A systematic review of the psychosocial outcomes associated with erectile dysfunction: does the impact of erectile dysfunction extend beyond a man's inability to have sex?

McCabe, Marita P.; Althof, Stanley E.

doi:10.1111/jsm.12374

Cited by 140Sexual function and dysfunction studiesUrological Disorders and TreatmentsSexuality, Behavior, and Technology

A systematic review of the psychosocial outcomes associated with erectile dysfunction: does the impact of erectile dysfunction extend beyond a man's inability to have sex?

McCabe, Marita P., Althof, Stanley E.·2014·The Journal of Sexual Medicine

DOI 10.1111/jsm.12374

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Abstract

AIM: The aim of this study was to report and analyze the published data from randomized controlled trials (RCTs) for (i) the psychosocial outcomes associated with erectile dysfunction (ED) before treatment with a phosphodiesterase type 5 (PDE5) inhibitor; and (ii) the change in psychosocial outcomes after the use of a PDE5 inhibitor in men with ED. METHODS: The method used was a prospectively designed systematic literature review of publications reported in MEDLINE via PubMed, EMBASE, the Cochrane Library, Science Citation Index Expanded, and PsychINFO from January 1, 1995 to May 14, 2012. MAIN OUTCOME MEASURES: The main outcome measures were scores on psychosocial measures in men who were treated for ED with a PDE5 inhibitor before and after treatment. RESULTS: A total of 1,714 publications were retrieved; 1,674 publications were excluded because they did not meet the design requirements of the review, and 40 publications (32 RCTs) were retained. Before treatment, men who participated in clinical trials reported relatively good quality of life and overall relationships, but poor sexual relationships and sexual satisfaction, diminished confidence, low self-esteem, and symptoms of depression. After treatment, there were significant improvements from baseline in most of these measures, except for overall life satisfaction and overall relationship satisfaction. CONCLUSIONS: ED and the treatment of ED are associated with substantially broader aspects of a man's life than just erectile functioning. This review demonstrates the importance of evaluating the psychosocial factors associated with ED and its treatment, and the importance of using standardized scales to conduct this evaluation. Further research is needed to better understand the mechanisms underlying the reciprocal relationships among physical and psychological functioning in men with ED.

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A disruption of the sexual response causes considerable distress in men and their partners.
“Furthermore, a disruption of the sexual response causes considerable distress in men and their partners.6, 7, 8”
From A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM) (2021) · cites this paper as [6]

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McVary, K. T., Kaufman, J. M., Young, J. M., & Tseng, L. (2007) · International Journal of Clinical Practice · doi:10.1111/j.1742-1241.2007.01585.x · Cited by 16 · see citing works
Self-Esteem, Confidence, and Relationships in Brazilian Men with Erectile Dysfunction Receiving Sildenafil Citrate: A Randomized, Parallel-Group, Double-Blind, Placebo-Controlled Study in Brazil
Glina, S., Damião, R., Abdo, C. H. N., Afif‐Abdo, J., Tseng, L., & Stecher, V. J. (2009) · The Journal of Sexual Medicine · doi:10.1111/j.1743-6109.2008.01026.x · Cited by 14 · see citing works
A Multicenter, Double-blind, Placebo-controlled Trial to Assess The Efficacy of Sildenafil Citrate in Men With Unrecognized Erectile Dysfunction
Shabsigh, R., Kaufman, J. M., Magee, M., Creanga, D. L., Russell, D., & Budhwani, M. (2010) · Urology · doi:10.1016/j.urology.2010.03.017 · Cited by 12 · see citing works
Analysis of single items on the Self‐Esteem And Relationship questionnaire in men treated with sildenafil citrate for erectile dysfunction: results of two double‐blind, placebo‐controlled trials
Cappelleri, J. C., Althof, S. E., O’Leary, M. P., Tseng, L., & Groups, U. A. I. S. S. (2008) · British Journal of Urology · doi:10.1111/j.1464-410x.2007.07354.x · Cited by 12 · see citing works
Self-citation
Hardness, function, emotional well-being, satisfaction and the overall sexual experience in men using 100-mg fixed-dose or flexible-dose sildenafil citrate
Ströberg, P., Kaminetsky, J. C., Park, N. C., Goldfischer, E. R., Creanga, D. L., & Stecher, V. J. (2010) · International Journal of Impotence Research · doi:10.1038/ijir.2010.17 · Cited by 11 · see citing works
Self-esteem, confidence and relationship satisfaction in men with erectile dysfunction: a randomized, parallel-group, double-blind, placebo-controlled study of sildenafil in Mexico
Farca, E. Z., Víctor, F.-V., Moy-Eransus, C., Bravo, Á. O., Tseng, L.-J., & Stecher, V. J. (2008) · International Journal of Impotence Research · doi:10.1038/ijir.2008.24 · Cited by 11 · see citing works
Evaluation of self-esteem in males with erectile dysfunction treated with viagra. Analysis of a Spanish patients group selected from a multicenter, international study
Martínez-Jabaloyas, J. M., Moncada, I., Rodriguez-Vela, L., Gutiérrez, P. R., & de Chaves, J. R. G. (2010) · Actas Urológicas Españolas (English Edition) · doi:10.1016/s2173-5786(10)70172-4 · Cited by 7 · see citing works
Evaluación de la autoestima en varones con disfunción eréctil tratados con sildenafilo. Análisis de un grupo de pacientes españoles procedentes de un estudio multicéntrico internacional
Martínez-Jabaloyas, J. M., Moncada, I., Rodriguez-Vela, L., Gutiérrez, P. R., & Chaves, J. (2010) · Actas Urológicas Españolas · doi:10.1016/j.acuro.2010.03.023 · Cited by 6 · see citing works

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Erectile dysfunction: AUA guideline
Burnett, A. L., Nehra, A., Breau, R. H., Culkin, D. J., Faraday, M. M., Hakim, L. S., Heidelbaugh, J., Khera, M., McVary, K. T., Miner, M. M., et al. (2018) · Journal of Urology · doi:10.1016/j.juro.2018.05.004 · Cited by 949 · see citing works
Erectile dysfunction
Yafi, F. A., Jenkins, L., Albersen, M., Corona, G., Isidori, A. M., Goldfarb, S., Maggi, M., Nelson, C. J., Parish, S., Salonia, A., et al. (2016) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2016.3 · Cited by 853 · see citing works
Erectile Dysfunction in Young Men—A Review of the Prevalence and Risk Factors
Nguyen, H. M. T., Gabrielson, A. T., & Hellstrom, W. J. G. (2017) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2017.05.004 · Cited by 352 · see citing works
Couples’ Sexual Communication and Dimensions of Sexual Function: A Meta-Analysis
Mallory, A. B., Stanton, A. M., & Handy, A. B. (2019) · The Journal of Sex Research · doi:10.1080/00224499.2019.1568375 · Cited by 138 · see citing works
Sexual Health Implications of COVID-19 Pandemic
Pennanen-Iire, C., Prereira-Lourenço, M., Padoa, A., Ribeirinho, A., Samico, A., Gressler, M., Jatoi, N.-A., Mehrad, M., & Girard, A. (2020) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2020.10.004 · Cited by 155 · see citing works
Erectile dysfunction in fit and healthy young men: psychological or pathological?
Rastrelli, G., & Maggi, M. (2017) · Translational Andrology and Urology · doi:10.21037/tau.2016.09.06 · Cited by 123 · see citing works
Erectile dysfunction, masculinity, and psychosocial outcomes: a review of the experiences of men after prostate cancer treatment
Chambers, S. K., Chung, E., Wittert, G., & Hyde, M. K. (2017) · Translational Andrology and Urology · doi:10.21037/tau.2016.08.12 · Cited by 119 · see citing works
A Psychosocial Approach to Erectile Dysfunction: Position Statements from the European Society of Sexual Medicine (ESSM)
Dewitte, M., Bettocchi, C., Carvalho, J., Corona, G., Flink, I., Limoncin, E., Pascoal, P., Reisman, Y., & Van Lankveld, J. (2021) · Sexual Medicine · doi:10.1016/j.esxm.2021.100434 · Cited by 97 · see citing works
Current Diagnosis and Management of Erectile Dysfunction
Pastuszak, A. W. (2014) · Current Sexual Health Reports · doi:10.1007/s11930-014-0023-9 · Cited by 87 · see citing works
Combination of psychological intervention and phosphodiesterase-5 inhibitors for erectile dysfunction: A narrative review and meta-analysis
Schmidt, H. M., Munder, T., Gerger, H., Frühauf, S., & Barth, J. (2014) · The Journal of Sexual Medicine · doi:10.1111/jsm.12520 · Cited by 84 · see citing works
Novel Emerging Therapies for Erectile Dysfunction
Kim, S., Cho, M. C., Cho, S. Y., Chung, H., & Rajasekaran, M. R. (2020) · The World Journal of Men s Health · doi:10.5534/wjmh.200007 · Cited by 78 · see citing works
Meta-Analysis of Prevalence of Erectile Dysfunction in Mainland China: Evidence Based on Epidemiological Surveys
Wang, W., Fan, J., Huang, G., Zhu, X. M., Tian, Y., Tan, H., & Su, L. (2016) · Sexual Medicine · doi:10.1016/j.esxm.2016.10.001 · Cited by 69 · see citing works
Association of Concussion Symptoms With Testosterone Levels and Erectile Dysfunction in Former Professional US-Style Football Players
Grashow, R. G., Weisskopf, M. G., Miller, K. K., Nathan, D. M., ZAFONTE, R. D., Speizer, F. E., Courtney, T. K., Baggish, A. L., Taylor, H. A., Pascual‐Leone, Á., et al. (2019) · JAMA Neurology · doi:10.1001/jamaneurol.2019.2664 · Cited by 46 · see citing works
Non-pharmacological and non-surgical strategies to promote sexual recovery for men with erectile dysfunction
Wassersug, R., & Wibowo, E. (2017) · Translational Andrology and Urology · doi:10.21037/tau.2017.04.09 · Cited by 45 · see citing works
Primary organic versus primary psychogenic erectile dysfunction: Findings from a real‐life cross‐sectional study
Pozzi, E., Fallara, G., Capogrosso, P., Boeri, L., Belladelli, F., Corsini, C., da Costa, A. G., Candela, L., Cignoli, D., Cazzaniga, W., et al. (2022) · Andrology · doi:10.1111/andr.13212 · Cited by 43 · see citing works
Factors associated with anxiety and depression in patients with erectile dysfunction: a cross-sectional study
Xiao, Y., Xie, T., Peng, J., Zhou, X., Long, J., Yang, M., Zhu, H., & Yang, J. Y. (2023) · BMC Psychology · doi:10.1186/s40359-023-01074-w · Cited by 48 · see citing works
Factors Associated With Erectile Dysfunction and the Peyronie's Disease Questionnaire in Patients With Peyronie Disease
Serefoglu, E. C., Smith, T. M., Kaufman, G. J., Liu, G., Yafi, F. A., & Hellstrom, W. J. G. (2017) · Urology · doi:10.1016/j.urology.2017.05.029 · Cited by 39 · see citing works
Relationship Between Nutritional Status and Quality of Life in Patients with Lung Cancer
Polański, J., Jankowska‐Polańska, B., & Mazur, G. J. (2021) · Cancer Management and Research · doi:10.2147/cmar.s287551 · Cited by 38 · see citing works
Sexual dysfunction and relationship stress: how does this association vary for men and women?
McCabe, M. P., & Connaughton, C. (2016) · Current Opinion in Psychology · doi:10.1016/j.copsyc.2016.05.007 · Cited by 36 · see citing works
Self-citation
Can lifestyle modification affect men’s erectile function?
Hehemann, M. C., & Kashania, J. A. (2016) · Translational Andrology and Urology · doi:10.21037/tau.2016.02.05 · Cited by 34 · see citing works
Association Between Opioid Use and Risk of Erectile Dysfunction: A Systematic Review and Meta-Analysis
Zhao, S., Deng, T., Luo, L., Wang, J., Li, E., Liu, L., Li, F., Luo, J., & Zhao, Z. (2017) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2017.08.010 · Cited by 35 · see citing works
Current epidemiology of erectile dysfunction, an update
Colson, M.-H., Cuzin, B., Faix, A., Grellet, L., & Huyghes, É. (2018) · Sexologies · doi:10.1016/j.sexol.2018.01.018 · Cited by 34 · see citing works
A Place for Sexual Dysfunctions in an Empirical Taxonomy of Psychopathology
Forbes, M. K., Baillie, A., Eaton, N. R., & Krueger, R. F. (2017) · The Journal of Sex Research · doi:10.1080/00224499.2016.1269306 · Cited by 34 · see citing works
Sexual Dysfunction in Inflammatory Bowel Disease
Ghazi, L. J., Patil, S. A., & Cross, R. K. (2014) · Inflammatory Bowel Diseases · doi:10.1097/mib.0000000000000260 · Cited by 32 · see citing works
Management of erectile dysfunction after prostate cancer treatment: cross-sectional surveys of the perceptions and experiences of patients and healthcare professionals in the UK
Dyer, A., Kirby, M. G., White, I. D., & Cooper, A. M. (2019) · BMJ Open · doi:10.1136/bmjopen-2019-030856 · Cited by 32 · see citing works
Medical Help-Seeking for Sexual Concerns in Prostate Cancer Survivors
Hyde, M. K., Zajdlewicz, L., Wootten, A. C., Nelson, C. J., Lowe, A., Dunn, J. C., & Chambers, S. K. (2016) · Sexual Medicine · doi:10.1016/j.esxm.2015.12.004 · Cited by 30 · see citing works
Efficacy of Continuous Dosing of Tadalafil Once Daily vs Tadalafil On Demand in Clinical Subgroups of Men with Erectile Dysfunction: A Descriptive Comparison Using the Integrated Tadalafil Databases
Brock, G. B., Ni, X., Oelke, M., Mulhall, J. P., Rosenberg, M. T., Seftel, A. D., D’Souza, D. N., & Barry, J. (2016) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2016.02.171 · Cited by 29 · see citing works
Association Between HIV Infection and Prevalence of Erectile Dysfunction: A Systematic Review and Meta-Analysis
Luo, L., Deng, T., Zhao, S., Li, E., Liu, L., Li, F., Wang, J., & Zhao, Z. (2017) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2017.07.001 · Cited by 28 · see citing works
Erectile Dysfunction: Update on Clinical Management
Capogrosso, P., Albersen, M., Burnett, A. L., Çakır, Ö. O., Dehò, F., Morgado, L. A. R., Mulhall, J. P., Salonia, A., Sarıkaya, A. F., Satchi, M., et al. (2025) · European Urology · doi:10.1016/j.eururo.2025.05.004 · Cited by 28 · see citing works
Cognitive Behavioral Sex Therapy: An Emerging Treatment Option for Nonorganic Erectile Dysfunction in Young Men: A Feasibility Pilot Study
Bilal, A., & Abbasi, N. U. H. (2020) · Sexual Medicine · doi:10.1016/j.esxm.2020.05.005 · Cited by 26 · see citing works
Prevalence and Characteristics of Erectile Dysfunction in Obstructive Sleep Apnea Patients
Chen, F., Yang, Y., Chen, L., Guo, R., Liu, H., Li, C., Wang, Y., Dong, P., & Li, Y. (2022) · Frontiers in Endocrinology · doi:10.3389/fendo.2022.812974 · Cited by 26 · see citing works
Clinical Profile of Young Patients with Erectile Dysfunction: Preliminary Findings of a Real-life Cross-sectional Study
Pozzi, E., Capogrosso, P., Chierigo, F., Pederzoli, F., Ventimiglia, E., Boeri, L., Frego, N., Moretti, D., Dehò, F., Montorsi, F., et al. (2018) · European Urology Focus · doi:10.1016/j.euf.2018.10.003 · Cited by 25 · see citing works
Effects of renal transplantation on erectile dysfunction: a systematic review and meta-analysis
Rahman, I. A., Rasyid, N., Birowo, P., & Atmoko, W. (2021) · International Journal of Impotence Research · doi:10.1038/s41443-021-00419-6 · Cited by 24 · see citing works
Chronic periodontitis and the risk of erectile dysfunction: a systematic review and meta-analysis
Liu, L. H., Li, E. M., Zhong, S., Li, Y. Q., Yang, Z., Kang, R., Zhao, S., Li, F. T., Wan, S. P., & Zhao, Z. (2016) · International Journal of Impotence Research · doi:10.1038/ijir.2016.43 · Cited by 22 · see citing works
Does underestimated penile size impact erectile function in healthy men?
Sanches, ⁠. C. F., Laranja, W. W., Alonso, J. C. C., Rejowski, R. F., Simões, F. A., & Reis, L. O. (2018) · International Journal of Impotence Research · doi:10.1038/s41443-018-0039-1 · Cited by 22 · see citing works
Association between chronic obstructive pulmonary disease and risk of erectile dysfunction: a systematic review and meta-analysis
Luo, L., Zhao, S., Wang, J., Liu, Y., Zhu, Z., Xiang, Q., & Zhao, Z. (2019) · International Journal of Impotence Research · doi:10.1038/s41443-019-0165-4 · Cited by 22 · see citing works
Should we tailor the clinical management of erectile dysfunction according to different ages?
Capogrosso, P., Ventimiglia, E., Boeri, L., Pozzi, E., Chierigo, F., Schifano, N., Abbate, C., Matloob, R., Montorsi, F., & Salonia, A. (2019) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2019.03.405 · Cited by 21 · see citing works
TrueNTH sexual recovery study protocol: a multi-institutional collaborative approach to developing and testing a web-based intervention for couples coping with the side-effects of prostate cancer treatment in a randomized controlled trial
Wittmann, D. A., Mehta, A., Northouse, L., Dunn, R. L., Braun, T., Duby, A. A., An, L. C., Arab, L., Bangs, R., Bober, S. L., et al. (2017) · BMC Cancer · doi:10.1186/s12885-017-3652-3 · Cited by 21 · see citing works
Association of erectile dysfunction with depression in patients with chronic viral hepatitis
Ma, B. O. (2015) · World Journal of Gastroenterology · doi:10.3748/wjg.v21.i18.5641 · Cited by 21 · see citing works
Socioeconomic status and barriers for contacting the general practitioner when bothered by erectile dysfunction: a population-based cross-sectional study
Rasmussen, S., Balasubramaniam, K., Jarbøl, D. E., Søndergaard, J., & Haastrup, P. (2020) · BMC Family Practice · doi:10.1186/s12875-020-01238-2 · Cited by 20 · see citing works
Premature ejaculation among Chinese urban men: prevalence and correlates
Niu, C., Ventus, D., Jern, P., & Santtila, P. O. (2023) · Sexual Medicine · doi:10.1093/sexmed/qfac015 · Cited by 20 · see citing works
An update on emerging drugs for the treatment of erectile dysfunction
Milenković, U., Campbell, J. D., Roussel, E., & Albersen, M. (2018) · Expert Opinion on Emerging Drugs · doi:10.1080/14728214.2018.1552938 · Cited by 19 · see citing works
Exploring the Role of Sexual Avoidance in Male Sexual Dysfunction
Stephenson, K. R. (2019) · The Journal of Sex Research · doi:10.1080/00224499.2019.1663480 · Cited by 19 · see citing works
Statistical Mediators of the Association Between Mindfulness and Sexual Experiences in Men with Impaired Sexual Function
Stephenson, K. R., & Welch, J. P. (2019) · Archives of Sexual Behavior · doi:10.1007/s10508-019-01467-2 · Cited by 19 · see citing works
Associations Between Altered Cerebral Activity Patterns and Psychosocial Disorders in Patients With Psychogenic Erectile Dysfunction: A Mediation Analysis of fMRI
Yin, T., Liu, Q., Ma, Z., Li, Z., Sun, R., Ren, F., Li, G., Huang, X., Chang, D., & Zhang, P. (2020) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2020.583619 · Cited by 19 · see citing works
The Association Between Sleep Disturbances and Erectile Dysfunction During the COVID-19 Pandemic
Andersen, M. L., & Tufik, S. (2021) · Sexual Medicine Reviews · doi:10.1016/j.sxmr.2021.12.001 · Cited by 18 · see citing works
The Race to Replace PDE5i: Recent Advances and Interventions to Treat or Manage Erectile Dysfunction: Evidence from Patent Landscape (2016–2021)
Islam, M. M., Naveen, N. R., Anitha, P., Prakash Goudanavar, S. O. P., Rao, G. K., Fattepur, S., Rahman, M. M., Shiroorkar, P. N., Habeebuddin, M., Meravanige, G., et al. (2022) · Journal of Clinical Medicine · doi:10.3390/jcm11113140 · Cited by 18 · see citing works
Male Urogenital System Mapped Onto the Sensory Cortex: Functional Magnetic Resonance Imaging Evidence
Allen, K. R., Wise, N. J., Frangos, E., & Komisaruk, B. R. (2020) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2019.12.007 · Cited by 18 · see citing works
Satisfaction with a Vacuum Constriction Device for Erectile Dysfunction among Middle-Aged and Older Veterans
Beaudreau, S. A., Moorleghem, K. V., Dodd, S. M., Liou‐Johnson, V., Suresh, M., & Gould, C. E. (2020) · Clinical Gerontologist · doi:10.1080/07317115.2020.1823922 · Cited by 18 · see citing works
Why is impaired sexual function distressing to men? Consequences of impaired male sexual function and their associations with sexual well-being
Stephenson, K. R., Truong, L., & Shimazu, L. (2018) · The Journal of Sexual Medicine · doi:10.1016/j.jsxm.2018.07.014 · Cited by 17 · see citing works
Results from an online survey investigating ED patients' insights and treatment expectations
Burri, A. V., & Porst, H. (2015) · International Journal of Impotence Research · doi:10.1038/ijir.2015.14 · Cited by 17 · see citing works
A Toll-Like Receptor 1/2 Agonist Augments Contractility in Rat Corpus Cavernosum
Stallmann-Jorgensen, I. S., Ogbi, S. N., Szasz, T., & Webb, R. C. (2015) · The Journal of Sexual Medicine · doi:10.1111/jsm.12960 · Cited by 17 · see citing works
The association between erectile dysfunction, depressive symptoms and testosterone levels among middle-aged men
Suija, K., Kerkelä, M., Rajala, U., Jokelainen, J. J., Laakso, M., Härkönen, P. K., Keinanen-Kiukaanniemi, S. M., & Timonen, M. (2014) · Scandinavian Journal of Public Health · doi:10.1177/1403494814545103 · Cited by 16 · see citing works
Novel noninvasive quantification of penile corpus cavernosum lesions in hyperlipidemia-induced erectile dysfunction in rabbits by two-dimensional shear-wave elastography
Li, Z., Xing, J.-F., Hu, J., Chen, H., Chen, H., Wu, Y. R., & Sun, X. (2019) · Asian Journal of Andrology · doi:10.4103/aja.aja_78_18 · Cited by 16 · see citing works
Resolution of erectile dysfunction after an andrological visit in a selected population of patients affected by psychogenic erectile dysfunction
Cavallini, G. (2015) · Asian Journal of Andrology · doi:10.4103/1008-682x.172646 · Cited by 14 · see citing works
Therapeutic management of erectile dysfunction: The AFU/SFMS guidelines
Huyghe, É., Kassab, D., Graziana, J. P., Faix, A., Grellet, L., Schoentgen, N., de Hauteclocque, A. B., Dupuis, H. G. A., Chebbi, A., Chelghaf, I., et al. (2024) · The French Journal of Urology · doi:10.1016/j.fjurol.2024.102842 · Cited by 14 · see citing works
The Sexual Function Evaluation Questionnaire (SFEQ) to Evaluate Effectiveness of Treatment for Sexual Difficulties: Development and Validation in a Clinical Sample
Mitchell, K. R., Gurney, K., McAloney‐Kocaman, K., Kiddy, C., & Parkes, A. (2021) · The Journal of Sex Research · doi:10.1080/00224499.2021.1986800 · Cited by 13 · see citing works
A Modified Procedure to Diagnose Erectile Dysfunction Using the International Index of Erectile Function (IIEF-6) Combined With the Premature Ejaculation Diagnosis Tool (PEDT) via an Internet Survey
Wang, C., Zhang, H., Liu, Z., Tu, X., & Zhang, Y. (2022) · Sexual Medicine · doi:10.1016/j.esxm.2022.100506 · Cited by 14 · see citing works
Delivery of intracavernosal therapies using needle-free injection devices
O'Kane, D. B., Gibson, L., du Plessis, J., Davidson, A., Bolton, D. M., & Lawrentschuk, N. (2017) · International Journal of Impotence Research · doi:10.1038/ijir.2017.27 · Cited by 13 · see citing works
Sildenafil’s impact on male infertility: what has changed in 20 years?
Scherzer, N., Le, T. V., & Hellstrom, W. J. G. (2019) · International Journal of Impotence Research · doi:10.1038/s41443-018-0067-x · Cited by 13 · see citing works
Early complications after penile prosthesis surgery: findings from the PHOENIX multicenter registry
van Renterghem, K., Bruyn, H. D., Yebes, Á., Calopedos, R. J. S., Dehò, F., Torremadé, J., D’Anna, M., Falagario, U. G., García‐Gómez, B., Caris, C. T. M., et al. (2025) · International Journal of Impotence Research · doi:10.1038/s41443-025-01080-z · Cited by 12 · see citing works
Association between air pollution and male sexual function: A nationwide observational study in China
Shen, Z., Zhang, F., Guo, Z., Qu, R., Wei, Y., Wang, J., Zhang, W., Xing, X., Zhang, Y., Liu, J., et al. (2024) · Journal of Hazardous Materials · doi:10.1016/j.jhazmat.2024.134010 · Cited by 12 · see citing works
Ionic Channels as Potential Therapeutic Targets for Erectile Dysfunction: A Review
Diniz, A. F. A., Ferreira, R. C., de Souza, I. L. L., & da Silva, B. A. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.01120 · Cited by 12 · see citing works
Accurately Assessing Gay Men’s Erectile Functioning: A Critique of the International Index of Erectile Function (IIEF) Use with Gay Men
Kiss, M. J., McDonagh, L., Sparks, B., Hamp, T., & Morrison, T. G. (2020) · The Journal of Sex Research · doi:10.1080/00224499.2020.1811195 · Cited by 12 · see citing works
Accurate and time‐saving, two‐step intracavernosal injection procedure to diagnose psychological erectile dysfunction
Santi, D., Spaggiari, G., Simoni, M., & Granata, A. R. M. (2022) · Andrology · doi:10.1111/andr.13175 · Cited by 11 · see citing works
The association between elevated serum oestradiol levels and clinically significant erectile dysfunction in men presenting for andrological evaluation
Zuniga, K. B., Margolin, E. J., Fazio, A. D., Ackerman, A., & Stahl, P. J. (2019) · Andrologia · doi:10.1111/and.13345 · Cited by 11 · see citing works
The management of sexual dysfunction resulting from radiotherapy and androgen deprivation therapy to treat prostate cancer: A comparison of uro‐oncology practice according to disease stage
Kinnaird, W., Kirby, M. G., Mitra, A., Davda, R., Jenkins, V. A., & Payne, H. A. (2020) · International Journal of Clinical Practice · doi:10.1111/ijcp.13873 · Cited by 9 · see citing works
An Exploration of Returning Veterans' Sexual Health Issues Using a Brief Self-Report Measure
Beaulieu, G. R., Latini, D. M., Helmer, D. A., Powers-James, C. R., Houlette, C., & Kauth, M. R. (2015) · Sexual Medicine · doi:10.1002/sm2.92 · Cited by 9 · see citing works
Development and Validation of the Sexual Contingent Self-Worth Scale
Głowacka, M. D., Rosen, N. O., Vannier, S. A., & MacLellan, M. C. (2016) · The Journal of Sex Research · doi:10.1080/00224499.2016.1186587 · Cited by 9 · see citing works
Perspectives on Sexual Health and Function of Recent Male Combat Veterans of Iraq and Afghanistan
Helmer, D. A., Beaulieu, G. R., Powers-James, C. R., Houlette, C., Latini, D. M., & Kauth, M. R. (2015) · Sexual Medicine · doi:10.1002/sm2.62 · Cited by 9 · see citing works
Predisposing factors for erectile dysfunction and response to treatment in younger males: Are they different from those of older men? An observational‐comparative study
Kızılay, F., Kalemci, S., Şimşir, A., & Altay, B. (2019) · Andrologia · doi:10.1111/and.13495 · Cited by 8 · see citing works
Comprehensive Intersystemic Assessment Approach to Relieve Psychogenic Erectile Dysfunction: A Review
Pakpahan, C., Agustinus, A., & Darmadi, D. (2021) · Open Access Macedonian Journal of Medical Sciences · doi:10.3889/oamjms.2021.6116 · Cited by 8 · see citing works
Erectile Dysfunction and Sexual Coercion: The Role of Sperm Competition Risk
Vance, G. S., Zeigler‐Hill, V., & Shackelford, T. K. (2022) · Archives of Sexual Behavior · doi:10.1007/s10508-022-02300-z · Cited by 7 · see citing works
Erectile Dysfunction: From Pathophysiology to Clinical Assessment
Mirone, V. G., Fusco, F., Cirillo, L., & Napolitano, L. (2022) · Springer eBooks · doi:10.1007/978-3-031-11701-5_3 · Cited by 7 · see citing works
Prevalence of mental health evaluation in erectile dysfunction clinical trials
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Acupuncture for erectile dysfunction: Insights and future research directions
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Authors: McCabe, M. P., & Althof, S. E.
Affiliations: Deakin University (AU)
Case Western Reserve University (US)
Corresponding author: McCabe, Marita P.
ORCID: McCabe, Marita P.
Venue: The Journal of Sexual Medicine
Publisher: Oxford University Press (OUP)
Published: 2014-02-01
Volume: 11
Issue: 2
Pages: 347-363
ISSN: 1743-6095 (ISSN-L)
1743-6109
DOI: 10.1111/jsm.12374
OpenAlex: W1948456557
Cited by: 140
References: 79
Citations by year: 2026: 11 · 2025: 13 · 2024: 11 · 2023: 11 · 2022: 12 · 2021: 8 · 2020: 15 · 2019: 12 · 2018: 11 · 2017: 11 · 2016: 12 · 2015: 8 · 2014: 4
FWCI: 1.10
Type: journal article
Language: en
Open access: closed
Licence: academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model (vor)
Locations: The Journal of Sexual Medicine (publishedVersion)
PubMed (publishedVersion)
Swinburne figshare (Swinburne University of Technology) (submittedVersion)
Topics: Health Sciences › Medicine › Psychiatry and Mental health › Sexual function and dysfunction studies
Health Sciences › Medicine › Urology › Urological Disorders and Treatments
Social Sciences › Psychology › Clinical Psychology › Sexuality, Behavior, and Technology
Keywords: erectile dysfunction, psychosocial outcomes, phosphodiesterase-5 inhibitors, sexual satisfaction, sexual relationships, self-esteem, depression, quality of life, relationship satisfaction, male sexual health
MeSH terms: Depression, Emotions, Humans, Erectile Dysfunction, Male, Middle Aged, Penile Erection, Personal Satisfaction, Sexual Behavior, Randomized Controlled Trials as Topic, Phosphodiesterase 5 Inhibitors

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A systematic review of the psychosocial outcomes associated with erectile dysfunction: does the impact of erectile dysfunction extend beyond a man's inability to have sex?

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