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Cited by 727

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Structure–radical scavenging activity relationships of phenolic compounds from traditional Chinese medicinal plants

Cai, Yi-Zhong, Mei Sun, Jie Xing, Luo, Qiong, Corke, Harold·2006·Life Sciences
DOI 10.1016/j.lfs.2005.11.004
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Abstract

Traditional Chinese medicinal plants associated with anticancer contain a wide variety of natural phenolic compounds with various structural features and possessing widely differing antioxidant activity. The structure-radical scavenging activity relationships of a large number of representative phenolic compounds (e.g., flavanols, flavonols, chalcones, flavones, flavanones, isoflavones, tannins, stilbenes, curcuminoids, phenolic acids, coumarins, lignans, and quinones) identified in the traditional Chinese medicinal plants were evaluated using the improved ABTS*+ and DPPH methods. Different categories of tested phenolics showed significant mean differences in radical scavenging activity. Tannins demonstrated the strongest activity, while most quinones, isoflavones, and lignans tested showed the weakest activity. This study confirmed that the number and position of hydroxyl groups and the related glycosylation and other substitutions largely determined radical scavenging activity of the tested phenolic compounds. The differences in radical scavenging activity were attributed to structural differences in hydroxylation, glycosylation and methoxylation. The ortho-dihydroxy groups were the most important structural feature of high activity for all tested phenolic compounds. Other structural features played a modified role in enhancing or reducing the activity. Within each class of phenolic compounds, the structure-activity relationship was elucidated and discussed. This study reve…

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Metadata

Authors
Cai, Y.-Z., Sun, M., Xing, J., Luo, Q., & Corke, H.
Venue
Life Sciences
Publisher
Elsevier BV
Published
2006-05
Volume
78
Issue
25
Pages
2872-2888
ISSN
0024-3205
DOI
10.1016/j.lfs.2005.11.004
Cited by
727
References
1
Language
en
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)

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CoChat. (2026). Citation check: Structure–radical scavenging activity relationships of phenolic compounds from traditional Chinese medicinal plants. https://app.cochat.ai/papers/10.1016/j.lfs.2005.11.004
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Cai, Y.-Z., Sun, M., Xing, J., Luo, Q., & Corke, H. (2006). Structure–radical scavenging activity relationships of phenolic compounds from traditional Chinese medicinal plants. Life Sciences. https://doi.org/10.1016/j.lfs.2005.11.004

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