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Activation of ocular surface mast cells promotes corneal neovascularization
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“The underlying mechanisms have not been explored in detail, but it was reported that corneal mast cells produce vascular endothelial growth factor (VEGF) and neurturin, which, respectively, have angiogenic and neurotrophic actions. In agreement with this, inappropriately high levels of mast cell‐derived VEGF promote neovascularization in the adult cornea, that is, excessive angiogenesis that can”
From Mast cell ontogeny: From fetal development to life‐long health and disease (2023) · cites this paper as [118]
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Cites
IgE and mast cells in allergic disease
Galli, S. J., & Tsai, M. (2012) · Nature Medicine · doi:10.1038/nm.2755 · Cited by 1,799
Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis
Coussens, L. M., Raymond, W. W., Bergers, G., Laig-Webster, M., Behrendtsen, O., Werb, Z., Caughey, G. H., & Hanahan, D. (1999) · Genes & Development · doi:10.1101/gad.13.11.1382 · Cited by 946 · cited 1×
“However, the majority of the studies on mast cell-mediated angiogenesis have been limited to tumor biology [15, 16].”
Background
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Cited by
Sorted by citations
Mast cell ontogeny: From fetal development to life‐long health and disease
Chia, S. L., Kapoor, S., Carvalho, C., Bajénoff, M., & Gentek, R. (2023) · Immunological Reviews · doi:10.1111/imr.13191 · Cited by 60
Metadata
- Authors
- Cho, W., Mittal, S. K., Elbasiony, E., & Chauhan, S. K.
- Venue
- The Ocular Surface
- Publisher
- Elsevier BV
- Published
- 2020-10
- Volume
- 18
- Issue
- 4
- Pages
- 857-864
- ISSN
- 1542-0124
- PMC
- PMC7686271
- Cited by
- 35
- References
- 2
- Language
- en
- Funders
- National Eye Institute
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- Cho, W., Mittal, S. K., Elbasiony, E., & Chauhan, S. K. (2020). Activation of ocular surface mast cells promotes corneal neovascularization. The Ocular Surface. https://doi.org/10.1016/j.jtos.2020.09.002