for both groups and pre-treatment to follow-up for the treatment group are reported.”
    Quote in the paperNot a substantial claim1 of 1 sources checked
    • cites [48] Smith, 2020, Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations, Pain source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    Over the 8 weeks before applying, the number of visits to any healthcare service ranged from 1 to 21.

    “Over the eight weeks, the number of visits to any healthcare service ranged from 1 to 21.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    The young adult sample was predominantly female (90%).

    “was predominately female (90%)”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The treatment group had significant percent improvements in anxiety (95% CI: 13%, 36%) and depression (95% CI: 18%, 35%) but the control group did not (anxiety: -18%, 17%; depression: -11%, 16).

    “Significant percent improvements in anxiety and depression symptoms were also found for the treatment group (95% CIs anxiety: 13%, 36%; depression: 18%, 35%) but not the control group (95% CIs anxiety: -18%, 17%; depression: -11%, 16).”
    Quote in the paperSubstantial claim
  • May combine two claims. The quote only partly states this claim.

    Findingown data

    At follow-up, there was no main effect of Time, indicating treatment improvements in disability were maintained at 3 months for the treatment group (P = .25), with percentage improvements (95% CI: 10%, 37%).

    “At follow-up, we found no main effect of Time, indicating treatment improvements were maintained at 3-months for the treatment group (P = .25),with percentage improvements in PDI symptoms supporting this (95% CI: 10%, 37%).”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    For the treatment group, there was no significant effect of Time from post-treatment to follow-up for pain intensity, suggesting improvements were maintained (P = .34).

    “For the treatment group, there was no significant effect of Time from post-treatment to follow-up, suggesting improvements were maintained (P = .34).”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    For anxiety and depression, GEE analyses showed significant Group-by-time interactions at post-treatment (anxiety: P < .001, d = .54; depression: P < .001, d = .67), with larger pre-post improvements in both for the treatment group compared to control.

    “For anxiety and depression symptoms, GEE analyses showed significant Group-by-time interactions at posttreatment (anxiety: P < .001,d = .54;depression: P < .001,d = .67),with estimated marginal means revealing larger pre-post-treatment improvements in both anxiety and depression symptoms for the treatment group, compared to the control.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    Average pain duration in the young adult sample was just under 7 years (range: 6 months to 21 years).

    “Average pain duration was just under 7 years (range: 6 months to 21 years).”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    42% of the young adult sample first experienced chronic pain as a child or adolescent (prior to age 18).

    “Forty-two percent of the sample (n = 64) indicated they first experienced chronic pain as a child or adolescent (ie, prior to age 18).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The treatment group had significant percent improvements in pain intensity (95% CI: 6%, 21%) but the control group did not (95% CI: -7%, 12%).

    “Significant percent improvements were also found for the treatment group (95% CI: 6%, 21%), but not control (95% CI: -7%, 12%).”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    A third of young adults had seen a psychologist for pain in the 8 weeks before applying.

    “with a third reporting they had seen a psychologist.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    88% of young adults had seen their general medical practitioner for pain in the 8 weeks before applying.

    “Most participants had seen their general medical practitioner (88%)”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Findingown data

    The most common pain area reported was the back (76%), followed by the leg/foot (61%).

    “The most common pain area reported was the back (76%), followed by the leg/foot (61%).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The number of participants experiencing clinically meaningful improvements of ≥30% and ≥50% on the GAD-7 and PHQ-9 was significantly greater in the treatment group than the control group (anxiety 30%: P < .001, 50%: P = .01; depression 30%: P < .001, 50%: P < .001).

    “The number of participants experiencing clinically meaningful improvements of ≥30% and ≥50% on the GAD7 and PHQ9 were significantly greater in the treatment group, compared to the control group (anxiety 30%, 50%: P < .001,P = .01;depression 30%, 50%: P < .001,P < .001,respectively).”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    The number of participants with PDI scores improving by ≥30% and ≥50% was significantly greater in the treatment group than the control group at post-treatment (30%: P < .001; 50%: P < .001).

    “Regarding clinical significance, the number of participants with scores on the PDI improving by ≥30% and ≥50% was significantly greater in the treatment group, than the control group at post-treatment (30%: P < .001;50%: P < .001).”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    For pain-related disability, GEE analyses revealed a significant Group by Time interaction at post-treatment (P = .002, d = .68), with the treatment group showing larger pre-post improvements than controls.

    “Regarding pain-related disability, GEE analyses revealed a significant Group by Time interaction at posttreatment (P = .002,d = .68).Estimated marginal means showed the treatment group had larger pre-posttreatment improvements in disability, compared to controls.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    The treatment group had significant percent improvements in disability symptoms (95% CI: 7%, 30%) but the control group did not (95% CI: -9%, 13%).

    “Significant percent improvements in disability symptoms were also found for the treatment group (95% CI: 7%, 30%) but not the control group (95% CI: -9%, 13%).”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    88% of the young adult sample reported pain in more than one location.

    “The number of pain locations ranged from 1 to 10 or more, with 88% of the sample reporting pain in more than one location.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The rate of participants experiencing ≥30% and ≥50% clinical improvements at follow-up remained stable from post-treatment for anxiety (30%: P = .51; 50%: P = .08) and depression (30%: P = .45; 50%: P = .54).

    “The rate of participants experiencing ≥30% and ≥50% clinical improvements at follow-up also remained stable from post-treatment for both anxiety (30%: P = .51;50%: P = .08)and depression (30%: P = .45;50%: P = .54).”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    70% of the young adult sample reported currently taking medication for pain at the time of application to the research trial.

    “Most participants (70%) reported they were currently taking medication for pain at the time of application to the research trial”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    38% of the young adult sample reported taking medication for their mental health.

    “and 38% reported they were taking medication for their mental health.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    78% (n = 119) of all participants completed at least 4 lessons and were deemed to have adhered.

    “and 78% (n = 119) completed at least 4 lessons and were deemed to have adhered.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    The young adult sample had a mean age of 25.8 years (SD = 3.2 years; range 18-30 years).

    “Overall, the sample had a mean age of 25.8 years (SD = 3.2 years; range 18-30 years)”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    For pain intensity, GEE analyses showed a significant Group by Time interaction at post-treatment (P = .005, d = .41), with the treatment group showing larger pre-post improvements than control.

    “GEE analyses for pain intensity showed a significant Group by Time interaction at post-treatment (P = .005,d = .41).Estimated marginal means showed the treatment group had larger pre-post-treatment improvements in pain intensity, compared to the control.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    The highest median number of visits to any service was 3 (physiotherapist or osteopath), with a median of 2 for most other services.

    “The highest median number of visits to any service was 3 (physiotherapist or osteopath), with a median number of visits of 2 for most other services (general practitioner, nurse, psychologist, counsellor/social worker, 'other health service').”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Findingown data

    58% of young adults had seen a medical specialist for pain in the 8 weeks before applying.

    “and/or a medical specialist (58%)”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The treatment group had clinically meaningful reductions in symptoms for all outcomes, and these were maintained at follow-up.

    “The treatment group also had clinically meaningful reductions in symptoms for all outcomes, with these maintained at follow-up.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    Post-treatment improvements were equivalent for young-adult and average-aged adult treatment groups, with no significant differences in feasibility or acceptability outcomes.

    “Post-treatment improvements were equivalent for young-adult and average-aged adult treatment groups, with no significant differences in feasibility or acceptability outcomes.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    A meaningful proportion of participants did not complete treatment; over one-third of young adults did not access the final lesson.

    “While we found no age effects between our 2 samples, it is important to note that a meaningful proportion of participants did not complete treatment.For example, over one-third of young adults did not access the final lesson.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    There was a significant Group by Time interaction for disability, and a posthoc comparison found no differences in demographics or baseline clinical outcome variables between participants who completed the PDI and those who did not.

    “However, we found a significant Group by Time interaction for disability, and a posthoc comparison found no differences in demographics or baseline clinical outcome variables between participants who completed the PDI and those who did not (see Table S2 in Supplementary Material).”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    At follow-up, there was a main effect of Time for the reference group indicating pain intensity further improved (P = .02), and it was maintained for the young-adult group (P = .22).

    “We found a main effect of Time at follow-up for the reference group, indicating pain intensity further improved for this group (P = .02),and was maintained for the young-adult group (P = .22).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The young-adult group had higher depression symptoms than the average-age group at pre-treatment (P = .05), post-treatment (P = .01), and follow-up (P = .04).

    “and depression symptoms (pre: P = .05;post: P = .01;f/u: P = .04).”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    In the reference group, 96% (n=541) engaged in treatment, 84% (n=472) adhered, and the non-completion rate was 26% (n=146).

    “Of this group, 96% (n = 541) engaged in the treatment, and 84% (n = 472) adhered.The non-completion rate was 26% (n = 146).”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    In the current study, 37%, 25%, 52%, and 47% of young adults made clinical improvements (≥30% improvements) in disability, pain intensity, depression, and anxiety, respectively, immediately post-treatment.

    “For example, in the current study 37%, 25%, 52%, and 47% of young adults were found to make clinical improvements (defined as ≥30% improvements) in disability, pain intensity, depression and anxiety, respectively, immediately post-treatment.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    In the control group, 7%, 10%, 15%, and 17% made such improvements in disability, pain intensity, depression, and anxiety, respectively.

    “This compared with 7%, 10%, 15%, and 17% making such improvements in disability, pain intensity, depression and anxiety, respectively, in the control group.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    The treatment group significantly improved in disability, pain intensity, anxiety symptoms, and depression symptoms post-treatment compared to the control group.

    “In line with our expectations, the treatment group significantly improved in disability, pain intensity, anxiety symptoms and depression symptoms post-treatment, compared to the control group.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingnone given

    Treatment engagement was high; however, around one third of participants did not complete the intervention.

    “Treatment engagement was high; however, around one third of participants did not complete the intervention.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The young-adult group had higher anxiety symptoms than the average-age group at pre-treatment (P = .001), post-treatment (P = .001), and follow-up (P = .01).

    “Estimated marginal means at each timepoint revealed the young-adult group had higher anxiety symptoms (pre: P = .001;post: P = .001;f/u: P = .01)”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    The treatment was deemed acceptable, with most participants endorsing they would recommend it to others with chronic pain.

    “The treatment was deemed acceptable; with most endorsing they would recommend it to others with chronic pain.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingown data

    There were no significant differences between the young-adult and average-age participant groups on engagement, adherence, completion, satisfaction, perceived worth of time, or recommendation of the programme.

    “Chi-square analyses indicated no significant differences between the young and averageage participant groups on engagement (χ 2 = .91,P = .34),adherence (χ 2 = 2.88, P = .09),or completion (χ 2 = 3.39, P = .07).”
    • Also stated in: § Examining Age Effects on Outcomes · plain
      “Chi-square analyses indicated no significant differences between the groups on satisfaction (χ 2 = .54,P = .46),time (χ 2 = .00,P = .98),or recommendation (χ 2 = .18,P = .67).”
    • Also stated in: § Discussion · plain
      “Regarding feasibility and acceptability, there were no differences between our young adult and average adult samples in rates of engagement, adherence, completion, or in treatment satisfaction.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    In the current study, 95%, 78%, 66%, and 85% of younger adults engaged, adhered, completed, and reported being satisfied with the treatment, respectively.

    “In the current study, 95%, 78%, 66%, and 85% of younger adults were found to engage, adhere, complete and report being satisfied with the treatment, respectively.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Findingown data

    Two thirds of participants deteriorated on one outcome, and the remaining third deteriorated across 2 outcomes.

    “Two thirds of participants deteriorated on one outcome, with the remaining third deteriorating across 2.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Findingnone given

    The intervention was found to be acceptable and engagement levels were high.

    “The intervention was found to be acceptable and engagement levels were high.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductown data

    The four source RCTs were pre-registered on the Australian New Zealand Clinical Trials Registry.

    “RCTs were pre-registered on the Australian New Zealand Clinical Trials Registry (ACTRN12611000894998; ACTRN12613000252718; ACTRN12614000768695; ACTRN12615001003561).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites ACTRN12611000894998; ACTRN12613000252718; ACTRN12614000768695; ACTRN12615001003561

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Study design and conductnone given

    The current study deviated from its protocol by reversing the aims and by conducting analyses comparing the young-adult sample with a second sample of adults from the four RCTs.

    “We deviated from the protocol in the following ways: 1) the aims of the study are reversed, and we present the feasibility aim prior to clinical efficacy, and 2) we conducted analyses comparing our young-adult sample with a second sample of adults taken from the 4 RCTs.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Premisecitation

    Less than a fifth of young adults with chronic pain surveyed were receiving psychological support, although psychological intervention remains a recommended first-line treatment.

    “although psychological intervention remains a recommended first-line treatment, a recent study found that less than a fifth of young adults surveyed were receiving psychological support. 2”
    Quote in the paperSubstantial claim0 of 1 sources checked
    • cites [2] Murray, 2022, The prevalence of chronic pain in young adults: a systematic review and meta-analysis, Pain source
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Study design and conductcitation

    A protocol for the current study, with a data-analysis plan, was pre-registered on OSF in May 2022.

    “A protocol for the current study, with a data-analysis plan, was pre-registered on OSF in May 2022 (https://doi.org/10.17605/OSF.IO/84YJQ).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites https://doi.org/10.17605/OSF.IO/84YJQ

      Couldn’t be matched to a paper in Crossref, so it can’t be checked.

  • May combine two claims.

    Interpretationown data

    The treatment group significantly improved across all outcomes compared with control, with improvements maintained at follow-up.

    “The treatment group significant improved across all outcomes, compared with control, with improvements maintained at follow-up.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Interpretationreasoning

    The intervention's features (online, free, available throughout the country, transdiagnostic, limited exclusions) increase the representativeness of the sample and its applicability in the real world.

    “These features increase the representativeness of the sample, and thus its applicability in the real world.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Study design and conductcitation

    The Pain Disability Inventory has sound psychometric properties, and its internal consistency in the current study was good (α = .86).

    “The PDI has been shown to have sound psychometric properties, 36 and the internal consistency of the items in the current study was good (α = .86).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [36] Tait, 1987, The Pain Disability Index: psychometric and validity data, Arch Phys Med Rehabil

      Not checked in the free run.

  • May combine two claims.

    Interpretationown data

    Young adults had high engagement and acceptability ratings, though 34% did not complete the intervention.

    “Young adults had high engagement and acceptability ratings, though 34% did not complete the intervention.”
    Quote in the paperSubstantial claim
  • Classified as probably not a substantial claim. May combine two claims.

    Interpretationreasoning

    The absence of significant differences in the current study is unexpected, and caution is needed in drawing firm conclusions.

    “Hence, the absence of significant differences in the current study is unexpected, and some caution is arguably needed in drawing firm conclusions just yet.”
    Quote in the paperSubstantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing).

    Premisecitation

    Numerical rating scales are recommended for assessing pain intensity.

    “Numerical ratings scales are recommended for assessing pain intensity.40”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [40] Turk, 2003, Core outcome domains for chronic pain clinical trials: IMMPACT recommendations, Pain source
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Study design and conductcitation

    The Generalised Anxiety Disorder 7-Item measure has been shown to be reliable and valid for a range of anxiety disorders, and its internal consistency in the current study was excellent (α = .90).

    “The measure has been shown to be both reliable and valid for a range of anxiety disorders, 37 and internal consistency in the current study was excellent (α = .90).”
    Quote in the paperNot a substantial claim0 of 1 sources checked
    • cites [37] Spitzer, 2006, A brief measure for assessing generalized anxiety disorder: the GAD-7, Arch Intern Med source
  • May combine two claims.

    Interpretationown data

    Young adults can engage with and show improvements following a psychological pain-management intervention designed for all adults with chronic pain.

    “Findings indicate young adults can engage with and show improvements following a psychological pain-management intervention designed for all adults with chronic pain.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Interpretationown data

    An Internet-delivered psychological pain-management intervention is acceptable and clinically efficacious for improving disability, anxiety, depression, and pain intensity in young adults (18-30) with chronic pain.

    “Secondary analysis of data from 4 RCTs found an Internet-delivered psychological pain-management intervention acceptable and clinically efficacious for improving disability, anxiety, depression and pain intensity in young adults (18-30) with chronic pain.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Study design and conductreasoning

    We are unable to conduct longer term evaluations of treatment efficacy and are uncertain whether the maintained improvements at 3-months follow-up are a result of the intervention or other non-treatment related factors such as increased healthcare or medication usage, or natural remission.

    “We are therefore unable to conduct longer term evaluations of treatment efficacy and are uncertain whether the maintained improvements at 3-months follow-up are a result of the intervention or other non-treatment related factors such as increased healthcare or medication usage, or natural remission.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Study design and conductreasoning

    The content of the course included adults of all ages, and outcomes were not specific to the young-adult population.

    “Finally, the content of the course (eg, case stories, examples) included adults of all ages and outcomes were not specific to our population.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Interpretationown data

    Using pre-existing data allowed us to answer our research questions and determine that broad adult content was largely acceptable and efficacious for young adults.

    “Using pre-exiting data allowed us to answer our research questions and determine that broad adult content was largely acceptable and efficacious for young adults.”
    Quote in the paperSubstantial claim
  • May combine two claims.

    Study design and conductown data

    We were unable to report on the race, ethnicity, or gender identity of participants, so we cannot be certain how representative our sample was of emerging adults, nor whether findings would translate to all young people.

    “We were unable to report on the race, ethnicity, or gender identity of participants as this information was not initially captured.Thus, we cannot be certain how representative our sample was of emerging adults, nor whether findings would translate to all young people.”
    Quote in the paperNot a substantial claim
  • Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.

    Study design and conductnone given

    We were unable to assess whether the pattern of findings was impacted by trial cohort, or whether there were any moderators or predictors of treatment efficacy.

    “Third, we were unable to assess whether the pattern of findings was impacted by trial cohort, or whether there were any moderators or predictors of treatment efficacy.”
    Quote in the paperNot a substantial claim
  • May combine two claims.

    Interpretationown data

    Good clinical outcomes were observed at post-treatment and follow-up and were comparable to outcomes from a broader adult population.

    “Good clinical outcomes were observed at post-treatment and follow-up and were comparable to outcomes from a broader adult population.”
    Quote in the paperSubstantial claim
71 of 71
  • The paper relies on this without support.

    This is one of the first studies to assess the efficacy of a psychological pain-management programme in young adults with chronic pain.

    “This is one of the first studies to assess the efficacy of a psychological pain-management programme in young adults with chronic pain.”
  • The paper relies on this without support.

    Psychological management is a first-line treatment for chronic pain, young adults report difficulties accessing appropriate pain services, and very few studies have investigated how this emerging adult population responds to psychological intervention.

    “While psychological management is a first-line treatment for chronic pain, young adults report difficulties with accessing appropriate pain services and very few studies have investigated how this emerging adult population responds to psychological intervention.”
  • The paper relies on this without support.

    The final lesson or module of most Internet-delivered pain management interventions typically focuses on helping people think about and develop plans for managing pain over the longer term, covering issues like lapse management.

    “The final lesson or module of most Internet-delivered pain management interventions typically focus on helping people think about and develop plans for managing pain over the longer term, covering issues like lapse management.”
3 of 3

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

  • High-school-diploma percentage is too high

    Minor

    The reported 33 participants are 21.7% of the overall sample of 152, rather than 48%.

    Reported 48 · recomputed 21.710526

  • Some-high-school percentage is too high

    Minor

    The table lists 15 of 152 participants in this education category, which is 9.9%, not 18%.

    Reported 18 · recomputed 9.868421

  • Young-adult satisfaction percentage does not match the stated respondents

    Minor

    Among the 131 participants who completed the questionnaire, 118 satisfied participants represent 90.1%, not 85%.

    Reported 85 · recomputed 90.076336

3 of 3

Cites

Flagged first, then by citations

Cited by

Sorted by citations

Authors
Dudeney, J., Scott, A. J., Hathway, T., Bisby, M. A., Harte, N., Titov, N., & Dear, B. F.
Affiliations
Macquarie University (AU)
Venue
The Journal of Pain
Publisher
Elsevier BV
Published
2024-06
Volume
25
Issue
6
Pages
104447
ISSN
1526-5900 (ISSN-L)
OpenAlex
W4389903794
Cited by
9
References
54
Citations by year
2026: 5 · 2025: 2 · 2024: 2
FWCI
2.32
Type
journal article
Language
en
Open access
Locations
  • Journal of Pain (publishedVersion)
  • PubMed (publishedVersion)
Funders
Macquarie University (EES2022, MQRF0001007)
Topics
  • Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
  • Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
Keywords
online intervention, psychological pain management, chronic pain, young adults, feasibility, acceptability, treatment engagement, medication adherence, pain intensity, disability, anxiety, depression
MeSH terms
Internet-Based Intervention, Adolescent, Adult, Anxiety, Feasibility Studies, Female, Humans, Male, Patient Acceptance of Health Care, Telemedicine, Internet, Young Adult, Chronic Pain, Pain Management

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-11.

Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-11.

Cited sources are checked by gpt-6-sol.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

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