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The landscape of cognitive function in recovered COVID-19 patients
Open accessAbstract
This study aims to evaluate the impacts of COVID-19 on cognitive functions in recovered patients and its relationship with inflammatory profiles. Twenty-nine patients recovered from COVID-19 as confirmed by negative nucleic tests for two consecutive times were recruited. A total of 29 age-, gender- and education-matched healthy controls were also recruited. The cognitive functions of all subjects were evaluated by the iPad-based online neuropsychological tests, including the Trail Making Test (TMT), Sign Coding Test (SCT), Continuous Performance Test (CPT), and Digital Span Test (DST). Blood samples from all patients were collected for examining inflammatory profiles, including interleukin-2 (IL-2), IL-4, IL-6, IL-10, tumor necrosis factor-α (TNF-α), interferon-γ (IFN-γ), and C-reactive protein (CRP). The relationship between cognitive functions and inflammatory profiles were analyzed by Pearson correlation. In results, although no significant differences were found in TMT, SCT, and DST between the two groups, patients with COVID-19 scored lower in the correct number of the second and third parts of CPT, they also scored higher in the missing number of the third part of CPT (all P < 0.05). In patients with COVID-19, there was a trend of significant difference for lower reaction time in the first and second parts of CPT (P = 0.050, and 0.051, respectively), as well as the lower correct number of the second part of CPT (P = 0.050). Correlation analysis showed that the reaction time for the first and second parts of CPT was positively correlated with the CRP levels (r = 0.557 and 0.410, P < 0.05). In conclusion, our findings indicated that cognitive impairments exist even in patients recovered from COVID-19, and might be possibly linked to the underlying inflammatory processes.
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“Preliminary studies of convalescent COVID-19 patients using comprehensive neuropsychological assessment showed cognitive impairment two to four weeks after infection.”
From Cognitive decline following acute viral infections: literature review and projections for post-COVID-19 (2022) · cites this paper as [140]
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“Attentional deficits were the most relevant changes [140, 141].”
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Cites
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China
Huang, C., Wang, Y., Li, X., Ren, L., Zhao, J., Hu, Y., Zhang, L., Fan, G., Xu, J., Gu, X., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30183-5 · Cited by 48,884
Chen, N., Zhou, M., Dong, X., Qu, J., Gong, F., Han, Y., Qiu, Y., Wang, J., Liu, Y., Wei, Y., et al. (2020) · The Lancet · doi:10.1016/s0140-6736(20)30211-7 · Cited by 21,415
Wang, D., Hu, B., Hu, C., Zhu, F., Liu, X., Zhang, J., Wang, B., Xiang, H., Cheng, Z., Xiong, Y., et al. (2020) · JAMA · doi:10.1001/jama.2020.1585 · Cited by 20,148
Self-citationLa certeza de lo impredecible: Cultura Educación y Sociedad en tiempos de COVID19
Martínez González, M. (2020) · DSPACE System - Metalibrary (University of the Coast) · Cited by 18,463
Lai, C.-C., Shih, T.-P., Ko, W.-C., Tang, H.-J., & Hsueh, P.-R. (2020) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2020.105924 · Cited by 6,068
Clinical characteristics of 140 patients infected with SARS‐CoV‐2 in Wuhan, China
Zhang, J., Dong, X., Cao, Y., Yuan, Y.-D., Yang, Y., Yan, Y., Akdiş, C. A., & Gao, Y. (2020) · Allergy · doi:10.1111/all.14238 · Cited by 4,088
Peiris, J., Chu, C., Cheng, V., Chan, K., Hung, I., Poon, L., Law, K., Tang, B., Hon, T., Chan, C., et al. (2003) · The Lancet · doi:10.1016/s0140-6736(03)13412-5 · Cited by 2,375
Chang, D., Lin, M., Wei, L., Xie, L., Zhu, G., Cruz, C. S. D., & Sharma, L. (2020) · JAMA · doi:10.1001/jama.2020.1623 · Cited by 709
Liu, Z., Xiao, X., Wei, X., Li, J., Yang, J., Tan, H., Zhu, J., Zhang, Q., Wu, J., & Liu, L. (2020) · Journal of Medical Virology · doi:10.1002/jmv.25726 · Cited by 697
COVID-19 Disease due to SARS-CoV-2 (Novel Coronavirus)
Carlos, W. G., Cruz, C. S. D., Cao, B., Pasnick, S., & Jamil, S. M. (2020) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.2014p7 · Cited by 583
Cited by
Sorted by citations
Items 401–438 of 438
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Anbazhagan, R., Rajendran, K. P., Kalyanaraman, M., Karthik, R., Ramanidhi, S., Sridhar, S. B., Shareef, J., Thomas, S., & Janakiraman, A. K. (2024) · Springer eBooks · doi:10.1007/978-981-99-7557-0_38
Matiash, M. M., & Galanta, Y. A. (2025) · INTERNATIONAL NEUROLOGICAL JOURNAL · doi:10.22141/2224-0713.20.8.2024.1130 · Cited by 1
de Lazcano, A. R., Pérez-Núñez, P., Pallarès‐Sastre, M., García-Sanchoyerto, M., García, I., & Amayra, I. (2025) · Clinical Autonomic Research · doi:10.1007/s10286-025-01106-y · Cited by 1
Lotfi, A., Rajaei, A. R., & Nayyeri, M. (2025) · Journal of Psychological Science · doi:10.61186/jps.23.144.13
Chen, T., Shen, Z.-H., Tsai, M., Weng, C., & Leong, M. K. (2025) · Tzu Chi Medical Journal · doi:10.4103/tcmj.tcmj_226_24
Hasan, S. Y., & Yasir, S. J. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5221429
Nikishkova, I. (2023) · Ukrains kyi Visnyk Psykhonevrolohii · doi:10.36927/2079-0325-v31-is2-2023-14
Rodríguez-Rodríguez, M., Rodríguez‐Agudelo, Y., Soto-Moreno, F. J., García-Santos, A., Lopez-Gonzalez, D. B., González-Navarro, M., Paz-Rodríguez, F., Chávez-Oliveros, M., Lozano-Tovar, S., González-Alonso, K., et al. (2025) · Neurología (English Edition) · doi:10.1016/j.nrleng.2025.05.002
COVID iraunkorraren sindromearen profil neuropsikologikoa: berrikuspen sistematikoa
Larranaga, I., & Sistiaga, A. (2025) · Uztaro: giza eta gizarte-zientzien aldizkaria · doi:10.26876/uztaro5109
Yoo, H. (2025) · JMIR Human Factors · doi:10.2196/71303
Yeh, A.-Y., Chao, Y., Strauss, S. M., & Chou, C. (2025) · Western Journal of Nursing Research · doi:10.1177/01939459251350812
Toalombo, M. G. G., Pazmiño, A. C. T., Parra, A. C. V., & Torres, A. (2025) · Revista Ciencia Innovadora · doi:10.64422/rci.v3n1.2025.1
Impacts of COVID-19 on cognitive functioning of older adults: a longitudinal study
Rodríguez-Díaz, M., & Mendoza-Ruvalcaba, N. (2025) · Journal of Global Ageing · doi:10.1332/29767202y2025d000000034
Prevalence of post-COVID syndrome among COVID-19 survivors in Iraqi society
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Neuroprotection in outpatient treatment of post-covid syndrome
Ivanova, M. I., Иванов, В. М., Коваленко, А. Л., Petrov, A. Y., & Таликова, Е. В. (2025) · Russian neurological Journal · doi:10.30629/2658-7947-2025-30-3-53-60
Dotor-Llerena, A. L., Reyes-Long, S., Najera-García, L., Hernández‐Corral, S., Aréchaga-Ocampo, E., Avendaño-Ortiz, K., Trejo‐Martínez, D., Rosell-Becerril, H., Cortes-Altamirano, J. L., & Alfaro-Rodríguez, A. (2025) · Biomedicines · doi:10.3390/biomedicines13092267
Kmita, L. C., Corleto, L. V., Tiba, M. N., Ruggieri, K. R., Moser, A. D. D. L., & Bernardelli, R. S. (2025) · Cogitare Enfermagem · doi:10.1590/ce.v30i0.96346es
Kmita, L. C., Corleto, L. V., Tiba, M. N., Ruggieri, K. R., Moser, A. D. D. L., & Bernardelli, R. S. (2025) · Cogitare Enfermagem · doi:10.1590/ce.v30i0.96346en
Kmita, L. C., Corleto, L. V., Tiba, M. N., Ruggieri, K. R., Moser, A. D. D. L., & Bernardelli, R. S. (2025) · Cogitare Enfermagem · doi:10.1590/ce.v30i0.96346pt
Blackmon, K., Day, G. S., Powers, H. R., Bosch, W., Prabhakaran, D., Woolston, D. J., & Pedraza, O. (2022) · Figshare · doi:10.6084/m9.figshare.20408581
Blackmon, K., Day, G. S., Powers, H. R., Bosch, W., Prabhakaran, D., Woolston, D. J., & Pedraza, O. (2022) · Figshare · doi:10.6084/m9.figshare.20408584
Ollila, H., Pihlaja, R., Koskinen, S. K., Tuulio‐Henriksson, A., Salmela, V. R., Tiainen, M., Hokkanen, L., & Hästbacka, J. (2022) · Figshare · doi:10.6084/m9.figshare.20347613
Zhou, Y., Xu, J., Hou, Y., Leverenz, J. B., Kallianpur, A. R., Mehra, R., Liu, Y., Yu, H., Pieper, A. A., Jehi, L., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14759706
Zhou, Y., Xu, J., Hou, Y., Leverenz, J. B., Kallianpur, A. R., Mehra, R., Liu, Y., Yu, H., Pieper, A. A., Jehi, L., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14759694
Blackmon, K., Day, G. S., Powers, H. R., Bosch, W., Prabhakaran, D., Woolston, D. J., & Pedraza, O. (2022) · Figshare · doi:10.6084/m9.figshare.20408578
Long-Term Health Consequences of SARS-CoV-2: Reaction Time and Brain Fog
Lesac, A., Popović, B., Zavidić, T., Todorović, N., Petrović, V., Pilipović-Broćeta, N., Miljković, A. R., Ljubotina, A., & Dejhalla, E. (2025) · Neurology International · doi:10.3390/neurolint18010006
General Effects of the COVID-19 Pandemic on Cognition
Podlešek, A., & Kavcic, V. (2025) · Springer eBooks · doi:10.1007/978-3-032-03895-1_2 · Cited by 1
Kutkova, A. (2026) · Bulletin of psychotherapy · doi:10.25016/2782-652x-2025-0-96-58-68
Malete, L., Ezeamama, A. E., Ricketts, C., Joachim, D., Naghibolhosseini, M., Zayernouri, M., Ocansey, R. T.-A., Muomah, R. C., Tladi, D., & Ndabi, J. S. (2026) · medRxiv · doi:10.64898/2026.02.16.26346431
Dynamic multivariate patterns of brain structure–neuropsychiatric symptom associations in long COVID
Bao, W., Ye, G., Wang, T. T., Quan, X., Zhu, Q., Fan, L., Li, H., Zeng, W., Mu, J. J., Zhu, R., et al. (2026) · Brain Communications · doi:10.1093/braincomms/fcag232
Seagly, K., Sohlberg, M. M., Dunn, R., Waldron-Perrine, B., Mashima, P. A., Rothbart, A., & Paul, D. (2026) · Perspectives of the ASHA Special Interest Groups · doi:10.1044/2026_persp-25-00297
The Impact of Long COVID on Cognitive Functioning
Siedlecki, K. L., & Kobrinsky, V. (2026) · Journal of Intelligence · doi:10.3390/jintelligence14080157
Duca, G. D., Camici, M., Sperduti, I., Brita, A. C., Maresca, M., Pinnetti, C., Mastrorosa, I., Mazzotta, V., & Antinori, A. (2026) · Neurology International · doi:10.3390/neurolint18090163
Luo, X., Zeng, S., Liu, S., Li, Y., Fang, L., Li, D., Xin, Q., Du, S., Xu, Y., & Zhang, B. (2026) · Journal of Zhejiang University SCIENCE B · doi:10.1631/jzus.b2500553 · Cited by 1
A Covid19-fertőzés repülésbiztonsági aspektusai 1. rész
Guth-Orji, Á. J. (2023) · Haditechnika · doi:10.23713/ht.57.2.05
Metadata
- Authors
- Zhou, H., Lu, S., Chen, J., Wei, N., Wang, D., Lyu, H., Shi, C., & Hu, S.
- Affiliations
- First Affiliated Hospital Zhejiang University (CN)
- Peking University (CN)
- Corresponding author
- Shi, Chuan
- Hu, Shaohua
- Venue
- Journal of Psychiatric Research
- Publisher
- Elsevier BV
- Published
- 2020-10
- Volume
- 129
- Pages
- 98-102
- ISSN
- 0022-3956 (ISSN-L)
- PMC
- PMC7324344
- OpenAlex
- W3040367645
- Cited by
- 440
- References
- 35
- Citations by year
- 2026: 10 · 2025: 37 · 2024: 55 · 2023: 82 · 2022: 137 · 2021: 109 · 2020: 8
- FWCI
- 36.35
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Journal of Psychiatric Research (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Sci-Tech Academy, Zhejiang University
- Topics
- Health Sciences › Medicine › Clinical Neurology › Long-Term Effects of COVID-19
- Health Sciences › Medicine › Infectious Diseases › COVID-19 Clinical Research Studies
- Social Sciences › Psychology › Clinical Psychology › COVID-19 and Mental Health
- Keywords
- COVID-19 pandemic, post-COVID cognitive impairment, recovered patients, inflammatory markers, C-reactive protein, continuous performance test, reaction time, neuropsychological assessment, interleukins, TNF-α, interferon-gamma
- MeSH terms
- Betacoronavirus, COVID-19, SARS-CoV-2, Adult, Female, Humans, Inflammation, Male, Middle Aged, Neuropsychological Tests, Pneumonia, Viral, Survivors, Coronavirus Infections, Pandemics, Cognitive Dysfunction
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