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Quantitative proteomic analysis of hepatocyte-secreted extracellular vesicles reveals candidate markers for liver toxicity
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“Various animal studies and in vitro models have identified changes in the metabolomic profile in the presence of DILI [13,16,22,23,24,25,26,27,28,29,30,31,32,33,34,35].”
From Metabolomic Analysis of Pediatric Patients with Idiosyncratic Drug-Induced Liver Injury According to the Updated RUCAM (2023) · cites this paper as [29]
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Absolute Quantification of Proteins by LCMSE
Silva, J. C., Gorenstein, M. V., Li, G.-Z., Vissers, J. P. C., & Geromanos, S. J. (2006) · Molecular & Cellular Proteomics · doi:10.1074/mcp.m500230-mcp200 · Cited by 1,529
Self-citationQuantitative mass spectrometry in proteomics: critical review update from 2007 to the present
Bantscheff, M., Lemeer, S., Savitski, M. M., & Kuster, B. (2012) · Analytical and Bioanalytical Chemistry · doi:10.1007/s00216-012-6203-4 · Cited by 801
Michalski, A., Cox, J., & Mann, M. (2011) · Journal of Proteome Research · doi:10.1021/pr101060v · Cited by 685
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Research works printed but not linked: 78
- Pierce, 2008, Eight-channel iTRAQ enables comparison of the activity of six leukemogenic tyrosine kinases, Mol Cell Proteomics, 7, 853, 10.1074/mcp.M700251-MCP200 · DOI
- Amanchy, 2005, Stable isotope labeling with amino acids in cell culture (SILAC) for studying dynamics of protein abundance and posttranslational modifications, Sci STKE, 267, l2
- Bonzon-Kulichenko, 2011, A robust method for quantitative high-throughput analysis of proteomes by 18O labeling, Mol Cell Proteomics, 10, 10.1074/mcp.M110.003335 · DOI
- Prokhorova, 2009, Stable isotope labeling by amino acids in cell culture (SILAC) and quantitative comparison of the membrane proteomes of self-renewing and differentiating human embryonic stem cells, Mol Cell Proteomics, 8, 959, 10.1074/mcp.M800287-MCP200 · DOI
- Lundberg, 2010, Defining the transcriptome and proteome in three functionally different human cell lines, Mol Syst Biol, 6, 450, 10.1038/msb.2010.106 · DOI · Paper page
- Liu, 2012, Integrative proteomics and tissue microarray profiling indicate the association between overexpressed serum proteins and non-small cell lung cancer, PLoS One, 7, e51748, 10.1371/journal.pone.0051748 · DOI
- Jahn, 2011, Peptide fingerprinting of Alzheimer's disease in cerebrospinal fluid: identification and prospective evaluation of new synaptic biomarkers, PLoS One, 6, e26540, 10.1371/journal.pone.0026540 · DOI
- Washburn, 2001, Large-scale analysis of the yeast proteome by multidimensional protein identification technology, Nat Biotechnol, 19, 242, 10.1038/85686 · DOI
- Li, 2005, A software suite for the generation and comparison of peptide arrays from sets of data collected by liquid chromatography−mass spectrometry, Mol Cell Proteomics, 4, 1328, 10.1074/mcp.M500141-MCP200 · DOI
- Wang, 2003, Quantification of proteins and metabolites by mass spectrometry without isotopic labeling or spiked standards, Anal Chem, 75, 4818, 10.1021/ac026468x · DOI
- Silva, 2006, Simultaneous qualitative and quantitative analysis of the Escherichia coli proteome, Mol Cell Proteomics, 5, 589, 10.1074/mcp.M500321-MCP200 · DOI
- Silva, 2005, Quantitative proteomic analysis by accurate mass retention time pairs, Anal Chem, 77, 2187, 10.1021/ac048455k · DOI
- Radulovic, 2004, Informatics platform for global proteomic profiling and biomarker discovery using liquid chromatography−tandem mass spectrometry, Mol Cell Proteomics, 3, 984, 10.1074/mcp.M400061-MCP200 · DOI
- Rodríguez-Suárez, 2013, The application of quantification techniques in proteomics for biomedical research, Mass Spectrom Rev, 32, 1, 10.1002/mas.21347 · DOI
- Simons, 2009, Exosomes—vesicular carriers for intercellular communication, Curr Opin Cell Biol, 21, 575, 10.1016/j.ceb.2009.03.007 · DOI
- Fevrier, 2004, Exosomes: endosomal-derived vesicles shipping extracellular messages, Curr Opin Cell Biol, 16, 415, 10.1016/j.ceb.2004.06.003 · DOI · Paper page
- Simons, 2009, Exosomes — vesicular carriers for intercellular communication, Curr Opin Cell Biol, 21, 575, 10.1016/j.ceb.2009.03.007 · DOI
- Gasser, 2003, Characterisation and properties of ectosomes released by human polymorphonuclear neutrophils, Exp Cell Res, 285, 243, 10.1016/S0014-4827(03)00055-7 · DOI
- Jimenez, 2003, Endothelial cells release phenotypically and quantitatively distinct microparticles in activation and apoptosis, Thromb Res, 109, 175, 10.1016/S0049-3848(03)00064-1 · DOI
- Almqvist, 2008, Serum-derived exosomes from antigen-fed mice prevent allergic sensitization in a model of allergic asthma, Immunology, 125, 21, 10.1111/j.1365-2567.2008.02812.x · DOI
- Al-Nedawi, 2008, Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells, Nat Cell Biol, 10, 619, 10.1038/ncb1725 · DOI
- Caby, 2005, Exosomal-like vesicles are present in human blood plasma, Int Immunol, 17, 879, 10.1093/intimm/dxh267 · DOI
- Piccin, 2007, Circulating microparticles: pathophysiology and clinical implications, Blood Rev, 21, 157, 10.1016/j.blre.2006.09.001 · DOI
- Shet, 2008, Characterizing blood microparticles: technical aspects and challenges, Vasc Health Risk Manag, 4, 769, 10.2147/VHRM.S955 · DOI
- Wubbolts, 2003, Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation, J Biol Chem, 278, 10963, 10.1074/jbc.M207550200 · DOI
- Cocucci, 2009, Shedding microvesicles: artefacts no more, Trends Cell Biol, 19, 43, 10.1016/j.tcb.2008.11.003 · DOI · Paper page
- Simpson, 2009, Exosomes: proteomic insights and diagnostic potential, Expert Rev Proteomics, 6, 267, 10.1586/epr.09.17 · DOI
- Pap, 2009, Highlights of a new type of intercellular communication: microvesicle-based information transfer, Inflamm Res, 58, 1, 10.1007/s00011-008-8210-7 · DOI
- Wieckowski, 2006, Human tumor-derived vs dendritic cell-derived exosomes have distinct biologic roles and molecular profiles, Immunol Res, 36, 247, 10.1385/IR:36:1:247 · DOI
- Conde-Vancells, 2008, Characterization and comprehensive proteome profiling of exosomes secreted by hepatocytes, J Proteome Res, 7, 5157, 10.1021/pr8004887 · DOI
- Keppler, 1968, Experimental hepatitis induced by d-galactosamine, Exp Mol Pathol, 9, 279, 10.1016/0014-4800(68)90042-7 · DOI
- Han, 2002, Intestinal endotoxemia as a pathogenetic mechanism in liver failure, World J Gastroenterol, 8, 961, 10.3748/wjg.v8.i6.961 · DOI
- Kaido, 1997, Continuous hepatocyte growth factor supply prevents lipopolysaccharide-induced liver injury in rats, FEBS Lett, 411, 378, 10.1016/S0014-5793(97)00744-8 · DOI · Paper page
- Li, 2012, Yohimbine enhances protection of berberine against LPS-induced mouse lethality through multiple mechanisms, PLoS One, 7, e52863, 10.1371/journal.pone.0052863 · DOI
- Morrison, 1987, Endotoxins and disease mechanisms, Annu Rev Med, 38, 417, 10.1146/annurev.me.38.020187.002221 · DOI
- Ponzetti, 2010, Cyclic AMP-guanine exchange factor activation inhibits JNK-dependent lipopolysaccharide-induced apoptosis in rat hepatocytes, Hepat Med, 2010, 1
- Polsky-Fisher, 2006, Effect of cytochromes P450 chemical inhibitors and monoclonal antibodies on human liver microsomal esterase activity, Drug Metab Dispos, 34, 1361, 10.1124/dmd.106.009704 · DOI
- Seglen, 1976, Preparation of isolated rat liver cells, Methods Cell Biol, 13, 29, 10.1016/S0091-679X(08)61797-5 · DOI
- Gilar, 2005, Two-dimensional separation of peptides using RP-RP-HPLC system with different pH in first and second separation dimensions, J Sep Sci, 28, 1694, 10.1002/jssc.200500116 · DOI
- Silva, 2006, Absolute quantification of proteins by LCMSE: a virtue of parallel MS acquisition, Mol Cell Proteomics, 5, 144, 10.1074/mcp.M500230-MCP200 · DOI · Paper page
- Li, 2009, Database searching and accounting of multiplexed precursor and product ion spectra from the data independent analysis of simple and complex peptide mixtures, Proteomics, 9, 1696, 10.1002/pmic.200800564 · DOI
- Yu, 2011, Systematic proteomic analysis of human hepotacellular carcinoma cells reveals molecular pathways and networks involved in metastasis, Mol Biosyst, 7, 1908, 10.1039/c0mb00265h · DOI
- Pitarch, 2011, Prediction of the clinical outcome in invasive Candidiasis patients based on molecular fingerprints of five anti-Candida antibodies in serum, Mol Cell Proteomics, 10, 10.1074/mcp.M110.004010 · DOI
- Levin, 2011, The role of statistical power analysis in quantitative proteomics, Proteomics, 11, 2565, 10.1002/pmic.201100033 · DOI
- Banerjee, 2008, Identification of proteins to predict the molecular basis for the observed gender susceptibility in a rat model of alcoholic steatohepatitis by 2-D gel proteomics, Proteomics, 8, 4327, 10.1002/pmic.200700368 · DOI
- Lorenz, 2009, Proteomics reveals acute pro-inflammatory and protective responses in rat Kupffer cells and hepatocytes after chemical initiation of liver cancer and after LPS and IL-6, Proteomics Clin Appl, 3, 947, 10.1002/prca.200800173 · DOI
- Lu, 2012, Triptolide attenuate the oxidative stress induced by LPS/D-GalN in mice, J Cell Biochem, 113, 1022, 10.1002/jcb.23434 · DOI
- Lv, 2008, Senescence marker protein 30 in acute liver failure: validation of a mass spectrometry proteomics assay, BMC Gastroenterol, 8, 17, 10.1186/1471-230X-8-17 · DOI
- Rodriguez-Ariza, 2005, Altered protein expression and protein nitration pattern during d-galactosamine-induced cell death in human hepatocytes: a proteomic analysis, Liver Int, 25, 1259, 10.1111/j.1478-3231.2005.01172.x · DOI
- Sun, 2003, Evaluation of oxidative stress during apoptosis and necrosis caused by d-galactosamine in rat liver, Biochem Pharmacol, 65, 101, 10.1016/S0006-2952(02)01420-X · DOI
- Ramaiah, 2011, Preclinical safety assessment: current gaps, challenges, and approaches in identifying translatable biomarkers of drug-induced liver injury, Clin Lab Med, 31, 161, 10.1016/j.cll.2010.10.004 · DOI
- Ganz, 2011, Lipopolysaccharide induces and activates the Nalp3 inflammasome in the liver, World J Gastroenterol, 17, 4772, 10.3748/wjg.v17.i43.4772 · DOI
- Burdette, 2011, Hepatitis C virus activates interleukin-1beta via caspase-1-inflammasome complex, J Gen Virol, 93, 235, 10.1099/vir.0.034033-0 · DOI
- Csak, 2011, Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells, Hepatology, 54, 133, 10.1002/hep.24341 · DOI · Paper page
- Scott, 2008, Beta2-integrin-induced p38 MAPK activation is a key mediator in the CD14/TLR4/MD2-dependent uptake of lipopolysaccharide by hepatocytes, J Biol Chem, 283, 29433, 10.1074/jbc.M803905200 · DOI
- Liu, 2002, Role of toll-like receptors in changes in gene expression and NF-kappa B activation in mouse hepatocytes stimulated with lipopolysaccharide, Infect Immun, 70, 3433, 10.1128/IAI.70.7.3433-3442.2002 · DOI · Paper page
- Ishiguro, 2001, Syndecan-4 deficiency leads to high mortality of lipopolysaccharide-injected mice, J Biol Chem, 276, 47483, 10.1074/jbc.M106268200 · DOI
- Reis, 2011, LPS-induced formation of immunoproteasomes: TNF-alpha and nitric oxide production are regulated by altered composition of proteasome-active sites, Cell Biochem Biophys, 60, 77, 10.1007/s12013-011-9182-8 · DOI
- Stohwasser, 2000, Biochemical analysis of proteasomes from mouse microglia: induction of immunoproteasomes by interferon-gamma and lipopolysaccharide, Glia, 29, 355, 10.1002/(SICI)1098-1136(20000215)29:4<355::AID-GLIA6>3.0.CO;2-4 · DOI
- Angeles, 2012, Immune and non-immune functions of the immunoproteasome, Front Biosci, 17, 1904, 10.2741/4027 · DOI
- Coen, 2007, The mechanism of galactosamine toxicity revisited; a metabonomic study, J Proteome Res, 6, 2711, 10.1021/pr070164f · DOI
- Chen, 2004, Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A, FASEB J, 18, 914, 10.1096/fj.03-1204fje · DOI
- Brodsky, 2008, Dynamics of circulating microparticles in liver transplant patients, J Gastrointestin Liver Dis, 17, 261
- Butler, 2008, The antigen for Hep Par 1 antibody is the urea cycle enzyme carbamoyl phosphate synthetase 1, Lab Invest, 88, 78, 10.1038/labinvest.3700699 · DOI
- Potter, 2006, Carboxylesterases — detoxifying enzymes and targets for drug therapy, Curr Med Chem, 13, 1045, 10.2174/092986706776360969 · DOI
- Satoh, 1998, The mammalian carboxylesterases: from molecules to functions, Annu Rev Pharmacol Toxicol, 38, 257, 10.1146/annurev.pharmtox.38.1.257 · DOI
- Redinbo, 2005, Mammalian carboxylesterases: from drug targets to protein therapeutics, Drug Discov Today, 10, 313, 10.1016/S1359-6446(05)03383-0 · DOI
- Hatfield, 2011, Carboxylesterase inhibitors, Expert Opin Ther Pat, 21, 1159, 10.1517/13543776.2011.586339 · DOI
- Hatfield, 2010, Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin, Br J Pharmacol, 160, 1916, 10.1111/j.1476-5381.2010.00700.x · DOI
- Pindel, 1997, Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin, J Biol Chem, 272, 14769, 10.1074/jbc.272.23.14769 · DOI
- Humerickhouse, 2000, Characterization of CPT-11 hydrolysis by human liver carboxylesterase isoforms hCE-1 and hCE-2, Cancer Res, 60, 1189
- Quinney, 2005, Hydrolysis of capecitabine to 5′-deoxy-5-fluorocytidine by human carboxylesterases and inhibition by loperamide, J Pharmacol Exp Ther, 313, 1011, 10.1124/jpet.104.081265 · DOI
- Crow, 2007, Hydrolysis of pyrethroids by human and rat tissues: examination of intestinal, liver and serum carboxylesterases, Toxicol Appl Pharmacol, 221, 1, 10.1016/j.taap.2007.03.002 · DOI
- Shi, 2006, Anti-influenza prodrug oseltamivir is activated by carboxylesterase human carboxylesterase 1, and the activation is inhibited by antiplatelet agent clopidogrel, J Pharmacol Exp Ther, 319, 1477, 10.1124/jpet.106.111807 · DOI
- Sun, 2004, Methylphenidate is stereoselectively hydrolyzed by human carboxylesterase CES1A1, J Pharmacol Exp Ther, 310, 469, 10.1124/jpet.104.067116 · DOI
- Tang, 2006, Antiplatelet agents aspirin and clopidogrel are hydrolyzed by distinct carboxylesterases, and clopidogrel is transesterificated in the presence of ethyl alcohol, J Pharmacol Exp Ther, 319, 1467, 10.1124/jpet.106.110577 · DOI
- Zhang, 1999, Binding and hydrolysis of meperidine by human liver carboxylesterase hCE-1, J Pharmacol Exp Ther, 290, 314, 10.1016/S0022-3565(24)34901-8 · DOI
- Huang, 1993, Effect of hepatotoxic doses of paracetamol and carbon tetrachloride on the serum and hepatic carboxylesterase activity in mice, J Pharm Pharmacol, 45, 458, 10.1111/j.2042-7158.1993.tb05576.x · DOI
Cited by
Sorted by citations
Extracellular Vesicles in Liver Pathobiology: Small Particles With Big Impact
Hirsova, P., Ibrahim, S. H., Verma, V. K., Morton, L. A., Shah, V. H., LaRusso, N. F., Gores, G. J., & Malhi, H. (2016) · Hepatology · doi:10.1002/hep.28814 · Cited by 229
Andújar-Vera, F., Alés-Palmer, M. L., Muñoz-de-Rueda, P., Iglesias-Baena, I., & Ocete-Hita, E. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713562 · Cited by 10
Metadata
- Authors
- Rodríguez-Suárez, E., Gonzalez, E., Hughes, C., Conde-Vancells, J., Rudella, A., Royo, F., Palomo, L., Elortza, F., Lu, S. C., Mato, J. M., Vissers, J. P. C., & Falcón-Pérez, J. M.
- Venue
- Journal of Proteomics
- Publisher
- Elsevier BV
- Published
- 2014-05
- Volume
- 103
- Pages
- 227-240
- ISSN
- 1874-3919
- PMC
- PMC5119459
- Cited by
- 76
- References
- 3
- Language
- en
- Funders
- Fondo de Investigaciones Sanitarias (Institute of Health Carlos III (06/0621, PS09/00526, PI12/01064)
- Spanish Ministry (J.M.F.PRYC-2007-00228)
- National Institute of Health (R01 AT004896)
- Centro de Investigación Biomédica en Red en el Área temática de Enfermedades Hepáticas y Digestivas (CIBERehd)
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