Internet-Delivered Psychological Pain-Management for Young Adults With Chronic Pain: An Investigation of Clinical Trial Data
Open accessAbstract
Young adults report chronic pain at rates of around 12% but lack access to clinical services. There is interest in learning how this emerging adult population engages with and responds to treatment. Using data from young adults aged 18 to 30 years (Mage = 25.8, SD = 3.2), taken from 4 previous randomised controlled trials, the current study investigated the feasibility, acceptability, and efficacy of an internet-delivered psychological pain-management intervention for young adults with chronic pain. We compared young adults in a treatment group (n = 104) with 1) a young-adult wait-list control group (n = 48), and 2) a treatment group reflecting the average-aged participant from the previous trials (39–63 years, n = 561). Feasibility was determined through treatment engagement, adherence and completion, and acceptability through a treatment satisfaction measure. Clinical outcomes were disability, pain intensity, anxiety, and depression; assessed at pre-treatment, post-treatment, and 3-month follow-up. Generalised estimation equation analyses were undertaken, using multiple imputations to account for missing data. Young adults had high engagement and acceptability ratings, though 34% did not complete the intervention. The treatment group significant improved across all outcomes, compared with control, with improvements maintained at follow-up. Post-treatment improvements were equivalent for young-adult and average-aged adult treatment groups, with no significant differences in feasibility or acceptability outcomes. Findings indicate young adults can engage with and show improvements following a psychological pain-management intervention designed for all adults with chronic pain. Future research is encouraged to examine outcomes related to role functioning of young adults, and moderators of treatment acceptability and efficacy for this population. Perspective: Secondary analysis of data from 4 RCTs found an Internet-delivered psychological pain-management intervention acceptable and clinically efficacious for improving disability, anxiety, depression and pain intensity in young adults (18–30) with chronic pain. © 2024 United States Association for the Study of Pain, Inc.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
23 of 48 cited sources checked · 9 supported · 1 flagged · accuracy not yet measured
- Premisecitation
The one trial in chronic pain that examined age effects on attrition found higher attrition during follow-up for younger adults.
“The 1 trial in chronic pain that has examined age effects on attrition 26 also found higher attrition during follow-up for younger adults.”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [26] Herbert, 2017, Telehealth versus in-person acceptance and commitment therapy for chronic pain: a randomized noninferiority trial, J Pain source
- Premisecitation
Up to 40% of young adults with chronic pain that has persisted since childhood are not engaged with adult pain services.
“Up to 40% of young adults with chronic pain that has persisted since childhood are not engaged with adult pain services, 15”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [15] Murray, 2022, Healthcare transition among young adults with childhood-onset chronic pain: a mixed methods study and proposed framework, J Pain source
The Results (Healthcare transition) report that 41.8% of young adults with childhood-onset chronic pain were not engaged in adult-centered healthcare services for pain. This supports the substance of the claim, but 41.8% is slightly above the stated ceiling of “up to 40%." (LLM, conf=0.84)
Experimental — accuracy not yet measured
- Premisecitation
Of 61 RCTs in recent reviews of psychological pain management, only 2 reported participants with a mean age between 18 and 30.
“In fact, of the 61 RCTs in these reviews, only 2 reported participants with a mean age between 18 and 30.19,20”
Quote in the paperSubstantial claim1 of 2 sources checked- cites [19] D'Souza, 2008, Relaxation training and written emotional disclosure for tension or migraine headaches: a randomized, controlled trial, Ann Behav Med source
The Methods > Participants passage describes a randomized trial of undergraduate students with tension or migraine headaches, so this paper can serve as an example of a trial involving young adults. It does not report the tally of 61 RCTs or establish that only two had a mean participant age between 18 and 30; the passages retrieved also do not give this trial’s mean age. (LLM, conf=0.83)
Experimental — accuracy not yet measured - cites [20] Feuille, 2015, Pain, mindfulness, and spirituality: a randomized controlled trial comparing effects of mindfulness and relaxation on pain-related outcomes in migraineurs, J Health Psychol source
- Premisecitation
Young adults with chronic pain report symptom invalidation and helplessness when consulting adult primary and specialty care providers due to their age.
“However, likely unique to this emerging adult population, they report that due to their age, they experience symptom invalidation and helplessness when consulting adult primary and specialty care providers.6,8,14,15”
Quote in the paperSubstantial claim2 of 4 sources checked- cites [6] Stinson, 2013, Understanding the information and service needs of young adults with chronic pain: perspectives of young adults and their providers, Clin J Pain source
- cites [8] Brown, 2021, A scoping review of chronic pain in emerging adults, Pain Rep source
The Results sections on barriers to health care and social interference report that emerging adults with chronic pain felt their illness was invalidated because of their age and described dependence on health care providers. The review does not specifically report helplessness or locate these experiences in consultations with adult primary and specialty care providers. Page numbers are not available in our copy. (LLM, conf=0.85)
Experimental — accuracy not yet measured - cites [14] American Psychological Association, Emerging adults with chronic pain face stigma. Published 2013. Accessed 10 January, 2022. https://www.apa.org/gradpsych/2013/11/chronic-pain.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites [15] Murray, 2022, Healthcare transition among young adults with childhood-onset chronic pain: a mixed methods study and proposed framework, J Pain source
The Results (Healthcare transition; page unavailable) report that young adults perceived adult providers as invalidating and described disappointment and hopelessness after repeated attempts to find one who would not dismiss their pain. The paper does not say that providers invalidated their symptoms because of their age. Its quantitative results list primary and specialty care as services used, but do not establish that the reported invalidation occurred in both settings. (LLM, conf=0.86)
Experimental — accuracy not yet measured
- Premisecitation
Age effects in Internet-delivered mental health treatment engagement and completion rates have been found, particularly when these interventions are offered as part of routine care.
“Age effects in Internet-delivered mental health treatment engagement and completion rates also being found, particularly when these interventions are offered as part of routine care.22,52”
Quote in the paperSubstantial claim2 of 2 sources checked- cites [22] Cross, 2022, Factors associated with treatment uptake, completion, and subsequent symptom improvement in a national digital mental health service, Internet Interventions source
- cites [52] Mewton, 2013, A naturalistic study of the acceptability and effectiveness of internet-delivered cognitive behavioural therapy for psychiatric disorders in older Australians, PLoS One source
- Interpretationown data
The post- and follow-up treatment effects expand on findings of psychological pain-management for young adults by showing significant effects of a cognitive and behavioural approach in young adults with heterogeneous pain conditions, recruited from around the country.
“The post-and follow-up treatment effects expand on findings of psychological painmanagement for young adults, 19 by showing significant effects of a cognitive and behavioural approach in young adults with heterogeneous pain conditions, recruited from around the country.”
Quote in the paperSubstantial claim1 of 1 sources checked- cites [19] D'Souza, 2008, Relaxation training and written emotional disclosure for tension or migraine headaches: a randomized, controlled trial, Ann Behav Med source
- Interpretationcitation
Internet-delivered psychological pain-management provides a solution to some of the barriers to accessing appropriate care reported by young adults, such as lack of services and negative experiences with in-person care.
“Internet-delivered psychological pain-management provides a solution to some of the barriers to accessing appropriate care reported by young adults, such as lack of services and negative experiences with in-person care.8,12”
Quote in the paperSubstantial claim2 of 2 sources checked- cites [8] Brown, 2021, A scoping review of chronic pain in emerging adults, Pain Rep source
The Results (§3.6.5) describe difficulty accessing specialized treatment and negative experiences of care, while the Discussion (§4.1) suggests that more online treatment options could better meet emerging adults’ needs. The review does not establish that internet-delivered psychological pain management provides a solution to those barriers specifically. (LLM, conf=0.84)
Experimental — accuracy not yet measured - cites [12] Higginson, 2019, Moving on: transition experiences of young adults with chronic pain, Can J Pain source
The Results (Collaborative systems: The bridge) describe young adults unable to access adult pain services and one participant's harmful experience with in-person pain management; the Discussion also identifies a shortage of chronic pain clinics. The paper does not say that internet-delivered psychological pain management would address these barriers. (LLM, conf=0.86)
Experimental — accuracy not yet measured
- Study design and conductcitation
Multiple imputation was used to handle missing data, accounting for participants' baseline symptom severity, group, and number of lessons completed.
“Consistent with intentionto-treat recommendations 43 and research into missing data in Internet-delivered interventions, 44,45 we used multiple imputation to handle missing data, accounting for participants baseline symptom severity, group, and number of lessons completed.45”
Quote in the paperSubstantial claim2 of 3 sources checked- cites [43] Little, 2014
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- cites [44] Karin, 2021, Predictors, outcomes, and statistical solutions of missing cases in web-based psychotherapy: methodological replication and elaboration study, JMIR Ment Health source
The Results section (page not provided) reports multiple imputation models that account for baseline symptoms and treatment completion, measured by lessons completed. The cited paper does not establish the additional adjustment for participants’ group; that appears to describe the citing authors’ own analysis. (LLM, conf=0.84)
Experimental — accuracy not yet measured - cites [45] Karin, 2018, Wish You Were Here": examining characteristics, outcomes, and statistical solutions for missing cases in web-based psychotherapeutic trials, JMIR Ment Health source
The Results, Step 3, and Discussion, Principal Findings, support adjusting estimates of missing outcomes for baseline symptom severity and treatment adherence, including lessons completed. The Introduction identifies multiple imputation as a way to handle missing data. The cited paper does not establish treatment group as an adjustment variable in the approach it tested; its reported comparisons used GEE and mixed models rather than multiple imputation. (LLM, conf=0.84)
Experimental — accuracy not yet measured
- Findingown data
The non-completion rate was 34% (n = 51).
“The non-completion rate was 34% (n = 51).”
Quote in the paperSubstantial claim - Findingown data
There were no differences between groups for participants experiencing ≥50% improvements in pain intensity (P = .07).
“There were no differences between groups for participants experiencing ≥50% improvements (P = .07).”
Quote in the paperNot a substantial claim - Findingown data
There were no baseline differences between completers and non-completers on demographics or baseline clinical outcome variables.
“We found no between-group differences when comparing those who did versus did not complete the course on demographics (sex P = .26;age P = .46;total pain locations P = .75)or baseline clinical outcome variables (disability P = .42;anxiety P = .89;depression P = .98;pain intensity P = .96).”
Quote in the paperNot a substantial claim - Findingown data
The number of participants in the treatment group experiencing ≥30% and ≥50% clinical improvements in disability at follow-up remained stable (30%: P = .32; 50%: P = .16).
“The number of participants in the treatment group experiencing ≥30% and ≥50% clinical improvements at followup also remained stable (30%: P = .32;50%: P = .16).”
Quote in the paperSubstantial claim - Findingown data
82% (n = 124) reported the course was worth their time.
“Further, 82% (n = 124) reported the course was worth their time”
Quote in the paperSubstantial claim - Findingown data
The number of participants experiencing ≥30% clinical improvements in pain intensity was significantly greater in the treatment group than the control group (P = .002).
“The number of participants experiencing ≥30% clinical improvements in pain intensity was significantly greater in the treatment group, compared to the control group (P = .002).”
Quote in the paperSubstantial claim - Findingown data
95% (n = 144) of all participants completed the first 2 lessons and were deemed to have engaged in treatment.
“Of all participants, 95% (n = 144) completed the first 2 lessons and were deemed to have engaged in the treatment”
Quote in the paperSubstantial claim - Findingown data
Of 1,333 participants who met eligibility criteria and started treatment in the four RCTs, 152 (11%) were aged 18 to 30 and eligible for the current study.
“Of the 1,333 participants who met eligibility criteria and started the treatment programme from the 4 RCTs (RCT1 n = 62, Mage = 47.8 32 ; RCT2 n = 471, Mage = 50 33 ; RCT3 n = 164, Mage = 48.6 31 ; RCT4 n = 636, Mage = 49 34 ), 152 (11%) were aged between 18 and 30 and were eligible for the current study.”
Quote in the paperSubstantial claim - Findingown data
84% (n = 127) would recommend the course to others.
“and 84% (n = 127) would recommend the course to others.”
Quote in the paperSubstantial claim - Findingown data
Almost 90% of young-adult participants had sought pain-management services from their general practitioner in the 8 weeks prior to registering for the clinical trials.
“Our demographic healthcare usage data indicated that almost 90% of young-adult participants had sought pain-management services from their general practitioner (ie, primary care physician) in the 8-weeks prior to registering for the clinical trials.”
Quote in the paperNot a substantial claim - Findingnone given
Between-group treatment effects were moderate across all outcomes.
“Between-group treatment effects were moderate across all outcomes.”
Quote in the paperSubstantial claim - Findingown data
Significant percent improvements in disability symptoms were found for both groups at both timepoints.
“Significant percent improvements in disability symptoms were also found for both groups, at both timepoints.”
Quote in the paperNot a substantial claim - Findingown data
GEE analyses for anxiety and depression symptoms showed non-significant Group by Time interactions at post-treatment (anxiety: P = .37; depression: P = .20).
“GEE analyses for anxiety and depression symptoms showed non-significant Group by Time interactions at post-treatment (anxiety: P = .37;depression: P = .20)”
Quote in the paperSubstantial claim - Findingown data
At post-treatment, 3% (3/104) of the treatment group and 4% (2/48) of the control group reported increases in pain intensity scores of ≥30% or scores within the clinical range.
“For pain intensity, 3% (3/104) and 4% (2/48) in the treatment and control groups.”
Quote in the paperNot a substantial claim - Findingown data
In the reference group, 86% (n=483) reported the course was worth their time.
“86% (n = 483) reported the course was worth their time”
Quote in the paperNot a substantial claim - Findingown data
GEE analyses for pain intensity showed a non-significant Group by Time interaction at post-treatment (P = .69).
“GEE analyses for pain intensity showed a non-significant Group by Time interaction at post-treatment (P = .69).”
Quote in the paperNot a substantial claim - Findingown data
A significant effect of Group was found across timepoints for both anxiety and depression symptoms.
“A significant effect of Group was found across timepoints for both anxiety and depression symptoms.”
Quote in the paperNot a substantial claim - Findingown data
There were no differences between treatment and control groups in symptom deterioration on any outcome (P range .175-.657).
“There were no differences between treatment and control groups in symptom deterioration on any outcome (P range: .175-.657).”
Quote in the paperSubstantial claim - Findingown data
At post-treatment, 7% (7/104) of the treatment group and 13% (6/48) of the control group reported increases in anxiety scores of ≥30% or scores within the clinical range.
“For anxiety, 7% (7/104) and 13% (6/48) in the treatment and control groups”
Quote in the paperNot a substantial claim - Findingown data
Significant percent improvements in anxiety and depression symptoms were found for both groups at post-treatment and follow-up.
“Significant percent improvements in anxiety and depression symptoms were found for both groups at posttreatment and follow-up.”
Quote in the paperSubstantial claim - Findingown data
Estimated marginal means showed both treatment groups had pre-post improvements in disability.
“Estimated marginal means showed both treatment groups had prepost improvements in disability.”
Quote in the paperNot a substantial claim - Findingown data
For pain-related disability, GEE analyses revealed a non-significant Group by Time interaction at post-treatment (P = .69).
“Regarding pain-related disability, GEE analyses revealed a non-significant Group by Time interaction at post-treatment (P = .69).”
Quote in the paperNot a substantial claim - Findingown data
In the reference group, 88% (n=492) would recommend the course to others.
“88% (n = 492) would recommend the course to others.”
Quote in the paperNot a substantial claim - Findingown data
Estimated marginal means revealed pre-post-treatment improvements in both anxiety and depression symptoms for both groups.
“with estimated marginal means revealing pre-posttreatment improvements in both anxiety and depression symptoms for both groups.”
Quote in the paperSubstantial claim - Findingown data
At post-treatment, 6% (6/104) of the treatment group and 8% (4/48) of the control group reported increases in depression scores of ≥30% or scores within the clinical range.
“for depression, 6% (6/104) and 8% (4/48) in the treatment and control groups, respectively.”
Quote in the paperNot a substantial claim - Findingown data
Estimated marginal means showed both groups had pre-post-treatment improvements in pain intensity.
“Estimated marginal means showed both groups had prepost-treatment improvements in pain intensity.”
Quote in the paperNot a substantial claim - Findingown data
At 3-month follow-up, all treatment group improvements were maintained.
“At 3-month followup, all treatment group improvements were maintained.”
Quote in the paperSubstantial claim - Findingown data
The number of participants experiencing ≥30% and ≥50% clinical improvements in pain intensity at follow-up was maintained.
“The number of participants experiencing ≥30% and ≥50% clinical improvements at follow-up was also maintained.”
Quote in the paperSubstantial claim - Findingown data
At post-treatment, 8% (4/53) of the treatment group and 3% (1/39) of the control group reported increases in disability scores of ≥30% or scores within the clinical range.
“For disability, this was 8% (4/53) and 3% (1/39) in the treatment and control groups, respectively.”
Quote in the paperNot a substantial claim - Findingown data
No adverse effects related to the programme were reported by participants over the course of the trial or during the follow-up period.
“No adverse effects related to the programme were reported by participants over the course of the trial or during the follow-up period.”
Quote in the paperNot a substantial claim - Findingown data
Only one third of young-adult participants had accessed a psychologist for their pain.
“Only one third of participants had accessed a psychologist for their pain.”
Quote in the paperSubstantial claim - Findingown data
In the reference group, 80% (n=447) were 'satisfied' or 'very satisfied' with the programme.
“Eighty percent (n = 447) were 'satisfied' or 'very satisfied' with the programme”
Quote in the paperNot a substantial claim - Findingown data
Significant percent improvements in pain intensity were found for both groups at post-treatment and follow-up.
“Significant percent improvements were also found for both groups at post-treatment and follow-up.”
Quote in the paperNot a substantial claim - Premisecitation
Younger adults are less likely to seek out and engage with treatment than older adults and adolescents.
“Research further afield in mental health has shown that younger adults are less likely to seek out and engage with treatment than older adults and adolescents.[21][22][23]”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [21][22][23]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Study design and conductcitation
The current study pooled data from four CONSORT-compliant RCTs.
“The current study pooled data for participants from four CONSORT-compliant RCTs.[31][32][33][34]”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [31][32][33][34]
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
- Interpretationcitation
Young-adult completion rates in this study are similar to those seen in treatments focusing on mental health in young adults.
“Our young-adult completion rates are similar to what is seen further afield in treatments focussing on mental health in young adults.50,51”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [50] Dear, 2018, Treating anxiety and depression in young adults: a randomised controlled trial comparing clinician-guided versus self-guided Internet-delivered cognitive behavioural therapy, Aust N Z J Psychiatry source
- cites [51] Johnston, 2014, Exploring the efficacy and acceptability of Internet-delivered cognitive behavioural therapy for young adults with anxiety and depression: an open trial, Aust N Z J Psychiatry source
- Interpretationown data
The findings are reasonably stable.
“We can therefore be reasonably comfortable that the findings are stable.”
Quote in the paperSubstantial claim - Study design and conductown data
The questionnaire used to measure disability, the primary outcome, was completed by only 61% of participants.
“While disability was the primary outcome, the questionnaire used to measure this outcome was completed by only 61% of the participants.”
Quote in the paperSubstantial claim - Premisecitation
Evidence suggests that the overall outcomes of Internet-delivered pain interventions are largely maintained up to 12- and 24-months post-treatment, regardless of completion rates.
“However, at the same time, there is evidence to suggest the overall outcomes of Internet-delivered pain interventions are largely maintained up to 12-and 24-months post-treatment, regardless of completion rates.49”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [49] Dear, 2018, The Pain Course: 12- and 24-month outcomes from a randomized controlled trial of an internet-delivered pain management program provided with different levels of clinician support, J Pain source
- Interpretationown data
Overall, the findings indicate that young adults can show improvements following a psychological intervention that is not directly targeted to them, but to all adults.
“Overall, our findings indicate that young adults can show improvements following a psychological intervention that is not directly targeted to them, but to all adults.”
Quote in the paperSubstantial claim - Interpretationown data
At only one third, there are still barriers to young adults accessing the psychological aspect of gold-standard multi-model pain-management.
“However, at only a third, there are clearly still barriers to young adults accessing the psychological aspect of gold-standard multi-model pain-management.”
Quote in the paperSubstantial claim - Study design and conductnone given
The use of a waitlist control meant that control participants crossed over into treatment following post-treatment assessments.
“Second, the use of a waitlist control meant the control participants crossed over into treatment following post-treatment assessments.”
Quote in the paperSubstantial claim - Interpretationown data
The findings highlight that a psychological pain-management intervention designed for adults of any life stage is a viable treatment option for young adults with chronic pain.
“Nevertheless, the findings highlight that a psychological pain-management intervention which has been designed for adults of any life stage is a viable treatment option for young adults with chronic pain.”
Quote in the paperSubstantial claim
- Classified as probably not a substantial claim. 21
- May combine two claims. 56
- The quote only partly states this claim. 1
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataThe reference group of average-age participants (aged 39-63 years) consisted of 561 participants (81% female), which was 42% of the total sample.
“This resulted in a subsample of n = 561 (81% female), which was 42% of the total sample”
Quote in the paperNot a substantial claim1 of 3 sources checked- cites [31] Dear, 2017, The pain course: a randomised controlled trial comparing a remote-delivered chronic pain management program when provided in online and workbook formats, Pain source
- cites [32] Dear, 2013, The Pain Course: a randomised controlled trial of a clinician-guided Internet-delivered cognitive behaviour therapy program for managing chronic pain and emotional well-being, Pain source
- cites [33] Dear, 2015, The Pain Course: a randomised controlled trial examining an internet-delivered pain management program when provided with different levels of clinician support, Pain source
The Methods (section 2.1, page unavailable) state that 490 participants met the trial’s inclusion criteria, with 614 people applying. A subsample of 561 therefore cannot be 42% of this paper’s participant sample; the cited passages also do not identify an average-age reference group aged 39–63. (LLM, conf=0.87)
Checked by a reasoning model — may be wrong.
Experimental — accuracy not yet measured
May combine two claims.
PremisecitationIn recent reviews of psychological pain management for adults with chronic pain and migraine, mean ages were 50 and 39 years, respectively.
“The mean ages in recently published reviews for psychological pain management in adults with chronic pain 16 and migraine 18 were 50-and 39 years, respectively.”
Quote in the paperSubstantial claim1 of 2 sources checkedMay combine two claims.
PremisecitationYoung adults with chronic pain frequently report difficulties seeking out and accessing treatment and can wait months to years for specialist pain management care.
“Similar to adults of all ages, young adults with chronic pain frequently report difficulties seeking out and accessing treatment, 6 and can wait months to years for specialist pain management care.12,13”
Quote in the paperSubstantial claim1 of 3 sources checked- cites [6] Stinson, 2013, Understanding the information and service needs of young adults with chronic pain: perspectives of young adults and their providers, Clin J Pain source
- cites [12] Higginson, 2019, Moving on: transition experiences of young adults with chronic pain, Can J Pain source
The Results (Collaborative systems: The bridge; page unavailable) describe a participant who was still waiting to be seen at an adult chronic pain clinic three years after joining its waiting list. This supports the possibility of a years-long wait for specialist care, but our copy does not establish the claimed months-to-years range. The separate claim about frequently reported access difficulties carries citation 6, not this source’s citation. (LLM, conf=0.82)
Experimental — accuracy not yet measured - cites [13] Hogg, 2012, Waiting in pain: a systematic investigation into the provision of persistent pain services in Australia, Med J Aust source
May combine two claims.
PremisecitationYounger adults are less likely to complete treatment than older adults; a recent study showed young adults had 15% lower completion rates than adults over 30.
“They are also less likely to complete treatment than older adults, 24,25 with a recent study showing young adults had 15% lower completion rates than adults over 30.22”
Quote in the paperSubstantial claim1 of 3 sources checked- cites [24] Wang, 2007, Unmet need for services and interventions among adolescents with mental disorders, Am J Psychiatry source
- cites [25] Edlund, 2002, Dropping out of mental health treatment: patterns and predictors among epidemiological survey respondents in the United States and Ontario, Am J Psychiatry source
- cites [22] Cross, 2022, Factors associated with treatment uptake, completion, and subsequent symptom improvement in a national digital mental health service, Internet Interventions source
Table 2 in Results > Univariate analyses shows lower treatment completion among younger patients: 54.8% for ages 18–24 and 61% for ages 25–35, versus 68.3% for ages 35–45. It does not compare young adults with a single over-30 group or report a 15% lower completion rate, so the specific figure and cutoff are not supported. (LLM, conf=0.86)
Experimental — accuracy not yet measured
May combine two claims.
Study design and conductown dataClinical improvements were comparable within the treatment conditions of RCT2 and RCT3, so the treatment conditions were considered equal and amalgamated into one Treatment group per RCT.
“Analyses showed clinical improvements were comparable within the treatment conditions of both RCTs.Accordingly, the treatment conditions were considered equal and amalgamated into one 'Treatment' group per RCT for the purpose of this study and previously published studies.41,42”
Quote in the paperSubstantial claim1 of 2 sources checked- cites [41] Bisby, 2023, Can internet-delivered pain management programs reduce psychological distress in chronic pain? Exploring relationships between anxiety and depression, pain intensity, and disability, Pain Med source
- cites [42] Bisby, 2023, The timing and magnitude of improvements in depression, anxiety, disability, and pain intensity during an internet-delivered program for chronic pain, J Pain source
The Participants section (page unavailable) says treatment participants from three prior RCTs received the same course and were collapsed into a single sample. The Conclusions section reports no significant difference in the timing of depression and anxiety improvement across guidance conditions. The paper does not say that conditions within RCT2 and RCT3 were deemed equal and amalgamated into one Treatment group per RCT, or that this was done in previously published studies. (LLM, conf=0.84)
Experimental — accuracy not yet measured
May combine two claims.
InterpretationcitationThe significant improvements across outcomes seen in young adults were comparable to those seen in the average-age adult reference group who completed the same pain-management intervention and are consistent with improvements seen in the broader adult population.
“The significant improvements across outcomes seen in young adults were also comparable to those seen in the average-age adult reference group who completed the same pain-management intervention and are consistent with improvements seen in the broader adult population.16,17”
Quote in the paperSubstantial claim1 of 2 sources checked- cites [16] Williams, 2020, Psychological therapies for the management of chronic pain (excluding headache) in adults, Cochrane Database Syst Rev source
Split into 2 atoms — 1 confirmed, 1 partially supported, 0 disputed, 0 misattributed, 0 unverifiable. Expand the claim to see per-atom verdicts.
Experimental — accuracy not yet measured - cites [17] Gandy, 2022, Internet-delivered cognitive and behavioural based interventions for adults with chronic pain: a systematic review and meta-analysis of randomized controlled trials, Pain source
May combine two claims.
InterpretationcitationThe proportion of young adults accessing psychological care (33%) is higher than previous findings in North America (19%), possibly due to how individual and group mental healthcare is partially subsidised by the government in Australia.
“The proportion of young adults accessing psychological care is higher than previous findings in North America (33% vs 19%), 15 possibly due to how individual and group mental healthcare is partially subsidised by the government in Australia.53”
Quote in the paperNot a substantial claim1 of 2 sources checked- cites [15] Murray, 2022, Healthcare transition among young adults with childhood-onset chronic pain: a mixed methods study and proposed framework, J Pain source
- cites [53] Australian Government, Better Access fact sheet – professionals. Department of Health and Aged Care Australia 2019.
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
PremisecitationIn 2 studies that assessed treatment feasibility across adult age groups, uptake and completion increased by age, with significant differences between young and older adults over 60.
“For example, in 2 studies that assessed treatment feasibility across adult age groups, uptake 22 and completion 22,52 increased by age, with significant differences between young and older adults over 60.”
Quote in the paperSubstantial claim2 of 2 sources checked- cites [22] Cross, 2022, Factors associated with treatment uptake, completion, and subsequent symptom improvement in a national digital mental health service, Internet Interventions source
- cites [52] Mewton, 2013, A naturalistic study of the acceptability and effectiveness of internet-delivered cognitive behavioural therapy for psychiatric disorders in older Australians, PLoS One source
The Abstract Results and Discussion say older adults were more likely than younger adults to complete the six iCBT lessons, supporting the completion finding attributed to this paper. The Methods describe tests for significant differences between age groups, but the retrieved passages do not report a statistically significant young-versus-over-60 completion difference. The citing sentence assigns its separate uptake finding to reference 22, not this paper. (LLM, conf=0.78)
Experimental — accuracy not yet measured
May combine two claims.
Study design and conductcitationThe Patient Health Questionnaire 9-Item measure has been shown to be reliable and valid, and its internal consistency in the current study was good (α = .78).
“The measure has been shown to be both reliable and valid, 38 and internal consistency in the current study was good (α = .78).”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [38] Kroenke, 2001, The PHQ-9: validity of a brief depression severity measure, J Gen Intern Med source
Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe percentage of participants reporting improvements of ≥30% and ≥50% was reported based on IMMPACT recommendations.
“Based on the Initiative on Methods, Measurement, and Pain Assessment in Clinical Trials recommendations, 48 the percentage of participants reporting improvements in symptoms of ≥30% and ≥50% from pre-to posttreatment for both groups and pre-treatment to follow-up for the treatment group are reported.”
Quote in the paperNot a substantial claim1 of 1 sources checked- cites [48] Smith, 2020, Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations, Pain source
Probably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataOver the 8 weeks before applying, the number of visits to any healthcare service ranged from 1 to 21.
“Over the eight weeks, the number of visits to any healthcare service ranged from 1 to 21.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThe young adult sample was predominantly female (90%).
“was predominately female (90%)”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe treatment group had significant percent improvements in anxiety (95% CI: 13%, 36%) and depression (95% CI: 18%, 35%) but the control group did not (anxiety: -18%, 17%; depression: -11%, 16).
“Significant percent improvements in anxiety and depression symptoms were also found for the treatment group (95% CIs anxiety: 13%, 36%; depression: 18%, 35%) but not the control group (95% CIs anxiety: -18%, 17%; depression: -11%, 16).”
Quote in the paperSubstantial claimMay combine two claims. The quote only partly states this claim.
Findingown dataAt follow-up, there was no main effect of Time, indicating treatment improvements in disability were maintained at 3 months for the treatment group (P = .25), with percentage improvements (95% CI: 10%, 37%).
“At follow-up, we found no main effect of Time, indicating treatment improvements were maintained at 3-months for the treatment group (P = .25),with percentage improvements in PDI symptoms supporting this (95% CI: 10%, 37%).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor the treatment group, there was no significant effect of Time from post-treatment to follow-up for pain intensity, suggesting improvements were maintained (P = .34).
“For the treatment group, there was no significant effect of Time from post-treatment to follow-up, suggesting improvements were maintained (P = .34).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor anxiety and depression, GEE analyses showed significant Group-by-time interactions at post-treatment (anxiety: P < .001, d = .54; depression: P < .001, d = .67), with larger pre-post improvements in both for the treatment group compared to control.
“For anxiety and depression symptoms, GEE analyses showed significant Group-by-time interactions at posttreatment (anxiety: P < .001,d = .54;depression: P < .001,d = .67),with estimated marginal means revealing larger pre-post-treatment improvements in both anxiety and depression symptoms for the treatment group, compared to the control.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataAverage pain duration in the young adult sample was just under 7 years (range: 6 months to 21 years).
“Average pain duration was just under 7 years (range: 6 months to 21 years).”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown data42% of the young adult sample first experienced chronic pain as a child or adolescent (prior to age 18).
“Forty-two percent of the sample (n = 64) indicated they first experienced chronic pain as a child or adolescent (ie, prior to age 18).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe treatment group had significant percent improvements in pain intensity (95% CI: 6%, 21%) but the control group did not (95% CI: -7%, 12%).
“Significant percent improvements were also found for the treatment group (95% CI: 6%, 21%), but not control (95% CI: -7%, 12%).”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataA third of young adults had seen a psychologist for pain in the 8 weeks before applying.
“with a third reporting they had seen a psychologist.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown data88% of young adults had seen their general medical practitioner for pain in the 8 weeks before applying.
“Most participants had seen their general medical practitioner (88%)”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Findingown dataThe most common pain area reported was the back (76%), followed by the leg/foot (61%).
“The most common pain area reported was the back (76%), followed by the leg/foot (61%).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe number of participants experiencing clinically meaningful improvements of ≥30% and ≥50% on the GAD-7 and PHQ-9 was significantly greater in the treatment group than the control group (anxiety 30%: P < .001, 50%: P = .01; depression 30%: P < .001, 50%: P < .001).
“The number of participants experiencing clinically meaningful improvements of ≥30% and ≥50% on the GAD7 and PHQ9 were significantly greater in the treatment group, compared to the control group (anxiety 30%, 50%: P < .001,P = .01;depression 30%, 50%: P < .001,P < .001,respectively).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe number of participants with PDI scores improving by ≥30% and ≥50% was significantly greater in the treatment group than the control group at post-treatment (30%: P < .001; 50%: P < .001).
“Regarding clinical significance, the number of participants with scores on the PDI improving by ≥30% and ≥50% was significantly greater in the treatment group, than the control group at post-treatment (30%: P < .001;50%: P < .001).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataFor pain-related disability, GEE analyses revealed a significant Group by Time interaction at post-treatment (P = .002, d = .68), with the treatment group showing larger pre-post improvements than controls.
“Regarding pain-related disability, GEE analyses revealed a significant Group by Time interaction at posttreatment (P = .002,d = .68).Estimated marginal means showed the treatment group had larger pre-posttreatment improvements in disability, compared to controls.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe treatment group had significant percent improvements in disability symptoms (95% CI: 7%, 30%) but the control group did not (95% CI: -9%, 13%).
“Significant percent improvements in disability symptoms were also found for the treatment group (95% CI: 7%, 30%) but not the control group (95% CI: -9%, 13%).”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown data88% of the young adult sample reported pain in more than one location.
“The number of pain locations ranged from 1 to 10 or more, with 88% of the sample reporting pain in more than one location.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe rate of participants experiencing ≥30% and ≥50% clinical improvements at follow-up remained stable from post-treatment for anxiety (30%: P = .51; 50%: P = .08) and depression (30%: P = .45; 50%: P = .54).
“The rate of participants experiencing ≥30% and ≥50% clinical improvements at follow-up also remained stable from post-treatment for both anxiety (30%: P = .51;50%: P = .08)and depression (30%: P = .45;50%: P = .54).”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown data70% of the young adult sample reported currently taking medication for pain at the time of application to the research trial.
“Most participants (70%) reported they were currently taking medication for pain at the time of application to the research trial”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown data38% of the young adult sample reported taking medication for their mental health.
“and 38% reported they were taking medication for their mental health.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown data78% (n = 119) of all participants completed at least 4 lessons and were deemed to have adhered.
“and 78% (n = 119) completed at least 4 lessons and were deemed to have adhered.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown dataThe young adult sample had a mean age of 25.8 years (SD = 3.2 years; range 18-30 years).
“Overall, the sample had a mean age of 25.8 years (SD = 3.2 years; range 18-30 years)”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataFor pain intensity, GEE analyses showed a significant Group by Time interaction at post-treatment (P = .005, d = .41), with the treatment group showing larger pre-post improvements than control.
“GEE analyses for pain intensity showed a significant Group by Time interaction at post-treatment (P = .005,d = .41).Estimated marginal means showed the treatment group had larger pre-post-treatment improvements in pain intensity, compared to the control.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe highest median number of visits to any service was 3 (physiotherapist or osteopath), with a median of 2 for most other services.
“The highest median number of visits to any service was 3 (physiotherapist or osteopath), with a median number of visits of 2 for most other services (general practitioner, nurse, psychologist, counsellor/social worker, 'other health service').”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Findingown data58% of young adults had seen a medical specialist for pain in the 8 weeks before applying.
“and/or a medical specialist (58%)”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe treatment group had clinically meaningful reductions in symptoms for all outcomes, and these were maintained at follow-up.
“The treatment group also had clinically meaningful reductions in symptoms for all outcomes, with these maintained at follow-up.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataPost-treatment improvements were equivalent for young-adult and average-aged adult treatment groups, with no significant differences in feasibility or acceptability outcomes.
“Post-treatment improvements were equivalent for young-adult and average-aged adult treatment groups, with no significant differences in feasibility or acceptability outcomes.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataA meaningful proportion of participants did not complete treatment; over one-third of young adults did not access the final lesson.
“While we found no age effects between our 2 samples, it is important to note that a meaningful proportion of participants did not complete treatment.For example, over one-third of young adults did not access the final lesson.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThere was a significant Group by Time interaction for disability, and a posthoc comparison found no differences in demographics or baseline clinical outcome variables between participants who completed the PDI and those who did not.
“However, we found a significant Group by Time interaction for disability, and a posthoc comparison found no differences in demographics or baseline clinical outcome variables between participants who completed the PDI and those who did not (see Table S2 in Supplementary Material).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataAt follow-up, there was a main effect of Time for the reference group indicating pain intensity further improved (P = .02), and it was maintained for the young-adult group (P = .22).
“We found a main effect of Time at follow-up for the reference group, indicating pain intensity further improved for this group (P = .02),and was maintained for the young-adult group (P = .22).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe young-adult group had higher depression symptoms than the average-age group at pre-treatment (P = .05), post-treatment (P = .01), and follow-up (P = .04).
“and depression symptoms (pre: P = .05;post: P = .01;f/u: P = .04).”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataIn the reference group, 96% (n=541) engaged in treatment, 84% (n=472) adhered, and the non-completion rate was 26% (n=146).
“Of this group, 96% (n = 541) engaged in the treatment, and 84% (n = 472) adhered.The non-completion rate was 26% (n = 146).”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataIn the current study, 37%, 25%, 52%, and 47% of young adults made clinical improvements (≥30% improvements) in disability, pain intensity, depression, and anxiety, respectively, immediately post-treatment.
“For example, in the current study 37%, 25%, 52%, and 47% of young adults were found to make clinical improvements (defined as ≥30% improvements) in disability, pain intensity, depression and anxiety, respectively, immediately post-treatment.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataIn the control group, 7%, 10%, 15%, and 17% made such improvements in disability, pain intensity, depression, and anxiety, respectively.
“This compared with 7%, 10%, 15%, and 17% making such improvements in disability, pain intensity, depression and anxiety, respectively, in the control group.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataThe treatment group significantly improved in disability, pain intensity, anxiety symptoms, and depression symptoms post-treatment compared to the control group.
“In line with our expectations, the treatment group significantly improved in disability, pain intensity, anxiety symptoms and depression symptoms post-treatment, compared to the control group.”
Quote in the paperSubstantial claimMay combine two claims.
Findingnone givenTreatment engagement was high; however, around one third of participants did not complete the intervention.
“Treatment engagement was high; however, around one third of participants did not complete the intervention.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe young-adult group had higher anxiety symptoms than the average-age group at pre-treatment (P = .001), post-treatment (P = .001), and follow-up (P = .01).
“Estimated marginal means at each timepoint revealed the young-adult group had higher anxiety symptoms (pre: P = .001;post: P = .001;f/u: P = .01)”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThe treatment was deemed acceptable, with most participants endorsing they would recommend it to others with chronic pain.
“The treatment was deemed acceptable; with most endorsing they would recommend it to others with chronic pain.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingown dataThere were no significant differences between the young-adult and average-age participant groups on engagement, adherence, completion, satisfaction, perceived worth of time, or recommendation of the programme.
“Chi-square analyses indicated no significant differences between the young and averageage participant groups on engagement (χ 2 = .91,P = .34),adherence (χ 2 = 2.88, P = .09),or completion (χ 2 = 3.39, P = .07).”
- Also stated in: § Examining Age Effects on Outcomes · plain
“Chi-square analyses indicated no significant differences between the groups on satisfaction (χ 2 = .54,P = .46),time (χ 2 = .00,P = .98),or recommendation (χ 2 = .18,P = .67).”
- Also stated in: § Discussion · plain
“Regarding feasibility and acceptability, there were no differences between our young adult and average adult samples in rates of engagement, adherence, completion, or in treatment satisfaction.”
Quote in the paperSubstantial claim- Also stated in: § Examining Age Effects on Outcomes · plain
May combine two claims.
Findingown dataIn the current study, 95%, 78%, 66%, and 85% of younger adults engaged, adhered, completed, and reported being satisfied with the treatment, respectively.
“In the current study, 95%, 78%, 66%, and 85% of younger adults were found to engage, adhere, complete and report being satisfied with the treatment, respectively.”
Quote in the paperSubstantial claimMay combine two claims.
Findingown dataTwo thirds of participants deteriorated on one outcome, and the remaining third deteriorated across 2 outcomes.
“Two thirds of participants deteriorated on one outcome, with the remaining third deteriorating across 2.”
Quote in the paperNot a substantial claimMay combine two claims.
Findingnone givenThe intervention was found to be acceptable and engagement levels were high.
“The intervention was found to be acceptable and engagement levels were high.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductown dataThe four source RCTs were pre-registered on the Australian New Zealand Clinical Trials Registry.
“RCTs were pre-registered on the Australian New Zealand Clinical Trials Registry (ACTRN12611000894998; ACTRN12613000252718; ACTRN12614000768695; ACTRN12615001003561).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites ACTRN12611000894998; ACTRN12613000252718; ACTRN12614000768695; ACTRN12615001003561
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenThe current study deviated from its protocol by reversing the aims and by conducting analyses comparing the young-adult sample with a second sample of adults from the four RCTs.
“We deviated from the protocol in the following ways: 1) the aims of the study are reversed, and we present the feasibility aim prior to clinical efficacy, and 2) we conducted analyses comparing our young-adult sample with a second sample of adults taken from the 4 RCTs.”
Quote in the paperNot a substantial claimMay combine two claims.
PremisecitationLess than a fifth of young adults with chronic pain surveyed were receiving psychological support, although psychological intervention remains a recommended first-line treatment.
“although psychological intervention remains a recommended first-line treatment, a recent study found that less than a fifth of young adults surveyed were receiving psychological support. 2”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [2] Murray, 2022, The prevalence of chronic pain in young adults: a systematic review and meta-analysis, Pain source
Probably not a substantial claim: may not pass S3 (load-bearing).
Study design and conductcitationA protocol for the current study, with a data-analysis plan, was pre-registered on OSF in May 2022.
“A protocol for the current study, with a data-analysis plan, was pre-registered on OSF in May 2022 (https://doi.org/10.17605/OSF.IO/84YJQ).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites https://doi.org/10.17605/OSF.IO/84YJQ
Couldn’t be matched to a paper in Crossref, so it can’t be checked.
May combine two claims.
Interpretationown dataThe treatment group significantly improved across all outcomes compared with control, with improvements maintained at follow-up.
“The treatment group significant improved across all outcomes, compared with control, with improvements maintained at follow-up.”
Quote in the paperSubstantial claimMay combine two claims.
InterpretationreasoningThe intervention's features (online, free, available throughout the country, transdiagnostic, limited exclusions) increase the representativeness of the sample and its applicability in the real world.
“These features increase the representativeness of the sample, and thus its applicability in the real world.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductcitationThe Pain Disability Inventory has sound psychometric properties, and its internal consistency in the current study was good (α = .86).
“The PDI has been shown to have sound psychometric properties, 36 and the internal consistency of the items in the current study was good (α = .86).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [36] Tait, 1987, The Pain Disability Index: psychometric and validity data, Arch Phys Med Rehabil
Not checked in the free run.
May combine two claims.
Interpretationown dataYoung adults had high engagement and acceptability ratings, though 34% did not complete the intervention.
“Young adults had high engagement and acceptability ratings, though 34% did not complete the intervention.”
Quote in the paperSubstantial claimClassified as probably not a substantial claim. May combine two claims.
InterpretationreasoningThe absence of significant differences in the current study is unexpected, and caution is needed in drawing firm conclusions.
“Hence, the absence of significant differences in the current study is unexpected, and some caution is arguably needed in drawing firm conclusions just yet.”
Quote in the paperSubstantial claimProbably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationNumerical rating scales are recommended for assessing pain intensity.
“Numerical ratings scales are recommended for assessing pain intensity.40”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [40] Turk, 2003, Core outcome domains for chronic pain clinical trials: IMMPACT recommendations, Pain source
Probably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductcitationThe Generalised Anxiety Disorder 7-Item measure has been shown to be reliable and valid for a range of anxiety disorders, and its internal consistency in the current study was excellent (α = .90).
“The measure has been shown to be both reliable and valid for a range of anxiety disorders, 37 and internal consistency in the current study was excellent (α = .90).”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [37] Spitzer, 2006, A brief measure for assessing generalized anxiety disorder: the GAD-7, Arch Intern Med source
May combine two claims.
Interpretationown dataYoung adults can engage with and show improvements following a psychological pain-management intervention designed for all adults with chronic pain.
“Findings indicate young adults can engage with and show improvements following a psychological pain-management intervention designed for all adults with chronic pain.”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataAn Internet-delivered psychological pain-management intervention is acceptable and clinically efficacious for improving disability, anxiety, depression, and pain intensity in young adults (18-30) with chronic pain.
“Secondary analysis of data from 4 RCTs found an Internet-delivered psychological pain-management intervention acceptable and clinically efficacious for improving disability, anxiety, depression and pain intensity in young adults (18-30) with chronic pain.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductreasoningWe are unable to conduct longer term evaluations of treatment efficacy and are uncertain whether the maintained improvements at 3-months follow-up are a result of the intervention or other non-treatment related factors such as increased healthcare or medication usage, or natural remission.
“We are therefore unable to conduct longer term evaluations of treatment efficacy and are uncertain whether the maintained improvements at 3-months follow-up are a result of the intervention or other non-treatment related factors such as increased healthcare or medication usage, or natural remission.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductreasoningThe content of the course included adults of all ages, and outcomes were not specific to the young-adult population.
“Finally, the content of the course (eg, case stories, examples) included adults of all ages and outcomes were not specific to our population.”
Quote in the paperSubstantial claimMay combine two claims.
Interpretationown dataUsing pre-existing data allowed us to answer our research questions and determine that broad adult content was largely acceptable and efficacious for young adults.
“Using pre-exiting data allowed us to answer our research questions and determine that broad adult content was largely acceptable and efficacious for young adults.”
Quote in the paperSubstantial claimMay combine two claims.
Study design and conductown dataWe were unable to report on the race, ethnicity, or gender identity of participants, so we cannot be certain how representative our sample was of emerging adults, nor whether findings would translate to all young people.
“We were unable to report on the race, ethnicity, or gender identity of participants as this information was not initially captured.Thus, we cannot be certain how representative our sample was of emerging adults, nor whether findings would translate to all young people.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S3 (load-bearing). May combine two claims.
Study design and conductnone givenWe were unable to assess whether the pattern of findings was impacted by trial cohort, or whether there were any moderators or predictors of treatment efficacy.
“Third, we were unable to assess whether the pattern of findings was impacted by trial cohort, or whether there were any moderators or predictors of treatment efficacy.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationown dataGood clinical outcomes were observed at post-treatment and follow-up and were comparable to outcomes from a broader adult population.
“Good clinical outcomes were observed at post-treatment and follow-up and were comparable to outcomes from a broader adult population.”
Quote in the paperSubstantial claim
The paper relies on this without support.
This is one of the first studies to assess the efficacy of a psychological pain-management programme in young adults with chronic pain.
“This is one of the first studies to assess the efficacy of a psychological pain-management programme in young adults with chronic pain.”
The paper relies on this without support.
Psychological management is a first-line treatment for chronic pain, young adults report difficulties accessing appropriate pain services, and very few studies have investigated how this emerging adult population responds to psychological intervention.
“While psychological management is a first-line treatment for chronic pain, young adults report difficulties with accessing appropriate pain services and very few studies have investigated how this emerging adult population responds to psychological intervention.”
The paper relies on this without support.
The final lesson or module of most Internet-delivered pain management interventions typically focuses on helping people think about and develop plans for managing pain over the longer term, covering issues like lapse management.
“The final lesson or module of most Internet-delivered pain management interventions typically focus on helping people think about and develop plans for managing pain over the longer term, covering issues like lapse management.”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
High-school-diploma percentage is too high
MinorThe reported 33 participants are 21.7% of the overall sample of 152, rather than 48%.
Reported 48 · recomputed 21.710526
“High school diploma 33 (48%) 18 (17%) 15 (31%)”
Some-high-school percentage is too high
MinorThe table lists 15 of 152 participants in this education category, which is 9.9%, not 18%.
Reported 18 · recomputed 9.868421
“OVERALL (N = 152) TREATMENT (N = 104) CONTROL (N = 48) Age, Mean (sd) 25.8 (3.2) 25.8 (3.0) 25.8 (3.6) Sex, female 137 (90%) 95 (91%) 42 (88%) Relationship status Single 77 (51%) 52 (50%) 25 (52%) In a relationship 64 (42%) 44 (42%) 20 (42%) Divorced/Separated 1 (1%) 1 (1%) 0 (0%) Other 10 (7%) 7 (7%) 3 (6%) Education Some high school 15 (18%)”
Young-adult satisfaction percentage does not match the stated respondents
MinorAmong the 131 participants who completed the questionnaire, 118 satisfied participants represent 90.1%, not 85%.
Reported 85 · recomputed 90.076336
“completed the post-treatment acceptability questionnaire (n = 131), 85% (n = 118) were 'satisfied' or 'very satisfied' with the programme.”
Cites
Statistical Power Analysis for the Behavioral Sciences
Muller, K. E., & Cohen, J. (1989) · Technometrics · doi:10.2307/1270020 · Cited by 99,588 · see citing works
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910 · see citing works
A Brief Measure for Assessing Generalized Anxiety Disorder: The GAD-7
Spitzer, R. L., Kroenke, K., Williams, J. B. W., & Löwe, B. (2006) · Archives of Internal Medicine · doi:10.1001/archinte.166.10.1092 · Cited by 31,765 · see citing works
Emerging adulthood: A theory of development from the late teens through the twenties.
Arnett, J. J. (2000) · American Psychologist · doi:10.1037/0003-066x.55.5.469 · Cited by 16,843 · see citing works
Lakens, D. (2013) · Frontiers in Psychology · doi:10.3389/fpsyg.2013.00863 · Cited by 10,303 · see citing works
Statistical Analysis with Missing Data
Little, R. J. A., & Rubin, D. B. (2002) · Wiley Series in Probability and Statistics · doi:10.1002/9781119013563 · Cited by 8,473 · see citing works
Core outcome domains for chronic pain clinical trials: IMMPACT recommendations
Turk, D. C., Dworkin, R. H., Allen, R. R., Bellamy, N., Brandenburg, N., Carr, D. B., Cleeland, C., Dionne, R., Farrar, J. T., Galer, B. S., et al. (2003) · Pain · doi:10.1016/j.pain.2003.08.001 · Cited by 3,510 · see citing works
Roderick J.A. Little, Donald B. Rubin — Statistical Analysis with Missing Data
Bo., N., Little, R. J. A., & Rubin, D. B. (1988) · Population · doi:10.2307/1533221 · Cited by 2,155 · see citing works
Age-related change in executive function: Developmental trends and a latent variable analysis
Huizinga, M., Dolan, C. V., & van der Molen, M. W. (2006) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2006.01.010 · Cited by 1,636 · see citing works
Psychological therapies for the management of chronic pain (excluding headache) in adults
Williams, A. C. D. C., Eccleston, C., & Morley, S. (2012) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007407.pub3 · Cited by 1,634 · see citing works
Development of the Wisconsin Brief Pain Questionnaire to assess pain in cancer and other diseases
Daut, R. L., Cleeland, C. S., & Flanery, R. C. (1983) · Pain · doi:10.1016/0304-3959(83)90143-4 · Cited by 1,562 · see citing works
SCHULENBERG, J. E., SAMEROFF, A. J., & CICCHETTI, D. (2004) · Development and Psychopathology · doi:10.1017/s0954579404040015 · Cited by 663 · see citing works
Psychological therapies for the management of chronic pain (excluding headache) in adults
Williams, A. C. D. C., Fisher, E., Hearn, L., & Eccleston, C. (2020) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007407.pub4 · Cited by 605 · see citing works
(1987) · PubMed · Cited by 587 · see citing works
Executive function across the life span
Zelazo, P. D., Craik, F. I. M., & Booth, L. (2004) · Acta Psychologica · doi:10.1016/j.actpsy.2003.12.005 · Cited by 586 · see citing works
Edlund, M. J., Wang, P. S., Berglund, P. A., Katz, S. J., Lin, E., & Kessler, R. C. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.5.845 · Cited by 439 · see citing works
Murray, C. B., Groenewald, C. B., de la Vega, R., & Palermo, T. M. (2019) · Pain · doi:10.1097/j.pain.0000000000001732 · Cited by 225 · see citing works
Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations
Smith, S. M., Dworkin, R. H., Turk, D. C., McDermott, M. P., Eccleston, C., Farrar, J. T., Rowbotham, M. C., Bhagwagar, Z., Burke, L. B., Cowan, P., et al. (2020) · Pain · doi:10.1097/j.pain.0000000000001952 · Cited by 194 · see citing works
Dear (2015) · doi:10.1097/j.pain.0000000000000251 · Cited by 187 · see citing works
Self-citationDear, B. F., Titov, N., Perry, K. N., Johnston, L., Wootton, B. M., Terides, M. D., Rapee, R. M., & Hudson, J. L. (2013) · Pain · doi:10.1016/j.pain.2013.03.005 · Cited by 182 · see citing works
Self-citationHerbert, M. S., Afari, N., Liu, L., Heppner, P., Rutledge, T., Williams, K., Eraly, S., VanBuskirk, K., Nguyen, C., Bondi, M., et al. (2017) · The Journal of Pain · doi:10.1016/j.jpain.2016.10.014 · Cited by 137 · see citing works
Long-Term Outcomes of Adolescents With Juvenile-Onset Fibromyalgia in Early Adulthood
Kashikar-Zuck, S., Cunningham, N., Sil, S., Bromberg, M. H., Lynch-Jordan, A. M., Strotman, D., Peugh, J., Noll, J., Ting, T. V., Powers, S. W., et al. (2014) · Pediatrics · doi:10.1542/peds.2013-2220 · Cited by 135 · see citing works
Hogg, M. N., Gibson, S., Helou, A., DeGabriele, J., & Farrell, M. J. (2012) · Medical Journal of Australia · doi:10.5694/mja12.10140 · Cited by 133 · see citing works
The prevalence of chronic pain in young adults: a systematic review and meta-analysis
Murray, C. B., de la Vega, R., Murphy, L. K., Kashikar-Zuck, S., & Palermo, T. M. (2022) · Pain · doi:10.1097/j.pain.0000000000002541 · Cited by 133 · see citing works
Unmet need for services and interventions among adolescents with mental disorders
Wang, P. S., Sherrill, J., & Vitiello, B. (2007) · American Journal of Psychiatry · doi:10.1176/ajp.2007.164.1.1 · Cited by 123 · see citing works
Unmet need for services and interventions among adolescents with mental disorders.
Wang, P. S., Sherrill, J. T., & Vitiello, B. (2007) · American Journal of Psychiatry · doi:10.1176/appi.ajp.164.1.1 · Cited by 116 · see citing works
D’Souza, P. J., Lumley, M. A., Kraft, C. A., & Dooley, J. A. (2008) · Annals of Behavioral Medicine · doi:10.1007/s12160-008-9046-7 · Cited by 109 · see citing works
Gandy, M., Pang, S. T. Y., Scott, A. J., Heriseanu, A. I., Bisby, M. A., Dudeney, J., Karin, E., Titov, N., & Dear, B. F. (2022) · PAIN · doi:10.1097/j.pain.0000000000002606 · Cited by 102 · see citing works
Self-citationFeuille, M., & Pargament, K. (2015) · Journal of Health Psychology · doi:10.1177/1359105313508459 · Cited by 101 · see citing works
Dear, B. F., Fogliati, V. J., Fogliati, R., Johnson, B., Boyle, O., Karin, E., Gandy, M., Kayrouz, R., Staples, L. G., & Titov, N. (2018) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867417738055 · Cited by 93 · see citing works
Self-citationStinson, J., White, M., Isaac, L., Campbell, F., Brown, S., Ruskin, D., Gordon, A., Galonski, M., Pink, L., Buckley, N., et al. (2013) · The Clinical Journal of Pain · doi:10.1097/ajp.0b013e31826dce65 · Cited by 81 · see citing works
Rosenbloom, B. N., Rabbitts, J. A., & Palermo, T. M. (2017) · Pain · doi:10.1097/j.pain.0000000000000888 · Cited by 81 · see citing works
Karin, E., Dear, B. F., Heller, G. Z., Crane, M. F., & Titov, N. (2018) · JMIR Mental Health · doi:10.2196/mental.8363 · Cited by 67 · see citing works
Self-citationPsychological therapies for the prevention of migraine in adults
Sharpe, L., Dudeney, J., Williams, A. C. D. C., Nicholas, M., McPhee, I., Baillie, A., Welgampola, M., & McGuire, B. (2019) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd012295.pub2 · Cited by 59 · see citing works
Dear, B. F., Gandy, M., Karin, E., Ricciardi, T., Fogliati, V. J., McDonald, S., Staples, L. G., Perry, K. N., Sharpe, L., Nicholas, M. K., et al. (2017) · Pain · doi:10.1097/j.pain.0000000000000916 · Cited by 57 · see citing works
Self-citationCross, S. P., Karin, E., Staples, L. G., Bisby, M. A., Ryan, K., Duke, G., Nielssen, O., Kayrouz, R., Fisher, A., Dear, B. F., et al. (2022) · Internet Interventions · doi:10.1016/j.invent.2022.100506 · Cited by 57 · see citing works
Self-citationAge differences in cognitive–affective processes in adults with chronic pain
Murray, C. B., Patel, K. V., Twiddy, H., Sturgeon, J. A., & Palermo, T. M. (2021) · European Journal of Pain · doi:10.1002/ejp.1725 · Cited by 54 · see citing works
A scoping review of chronic pain in emerging adults
Brown, D., Schenk, S., Genent, D., Zernikow, B., & Wager, J. (2021) · PAIN Reports · doi:10.1097/pr9.0000000000000920 · Cited by 53 · see citing works
Dear, B. F., Gandy, M., Karin, E., Fogliati, R., Fogliati, V. J., Staples, L. G., Wootton, B. M., Sharpe, L., & Titov, N. (2018) · The Journal of Pain · doi:10.1016/j.jpain.2018.07.005 · Cited by 51 · see citing works
Self-citationGrowing pains: understanding the needs of emerging adults with chronic pain
Twiddy, H., Hanna, J. E., & Haynes, L. (2017) · British Journal of Pain · doi:10.1177/2049463717709641 · Cited by 49 · see citing works
Mewton, L., Sachdev, P. S., & Andrews, G. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071825 · Cited by 48 · see citing works
Moving on: transition experiences of young adults with chronic pain
Higginson, A., Forgeron, P., Harrison, D., Finley, G. A., & Dick, B. D. (2019) · Canadian Journal of Pain · doi:10.1080/24740527.2019.1587707 · Cited by 40 · see citing works
Pain Relief as a Motivation for Cannabis Use Among Young Adult Users With and Without Chronic Pain
Fales, J. L., Ladd, B. O., & Magnan, R. E. (2019) · Journal of Pain · doi:10.1016/j.jpain.2019.02.001 · Cited by 37 · see citing works
Johnston, L., Dear, B. F., Gandy, M., Fogliati, V. J., Kayrouz, R., Sheehan, J., Rapee, R. M., & Titov, N. (2014) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/0004867414527524 · Cited by 36 · see citing works
Self-citationKarin, E., Crane, M. F., Dear, B. F., Nielssen, O., Heller, G. Z., Kayrouz, R., & Titov, N. (2021) · JMIR Mental Health · doi:10.2196/22700 · Cited by 36 · see citing works
Self-citationDear, B. F., Karin, E., Fogliati, R., Dudeney, J., Nielssen, O., Gandy, M., Staples, L., Scott, A. J., Heriseanu, A. I., Bisby, M. A., et al. (2022) · Pain · doi:10.1097/j.pain.0000000000002507 · Cited by 33 · see citing works
Self-citationWaldie, K. E., Poulton, R., & DCP (2002) · Headache The Journal of Head and Face Pain · doi:10.1046/j.1526-4610.2002.02148.x · Cited by 29 · see citing works
Murray, C. B., Murphy, L. K., Jordan, A., Owens, M. T., McLeod, D., & Palermo, T. M. (2022) · The Journal of Pain · doi:10.1016/j.jpain.2022.02.010 · Cited by 21 · see citing works
Dear, B. F., Courtney, C., Khor, K. E., McDonald, S., Ricciardi, T., Gandy, M., Fogliati, V. J., & Titov, N. (2018) · The Clinical Journal of Pain · doi:10.1097/ajp.0000000000000565 · Cited by 19 · see citing works
Self-citationWestendorp, T., Verbunt, J., Remerie, S. C., de Blécourt, A. C. E., Baalen, B. V., & Smeets, R. (2016) · European Journal of Pain · doi:10.1002/ejp.836 · Cited by 14 · see citing works
Bisby, M. A., Chandra, S. S., Dudeney, J., Scott, A. J., Titov, N., & Dear, B. F. (2023) · Pain Medicine · doi:10.1093/pm/pnac158 · Cited by 13 · see citing works
Self-citationFactors influencing emerging adults' use of outpatient mental health services
Black, S. R., Fristad, M. A., Arnold, L. E., Birmaher, B., Findling, R. L., Youngstrom, E. A., & Horwitz, S. M. (2019) · Evidence-Based Practice in Child and Adolescent Mental Health · doi:10.1080/23794925.2018.1501328 · Cited by 4 · see citing works
Bisby, M. A., Chandra, S. S., Scott, A. J., Dudeney, J., Titov, N., & Dear, B. F. (2023) · The Journal of Pain · doi:10.1016/j.jpain.2023.06.004 · Cited by 4 · see citing works
Self-citationPollard, C. A. (1984) · PsycTESTS Dataset · doi:10.1037/t67378-000 · Cited by 3 · see citing works
Fales, J., Ladd, B., Magnan, R., et al. (2018) · The Journal of Pain · doi:10.1016/j.jpain.2017.12.133
Karin, E., Dear, B. F., Heller, G. Z., et al. (2017) · doi:10.2196/preprints.8363
Self-citationKarin, E., Crane, M. F., Dear, B. F., et al. (2020) · doi:10.2196/preprints.22700
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Anxiety and Depression in Youth With Chronic Pain
Dudeney, J. E., Aaron, R. V., Hathway, T., Bhattiprolu, K., Bisby, M. A., McGill, L., Gandy, M., Harte, N., & Dear, B. F. (2024) · Archives of Pediatrics and Adolescent Medicine · doi:10.1001/jamapediatrics.2024.3039 · Cited by 95 · see citing works
Self-citationHarte, N., Aaron, R. V., Bhattiprolu, K., Bisby, M. A., Gandy, M., Hathway, T., Dear, B. F., & Dudeney, J. E. (2024) · Journal of Psychosomatic Research · doi:10.1016/j.jpsychores.2024.111945 · Cited by 30 · see citing works
Self-citationSelf-management and coping in young adults with chronic pain: A reflexive thematic analysis
Karadag, P., Taylor, J. H., & Burton, A. E. (2025) · Journal of Health Psychology · doi:10.1177/13591053251344236 · Cited by 3 · see citing works
“Nevertheless, young adults in the treatment group improved across outcomes of disability, and such improvements were maintained at follow-up (Dudeney et al., 2024).”
Atkinson-Graham, M., Yu, H., Cooper, L., Weisberg, J., Connell, G. P., Allard, S., Check, L., Nkamtchoum, A. F., Flynn, T., Lorca, J., et al. (2026) · Journal of Occupational Rehabilitation · doi:10.1007/s10926-025-10354-8
Eather, C.-E., Sullivan, C. M., Sterling, M. M., Armfield, N. R., Liimatainen, J., Chandra, S. S., & Elphinston, R. A. (2026) · Pain · doi:10.1097/j.pain.0000000000003959
Smith, M. G., Schaly, S., Berryman, C. F., Khillan, A., Ostojic, K., & Harvey, A. R. (2026) · Journal of Pain Research · doi:10.2147/jpr.s601477
Sheykhangafshe, F. B., Farahani, H., Watson, P., et al. (2026) · Pain Research and Management · doi:10.1155/prm/9958741
- Authors
- Dudeney, J., Scott, A. J., Hathway, T., Bisby, M. A., Harte, N., Titov, N., & Dear, B. F.
- Affiliations
- Macquarie University (AU)
- ORCID
- Venue
- The Journal of Pain
- Publisher
- Elsevier BV
- Published
- 2024-06
- Volume
- 25
- Issue
- 6
- Pages
- 104447
- ISSN
- 1526-5900 (ISSN-L)
- OpenAlex
- W4389903794
- Semantic Scholar
- 33f92e7041f9ead10fbfcc2cf97c9a4d9345d8cc
- Cited by
- 9
- References
- 54
- Citations by year
- 2026: 5 · 2025: 2 · 2024: 2
- FWCI
- 2.32
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Pain (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Macquarie University (EES2022, MQRF0001007)
- Topics
- Social Sciences › Psychology › Applied Psychology › Digital Mental Health Interventions
- Health Sciences › Medicine › Pharmacology › Musculoskeletal pain and rehabilitation
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Pediatric Pain Management Techniques
- Keywords
- online intervention, psychological pain management, chronic pain, young adults, feasibility, acceptability, treatment engagement, medication adherence, pain intensity, disability, anxiety, depression
- MeSH terms
- Internet-Based Intervention, Adolescent, Adult, Anxiety, Feasibility Studies, Female, Humans, Male, Patient Acceptance of Health Care, Telemedicine, Internet, Young Adult, Chronic Pain, Pain Management
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Claims read by deepseek-v4.1-flash under definition version 3 (extract-v3) on 2026-10-11.
Classified by jev-1.13-20260917 (gold-guideline-v0.2) on 2026-10-11.
Cited sources are checked by gpt-6-sol.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review