CoChat
Sign Up
Cited by 96Cancer survivorship and carePain Management and Opioid UsePalliative and Oncologic Care

Symptom management for cancer patients: a trial comparing two multimodal interventions

Open access
Sikorskii, Alla, Given, Charles W., Given, Barbara, Jeon, Sangchoon, Decker, Veronica, Decker, David, Champion, Victoria, McCorkle, Ruth·2007·Journal of Pain and Symptom Management
DOI 10.1016/j.jpainsymman.2006.11.018PMC PMC2043403
Open this paper in CoChat — free accountOpen PDF

Abstract

The results of a randomized controlled trial that tested the effects of eight-week, six-contact multidimensional interactive interventions for symptom management are presented. Four hundred and thirty-five cancer patients with solid tumors undergoing chemotherapy were randomized to receive either nurse-assisted symptom management (NASM) or automated telephone symptom management (ATSM). A prior trial established the effectiveness of NASM compared with conventional care. Seventeen symptoms commonly experienced by patients undergoing chemotherapy were rated on a scale from 0 to 10 and were evaluated at baseline, at each of the six intervention contacts, and postintervention observation at 10 weeks. Both groups achieved significant reduction in symptom severity over baseline, and there was no difference between groups on symptom severity at 10 weeks. Randomization accounted for possible reductions in severity due to response shifts. Severity of symptoms reported by patients at each of the six intervention contacts was measured using a Rasch model. Symptom pattern was different for lung and non-lung cancer patients, and they were analyzed separately. Longitudinal analyses revealed that lung cancer patients with greater symptom severity withdrew from later intervention contacts of the ATSM. The results suggest that both NASM and ATSM achieved a clinically significant reduction in symptom severity. The NASM may be more effective than ATSM in retaining lung cancer patients in the intervention. Further testing of ATSM supplemented by NASM for patients with severe symptoms is warranted.

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.1016/j.jpainsymman.2006.11.018

Cites

42 of 42 references verified0 citation errors · 0 not checkable

Statistics

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • The Enhancing Connections Program was designed to address distress in mothers with breast cancer and negative adjustment of their school-age children.

    “Recognizing the vulnerabilities of families and caregivers during the cancer treatment phase of the cancer-care continuum, the Enhancing Connections Program (EC)18 was designed to deal with the distress experienced by mothers with breast cancer and the negative adjustment of their school-age children.”

    From Self-management: Enabling and empowering patients living with cancer as a chronic illness (2011) · cites this paper as [18]

  • In the EC Program, participants' pre- and post-test measures of depression (p=.03), anxiety (p=.02), and self-confidence (p=.006) improved significantly.

    “Participants' pre- and post-test measures of depression (p=.03), anxiety (p=.02), and self-confidence (p=.006) improved significantly.”

    From Self-management: Enabling and empowering patients living with cancer as a chronic illness (2011) · cites this paper as [18]

  • In the EC Program, mothers and fathers reported significant decreases in their children's behavioral problems, and children reported less cancer-related worry (p=.04).

    “Mothers and fathers also reported significant decreases in their children's behavioral problems. The children themselves reported less cancer-related worry (p=.04).”

    From Self-management: Enabling and empowering patients living with cancer as a chronic illness (2011) · cites this paper as [18]

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Cites

Flagged first, then by citations

Research works printed but not linked: 6

  1. Cleeland C, Mendoza T, Wang X, et al. Assessing symptom distress in cancer patients. Cancer 2000; 89:634e1646.
  2. National Institutes of Health. Symptom man- agement in cancer: pain, depression, and fatigue. State of the Science Conference Statement, NCI; 2002.
  3. Hazlett-Stevens H, Craske M. In: Bond FW, Dryden W, eds. Brief cognitive-behavioral therapy: Definition and scientific foundations in handbook of brief cognitive behavior therapy. New York: John Wiley and Sons Ltd, 2002: 1e20.
  4. Yates P, Aranda S, Hargraves M. Randomized controlled trial of an educational intervention for managing fatigue in women receiving adjuvant che- motherapy. J Clin Oncol 2005;23:6027e6036.
  5. Balas EA, Jaffrey F, Kuperman G, et al. Elec- tronic communication with patients. JAMA 1997; 278:152e159.
  6. Linacre JM, Wright BD. A user's guide to WIN- STEPS: Rasch model computer program. Chicago, IL: MESA Press, 2000.

Cited by

Sorted by citations

Related

Authors
Sikorskii, A., Given, C. W., Given, B., Jeon, S., Decker, V., Decker, D., Champion, V., & McCorkle, R.
Affiliations
  • Yale University (US)
  • Indiana University Health (US)
Corresponding author
Given, Charles W.
ORCID
Venue
Journal of Pain and Symptom Management
Publisher
Elsevier BV
Published
2007-09
Volume
34
Issue
3
Pages
253-264
ISSN
0885-3924 (ISSN-L)
DOI
10.1016/j.jpainsymman.2006.11.018
PMC
PMC2043403
OpenAlex
W2027055579
Cited by
96
References
42
Citations by year
2026: 1 · 2025: 2 · 2024: 1 · 2023: 4 · 2022: 3 · 2021: 4 · 2020: 3 · 2019: 5 · 2018: 5 · 2017: 6 · 2016: 4 · 2015: 6 · 2014: 8 · 2013: 9 · 2012: 8
FWCI
3.53
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of Pain and Symptom Management (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Cancer Institute (R01CA030724)
Topics
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Health Sciences › Medicine › Anesthesiology and Pain Medicine › Pain Management and Opioid Use
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
Keywords
cancer symptom management, chemotherapy-induced symptoms, multimodal intervention, lung cancer, solid tumors, intervention retention, response shift, Rasch model
MeSH terms
Aged, Antineoplastic Agents, Automation, Data Interpretation, Statistical, Female, Humans, Longitudinal Studies, Lung Neoplasms, Male, Middle Aged, Neoplasms, Nursing Care, Severity of Illness Index, Telephone

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review