Sleep in Schizophrenia
Abstract
Both subjective and objective assessments of sleep patterns in schizophrenia include a wide range of dyssomnias, with insomnia being the most frequently cited. Early and middle insomnia can range from mild disruption to total sleeplessness. Severe insomnia is a prodromal sign of clinical exacerbation or relapse. In general, most antipsychotic agents (APs) ameliorate this insomnia. However, in some schizophrenics APs can be associated with residual insomnia or with significant daytime somnolence. Furthermore, in some schizophrenics APs can induce or exacerbate comorbid sleep disorders such as restless legs syndrome, sleep-disordered breathing, and parasomnias such as sleepwalking.
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Circadian disruption is a common prodrome of schizophrenia.
“Indeed, circadian disruption is a common prodrome of SZ145, although the nature of the relationship remains unclear, in part because circadian disruption has been studied less extensively in SZ than other mood disorders.”
From Circadian rhythm disruption and mental health (2020) · cites this paper as [145]
The severity of schizophrenia symptoms has been associated with the extent of sleep or circadian rhythm disruption.
“Furthermore, the severity of SZ symptoms has been associated with the extent of sleep or circadian rhythm disruption143–145.”
From Circadian rhythm disruption and mental health (2020) · cites this paper as [145]
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Circadian rhythm disruption and mental health
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- Authors
- Benson, K. L.
- Affiliations
- Harvard University (US)
- Corresponding author
- Benson, Kathleen L.
- Venue
- Sleep Medicine Clinics
- Publisher
- Elsevier BV
- Published
- 2015-03
- Volume
- 10
- Issue
- 1
- Pages
- 49-55
- ISSN
- 1556-407X (ISSN-L)
- OpenAlex
- W2188201135
- Cited by
- 70
- References
- 39
- Citations by year
- 2026: 4 · 2025: 3 · 2024: 9 · 2023: 2 · 2022: 7 · 2021: 6 · 2020: 7 · 2019: 9 · 2018: 6 · 2017: 9 · 2016: 1 · 2015: 5 · 2013: 1
- FWCI
- 0.90
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Sleep Medicine Clinics (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
- Health Sciences › Medicine › Psychiatry and Mental health › Schizophrenia research and treatment
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Keywords
- schizophrenia, sleep disorders, insomnia, dyssomnia, antipsychotic adverse effects, daytime somnolence, restless legs syndrome, sleep-disordered breathing, parasomnias, sleepwalking, relapse
- MeSH terms
- Humans, Schizophrenia, Sleep Wake Disorders, Antipsychotic Agents
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