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Mind-Body Treatments for the Pain-Fatigue-Sleep Disturbance Symptom Cluster in Persons with Cancer
Open accessAbstract
Context Co-occurring pain, fatigue, and sleep disturbance comprise a common symptom cluster in patients with cancer. Treatment approaches that target the cluster of symptoms rather than just a single symptom need to be identified and tested.Objectives To synthesize evidence regarding mind-body interventions that have shown efficacy in treating two or more symptoms in the pain-fatigue-sleep disturbance cancer symptom cluster.Methods A literature search was conducted using CINAHL, Medline, and PsychInfo databases through March 2009. Studies were categorized based on the type of mind-body intervention (relaxation, imagery/hypnosis, cognitive-behavioral therapy/coping skills training [CBT/CST], meditation, music, and virtual reality), and a preliminary review was conducted with respect to efficacy for pain, fatigue, and sleep disturbance. Mind-body interventions were selected for review if there was evidence of efficacy for at least two of the three symptoms. Forty-three studies addressing five types of mind-body interventions met criteria and are summarized in this review.Results Imagery/hypnosis and CBT/CST interventions have produced improvement in all the three cancer-related symptoms individually: pain, fatigue, and sleep disturbance. Relaxation has resulted in improvements in pain and sleep disturbance. Meditation interventions have demonstrated beneficial effects on fatigue and sleep disturbance. Music interventions have demonstrated efficacy for pain and fatigue. No trials were found that tested the mind-body interventions specifically for the pain-fatigue-sleep disturbance symptom cluster.Conclusion Efficacy studies are needed to test the impact of relaxation, imagery/hypnosis, CBT/CST, meditation, and music interventions in persons with cancer experiencing concurrent pain, fatigue, and sleep disturbance. These mind-body interventions could help patients manage all the symptoms in the cluster with a single treatment strategy.
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“Meta-analysis confirms that psychological interventions such as cognitive behavioral therapy (CBT) are effective in reducing physical symptoms across the cancer continuum into survivorship [15].”
From Acceptance and commitment therapy in adult cancer survivors: a systematic review and conceptual model (2021) · cites this paper as [15]
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Cites
The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research
Buysse, D. J., Reynolds, C. F., Monk, T. H., Berman, S. R., & Kupfer, D. J. (1989) · Psychiatry Research · doi:10.1016/0165-1781(89)90047-4 · Cited by 35,234
Aaronson, N. K., Ahmedzai, S., Bergman, B., Bullinger, M., Cull, A., Duez, N. J., Filiberti, A., Flechtner, H., Fleishman, S. B., Haes, J. C. J. M. D., et al. (1993) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/85.5.365 · Cited by 16,005
Smets, E. M. A., Garssen, B., Bonke, B., & de Haes, J. C. J. M. (1995) · Journal of Psychosomatic Research · doi:10.1016/0022-3999(94)00125-o · Cited by 3,622 · cited 2×
“Instruments that most frequently detected changes in fatigue included the visual analog scale, the fatigue, and vigor subscales from the Profile of Mood States,(94) and the Multidimensional Fatigue Inventory.(95) Measures most frequently sensitive to the effects of mind-body interventions on sleep disturbance included…”
MethodMcNair, D. M. (1992) · Medical Entomology and Zoology · Cited by 2,527
(1993) · Medical Entomology and Zoology · Cited by 2,324
Prevalence of pain in patients with cancer: a systematic review of the past 40 years
van den Beuken-van Everdingen, M. H. J., de Rijke, J. M., Kessels, A. G., Schouten, H. C., van Kleef, M., & Patijn, J. (2007) · Annals of Oncology · doi:10.1093/annonc/mdm056 · Cited by 1,923 · cited 1×
“Pain is reported by 59% of persons receiving anticancer treatment and 64% of those with advanced, metastatic, or terminal disease.(8) Fatigue, the most common symptom experienced by all the persons with cancer, impacts more than 75% of patients.”
BackgroundCarmody, J., & Baer, R. A. (2008) · Journal of Behavioral Medicine · doi:10.1007/s10865-007-9130-7 · Cited by 1,823 · cited 1×
“Some MBSR techniques include training in meditative exercises such as gentle yoga poses to help bring about the meditative state.(76) Symptoms such as pain, fatigue, and sleep disturbance may be modified through meditation by focusing attention away from the symptom experience, by focusing on strengths and positive th…”
BackgroundSerlin, R. C., Mendoza, T. R., Nakamura, Y., Edwards, K. R., & Cleeland, C. S. (1995) · Pain · doi:10.1016/0304-3959(94)00178-h · Cited by 1,493
Impact of Cancer-Related Fatigue on the Lives of Patients: New Findings From the Fatigue Coalition
Curt, G. A., Breitbart, W., Cella, D., Groopman, J. E., Horning, S. J., Itri, L. M., Johnson, D. H., Miaskowski, C., Scherr, S. L., Portenoy, R. K., et al. (2000) · The Oncologist · doi:10.1634/theoncologist.5-5-353 · Cited by 1,248
Advancing the science of symptom management
Dodd, M. J., Janson, S. L., Facione, N. C., Faucett, J. A., Froelicher, E. S., Humphreys, J. C., Lee, K. A., Miaskowski, C. A., Puntillo, K., Rankin, S. H., et al. (2001) · Journal of Advanced Nursing · doi:10.1046/j.1365-2648.2001.01697.x · Cited by 1,104 · cited 1×
“Symptom clusters are defined as combinations of two or more cooccurring symptoms that are related to each other and that are independent of other symptoms or symptom clusters.(3,4) Symptoms within the cluster may share the same etiology, but are not required to do so.”
Background
Research works printed but not linked: 3
- Breitbart, 2007, Psychiatric aspects of cancer pain management, Prim Psychiatry, 14, 81
- Cholburi, 2004, Effects of music therapy on anxiety and pain in cancer patients, Thai J Nurs Res, 8, 173
- Aaronson, 1993, The EORTC-QLQ-30: a quality of life instrument for use in international clinical trials in oncology, Qual Life Res, 2, 51
Cited by
Sorted by citations
Items 101–200 of 228
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Eaton, L. H., & Hulett, J. M. (2019) · Seminars in Oncology Nursing · doi:10.1016/j.soncn.2019.04.005 · Cited by 22
HIV Symptom Clusters are Similar Using the Dimensions of Symptom Occurrence and Distress
Wilson, N., Hoffman, T. J., Heath, S. L., Saag, M. S., & Miaskowski, C. A. (2022) · Journal of Pain and Symptom Management · doi:10.1016/j.jpainsymman.2022.02.337 · Cited by 19
Mercadié, L., Mick, G., Guétin, S., & Bigand, E. (2015) · Pain Management Nursing · doi:10.1016/j.pmn.2015.01.005 · Cited by 20
Chen, E., Nguyen, J., Cramarossa, G., Khan, L., Zhang, L., Tsao, M. N., Danjoux, C. E., Barnes, E. A., Sahgal, A., Holden, L., et al. (2011) · Palliative Medicine · doi:10.1177/0269216311420197 · Cited by 19
Celia, G., Cavicchiolo, E., Girelli, L., Limone, P., & Cozzolino, M. (2021) · Counselling and Psychotherapy Research · doi:10.1002/capr.12512 · Cited by 25
Cancer Patients’ and Survivors’ Perceptions of the Calm App: Cross-Sectional Descriptive Study
Huberty, J., Puzia, M., Eckert, R., & Larkey, L. (2020) · JMIR Cancer · doi:10.2196/16926 · Cited by 18
“Findings indicate that mindfulness-based interventions can improve mood, attitude toward one’s ability to cope with pain, fatigue, sleep disturbance, and anxiety related to cancer symptoms [7].”
BackgroundBAHÇELİ, P. Z., Arslan, S., & İlik, Y. (2021) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2021.101518 · Cited by 17
Doorley, J. D., Greenberg, J., Stauder, M. J., & Vranceanu, A. (2021) · Mindfulness · doi:10.1007/s12671-021-01729-y · Cited by 15
Grégoire, C., Faymonville, M.-E., Vanhaudenhuyse, A., Charland-Verville, V., Jerusalem, G., & Bragard, I. (2018) · BMC Cancer · doi:10.1186/s12885-018-5046-6 · Cited by 14
Xiao, W., Chan, C. W. H., Xiao, J., Wong, C. L., & Chow, K. M. (2021) · Asia-Pacific Journal of Oncology Nursing · doi:10.4103/apjon.apjon-2141 · Cited by 14
“Managing a symptom cluster as a whole, rather than treating single symptoms, could be more efficient and effective.([14,17,18]) A previous cross‐sectional study (n = 130) conducted by our research team identified the nutrition impact symptom cluster experienced by NPC patients during RT.”
Spyridonis, F., Grønli, T., Hansen, J., & Ghinea, G. (2012) · Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) · doi:10.1109/embc.2012.6346462 · Cited by 13
“Finally, VR technology has also been well-reported by [9, 10, 11] in a series of studies to be an effective aid in reducing pain through hypnosis, as well as shown to decrease pain in persons with cancer [12, 13, 14].”
BackgroundThe Use of Comfort Kits to Optimize Adult Cancer Pain Management
Blackburn, L. M., Abel, S., Green, L., Johnson, K., & Panda, S. (2018) · Pain Management Nursing · doi:10.1016/j.pmn.2018.01.004 · Cited by 13
“Currently, many oncology nurses are unsure of their role in use of CAM because of roadblocks such as the lack of a supportive clinical environment, lack of education about CAM, lack of supplies, and lack of nursing guidelines for safe use (Blackburn et al., 2017; Klafke et al., 2016; Kwekkeboom et al., 2010; Running &…”
BackgroundColloca, G. A., Venturino, A., Governato, I., & Checcaglini, F. (2015) · Clinical Genitourinary Cancer · doi:10.1016/j.clgc.2015.07.023 · Cited by 13
Symptom Clusters in Survivorship and Their Impact on Ability to Work among Cancer Survivors
Fardell, J. E., Tan, S. Y., Kerin‐Ayres, K., Dhillon, H. M., & Vardy, J. L. (2023) · Cancers · doi:10.3390/cancers15215119 · Cited by 12
“…cancers receiving treatment, a two week audio-recorded and delivered training program of twelve relaxation, imagery, or distraction exercises reduced the severity of the pain, fatigue, and sleep disturbance symptom cluster at two weeks post intervention, compared to a waitlist control group [35].”
BackgroundInfluentialLi, M., Yao, L.-Q., Liu, X., Tan, J.-Y. B., & Wang, T. (2024) · Asia-Pacific Journal of Oncology Nursing · doi:10.1016/j.apjon.2024.100380 · Cited by 12
Attitudes of Patients Toward Adoption of 3D Technology in Pain Assessment: Qualitative Perspective
Spyridonis, F., Ghinea, G., & Frank, A. O. (2013) · Journal of Medical Internet Research · doi:10.2196/jmir.2427 · Cited by 12
Canella, C., Mikolasek, M., Rostock, M., Beyer, J., Gückenberger, M., Jenewein, J., Linka, E., Six, C., Stoll, S., Stupp, R., et al. (2017) · Integrative Cancer Therapies · doi:10.1177/1534735417740629 · Cited by 16
Sleep Disturbances in Acutely Ill Patients with Cancer
Matthews, E. E., Tanner, J. M., & Dumont, N. A. (2016) · Critical Care Nursing Clinics of North America · doi:10.1016/j.cnc.2016.02.006 · Cited by 12
Dewi, E. U., Nursalam, N., Mahmudah, M., & Yunitasari, E. (2023) · Journal of Public Health Research · doi:10.1177/22799036221146901 · Cited by 14
Huberty, J., Bhuiyan, N., Neher, T. L., Joeman, L., Mesa, R. A., & Larkey, L. (2022) · JMIR Formative Research · doi:10.2196/32458 · Cited by 9
“Meditation has been shown to improve symptoms such as pain, sleep disturbance, anxiety, and fatigue in cancer patients and survivors [4-7].”
BackgroundL’art-thérapie en soins palliatifs : une étude qualitative
Rhondali, W., Chirac, A., & Filbet, M. (2013) · Médecine Palliative · doi:10.1016/j.medpal.2012.11.002 · Cited by 10
Virtual Reality Combined with Mind-Body Therapies for the Management of Pain: A Scoping Review
Louras, M., Vanhaudenhuyse, A., Panda, R., Rousseaux, F., Carella, M., Gosseries, O., Bonhomme, V. L., Faymonville, M.-É., & Bicego, A. (2024) · International Journal of Clinical and Experimental Hypnosis · doi:10.1080/00207144.2024.2391365 · Cited by 10
“Still in patients with cancer, Kwekkeboom et al. (2010) categorized as relaxation any technique which is designed to elicit a state of relative freedom from mental and/or physical tension, and included progressive muscle relaxation as well, jaw relaxation, focused breathing, or abdominal breathing.”
InfluentialZhou, Z., Yang, Y., Sun, J., Dong, Y., Zhu, M., Wang, T., & Teng, L. (2024) · Supportive Care in Cancer · doi:10.1007/s00520-024-09032-x · Cited by 9
“The pain-fatigue-sleep disturbance symptom cluster (PFS) is the most extensively documented and studied symptom cluster [9].”
Krueger, E., Seçinti, E., Wu, W., Hanna, N. H., Durm, G. A., Einhorn, L. H., Jalal, S. I., & Mosher, C. E. (2021) · Supportive Care in Cancer · doi:10.1007/s00520-021-06159-z · Cited by 9
Gruber, H., Rose, J.-P., Mannheim, E. G., & Weis, J. (2011) · Musiktherapeutische Umschau · doi:10.13109/muum.2011.32.3.206 · Cited by 9
The Effect of Five-Finger Relaxation Technique to The Sleep Quality of Breast Cancer Patients
Dewi, R., Rahayuwati, L., & Kurniawan, T. (2018) · Jurnal Keperawatan Padjadjaran · doi:10.24198/jkp.v6i2.739 · Cited by 9
Effect of Muscle Relaxation on Hemodialysis Patients’ Pain
blouchi, T., Kianmehr, M., tavakolizade, J., Basirimoghadam, M., & Biabani, F. (2015) · Quarterly of Horizon of Medical Sciences · doi:10.18869/acadpub.hms.21.2.75 · Cited by 9
Anxiety sensitivity and fatigue severity among adults with chronic low back pain
Kauffman, B. Y., Manning, K. F., Rogers, A. H., Matoska, C. T., & Zvolensky, M. J. (2021) · Fatigue Biomedicine Health & Behavior · doi:10.1080/21641846.2021.2009684 · Cited by 8
“may contribute to greater sensitivity to pain [13], perpetuating the maintenance of CLBP over time.”
BackgroundInfluentialPain and Spirituality Among Women With Advanced Breast Cancer
Miller, M. E., Greenwalt, K., Lehto, R. H., Wu, H.-S., Moser, J. S., & Wyatt, G. K. (2021) · Cancer Care Research Online · doi:10.1097/cr9.0000000000000001 · Cited by 9
Tanrıverdi, Ö., & Aydemir, N. F. (2013) · Asian Pacific Journal of Cancer Prevention · doi:10.7314/apjcp.2013.14.11.6537 · Cited by 8
“In previous studies, patients listened music which they choose and love and also this music was relaxing and be accepted, several authors recommend individual music therapy (Huang et al., 2010; Kwekkeboom et al., 2010; Li et al., 2012).”
BackgroundKirsch, J. L., Robinson, M. E., McCrae, C. S., Kacel, E. L., Wong, S. S., Patidar, S. M., Sannes, T. S., Garey, S. L., Castagno, J. C., & Pereira, D. B. (2018) · Pain Medicine · doi:10.1093/pm/pny236 · Cited by 8
“The use of imagery and coping skills training has also been found to reduce sleep disturbances and pain in cancer patients [45].”
BackgroundWang, S., Xu, W., Sun, A., Zhang, Z., Zhang, Y., Zhu, Y., & Wan, H. (2025) · Psycho-Oncology · doi:10.1002/pon.70062 · Cited by 7
“When they occur simultaneously, their negative impact on patients can be greater than when these symptoms occur individually [29].”
Consensus statement on chronic pain treatment in cancer survivors
Mamiya, K., Iida, H., Iseki, M., Yamaguch, S., Yonekura, H., Ueno, H., Kosugi, T., Sasara, T., Takao, Y., Takasusuki, T., et al. (2024) · Journal of Anesthesia · doi:10.1007/s00540-024-03427-0 · Cited by 7
Nguyen, L. T., Yates, P. M., Annoussamy, L. C., & Trung, T. Q. (2016) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2016-2476 · Cited by 8
“Similarly, the second review particularly included mind-body treatment for pain, fatigue and sleep disturbance.(86) The third review included different interventions for various multiple symptoms.”
BackgroundTHE EFFECT OF PROGRESSIVE RELAXATION THERAPY ON ELDERLY WITH INSOMNIA
Sutrisno, S., Herawati, V. D., & Aryani, A. (2022) · Jurnal Keperawatan Respati Yogyakarta · doi:10.35842/jkry.v9i2.646 · Cited by 7
Cancer-related fatigue: Systematic reviews and meta-analyses of mind–body intervention
Anshasi, H. A., & Ahmad, M. M. (2020) · Palliative & Supportive Care · doi:10.1017/s1478951520001194 · Cited by 6
“Two articles were excluded because one of them was not a systematic review (Kwekkeboom et al., 2010), and the other one did not review trials on CRF (Ulrichsen et al.”
BackgroundPsychosocial and Patient Support Services in Comprehensive Cancer Centers
Chakraborty, R., Majhail, N. S., & Abraham, J. (2021) · Springer eBooks · doi:10.1007/978-3-030-82052-7_11 · Cited by 9
Safety and Side Effects of Non-pharmacological Interventions as a Therapy for Cancer
Williams, A., Bulsara, C., & Petterson, A. S. (2012) · Evidence-based anticancer complementary and alternative medicine · doi:10.1007/978-94-007-5833-9_10 · Cited by 6
End-of-life care: Beliefs, attitudes, and experiences of Iranian physicians
Naghavi‐Behzad, M., Jabbari, H., Piri, R., Bakhshian, F., Mohit, B., Mohammadi, S., & Mahmoudzadeh, N. (2018) · Indian Journal of Palliative Care · doi:10.4103/ijpc.ijpc_74_18 · Cited by 6
“[17] These services include: physicians’ services; medical instruments; nursing care; drugs; the services of homemakers and home health helpers; physical, speech, and occupational therapy.[18-23] The Context: Most of the patients suffering from cancer are diagnosed at late stages of cancer, which curative intervention…”
BackgroundRaj, K. S., & Pillai, R. R. (2021) · Journal of South Asian Federation of Obstetrics and Gynaecology · doi:10.5005/jp-journals-10006-1875 · Cited by 6
“J South Asian Feder Obst Gynae 2019;12(3):70 –73.”
BackgroundZhang, H., Li, S., Yuan, M., Liu, J., Fan, H., & Li, S. (2025) · Supportive Care in Cancer · doi:10.1007/s00520-024-09141-7 · Cited by 5
“For instance, several physical and cognitive-behavioral interventions have the potential efficacy to alleviate the severity of some of the symptom experienced by cancer patients during and after treatment, particularly pain, fatigue, and sleep disturbance [50, 51].”
Treatment of Fatigue and Sleep Disorders in Cancer Patients
Goforth, H. W., & Davis, M. P. (2014) · The Cancer Journal · doi:10.1097/ppo.0000000000000070 · Cited by 5
“Epidemiologically, there is a close association between fatigue and insomnia such that they are considered within a symptom cluster.(1,2) Second, there is an observed desynchronization of circadian rhythms among individuals with cancer and survivors who have cancer-related fatigue.”
BackgroundKarami, M., Rafezi, Z., Motavalli, M. S., & Ayadi, N. (2021) · Jundishapur Journal of Chronic Disease Care · doi:10.5812/jjcdc.118106 · Cited by 5
Complementary and Alternative Medicine
White, J. D. (2014) · Elsevier eBooks · doi:10.1016/b978-1-4557-2865-7.00033-3 · Cited by 5
Feasibility of Attention Restoration Theory-Driven Hypnotherapy for Fatigue in Cancer Survivors
Elkins, G. R., Rhodes, J. R., Biggs, M. L., Zimmerman, K., Williams, W., Arring, N., & Barton, D. L. (2021) · International Journal of Clinical and Experimental Hypnosis · doi:10.1080/00207144.2021.1877088 · Cited by 5
“Findings suggested that there is some evidence to support the use of imagery/hypnosis interventions for all three symptoms, and more specifically, hypnosis-oriented interventions may be of benefit in reducing CRF (Kwekkeboom et al., 2010; Mendoza et al., 2017; Montgomery et al., 2014).”
BackgroundQUALIDADE DO SONO E CLUSTER DE SINTOMAS EM PACIENTES COM CÂNCER EM TRATAMENTO QUIMIOTERÁPICO
Nunes, N. A. H., & Ceolim, M. F. (2019) · Cogitare Enfermagem · doi:10.5380/ce.v24i0.58046 · Cited by 4
“Estudos para a melhoria do cluster de sintomas sono, dor e fadiga devem ser realizados, pois o sono é um preditor de morbidade e mortalidade(4).”
BackgroundBiological Effects of Music in Cancer Patients: Contributing to an Evidence-Based Practice
Taets, G. G. D. C. C., Fernandes, C., Torres, L. D. C., & Taets, C. M. C. (2020) · International Journal of Sciences · doi:10.18483/ijsci.2302 · Cited by 4
“25 An American study confirmed these outcomes in pediatric patients as well.(26)”
BackgroundKirvin-Quamme, A., Rumble, M. E., Cadmus‐Bertram, L., Juckett, M., Rathouz, P. J., Schell, G., Callander, N. S., Hematti, P., & Costanzo, E. S. (2022) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2022.100938 · Cited by 4
“The translational implication is that a single intervention targeting this cluster may be an efficient and effective means for improving multiple quality of life concerns [13].”
BackgroundThe Effect of Non-Pharmacological Self-Care Training on Pain Control in Cesarean Section Surgery
Zarei, M. R., Mamashli, L., Khachian, A., Bozorgnajad, M., & Ardebili, F. M. (2020) · Journal of Health and Care · doi:10.29252/jhc.22.1.34 · Cited by 4
Distress among cancer patients attending rehabilitation in the community
Kuo, A. (2021) · Supportive Care in Cancer · doi:10.1007/s00520-021-06422-3 · Cited by 4
A Short Term, Structured, Psychoeducational Intervention for Newly Diagnosed Cancer Patients
Fawzy, F. I., & Fawzy, N. W. (2011) · doi:10.1002/9780470975176.ch11 · Cited by 4
Ferretti, M., Lowery Walker, K., Bires, J., & BrintzenhofeSzoc, K. (2024) · Journal of Psychosocial Oncology · doi:10.1080/07347332.2023.2238263 · Cited by 4
“13,14 Mind-body techniques have also been found to lessen negative physical and emotional outcomes.”
BackgroundPersonalized therapy as a new strategy for the treatment of cancer pain
Abuzarova, G. R., Alekseeva, G. S., Владимировна, Н. Д., Рашитовна, С. Р., Бычкова, Н. М., & Kuznetsov, S. V. (2021) · Russian Journal of Pain · doi:10.17116/pain20211901146 · Cited by 3
Nonpharmacological Interventions in the Treatment of Cancer-Related Fatigue
Lü, L., Dai, H., Jomeen, J., Puts, M. T. E., & Tian, L. (2024) · Clinical Cancer Investigation Journal · doi:10.51847/jujcxoohhg · Cited by 3
“[22] reviewed 43 studies conducted on the effect of mind-body methods on reducing cancer pain symptoms, cancer-related fatigue, and sleep disturbance.”
BackgroundIsley, S., Johnson, E., Corrick, S., Hyde, A. M., Vandermeer, B., Dolgoy, N. D., Tabert, N., Pituskin, E., & Tandon, P. (2025) · PLOS Digital Health · doi:10.1371/journal.pdig.0000878 · Cited by 3
Gamus, D., Kedar, A., & Kleinhauz, M. (2012) · Progress in Palliative Care · doi:10.1179/1743291x12y.0000000025 · Cited by 3
Nicolussi, A. C., Cardozo, F. M. C., Avelar, J. M. D. P., & Sawada, N. O. (2018) · Revista de Enfermagem e Atenção à Saúde · doi:10.18554/reas.v7i2.2130 · Cited by 4
Lou, Y. (2011) · Faculty of Health; Institute of Health and Biomedical Innovation · Cited by 3
Pain and Frailty in Childhood Cancer Survivors: A Narrative Review
Papini, C., Sodhi, J. K., Argenbright, C. M., Ness, K. K., & Brinkman, T. M. (2024) · Current Oncology · doi:10.3390/curroncol32010022 · Cited by 3
“Combinations of these approaches, which can also be implemented in groups to address social aspects of pain (e.g., social support), are available in many pain management programs [127–131].”
InfluentialBadr, E. A., El-Gizawy, H. H., & Mohamed, S. M. (2026) · Journal of Pediatric Nursing · doi:10.1016/j.pedn.2026.02.030 · Cited by 2
Évaluation de la pratique de l’hypnose en soins palliatifs
Quintini, D., Fichaux, M., Surdej, F., Espanet, N., & Salas, S. (2018) · Recherche en soins infirmiers · doi:10.3917/rsi.133.0085 · Cited by 3
How Theory Can Help Facilitate Implementing Relaxation as a Complementary Pain Management Approach
Eaton, L. H., Hulett, J. M., Langford, D. J., & Doorenbos, A. Z. (2019) · Pain Management Nursing · doi:10.1016/j.pmn.2018.12.008 · Cited by 4
Integrative chronic pain management: a narrative review
Halma, M. T. J., Marik, P. E., Saleeby, Y. M., & Tuszyński, J. A. (2025) · Journal of Multiscale Neuroscience · doi:10.56280/1702545951 · Cited by 1
Therapeutic potential of yoga nidra for chemo brain: a complementary and integrative perspective
Sahu, S. K., & Pradhan, A. K. (2025) · Psychoradiology · doi:10.1093/psyrad/kkaf020 · Cited by 2
“Studies have re-ported notable reductions in perceived stress, improvements in mood, and enhanced sleep quality among cancer patients practicing YN, highlighting its potential as a multimodal supportive care strategy (Giridharan, 2024 ; Kwekkeboom et al. , 2010 ).”
A critical review of non-pharmacological cancer pain management in multidisciplinary approach
Parameswari, S., Sunilson, J. A. J., Raja, & Sujeetha, B. (2021) · AIP conference proceedings · doi:10.1063/5.0058322 · Cited by 2
Pain Management in Cancer Patients Who Are Registered in Public Health Centers
Choi, S. Y., Chang, K. O., Park, M. N., & Ryu, E. (2012) · Asian Oncology Nursing · doi:10.5388/aon.2012.12.1.77 · Cited by 2
Absolon, N. A., Truant, T. L. O., Balneaves, L. G., Goodwin, F., Cashman, R. L., Wong, M., & Witmans, M. (2014) · Canadian Oncology Nursing Journal · doi:10.5737/1181912x243154159 · Cited by 2
Sleep Quality and its Associated Factors in Iranian Patients with Breast Cancer
Habibi, F., Jazi, M. S. H., Hemati, S., & Gholamrezaei, A. (2016) · International journal of body, mind and culture · doi:10.22122/ijbmc.v3i2.54 · Cited by 2
Gamus, D. (2016) · Focus on Alternative and Complementary Therapies · doi:10.1111/fct.12266 · Cited by 2
Guide imagery and music (GIM) untuk menurunkan kecemasan kompetitif pada atlet sebelum bertanding
Amin, M. F. A., & Iswinarti, I. (2020) · Jurnal Ilmiah Psikologi Terapan · doi:10.22219/jipt.v8i1.7352 · Cited by 2
Complementary and Alternative Medicine
White, J. D. (2020) · Elsevier eBooks · doi:10.1016/b978-0-323-47674-4.00031-1 · Cited by 3
Cassileth, B. R. (2011) · Psycho-Oncologie · doi:10.1007/s11839-011-0325-3 · Cited by 2
Vuttanon, N., Finnegan, L., Lojanapiwat, B., Sittisombut, S., Meechumnan, C., & Dhatsuwan, J. (2019) · Srinagarind Medical Journal-ศรีนครินทร์เวชสาร · Cited by 2
Paice, J. A. (2016) · Oxford University Press eBooks · doi:10.1093/med/9780190204747.003.0023 · Cited by 2
Placer García, L. D., Torrijos Zarcero, M., Rocamora González, C., Muñoz San José, A., & Palao Tarrero, Á. I. (2025) · Psicooncologia · doi:10.5209/psic.102233 · Cited by 1
Cramarossa (2011) · World Journal of Oncology · doi:10.4021/wjon386w · Cited by 1
“Patients with bone metastases often experience concurrent symptoms that simultaneously influence their quality of life in a multiplicative manner [2].”
BackgroundCho, Y.-N., & Kim, I.-J. (2015) · The Korean Journal of Rehabilitation Nursing · doi:10.7587/kjrehn.2015.128 · Cited by 1
“Also these results confirmed the reduction of pain and sleep disturbance is closely related with the production of relaxation response (Kwekkeboom et al., 2010).”
BackgroundLee, N.-G., & Kim, B.-K. (2023) · Healthcare · doi:10.3390/healthcare11070956 · Cited by 1
“Therefore, mind–body interventions are used as complementary therapy strategies, which are nonpharmaceutical, inexpensive, and noninvasive methods with relatively few side effects and may provide beneficial effects when added to traditional treatments [11].”
BackgroundKomorbidität von chronischem Schmerz und Fatigue
Hasenbring, M. I., Levenig, C. G., & Titze, C. (2025) · Der Schmerz · doi:10.1007/s00482-025-00898-2 · Cited by 1
Boyang, D., Jiazhen, C., Liu, Y., Xuelian, C., Mahemuti, N., Wei, W., & Yumei, M. (2026) · Brain Behavior and Immunity Integrative · doi:10.1016/j.bbii.2026.100181 · Cited by 1
Complementary and Alternative Medicine
Whitehouse, P. J. (2009) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2009.0371 · Cited by 1
Absolon, N. A., Truant, T. L. O., Balneaves, L. G., Goodwin, F., Cashman, R. L., Wong, M., & Witmans, M. (2014) · PubMed · Cited by 1
Clinical Hypnosis for Symptom Management of Cancer Patients in Palliative Care
Kabalak, A. A. (2014) · Journal of Palliative Care & Medicine · doi:10.4172/2165-7386.1000181 · Cited by 1
“Clinical hypnosis is very effective in enhancing the cancer patient’s coping skills, managing emotional stress and anxiety, reducing pain, nausea, fatigue, hot flushes, breathlessness, sleep dysfunction, and symptoms associated with radiation and chemotherapy [6-8].”
BackgroundSridhar, S. (2017) · Elsevier eBooks · doi:10.1016/b978-0-323-35868-2.00081-5 · Cited by 1
Supportive and Palliative Care for Genitourinary Malignancies
Wulff-Burchfield, E. M. (2022) · Springer eBooks · doi:10.1007/978-3-030-89891-5_2 · Cited by 1
Strouse, T. B., & Bursch, B. (2018) · Hematology/Oncology Clinics of North America · doi:10.1016/j.hoc.2018.01.010 · Cited by 1
Muscle Mass, Cachexia, and Health-Related Quality of Life in Patients with Hematologic Malignancies
Ishii, S., Hirota, K., & Nakano, J. (2022) · Springer eBooks · doi:10.1007/978-981-19-6710-8_5 · Cited by 1
The Effect of Back Massage Applied to Palliative Care Patients on Sleep Quality and Pain
DURMAZ, H., & CEBECİ, S. P. (2023) · OSMANGAZİ JOURNAL OF MEDICINE · doi:10.20515/otd.1361722 · Cited by 1
Post‐White, J., & Ndao, D. H. (2012) · Pediatric oncology · doi:10.1007/978-3-642-04201-0_7 · Cited by 2
Kimball, B. C., Geller, G., Warsame, R. M., Kumbamu, A., Jatoi, A., Koenig, B. A., & Tilburt, J. C. (2018) · The Oncologist · doi:10.1634/theoncologist.2017-0518 · Cited by 1
Ishii, S., Natsuzako, A., Fukushima, T., Kozu, R., Miyata, N., & Nakano, J. (2021) · Palliative Care Research · doi:10.2512/jspm.16.123 · Cited by 1
Kurniawati, D. M., & Bungsu, P. P. (2021) · International Journal of Health and Medical Sciences · doi:10.20469/ijhms.7.30003 · Cited by 1
Paice, J. A. (2019) · Oxford University Press eBooks · doi:10.1093/med/9780190862374.003.0009 · Cited by 1
Supportive Care and End of Life
Grossman, M. (2022) · Springer eBooks · doi:10.1007/978-3-031-06101-1_18 · Cited by 1
Hwang, M. H., & Bunt, L. (2020) · Approaches An Interdisciplinary Journal of Music Therapy · doi:10.56883/aijmt.2022.130 · Cited by 1
Integrative Medicine for Cancer Patients
Chun, M. (2010) · Hanyang Medical Reviews · doi:10.7599/hmr.2010.30.2.126
Cramarossa (2012) · World Journal of Oncology · doi:10.4021/wjon394w
“These patients often experience multiple symptoms at one time that concurrently influence their quality of life in a multiplicative manner [2].”
BackgroundDisentangling the Evidence: The Efficacy of Meditation in People with Cancer
Black, D. A., Wilson, L. A., & Manocha, R. (2011) · IMPERIAL COLLEGE PRESS eBooks · doi:10.1142/9781848165571_0006
Complementary and alternative therapies in cancer/integrative oncology
MacDonald, S. E., & Oneschuk, D. (2012) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780199694143.003.0151
A Multi Platform Pain Assessment Tool using Bespoke Gaming Sensors
Spyridonis, F., Grønli, T., Paraskevopoulos, I. T., & Ghinea, G. (2016) · International Conference on PErvasive Technologies Related to Assistive Environments (PETRA) · doi:10.1145/2910674.2910701
“Studies also demonstrated that VR could be effective in decreasing pain in persons with cancer [9].”
Background
Metadata
- Authors
- Kwekkeboom, K. L., Cherwin, C. H., Lee, J. W., & Wanta, B.
- Affiliations
- University of Wisconsin–Madison (US)
- Corresponding author
- Kwekkeboom, Kristine L.
- Venue
- Journal of Pain and Symptom Management
- Publisher
- Elsevier BV
- Published
- 2010-01
- Volume
- 39
- Issue
- 1
- Pages
- 126-138
- ISSN
- 0885-3924 (ISSN-L)
- PMC
- PMC3084527
- OpenAlex
- W1971153042
- Cited by
- 228
- References
- 106
- Citations by year
- 2026: 7 · 2025: 9 · 2024: 9 · 2023: 11 · 2022: 14 · 2021: 21 · 2020: 16 · 2019: 13 · 2018: 18 · 2017: 14 · 2016: 12 · 2015: 13 · 2014: 17 · 2013: 16 · 2012: 19
- FWCI
- 1.11
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of Pain and Symptom Management (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute of Nursing Research (P20NR008987)
- Topics
- Health Sciences › Medicine › Oncology › Cancer survivorship and care
- Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
- Health Sciences › Medicine › Complementary and alternative medicine › Complementary and Alternative Medicine Studies
- Keywords
- mind-body interventions, cancer pain, cancer-related fatigue, sleep disorders, symptom clusters, cognitive behavioral therapy, coping skills training, relaxation, meditation, music therapy, virtual reality, symptom management
- MeSH terms
- Fatigue, Humans, Neoplasms, Pain, Sleep Wake Disorders, Mind-Body Therapies, Pain Management
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