Comorbidities in pediatric patients with postural orthostatic tachycardia syndrome
Abstract
Objective To investigate the frequency of various nonorthostatic complaints in children with postural orthostatic tachycardia syndrome (POTS). Study design We used our autonomic laboratory database to identify all pediatric patients with traditionally defined POTS who had completed the Ohio Dysautonomia Survey (ODYSA). The responses of the patients to questions targeting various autonomic complaints, including syncope, gastrointestinal symptoms, sleep disturbances, headaches, urinary symptoms, chronic pain, and Raynaud-like symptoms, were collected and analyzed. Results A total of 53 pediatric patients completed the ODYSA questionnaire. The participants reported high frequencies of sleep abnormalities, chronic pain, Raynaud-like symptoms, and gastrointestinal abnormalities, with lower rates of headaches, syncope, and urinary complaints. Conclusions Our findings demonstrate the occurrence of various nonorthostatic symptoms in pediatric patients with POTS. These findings suggest the need for an interdisciplinary approach to the treatment and management of POTS, as well as for further investigation into the mechanisms that lead to the concurrent presentation of both orthostatic and nonorthostatic symptoms in these patients.
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Up to 30% of POTS patients may experience syncope, and these patients may have both NMS and POTS, because these disorders can occur together.
“However, up to 30% of POTS patients may experience syncope, and these patients may have both NMS and POTS, because these disorders can occur together (9,65).”
From Postural Orthostatic Tachycardia Syndrome (2019) · cites this paper as [65]
A frequently described comorbidity in POTS patients is migraine, as well as other chronic headache types.
“A frequently described comorbidity in POTS patients is migraine, as well as other chronic headache types (6,65,72,73).”
From Postural Orthostatic Tachycardia Syndrome (2019) · cites this paper as [65]
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- Authors
- Ojha, A., Chelimsky, T. C., & Chelimsky, G.
- Affiliations
- University Hospitals of Cleveland (US)
- University Hospitals Cleveland Medical Center (US)
- Rainbow Babies & Children's Hospital (US)
- Corresponding author
- Chelimsky, Gisela
- Venue
- The Journal of Pediatrics
- Publisher
- Elsevier BV
- Published
- 2011-01
- Volume
- 158
- Issue
- 1
- Pages
- 20-23
- ISSN
- 0022-3476 (ISSN-L)
- OpenAlex
- W2014762017
- Cited by
- 131
- References
- 4
- Citations by year
- 2026: 7 · 2025: 4 · 2024: 2 · 2023: 4 · 2022: 6 · 2021: 9 · 2020: 12 · 2019: 6 · 2018: 10 · 2017: 9 · 2016: 14 · 2015: 17 · 2014: 13 · 2013: 7 · 2012: 5
- FWCI
- 6.03
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- The Journal of Pediatrics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Health Sciences › Medicine › Neurology › Long-Term Effects of COVID-19
- Keywords
- postural orthostatic tachycardia syndrome, pediatric patients, comorbidities, autonomic dysfunction, syncope, gastrointestinal symptoms, sleep disorders, chronic pain, headache, urinary symptoms, multidisciplinary management
- MeSH terms
- Adolescent, Adult, Female, Humans, Male, Retrospective Studies, Postural Orthostatic Tachycardia Syndrome
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