Cited by 199Medication Adherence and CompliancePharmacy and Medical PracticesBehavioral Health and Interventions

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Predicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research

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Holmes, Emily A.F., Hughes, Dyfrig A., Morrison, Valerie L.·2014·Value in Health

DOI 10.1016/j.jval.2014.08.2671

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Abstract

Objectives This review sought to identify the empirical evidence for the application of models from sociocognitive theory, self-regulation theory, and social support theory at predicting patient adherence to medications. Methods A systematic review of the published literature (1990-2010) using MEDLINE, EMBASE, Cochrane Library, CINAHL, and PsychINFO identified studies examining the application of health psychology theory to adherence to medication in adult patients. Two independent reviewers extracted data on medication, indication, study population, adherence measure, theory, model, survey instruments, and results. Heterogeneity in theoretical model specification and empirical investigation precluded a meta-analysis of data. Results Of 1756 unique records, 67 articles were included (sociocognitive = 35, self-regulation = 21, social support = 11). Adherence was most commonly measured by self-report (50 of 67). Synthesis of studies highlighted the significance (P ≤ 0.05) of self-efficacy (17 of 19), perceived barriers (11 of 17), perceived susceptibility (3 of 6), necessity beliefs (8 of 9), and medication concerns (7 of 8). Conclusions The results of this review provide a foundation for the development of theory-led adherence-enhancing interventions that could promote sustainable behavior change in clinical practice.

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Adherence to Medical Regimens
Frain, M. P., Bishop, M. L., Tschopp, M. K., Ferrin, J. M., & Frain, J. (2009) · Rehabilitation Counseling Bulletin · doi:10.1177/0034355209333334 · Cited by 24
Promoting Compliance: The Patient-Provider Partnership
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The Use of the Theory of Planned Behavior to Predict Medication Adherence in Schizophrenia
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A Mediation Model to Explain HIV Antiretroviral Adherence Among Gay and Bisexual Men
Halkitis, P. N., & Palamar, J. J. (2007) · Sexual and Gender Diversity in Social Services · doi:10.1300/j041v19n01_03 · Cited by 6

Flagged first, then by citations

1 of the 103 references couldn’t be matched to a known paper.

Research works printed but not linked: 3

Nasseh, 2012, Cost of medication nonadherence associated with diabetes, hypertension, and dyslipidemia, Am J Pharm Benefits, 4, e41
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Sorted by citations

Is patient empowerment the key to promote adherence? A systematic review of the relationship between self-efficacy, health locus of control and medication adherence
Náfrádi, L., Nakamoto, K., & Schulz, P. J. (2017) · PLoS ONE · doi:10.1371/journal.pone.0186458 · Cited by 555
Supporting Adherence to Medicines for Long-Term Conditions
Horne, R., Cooper, V., Wileman, V., & Chan, A. H. Y. (2019) · European Psychologist · doi:10.1027/1016-9040/a000353 · Cited by 178
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An Adaptable Framework for Factors Contributing to Medication Adherence: Results from a Systematic Review of 102 Conceptual Frameworks
Peh, K. Q. E., Kwan, Y. H., Goh, H., Ramchandani, H., Phang, J. K., Lim, Z. Y., Loh, D. H. F., Østbye, T., Blalock, D. V., Yoon, S., et al. (2021) · Journal of General Internal Medicine · doi:10.1007/s11606-021-06648-1 · Cited by 151
Theory-Based Interventions to Improve Medication Adherence in Older Adults Prescribed Polypharmacy: A Systematic Review
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See all 199

Authors: Holmes, E. A. F., Hughes, D. A., & Morrison, V. L.
Affiliations: Bangor University (GB)
Corresponding author: Holmes, Emily A.F.
ORCID: Holmes, Emily A.F.
Hughes, Dyfrig A.
Venue: Value in Health
Publisher: Elsevier BV
Published: 2014-12
Volume: 17
Issue: 8
Pages: 863-876
ISSN: 1098-3015 (ISSN-L)
DOI: 10.1016/j.jval.2014.08.2671
OpenAlex: W2003862222
Cited by: 199
References: 103
Citations by year: 2026: 6 · 2025: 11 · 2024: 7 · 2023: 16 · 2022: 22 · 2021: 17 · 2020: 31 · 2019: 52 · 2018: 19 · 2017: 9 · 2016: 8 · 2015: 1
FWCI: 0.78
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 365 d)
Locations: Value in Health (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Family Practice › Medication Adherence and Compliance
Health Sciences › Health Professions › Pharmacy › Pharmacy and Medical Practices
Social Sciences › Psychology › Applied Psychology › Behavioral Health and Interventions
Keywords: medication adherence, health psychology theory, sociocognitive theory, self-regulation theory, social support theory, self-efficacy, perceived barriers, perceived susceptibility, necessity beliefs, medication concerns, behaviour change interventions, adult patients
MeSH terms: Humans, Models, Psychological, Social Support, Health Behavior, Empirical Research, Medication Adherence

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Predicting Adherence to Medications Using Health Psychology Theories: A Systematic Review of 20 Years of Empirical Research

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