Cited by 241Mindfulness and Compassion InterventionsCancer survivorship and careReligion, Spirituality, and Psychology

Mindfulness-Based Cognitive Therapy for Psychological Distress, Fear of Cancer Recurrence, Fatigue, Spiritual Well-Being, and Quality of Life in Patients With Breast Cancer—A Randomized Controlled Trial

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Park, Sunre, Sato, Yasuko, Takita, Yuka, Tamura, Noriko, Ninomiya, Akira, Kosugi, Teppei, Sado, Mitsuhiro, Nakagawa, Atsuo +3 more·2020·Journal of Pain and Symptom Management

Abstract

Context Mindfulness-based interventions have been receiving growing attention in cancer care.Objectives The purpose of this randomized controlled trial is to examine the effectiveness of mindfulness-based cognitive therapy (MBCT) for psychological distress (anxiety and depression), fear of cancer recurrence (FCR), fatigue, spiritual well-being, and quality of life (QOL) in Japanese ambulatory patients with Stage I-III breast cancer.Methods A total of 74 patients were randomly assigned to either an eight-week MBCT intervention group (n = 38) or a wait-list control group (n = 36). The primary outcome was psychological distress, measured on Hospital Anxiety and Depression Scale. The secondary outcomes were FCR (Concerns About Recurrence Scale-overall anxiety subscale), fatigue (Brief Fatigue Inventory), spiritual well-being (Functional Assessment of Chronic Illness Therapy-Spiritual), QOL (Functional Assessment of Cancer Therapy-General), and mindfulness skills (Five Facet Mindfulness Questionnaire). The participants were assessed at baseline (T0), Week 8 (T1), and Week 12 (T2). The results were analyzed using a intention-to-treat linear mixed model.Results The participants in the MBCT group experienced significantly better outcomes in their psychological distress (Cohen's d = 1.17; P < 0.001), FCR (d = 0.43; P < 0.05), fatigue (d = 0.66; P < 0.01), spiritual well-being (d = 0.98; P < 0.001), and QOL (d = 0.79; P < 0.001) compared with the control group. The difference remained significant at T2 (four weeks after completion of the intervention).Conclusion MBCT was demonstrated to improve well-being that encompasses psychological, physical, and spiritual domains in Japanese patients with nonmetastatic breast cancer. The favorable effect was maintained up to four weeks after the completion of the intervention.

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Crossref · 10.1016/j.jpainsymman.2020.02.017

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  • In nonmetastatic Japanese participants, an 8-week course of Mindfulness-Based Cognitive Therapy (MBCT) resulted in significantly better outcomes in psychological distress, fatigue, spiritual well-being, and quality of life than wait-list control.

    “Park et al. found in a group of nonmetastatic, Japanese participants that those who were provided an 8-week course of Mindfulness-Based Cognitive Therapy (MBCT) had significantly better outcomes in psychological distress, fatigue, spiritual well-being, and quality of life than the study’s wait-list control group [25].”

    From Psychological Intervention and Breast Cancer (2024) · cites this paper as [25]

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Authors
Park, S., Sato, Y., Takita, Y., Tamura, N., Ninomiya, A., Kosugi, T., Sado, M., Nakagawa, A., Takahashi, M., Hayashida, T., & Fujisawa, D.
Affiliations
  • Keio University (JP)
  • Tokyo Medical Center (JP)
  • Tokyo Kasei University (JP)
Corresponding author
Park, Sunre
Venue
Journal of Pain and Symptom Management
Publisher
Elsevier BV
Published
2020-08
Volume
60
Issue
2
Pages
381-389
ISSN
0885-3924 (ISSN-L)
OpenAlex
W3007255206
Cited by
241
References
42
Citations by year
2026: 43 · 2025: 72 · 2024: 56 · 2023: 37 · 2022: 23 · 2021: 10
FWCI
6.99
Type
journal article
Language
en
Open access
Locations
  • Journal of Pain and Symptom Management (publishedVersion)
  • PubMed (publishedVersion)
  • Institutional Repositories DataBase (IRDB) (submittedVersion)
Funders
  • Keio Gijuku Academic Development Funds
  • Japan Society for the Promotion of Science (JP15K09875)
Topics
  • Social Sciences › Psychology › Clinical Psychology › Mindfulness and Compassion Interventions
  • Health Sciences › Medicine › Oncology › Cancer survivorship and care
  • Social Sciences › Health › Religion, Spirituality, and Psychology
Keywords
mindfulness-based cognitive therapy, breast cancer, psychological distress, anxiety, depression, fear of cancer recurrence, cancer-related fatigue, spiritual well-being, quality of life, mindfulness skills, Japanese patients, non-metastatic breast cancer
MeSH terms
Psychological Distress, Breast Neoplasms, Fatigue, Fear, Female, Humans, Neoplasm Recurrence, Local, Quality of Life, Cognitive Behavioral Therapy, Mindfulness

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