Cited by 1,473Anxiety, Depression, Psychometrics, Treatment, Cognitive ProcessesMental Health Treatment and AccessPsychometric Methodologies and Testing

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Detecting and monitoring depression with a two-item questionnaire (PHQ-2)

Löwe, Bernd, Kroenke, Kurt, Gräfe, Kerstin·2005·Journal of Psychosomatic Research

DOI 10.1016/j.jpsychores.2004.09.006

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Abstract

Objective This study evaluates the two-item Patient Health Questionnaire (PHQ-2) as a measure for diagnosing and monitoring depression.Methods We assessed construct validity in a cross-sectional sample of 1619 medical outpatients (mean age 43+/-14 years, 64% female) by comparing the PHQ-2 to four longer self-report questionnaires. Criterion validity was established in a subsample of 520 participants with reference to the Structured Clinical Interview for DSM-IV (SCID). Sensitivity to change was investigated in a prospective study of 167 patients who completed the SCID both at baseline and the 1-year follow-up.Results With reference to the SCID, the PHQ-2 had a sensitivity of 87% and a specificity of 78% for major depressive disorder and a sensitivity of 79% and a specificity of 86% for any depressive disorder. Its diagnostic performance was comparable with that of longer depression scales. PHQ-2 change scores accurately reflected improved, unchanged, and deteriorated depression outcomes.Conclusion The PHQ-2 performed favorably with respect to a standard diagnostic interview, as well as established depression scales and proved sensitive to change. Thus, the PHQ-2 appears promising as a brief multipurpose measure for detecting depression, grading its severity, and monitoring outcomes over time.

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The Measurement of Observer Agreement for Categorical Data
Landis, J. R., & Koch, G. G. (1977) · Biometrics · doi:10.2307/2529310 · Cited by 81,148
The Hospital Anxiety and Depression Scale
Zigmond, A. S., & Snaith, R. P. (1983) · Acta Psychiatrica Scandinavica · doi:10.1111/j.1600-0447.1983.tb09716.x · Cited by 47,139
The PHQ-9: Validity of a brief depression severity measure
Kroenke, K., Spitzer, R. L., & Williams, J. B. W. (2001) · Journal of General Internal Medicine · doi:10.1046/j.1525-1497.2001.016009606.x · Cited by 44,910
Self-citation
Untitled work
(1992) · PubMed · Cited by 33,716
The MOS 36-ltem Short-Form Health Survey (SF-36): I. Conceptual Framework and Item Selection
Ware, J. E., & Sherbourne, C. D. (1992) · Medical Care · doi:10.1097/00005650-199206000-00002 · Cited by 30,033
A 12-Item Short-Form Health Survey: Construction of Scales and Preliminary Tests of Reliability and Validity
WARE, J. E., KOSINSKI, M., & KELLER, S. D. (1996) · Medical Care · doi:10.1097/00005650-199603000-00003 · Cited by 17,392
Validation and Utility of a Self-report Version of PRIME-MD<SUBTITLE>The PHQ Primary Care Study</SUBTITLE>
Spitzer, R. L. (1999) · JAMA · doi:10.1001/jama.282.18.1737 · Cited by 9,802
The validity of the Hospital Anxiety and Depression Scale
Bjelland, I., Dahl, A. A., Haug, T. T., & Neckelmann, D. (2002) · Journal of Psychosomatic Research · doi:10.1016/s0022-3999(01)00296-3 · Cited by 9,779
Measuring nominal scale agreement among many raters.
Fleiss, J. L. (1971) · Psychological Bulletin · doi:10.1037/h0031619 · Cited by 8,733
The Epidemiology of Major Depressive Disorder: Results From the National Comorbidity Survey Replication (NCS-R)
Kessler, R. C., Berglund, P., Demler, O., Jin, R., Koretz, D., Merikangas, K. R., Rush, A. J., Walters, E. E., & Wang, P. S. (2003) · JAMA · doi:10.1001/jama.289.23.3095 · Cited by 7,988

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Authors: Löwe, B., Kroenke, K., & Gräfe, K.
Affiliations: Regenstrief Institute (US)
Heidelberg University (DE)
Corresponding author: Löwe, Bernd
ORCID: Löwe, Bernd
Kroenke, Kurt
Venue: Journal of Psychosomatic Research
Publisher: Elsevier BV
Published: 2005-02
Volume: 58
Issue: 2
Pages: 163-171
ISSN: 0022-3999 (ISSN-L)
DOI: 10.1016/j.jpsychores.2004.09.006
OpenAlex: W2065455682
Semantic Scholar: cad15cd078a4536990557c27e4c244a613c19d84
Cited by: 1,473
References: 43
Citations by year: 2026: 96 · 2025: 132 · 2024: 138 · 2023: 150 · 2022: 150 · 2021: 175 · 2020: 107 · 2019: 84 · 2018: 69 · 2017: 51 · 2016: 51 · 2015: 50 · 2014: 49 · 2013: 31 · 2012: 31
FWCI: 14.65
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of Psychosomatic Research (publishedVersion)
PubMed (publishedVersion)
Funders: Pfizer
Max Kade Foundation
Topics: Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
Social Sciences › Decision Sciences › Management Science and Operations Research › Psychometric Methodologies and Testing
Keywords: PHQ-2, Patient Health Questionnaire, depression screening, depression diagnosis, depression monitoring, construct validity, criterion validity, sensitivity to change, major depressive disorder, depressive disorders, medical outpatients
MeSH terms: Adult, Cross-Sectional Studies, Depressive Disorder, Female, Follow-Up Studies, Humans, Male, Surveys and Questionnaires, Sensitivity and Specificity, Disease Progression

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Detecting and monitoring depression with a two-item questionnaire (PHQ-2)

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