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Predicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research
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Objectives This review sought to identify the empirical evidence for the application of models from sociocognitive theory, self-regulation theory, and social support theory at predicting patient adherence to medications. Methods A systematic review of the published literature (1990-2010) using MEDLINE, EMBASE, Cochrane Library, CINAHL, and PsychINFO identified studies examining the application of health psychology theory to adherence to medication in adult patients. Two independent reviewers extracted data on medication, indication, study population, adherence measure, theory, model, survey instruments, and results. Heterogeneity in theoretical model specification and empirical investigation precluded a meta-analysis of data. Results Of 1756 unique records, 67 articles were included (sociocognitive = 35, self-regulation = 21, social support = 11). Adherence was most commonly measured by self-report (50 of 67). Synthesis of studies highlighted the significance (P ≤ 0.05) of self-efficacy (17 of 19), perceived barriers (11 of 17), perceived susceptibility (3 of 6), necessity beliefs (8 of 9), and medication concerns (7 of 8). Conclusions The results of this review provide a foundation for the development of theory-led adherence-enhancing interventions that could promote sustainable behavior change in clinical practice.
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From An Adaptable Framework for Factors Contributing to Medication Adherence: Results from a Systematic Review of 102 Conceptual Frameworks (2021) · cites this paper as [14]
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Metadata
- Authors
- Holmes, E. A. F., Hughes, D. A., & Morrison, V. L.
- Affiliations
- Bangor University (GB)
- Corresponding author
- Holmes, Emily A.F.
- Venue
- Value in Health
- Publisher
- Elsevier BV
- Published
- 2014-12
- Volume
- 17
- Issue
- 8
- Pages
- 863-876
- ISSN
- 1098-3015 (ISSN-L)
- OpenAlex
- W2003862222
- Cited by
- 199
- References
- 103
- Citations by year
- 2026: 6 · 2025: 11 · 2024: 7 · 2023: 16 · 2022: 22 · 2021: 17 · 2020: 31 · 2019: 52 · 2018: 19 · 2017: 9 · 2016: 8 · 2015: 1
- FWCI
- 0.78
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Value in Health (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
- Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
- Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
- Keywords
- medication adherence, health psychology theory, sociocognitive theory, self-regulation theory, social support theory, self-efficacy, perceived barriers, perceived susceptibility, necessity beliefs, medication concerns, behaviour change interventions, adult patients
- MeSH terms
- Humans, Models, Psychological, Social Support, Health Behavior, Empirical Research, Medication Adherence
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