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Prevalence and incidence of postpartum depression among healthy mothers: A systematic review and meta-analysis
Abstract
This review aims to examine the prevalence and incidence of postpartum depression among healthy mothers without prior history of depression including postpartum depression and who gave birth to healthy full-term infants. A systematic search of ClinicalTrials.gov, CINAHL, EMBASE, PsycINFO, and PubMed was performed for English articles from the inception of the database to November 2017, as well as a manual search of the reference lists of the included articles, and an expert panel was consulted. Across 15,895 articles, 58 articles (N = 37,294 women) were included in the review. The incidence of postpartum depression was 12% [95% CI 0.04-0.20] while the overall prevalence of depression was 17% [95% CI 0.15-0.20] among healthy mothers without a prior history of depression. Prevalence was similar regardless of the type of diagnostic tool used; however, there were statistical differences in the prevalence between different geographical regions, with the Middle-East having the highest prevalence (26%, 95% CI 0.13-0.39) and Europe having the lowest (8%, 95% CI 0.05-0.11). There was no statistical difference in prevalence between different screening time points, but an increasing prevalence was observed beyond six months postpartum. Intervention studies often neglect healthy mothers. This review reports a similar prevalence rate of postpartum depression among mothers without history of depression when compared to mothers with history of depression. Thus, future studies should place equal emphasis on this neglected group of mothers so that targeted interventions and follow-ups can be introduced at appropriate time points.
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“The incidence was 12% [95% CI 0.04–0.20] and the overall prevalence was 17% [95% CI 0.15–0.20] [5].”
From Mental health-related telemedicine interventions for pregnant women and new mothers: a systematic literature review (2023) · cites this paper as [5]
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“Regarding the postpartum period, depression has a worldwide prevalence of 10%–15%, whereas postpartum anxiety is somewhat more prevalent (Shorey et al., 2018).”
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The Use of Hypnosis during the Perinatal Period: A Systematic Review
Dumont, É., Ogez, D., Nahas, S., & El‐Baalbaki, G. (2023) · International Journal of Clinical and Experimental Hypnosis · doi:10.1080/00207144.2022.2160258 · Cited by 1
“This has important implications given that psychological difficulties associated with the perinatal period are now well documented (e.g., Dunkel Schetter, 2011; Schetter & Tanner, 2012; Shorey et al., 2018).”
BackgroundNursing discharge teaching of hospitalized postpartum women in China: A cross-sectional study
Li, S., Liu, Y., & Liu, G. (2023) · Gynecology and Obstetrics Clinical Medicine · doi:10.1016/j.gocm.2023.11.001 · Cited by 1
Explaining Crime Events and Criminal Careers
Wikström, P. H., Treiber, K., & Roman, G. D. (2024) · Oxford University Press eBooks · doi:10.1093/oso/9780198865865.003.0002 · Cited by 1
Ahmad, M. A., Awar, S. A. A. R. A., Sallam, G. S., Alkaabi, M. S. N., Smetanina, D., Statsenko, Y. A., & Zaręba, K. T. (2024) · Healthcare · doi:10.3390/healthcare12060650 · Cited by 5
Tai, C., Chen, L., Pan, W., Chiu, M.-J., Hsin, Y., & Lin, Y. (2024) · Advances in Cognitive Psychology · doi:10.5709/acp-0413-6 · Cited by 2
Bornstein, M. H., Manian, N., & Henry, L. M. (2024) · Infant Mental Health Journal · doi:10.1002/imhj.22110 · Cited by 1
Wu, C., Chou, L., Cheng, C., & Tu, M. J. (2024) · Family Relations · doi:10.1111/fare.13035 · Cited by 2
Hatakeyama, T., Matsumura, K., Tsuchida, A., & Inadera, H. (2024) · Neuropsychiatric Disease and Treatment · doi:10.2147/ndt.s456295 · Cited by 2
Murri, M. B., Garza, C. K., Grassi, L. G., & Muskin, P. R. (2024) · Springer eBooks · doi:10.1007/978-3-030-51366-5_113 · Cited by 1
Fatores associados à depressão pós-parto: uma análise de agregação
Netto, L. R., Mousinho, P. S. S., da Matta, J. S., Batista, T. G., Zago, A. M., Bubach, S., dos Santos, A. S., & Poton, W. L. (2024) · Medicina (Ribeirão Preto) · doi:10.11606/issn.2176-7262.rmrp.2024.213791 · Cited by 1
Doğum sonrası dönemde algılanan çok boyutlu sosyal desteğin kadınların depresyon düzeyine etkisi
Toptaner, N. E., Aykol, A. S., Yılmaz, A., & Dişsiz, M. (2024) · Sağlık akademisyenleri dergisi/Sağlık akademisyenler dergisi · doi:10.52880/sagakaderg.1552409 · Cited by 1
Ilska, M., Kołodziej‐Zaleska, A., & Brandt‐Salmeri, A. (2025) · Midwifery · doi:10.1016/j.midw.2025.104320 · Cited by 3
Dol, J., Campbell-Yeo, M. L., Aston, M. L., McMillan, D., & Grant, A. K. (2025) · JMIR Pediatrics and Parenting · doi:10.2196/62841 · Cited by 1
Effectiveness and treatment moderators of parenting interventions in Finnish perinatal primary care
Flykt, M. S., Kilpeläinen, M., Kinnunen, S., Salonen, M., Peltonen, K., Isosävi, S., & Lindblom, J. (2025) · Infant Mental Health Journal · doi:10.1002/imhj.70007 · Cited by 3
“Perinatal mental health problems are common, with pre-and postnatal depression and anxiety affecting about 10%–15% of new parents (Dennis et al., 2017; Shorey et al., 2018).”
Findley, H., McMahon, G., & Giallo, R. (2025) · Child & Family Social Work · doi:10.1111/cfs.13283 · Cited by 2
Motherhood Biographies and Health Over the Life Course
Thomeer, M. B., Ferguson, D., Crutchfield, C., & Reczek, C. (2025) · Sociology Compass · doi:10.1111/soc4.70036 · Cited by 2
Nagai, Y., & Nomura, K. (2025) · Annals of Medicine · doi:10.1080/07853890.2024.2445188 · Cited by 1
The biopsychosocial materno-semiotics framework: A holistic analytical tool for film studies
Priyadharshini, J., & Karthiga, R. K. J. (2025) · MethodsX · doi:10.1016/j.mex.2025.103279 · Cited by 5
“Furthermore, Shorey et al. [ 11 ] showed that social support networks and psychological well-being-focused interventions are more successful than pharmaceutical treatments alone at lowering postpartum depression symptoms.”
Halliday, B., Chatfield, S., Cameron, L., Hosking, J., Chynoweth, J., Stockley, L., Bailey, M. P., Shawe, J., Hawton, A., Hayward, C. J., et al. (2025) · Pilot and Feasibility Studies · doi:10.1186/s40814-025-01638-0 · Cited by 1
Resilience of pregnant Polish women during the war between Ukraine and Russia
Błaszczyk, Z., Wyrzychowski, A., Plewka, M. K., Nowakowska‐Domagała, K., Strzelecki, D., & Gawlik-Kotelnicka, O. (2025) · Scientific Reports · doi:10.1038/s41598-025-01108-w · Cited by 1
“The reduced availability of medical consultations, combined with unsettling media reports, contributed to heightened anxiety and uncertainty among expectant mothers 53,54 .”
Shiraishi, M., Kurashima, Y., Harada, R., & Ito, H. (2025) · Women & Health · doi:10.1080/03630242.2025.2509624 · Cited by 1
“In Japan, the prevalence of depression during pregnancy and at 1 month postpartum has been reported to be 11–15 percent (Tokumitsu et al. 2020), which is comparable to the global prevalence (Shorey et al. 2018; Yin et al. 2021).”
Morales, M. F., Narea, M., & Soto‐Ramírez, P. (2025) · Clinical Psychological Science · doi:10.1177/21677026251339435 · Cited by 1
“This observation holds even though the sample prevalence rates of depression in our study are higher compared with reports from other countries (Howard & Khalifeh, 2020; Shorey et al., 2018; Woody et al., ).”
Douleurs pelvipérinéales chroniques du post-partum : le point de vue de l’algologue
Freydier, M., Baude, C., Duraffourg, M., Plantevin, F., Dziadzko, M. A., & Barmaki, M. (2025) · Douleurs Évaluation - Diagnostic - Traitement · doi:10.1016/j.douler.2025.06.003 · Cited by 1
Sultan, T., Naveed, A., Ahmad, I., Kiani, M. M. L., Hassan, M. A., Bukhari, S. J. A., Naveed, M., & Naveed, A. (2025) · Pakistan BioMedical Journal · doi:10.54393/pbmj.v8i7.1255 · Cited by 1
Khoury, J. E., Jambon, M. M., Pattison, M., González, A., & Atkinson, L. R. (2025) · Child Maltreatment · doi:10.1177/10775595251370683 · Cited by 1
“Approximately 10% to 20% of women around the world experience anxiety or depression during the period spanning pregnancy to the fi rst year postpartum (Dennis et al., 2017; Shorey et al., 2018).”
Sociodemographic predictors of postpartum post-traumatic stress symptoms—cross-sectional study
Burdecka, J., & Szablewska, A. W. (2025) · Frontiers in Psychology · doi:10.3389/fpsyg.2025.1681808 · Cited by 1
Cuthbert, G., Likindikoki, S. L., Kakoko, D., & Abeid, M. S. (2025) · PLOS mental health. · doi:10.1371/journal.pmen.0000315 · Cited by 1
“…by an increased psychosocial demand during the preparation for and transitioning to motherhood and overwhelming nature of the responsibility and expectations associated with such role in the absence of an adequate support system which tend to exacerbate feelings of isolation and inadequacy [28].”
Uçar, T., YILDIRIM, A. D., Yılmaz, S. D., Kaya, G. D., & Koçak, Y. Ç. (2025) · Journal of Immigrant and Minority Health · doi:10.1007/s10903-025-01796-6 · Cited by 1
Rajendran, V. R., & Mangayarkarasi, K. M. D. K. (2025) · International Journal of Reproduction Contraception Obstetrics and Gynecology · doi:10.18203/2320-1770.ijrcog20253545 · Cited by 1
Rowe, H. J., Fisher, J., Meggetto, E., Lees, H., & Makleff, S. (2025) · BMC Health Services Research · doi:10.1186/s12913-025-13629-1 · Cited by 1
“…mental disorders’ vary, but recent reviews report 17% (95% CI: 12, 21) prevalence of postnatal depressive disorder assessed from clinical interviews among healthy women without a history of depression [5], and 9.9% (95%CI: 6.1, 13.1) for any post-natal anxiety disorder at 1–24 weeks postpartum [6].”
InfluentialForeman, I., Hunt, T., Peterkin, J., & Hodgekins, J. (2025) · Community Mental Health Journal · doi:10.1007/s10597-025-01543-z · Cited by 1
“Research typically focuses on perinatal depression and anxiety, given these are commonly experienced (Shorey et al., 2018 ; Viswasam et al., 2019 ).”
Interplay of traumatic birth experiences and postnatal depression in Pakistani women
Batool, S. S., Chatrath, S. K., Batool, S. A., Batool, R., Ayers, S., & Webb, R. (2025) · Scientific Reports · doi:10.1038/s41598-025-27209-0 · Cited by 1
Jamet, C., & Tebeka, S. (2025) · médecine/sciences · doi:10.1051/medsci/2025238 · Cited by 1
Mandated perinatal mental health screening in California: a mixed-methods exploration
Woofter, R. C., James, K. F., Rao, R., Richards, M., Choi, K. R., & Sudhinaraset, M. (2026) · Health Affairs Scholar · doi:10.1093/haschl/qxag021 · Cited by 1
Metadata
- Authors
- Shorey, S., Chee, C. Y. I., Ng, E. D., Chan, Y. H., Tam, W. W. S., & Chong, Y. S.
- Affiliations
- National University of Singapore (SG)
- National University Hospital (SG)
- Corresponding author
- Shorey, Shefaly
- ORCID
- Venue
- Journal of Psychiatric Research
- Publisher
- Elsevier BV
- Published
- 2018-09
- Volume
- 104
- Pages
- 235-248
- ISSN
- 0022-3956 (ISSN-L)
- OpenAlex
- W2885511794
- Cited by
- 1,055
- References
- 106
- Citations by year
- 2026: 127 · 2025: 160 · 2024: 181 · 2023: 175 · 2022: 166 · 2021: 136 · 2020: 76 · 2019: 28 · 2018: 4
- FWCI
- 11.06
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Psychiatric Research (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Maternal Mental Health During Pregnancy and Postpartum
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and Neonatal Healthcare
- Health Sciences › Medicine › Obstetrics and Gynecology › Maternal and Perinatal Health Interventions
- Keywords
- postpartum depression, prevalence, incidence, term infants, postpartum screening, diagnostic tools, regional variation, postpartum period
- MeSH terms
- Female, Humans, Mothers, Incidence, Prevalence, Databases, Factual, Depression, Postpartum
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