Lichenic extracts and metabolites as UV filters
Abstract
Three lichen extracts and ten lichenic compounds have been screened for their photoprotective activities. The determination of their Sun Protection Factor (SPF) and Protection Factor-UVA (PF-UVA) values was done in vitro. Among them, a Lasallia pustulata extract and gyrophoric acid exhibited SPF values over 5, which is better than Homosalate (SPF≈4). Their photoprotective properties are only slightly modified after a 2-hours period of irradiation. Salazinic acid and L. pustulata presented characteristics of a UVA booster like the butyl-methoxydibenzoylmethane (Avobenzone) (PF-UVA≈2 vs. 2.8 for Avobenzone). Salazinic acid was a better anion superoxide scavenger than ascorbic acid and none of them exhibited a photosensitizing cytotoxicity by exposing them on HaCaT cells to UVA radiations (photo-irritancy factor PIF<5).
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Extracts of Lippia sericea, Cecropia obtusa, Acacia catechu, Brazilian bamboo, and Lasallia pustulata have high SPF values in formulations (SPF = 7-86), with Brazilian bamboo most promising at SPF 44 after irradiation.
“The other extracts revealed to possess a complex mixture of compounds, namely a high content of phenols [102,105] and polyphenols [103] and high SPF values in formulations (SPF = 7–86) [102,103,104,105,106], being the extract of Brazilian bamboo species the most promising with a SPF value of 44, after irradiation [105].”
From UV Filters: Challenges and Prospects (2022) · cites this paper as [106]
Gyrophoric acid is the major component of L. pustulata extract and is proposed as main responsible for its antioxidant and photoprotective activities.
“Considering L. pustulata extract, it was verified that gyrophoric acid (39) was the major component detected by HPLC, being proposed that this secondary metabolite should be the main responsible for the antioxidant and photoprotective activities [106].”
From UV Filters: Challenges and Prospects (2022) · cites this paper as [106]
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- Authors
- Lohézic-Le Dévéhat, F., Legouin, B., Couteau, C., Boustie, J., & Coiffard, L.
- Affiliations
- Université Européenne de Bretagne (FR)
- Université de Nantes (FR)
- Corresponding author
- Legouin, Béatrice
- Venue
- Journal of Photochemistry and Photobiology B: Biology
- Publisher
- Elsevier BV
- Published
- 2013-03
- Volume
- 120
- Pages
- 17-28
- ISSN
- 1011-1344 (ISSN-L)
- OpenAlex
- W1999989854
- Cited by
- 80
- References
- 40
- Citations by year
- 2025: 4 · 2024: 7 · 2023: 10 · 2022: 7 · 2021: 7 · 2020: 9 · 2019: 3 · 2018: 6 · 2017: 6 · 2016: 7 · 2015: 6 · 2014: 5 · 2013: 3
- FWCI
- 8.17
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Photochemistry and Photobiology B Biology (publishedVersion)
- PubMed (publishedVersion)
- HAL (submittedVersion)
- Topics
- Health Sciences › Medicine › Dermatology › Skin Protection and Aging
- Life Sciences › Agricultural and Biological Sciences › Ecology, Evolution, Behavior and Systematics › Lichen and fungal ecology
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › melanin and skin pigmentation
- Keywords
- lichen extracts, UV filters, photoprotection, sun protection factor, UVA protection factor, Lasallia pustulata, gyrophoric acid, salazinic acid, avobenzone, superoxide radical scavenging, HaCaT keratinocytes, UVA irradiation
- MeSH terms
- Antioxidants, Ascomycota, Benzoates, Benzofurans, Cell Line, Fumarates, Humans, Lactones, Salicylates, Ultraviolet Rays, Usnea, Sun Protection Factor
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