Erectile dysfunction: AUA guideline

Burnett, Arthur L.; Nehra, Ajay; Breau, Rodney H.; Culkin, Daniel J.; Faraday, Martha M.; Hakim, Lawrence S.; Heidelbaugh, Joel; Khera, Mohit; McVary, Kevin T.; Miner, Martin M.; Nelson, Christian J.; Sadeghi-Nejad, Hossein; Seftel, Allen D.; Shindel, Alan W.

doi:10.1016/j.juro.2018.05.004

Cited by 949Sexual function and dysfunction studiesUrological Disorders and TreatmentsUrinary Bladder and Prostate Research

Erectile dysfunction: AUA guideline

Burnett, Arthur L., Nehra, Ajay, Breau, Rodney H., Culkin, Daniel J., Faraday, Martha M., Hakim, Lawrence S., Heidelbaugh, Joel, Khera, Mohit +6 more·2018·Journal of Urology

DOI 10.1016/j.juro.2018.05.004

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Abstract

PURPOSE: The purpose of this guideline is to provide a clinical strategy for the diagnosis and treatment of erectile dysfunction. MATERIALS AND METHODS: A systematic review of the literature using the Pubmed, Embase, and Cochrane databases (search dates 1/1/1965 to 7/29/17) was conducted to identify peer-reviewed publications relevant to the diagnosis and treatment of erectile dysfunction. Evidence-based statements were based on body of evidence strength Grade A, B, or C and were designated as Strong, Moderate, and Conditional Recommendations with additional statements presented in the form of Clinical Principles or Expert Opinions. RESULTS: The American Urological Association has developed an evidence-based guideline on the management of erectile dysfunction. This document is designed to be used in conjunction with the associated treatment algorithm. CONCLUSIONS: Using the shared decision-making process as a cornerstone for care, all patients should be informed of all treatment modalities that are not contraindicated, regardless of invasiveness or irreversibility, as potential first-line treatments. For each treatment, the clinician should ensure that the man and his partner have a full understanding of the benefits and risk/burdens associated with that choice.

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The majority of review papers and clinical guidelines on ED approach assessment and treatment from a purely medical perspective and pay little attention to psychosocial aspects.
“By now, there are several review papers and clinical guidelines available on ED,9, 10, 11, 12, 13 but the majority of these papers approach the assessment and treatment of ED from a purely medical perspective and pay only little attention to describing the psychosocial aspects of ED.”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [12]
Treatment of ED is not cause-specific.
“Hence, it can be stated that the treatment of ED is not cause-specific.12”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [12]
Shared decision-making predicts a better course, adherence, and outcome of therapy because patients have more realistic treatment expectations.
“Not only does shared decision-making increase patient autonomy, it also predicts a better course, adherence, and outcome of therapy because patients have more realistic treatment expectations.10, 11, 12”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [12]

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“Hence, it can be stated that the treatment of ED is not cause-specific.(12)”
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Systematic Review and Meta-Analysis of 16 Randomized Controlled Trials of Clinical Outcomes of Low-Intensity Extracorporeal Shock Wave Therapy in Treating Erectile Dysfunction
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Platelet-rich Plasma for the Treatment of Erectile Dysfunction: A Prospective, Randomized, Double-blind, Placebo-controlled Clinical Trial
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Hypertension and Erectile Dysfunction: Breaking Down the Challenges
de Oliveira, A. A., & Nunes, K. P. (2020) · American Journal of Hypertension · doi:10.1093/ajh/hpaa143 · Cited by 63 · see citing works
Health, Sexual Activity, and Sexual Satisfaction
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Princeton IV consensus guidelines: PDE5 inhibitors and cardiac health.
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Risk factors for erectile dysfunction in diabetes mellitus: a systematic review and meta-analysis
Dilixiati, D., Waili, A., Tuerxunmaimaiti, A., Tao, L., Zebibula, A., & Rexiati, M. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1368079 · Cited by 59 · see citing works
Photoacoustic image-guided corpus cavernosum intratunical injection of adipose stem cell-derived exosomes loaded polydopamine thermosensitive hydrogel for erectile dysfunction treatment
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Restorative Therapies for Erectile Dysfunction: Position Statement From the Sexual Medicine Society of North America (SMSNA)
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The broad reach and inaccuracy of men’s health information on social media: analysis of TikTok and Instagram
Dubin, J. M., Aguiar, J., Lin, J. S., Greenberg, D. R., Keeter, M. K., Fantus, R. J., Pham, M. N., Hudnall, M. T., Bennett, N., Brannigan, R. E., et al. (2022) · International Journal of Impotence Research · doi:10.1038/s41443-022-00645-6 · Cited by 59 · see citing works
HIV and Sexual Dysfunction in Men
Vincentis, S. D., Tartaro, G., Rochira, V., & Santi, D. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10051088 · Cited by 55 · see citing works
Cyclic GMP modulating drugs in cardiovascular diseases: mechanism-based network pharmacology
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The Effect of Phosphodiesterase-type 5 Inhibitors on Erectile Function: An Overview of Systematic Reviews
Pyrgidis, N., Mykoniatis, I., Haidich, A., Tirta, M., Talimtzi, P., Kalyvianakis, D., Ouranidis, A., & Hatzichristou, D. G. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.735708 · Cited by 52 · see citing works
Is Platelet Rich Plasma Safe and Effective in Treatment of Erectile Dysfunction? Randomized Controlled Study
Shaher, H., Fathi, A., Elbashir, S., Abdelbaki, S. A., & Soliman, T. T. (2023) · Urology · doi:10.1016/j.urology.2023.01.028 · Cited by 52 · see citing works
Comparison of Long-Term Results and Couples’ Satisfaction with Penile Implant Types and Brands: Lessons Learned From 883 Patients With Erectile Dysfunction Who Underwent Penile Prosthesis Implantation
Çayan, S., Aşçı, R., Efesoy, O., Bolat, M. S., Akbay, E., & Yaman, Ö. (2019) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2019.04.013 · Cited by 52 · see citing works
Sildenafil beyond erectile dysfunction and pulmonary arterial hypertension: Thinking about new indications
Ala, M., Jafari, R. M., & Dehpour, A. R. (2020) · Fundamental and Clinical Pharmacology · doi:10.1111/fcp.12633 · Cited by 52 · see citing works
Novel Treatments of Erectile Dysfunction: Review of the Current Literature
Raheem, O. A., Natale, C., Dick, B. P., Reddy, A. G., Yousif, A. A., Khera, M., & Baum, N. H. (2020) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2020.03.005 · Cited by 50 · see citing works
Cross‐sectional and comparative analysis of videos on erectile dysfunction treatment on YouTube and TikTok
Babar, M., Loloi, J., Patel, R. D., Singh, S. R., Azhar, U., Maria, P., Small, A., & Watts, K. L. (2022) · Andrologia · doi:10.1111/and.14392 · Cited by 49 · see citing works
Meta-analysis of randomized controlled trials that assess the efficacy of low-intensity shockwave therapy for the treatment of erectile dysfunction
Campbell, J. D., Trock, B. J., Oppenheim, A. R., Anusionwu, I., Gor, R. A., & Burnett, A. L. “. (2019) · Therapeutic Advances in Urology · doi:10.1177/1756287219838364 · Cited by 48 · see citing works
The good, bad, and the ugly of regenerative therapies for erectile dysfunction
Campbell, J. D., Milenković, U., Usta, M. F., Albersen, M., & Bivalacqua, T. J. (2020) · Translational Andrology and Urology · doi:10.21037/tau.2019.10.06 · Cited by 46 · see citing works
Is It All in My Head? Self-reported Psychogenic Erectile Dysfunction and Depression Are Common Among Young Men Seeking Advice on Social Media
Jiang, T., Osadchiy, V., Mills, J. N., & Eleswarapu, S. V. (2020) · Urology · doi:10.1016/j.urology.2020.04.100 · Cited by 46 · see citing works
Penile low intensity shock wave treatment for PDE5I refractory erectile dysfunction: a randomized double-blind sham-controlled clinical trial
Vinay, J. I., Moreno‐Mendoza, D., Rajmil, O., Ruíz-Castañé, E., & Sánchez‐Curbelo, J. (2020) · World Journal of Urology · doi:10.1007/s00345-020-03373-y · Cited by 45 · see citing works
Canadian Urological Association guideline: Erectile dysfunction
Domes, T., Najafabadi, B. T., Roberts, M., Campbell, J. D., Flannigan, R. K., Bach, P. V., Patel, P., Langille, G. M., Krakowsky, Y., & Violette, P. D. (2021) · Canadian Urological Association Journal · doi:10.5489/cuaj.7572 · Cited by 45 · see citing works
Guidelines for Sexual Health Care for Prostate Cancer Patients: Recommendations of an International Panel
Wittmann, D. A., Mehta, A., McCaughan, E., Faraday, M. M., Duby, A. A., Matthew, A., Incrocci, L., Burnett, A. L. “., Nelson, C. J., Elliott, S., et al. (2022) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2022.08.197 · Cited by 44 · see citing works
Vasculogenic Erectile Dysfunction: The Impact of Diet and Lifestyle
Ostfeld, R. J., Allen, K., Aspry, K. E., Brandt, E. J., Spitz, A., Liberman, J. N., Belardo, D., O’Keefe, J. H., Aggarwal, M., Miller, M. J., et al. (2020) · The American Journal of Medicine · doi:10.1016/j.amjmed.2020.09.033 · Cited by 51 · see citing works
Penile Implant Surgery Satisfaction Assessment
Manfredi, C., Fortier, E., Faix, A., & Martínez‐Salamanca, J. I. (2021) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2021.03.007 · Cited by 42 · see citing works
Electromagnetic Low-Intensity Extracorporeal Shock Wave Therapy in Patients with Erectile Dysfunction: A Sham-Controlled, Double-Blind, Randomized Prospective Study
Kim, K. S., Jeong, H. C., Choi, S. W., Choi, Y. S., Cho, H. J., Ha, U., Hong, S., Lee, J. Y., Lee, S. W., Ahn, S. T., et al. (2019) · The World Journal of Men s Health · doi:10.5534/wjmh.190130 · Cited by 42 · see citing works
Erectile dysfunction: a global review of intracavernosal injectables
Duncan, C., Omran, G., Teh, J., Davis, N. F., Bolton, D. M., & Lawrentschuk, N. (2019) · World Journal of Urology · doi:10.1007/s00345-019-02727-5 · Cited by 54 · see citing works
Infectious Adverse Events Following the Placement of a Penile Prosthesis: A Systematic Review
Mahon, J., Dornbier, R. A., Wegrzyn, G. H., Faraday, M. M., Sadeghi‐Nejad, H., Hakim, L., & McVary, K. T. (2019) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2019.07.005 · Cited by 40 · see citing works
Oncofertility in adult and pediatric populations: options and barriers
Halpern, J. A., Das, A., Faw, C. A., & Brannigan, R. E. (2020) · Translational Andrology and Urology · doi:10.21037/tau.2019.09.27 · Cited by 39 · see citing works
Examining Online Traffic Patterns to Popular Direct-To-Consumer Websites for Evaluation and Treatment of Erectile Dysfunction
Wackerbarth, J. J., Fantus, R. J., Darves-Bornoz, A. L., Hehemann, M. C., Helfand, B. T., Keeter, M. K., Brannigan, R. E., Bennett, N., & Halpern, J. A. (2021) · Sexual Medicine · doi:10.1016/j.esxm.2020.100289 · Cited by 42 · see citing works
Physical activity as an adjunct treatment for erectile dysfunction
Allen, M. S. (2019) · Nature Reviews Urology · doi:10.1038/s41585-019-0210-6 · Cited by 38 · see citing works
Direct-To-Consumer Internet Prescription Platforms Overlook Crucial Pathology Found During Traditional Office Evaluation of Young Men With Erectile Dysfunction
Shahinyan, R. H., Amighi, A., Carey, A. N., Yoffe, D. A., Hodge, D. C., Pollard, M. E., Nork, J., Mills, J. N., & Eleswarapu, S. V. (2020) · Urology · doi:10.1016/j.urology.2020.03.067 · Cited by 38 · see citing works
Prevalence of Erectile Dysfunction in Patients With End-Stage Renal Disease: A Systematic Review and Meta-Analysis
Pyrgidis, N., Mykoniatis, I., Nigdelis, M. P., Kalyvianakis, D., Memmos, E., Sountoulides, P., & Hatzichristou, D. G. (2020) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2020.10.012 · Cited by 37 · see citing works
Penile implant surgery-managing complications
Cayetano-Alcaráz, A. A., Yassin, M., Desai, A., Tharakan, T., Tsampoukas, G., Zurli, M., & Minhas, S. (2021) · Faculty Reviews · doi:10.12703/r/10-73 · Cited by 37 · see citing works
Differences in the prevalence of erectile dysfunction between novel subgroups of recent-onset diabetes
Maalmi, H., Herder, C., Bönhof, G. J., Straßburger, K., Zaharia, O., Rathmann, W., Burkart, V., Szendroedi, J., Roden, M., Ziegler, D., et al. (2021) · Diabetologia · doi:10.1007/s00125-021-05607-z · Cited by 37 · see citing works
Erectile dysfunction links to cardiovascular disease—defining the clinical value
Orimoloye, O. A., Feldman, D. I., & Blaha, M. J. (2019) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2019.01.002 · Cited by 36 · see citing works
Intra‐cavernous injection of BOTOX® (50 and 100 Units) for treatment of vasculogenic erectile dysfunction: Randomized controlled trial
El‐Shaer, W., Ghanem, H. M., Diab, T., Abou-Taleb, A., & Kandeel, W. (2021) · Andrology · doi:10.1111/andr.13010 · Cited by 36 · see citing works
Needs and Expectations of Patients with Erectile Dysfunction: An Update on Pharmacological Innovations in Phosphodiesterase Type 5 Inhibition with Focus on Sildenafil
Jannini, E. A., & Droupy, S. (2018) · Sexual Medicine · doi:10.1016/j.esxm.2018.10.005 · Cited by 34 · see citing works
Cigarette smoking and erectile dysfunction: an updated review with a focus on pathophysiology, e-cigarettes, and smoking cessation
Allen, M. S., & Tostes, R. C. (2023) · Sexual Medicine Reviews · doi:10.1093/sxmrev/qeac007 · Cited by 34 · see citing works
The Use of Antiseptic Solutions in the Prevention and Management of Penile Prosthesis Infections: A Review of the Cytotoxic and Microbiological Effects of Common Irrigation Solutions
Pan, S., Rodríguez, D., Thirumavalavan, N., Gross, M. S., Eid, J. F., Mulcahy, J. J., & Munarriz, R. M. (2019) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2019.03.271 · Cited by 34 · see citing works
Erectile dysfunction in patients undergoing multiple attempts at hypospadias repair: Etiologies and concerns
Husmann, D. A. (2020) · Journal of Pediatric Urology · doi:10.1016/j.jpurol.2020.12.002 · Cited by 34 · see citing works
Low-intensity extracorporeal shock wave therapy for erectile dysfunction: Myths and realities
Bocchino, A. C., Pezzoli, M., Martínez‐Salamanca, J. I., Russo, G. I., Giudice, A. L., & Cocci, A. (2023) · Korean journal of urology · doi:10.4111/icu.20220327 · Cited by 35 · see citing works
An update on the best approaches to prevent complications in penile prosthesis recipients
Krzastek, S. C., & Smith, R. P. (2019) · Therapeutic Advances in Urology · doi:10.1177/1756287218818076 · Cited by 33 · see citing works
A Systematic Review of Human Trials Using Stem Cell Therapy for Erectile Dysfunction
Lokeshwar, S. D., Patel, P., Shah, S. M., & Ramasamy, R. (2019) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2019.08.003 · Cited by 33 · see citing works
A Systematic Review of Pelvic Floor Muscle Training for Erectile Dysfunction After Prostatectomy and Recommendations to Guide Further Research
Wong, C., Louie, D. R., & Beach, C. (2020) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2020.01.008 · Cited by 37 · see citing works
Immediate preoperative blood glucose and hemoglobin a1c levels are not predictive of postoperative infections in diabetic men undergoing penile prosthesis placement
Osman, M. M., Huynh, L. M., El‐Khatib, F. M., Towe, M. M., Su, H.-W., Andrianne, R., Barton, G. J., Broderick, G. A., Burnett, A. L. “., Campbell, J. D., et al. (2020) · International Journal of Impotence Research · doi:10.1038/s41443-020-0261-5 · Cited by 33 · see citing works
Etiology of Erectile Dysfunction and Duration of Symptoms in Patients Undergoing Penile Prosthesis: A Systematic Review
Bajic, P., Mahon, J., Faraday, M. M., Sadeghi‐Nejad, H., Hakim, L., & McVary, K. T. (2019) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2019.05.003 · Cited by 32 · see citing works
International Continence Society (ICS) report on the terminology for sexual health in men with lower urinary tract (LUT) and pelvic floor (PF) dysfunction
Kocjancic, E., Chung, E., Garzón, J. H. Á., Haylen, B. T., Iacovelli, V., Jaunarena, J. H., Locke, J. A., Millman, A. L., Nahon, I., Ohlander, S. J., et al. (2022) · Neurourology and Urodynamics · doi:10.1002/nau.24846 · Cited by 35 · see citing works
The role of imaging in the diagnosis and management of Peyronie's disease
Parmar, M., Masterson, J. M., & Masterson, T. A. (2020) · Current Opinion in Urology · doi:10.1097/mou.0000000000000754 · Cited by 30 · see citing works
LncRNA MALAT1 facilitates BM-MSCs differentiation into endothelial cells via targeting miR-206/VEGFA axis
Sun, X., Luo, L., & Li, J. (2020) · Cell Cycle · doi:10.1080/15384101.2020.1829799 · Cited by 30 · see citing works
The potential of platelet-rich plasma injections and stem cell therapy for penile rejuvenation
Israeli, J. M., Lokeshwar, S. D., Efimenko, I. V., Masterson, T. A., & Ramasamy, R. (2022) · International Journal of Impotence Research · doi:10.1038/s41443-021-00482-z · Cited by 30 · see citing works
“The AUA Guidelines for Management and Treatment of Erectile Dysfunction consider SCT and PRP as investigational (conditional recommendation; evidence level: grade C) and experimental (expert opinion), respectively [64].”
Method
Adverse reactions of PDE5 inhibitors: An analysis of the World Health Organization pharmacovigilance database
Lui, J. L., Shaw, N. M., Abbasi, B., Hakam, N., & Breyer, B. N. (2023) · Andrology · doi:10.1111/andr.13430 · Cited by 30 · see citing works
An overview of the history, current strategies, and potential future treatment approaches in erectile dysfunction: a comprehensive review
Langarizadeh, M. A., Salary, A., Tavakoli, M. R., Nejad, B. G., Fadaei, S., Jahani, Z., & Forootanfar, H. (2023) · Sexual Medicine Reviews · doi:10.1093/sxmrev/qead014 · Cited by 30 · see citing works
Papaverine hydrochloride containing nanostructured lyotropic liquid crystal formulation as a potential drug delivery system for the treatment of erectile dysfunction
Berkó, S., Zsikó, S., Deák, G., Gácsi, A., Kovács, A., Budai-Szűcs, M., Pajor, L., Bajory, Z., & Csányi, E. (2018) · Drug Design Development and Therapy · doi:10.2147/dddt.s168218 · Cited by 28 · see citing works
Vascular endothelium is the basic way for stem cells to treat erectile dysfunction: a bibliometric study
Zou, H., Zhang, X., Chen, W., Tao, Y., Li, B., Liu, H., Wang, R., & Zhao, J. (2023) · Cell Death Discovery · doi:10.1038/s41420-023-01443-9 · Cited by 27 · see citing works
Platelet-rich plasma intracavernosal injections for the treatment of primary organic erectile dysfunction: a systematic review and meta-analysis of contemporary controlled studies
Panunzio, A., Labate, C., Zacheo, F., Orlando, R., Rizzo, F. L., Porcaro, A., Migliorini, F., Pagliarulo, V., & Tafuri, A. (2023) · International journal of impotence research · doi:10.1038/s41443-023-00798-y · Cited by 29 · see citing works
Erectile Dysfunction: Update on Clinical Management
Capogrosso, P., Albersen, M., Burnett, A. L., Çakır, Ö. O., Dehò, F., Morgado, L. A. R., Mulhall, J. P., Salonia, A., Sarıkaya, A. F., Satchi, M., et al. (2025) · European Urology · doi:10.1016/j.eururo.2025.05.004 · Cited by 28 · see citing works
Safety and Efficacy of Intracavernosal Injections of AbobotulinumtoxinA (Dysport®) as Add on Therapy to Phosphosdiesterase Type 5 Inhibitors or Prostaglandin E1 for Erectile Dysfunction—Case Studies
Giuliano, F., Joussain, C., & Denys, P. (2019) · Toxins · doi:10.3390/toxins11050283 · Cited by 26 · see citing works
Yohimbine as a treatment for erectile dysfunction: A systematic review and meta-analysis
Wibowo, D. N. S. A., Soebadi, D. M., & Soebadi, M. A. (2021) · Urology Research and Practice · doi:10.5152/tud.2021.21206 · Cited by 26 · see citing works
An updated meta-analysis of prostatic arterial embolization versus transurethral resection of the prostate in the treatment of benign prostatic hyperplasia
Xu, X., Li, J., Huang, X., & Liu, Q. (2019) · World Journal of Urology · doi:10.1007/s00345-019-03044-7 · Cited by 26 · see citing works
Sexual Health Inventory for Men Questionnaire as a Screening Method for Erectile Dysfunction in a General Urology Clinic
Alwaal, A., Awad, M. A., Boggs, N., Kuzbel, J., & Snoad, B. (2020) · Sexual Medicine · doi:10.1016/j.esxm.2020.08.002 · Cited by 25 · see citing works
Hyperprolactinemia and male sexual function: focus on erectile dysfunction and sexual desire
Corona, G., Rastrelli, G., Bianchi, N., Sparano, C., Sforza, A., Vignozzi, L., & Maggi, M. (2023) · International Journal of Impotence Research · doi:10.1038/s41443-023-00717-1 · Cited by 25 · see citing works
Icariin modulates eNOS activity via effect on post‐translational protein‐protein interactions to improve erectile function of spontaneously hypertensive rats
Liu, Q., Yang, Z., Jiang, J., & Jiang, R. (2020) · Andrology · doi:10.1111/andr.12875 · Cited by 24 · see citing works
An Analysis of a Commercial Database on the Use of Erectile Dysfunction Treatments for Men With Employer-Sponsored Health Insurance
Burnett, A. L. “., Rojanasarot, S., & Amorosi, S. L. (2020) · Urology · doi:10.1016/j.urology.2020.11.051 · Cited by 24 · see citing works
Effect of Phosphodiesterase-5 Inhibitors on the Treatment of Male Infertility: A Systematic Review and Meta-Analysis
Dong, L., Zhang, X., Yan, X., Shen, Y., Li, Y., & Yu, X. (2021) · The World Journal of Men s Health · doi:10.5534/wjmh.200155 · Cited by 24 · see citing works
Medications Most Commonly Associated with Erectile Dysfunction: Evaluation of the Food and Drug Administration National Pharmacovigilance Database
Kaplan-Marans, E., Sandozi, A., Martinez, M., Lee, J., Schulman, A. A., & Khurgin, J. L. (2022) · Sexual Medicine · doi:10.1016/j.esxm.2022.100543 · Cited by 24 · see citing works
Modern treatment strategies for penile prosthetics in Peyronie's disease: a contemporary clinical review
Levine, L. A., Ziegelmann, M., & Farrell, M. R. (2019) · Asian Journal of Andrology · doi:10.4103/aja.aja_81_19 · Cited by 24 · see citing works
A Review of Current and Emerging Therapeutic Options for Erectile Dysfunction
Chung, E. (2019) · Medical Sciences · doi:10.3390/medsci7090091 · Cited by 24 · see citing works
Male Sexual and Reproductive Health—Does the Urologist Have a Role in Addressing Gender Inequality in Life Expectancy?
Tharakan, T., Bettocchi, C., Carvalho, J., Corona, G., Joensen, U. N., Jones, H. T., Kadıoğlu, A., Martínez‐Salamanca, J. I., Şerefoğlu, E. C., Verze, P., et al. (2019) · European Urology Focus · doi:10.1016/j.euf.2019.10.009 · Cited by 23 · see citing works
Low‐intensity extracorporeal shockwave therapy for diabetic men with erectile dysfunction: A systematic scoping review
Mason, M. M., Pai, R., Masterson, J. M., Lokeshwar, S. D., Chu, K. Y., & Ramasamy, R. (2022) · Andrology · doi:10.1111/andr.13197 · Cited by 23 · see citing works
Efficient use of penile Doppler ultrasound for investigating men with erectile dysfunction
Flores, J. M., West, M., & Mulhall, J. P. (2024) · The Journal of Sexual Medicine · doi:10.1093/jsxmed/qdae070 · Cited by 22 · see citing works
The Princeton IV Consensus Recommendations for the Management of Erectile Dysfunction and Cardiovascular Disease
Köhler, T., Kloner, R. A., Rosen, R. C., Burnett, A. L., Blaha, M. J., Ganz, P., Goldstein, I., Kim, N. N., Lue, T. F., McVary, K. T., et al. (2024) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2024.06.002 · Cited by 22 · see citing works
European Academy of Neurology ( EAN )/European Federation of Autonomic Societies ( EFAS )/International Neuro‐Urology Society ( INUS ) Guidelines for Practising Neurologists on the Assessment and Treatment of Neurogenic Urinary and Sexual Symptoms ( NEUROGED Guidelines)
Panicker, J. N., Fanciulli, A., Skorić, M. K., Kaplan, T., Aleksovska, K., Adamec, I., Averbeck, M. A., Campese, N., Guaraldi, P., Leys, F., et al. (2025) · European Journal of Neurology · doi:10.1111/ene.70119 · Cited by 22 · see citing works
Canadian Urological Association clinical practice guideline on testosterone deficiency in men: Evidence-based Q&A
Grober, E. D., Krakowsky, Y., Khera, M., Holmes, D. T., Jc, L., Grantmyre, J. E., Patel, P., Bebb, R. A., Fitzpatrick, R., Campbell, J. D., et al. (2021) · Canadian Urological Association Journal · doi:10.5489/cuaj.7252 · Cited by 25 · see citing works
Quality and readability of online patient information on treatment for erectile dysfunction
Pattenden, T. A., Raleigh, R. A., Pattenden, E., & Thangasamy, I. (2021) · BJUI Compass · doi:10.1002/bco2.87 · Cited by 22 · see citing works
Ginseng for Erectile Dysfunction: A Cochrane Systematic Review
Lee, H. W., Lee, M. S., Kim, T., Alræk, T., Zaslawski, C., Kim, J. W., & Moon, D. G. (2021) · The World Journal of Men s Health · doi:10.5534/wjmh.210071 · Cited by 22 · see citing works
Erectile Dysfunction in Adolescents and Young Adults
Pantazis, A., Franco, I., & GITLIN, J. S. (2024) · Current Urology Reports · doi:10.1007/s11934-024-01213-9 · Cited by 21 · see citing works

The Role of Vacuum Device Therapy in the Management of Erectile Dysfunction
Lewis, R. W., & Newell, M. M. (2005) · US Endocrinology · doi:10.17925/use.2005.00.01.93 · Cited by 2 · see citing works
AUA Updates Guidelines on Management of Erectile Dysfunction
Coughlin, L. (2006) · American family physician · Cited by 1 · see citing works
EAU Guidelines on Erectile Dysfunction: An Update
Wespes, E., Amar, E., Hatzichristou, D. G., Hatzimouratidis, K., Montorsi, F., PRYOR, J. P., & Vardi, Y. (2006) · European Urology · doi:10.1016/j.eururo.2006.01.028 · Cited by 290 · see citing works
Guidelines for Treating Erectile Dysfunction Issued
Skolnick, A. A. (1997) · JAMA · doi:10.1001/jama.1997.03540250015007 · Cited by 2 · see citing works
A simplified approach to the treatment of erectile dysfunction Based on the Canadian Urology Association Erectile Dysfunction Guidelines
Brock, G. B. (2002) · Journal of Sexual & Reproductive Medicine · doi:10.4172/1488-5069.1000028 · Cited by 3 · see citing works

Authors: Burnett, A. L., Nehra, A., Breau, R. H., Culkin, D. J., Faraday, M. M., Hakim, L. S., Heidelbaugh, J., Khera, M., McVary, K. T., Miner, M. M., Nelson, C. J., Sadeghi-Nejad, H., Seftel, A. D., & Shindel, A. W.
Affiliations: American Urological Association (US)
American Urological Association Education and Research, Inc., Linthicum, Maryland
ORCID: Burnett, Arthur L.
Breau, Rodney H.
Culkin, Daniel J.
Khera, Mohit
McVary, Kevin T.
Miner, Martin M.
Nelson, Christian J.
Shindel, Alan W.
Venue: Journal of Urology
Publisher: Ovid Technologies (Wolters Kluwer Health)
Published: 2018-09
Volume: 200
Issue: 3
Pages: 633-641
ISSN: 0022-5347 (ISSN-L)
1527-3792
DOI: 10.1016/j.juro.2018.05.004
OpenAlex: W2801324609
Cited by: 949
References: 53
Citations by year: 2026: 162 · 2025: 127 · 2024: 144 · 2023: 140 · 2022: 100 · 2021: 108 · 2020: 86 · 2019: 70 · 2018: 8 · 2017: 1 · 2016: 1
FWCI: 53.14
Type: journal article
Language: en
Update notices: erratum (2022-03-01)
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: The Journal of Urology (publishedVersion)
PubMed (publishedVersion)
eScholarship (California Digital Library) (acceptedVersion)
eScholarship (California Digital Library) (submittedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
Health Sciences › Medicine › Urology › Urological Disorders and Treatments
Health Sciences › Medicine › Urology › Urinary Bladder and Prostate Research
Keywords: erectile dysfunction, diagnosis, treatment, shared decision-making, first-line therapy, treatment algorithm, patient education, evidence-based recommendations
MeSH terms: Clinical Decision-Making, Decision Making, Humans, Erectile Dysfunction, Male, Patient Participation, Societies, Medical, Urology, Critical Pathways

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Erectile dysfunction: AUA guideline

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