Mitochondria-associated membrane-modulated Ca2+ transfer: A potential treatment target in cardiac ischemia reperfusion injury and heart failure

Myocardial Reperfusion Injury

Yellon, D. M., & Hausenloy, D. J. (2007) · New England Journal of Medicine · doi:10.1056/nejmra071667 · Cited by 3,797 · see citing works

Fission and selective fusion govern mitochondrial segregation and elimination by autophagy

Twig, G., Elorza, A., Molina, A. J. A., Mohamed, H., Wikstrom, J. D., Walzer, G., Stiles, L., Haigh, S. E., Katz, S., Las, G., et al. (2008) · The EMBO Journal · doi:10.1038/sj.emboj.7601963 · Cited by 3,082 · see citing works

Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1.

Urano, F., Wang, X.-Z., Bertolotti, A., Zhang, Y.-H., Chung, P., Harding, H., & Ron, D. (2000) · Science · doi:10.1126/science.287.5453.664 · Cited by 3,081 · see citing works

Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development

Chen, H., Detmer, S. A., Ewald, A. J., Griffin, E. E., Fraser, S. E., & Chan, D. C. (2003) · The Journal of Cell Biology · doi:10.1083/jcb.200211046 · Cited by 2,601 · see citing works

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

de Brito, O. M., & Scorrano, L. (2008) · Nature · doi:10.1038/nature07534 · Cited by 2,442 · see citing works

Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death

Baines, C. P., Kaiser, R. A., Purcell, N. H., Blair, N. S., Osinska, H., Hambleton, M. A., Brunskill, E. W., Sayen, M. R., Gottlieb, R. A., Dorn, G. W., et al. (2005) · Nature · doi:10.1038/nature03434 · Cited by 2,280 · see citing works

Close Contacts with the Endoplasmic Reticulum as Determinants of Mitochondrial Ca ²⁺ Responses

Rizzuto, R., Pinton, P., Carrington, W., Fay, F. S., Fogarty, K. E., Lifshitz, L. M., Tuft, R. A., & Pozzan, T. (1998) · Science · doi:10.1126/science.280.5370.1763 · Cited by 2,257 · see citing works

ER Tubules Mark Sites of Mitochondrial Division

Friedman, J. R., Lackner, L. L., West, M., DiBenedetto, J. R., Nunnari, J., & Voeltz, G. K. (2011) · Science · doi:10.1126/science.1207385 · Cited by 2,072 · see citing works

Integrative genomics identifies MCU as an essential component of the mitochondrial calcium uniporter

Baughman, J. M., Perocchi, F., Girgis, H. S., Plovanich, M. E., Belcher-Timme, C. A., Sancak, Y., Bao, X., Strittmatter, L., Goldberger, O., Bogorad, R., et al. (2011) · Nature · doi:10.1038/nature10234 · Cited by 1,926 · see citing works

Regulation of cardiac hypertrophy by intracellular signalling pathways

Heineke, J., & Molkentin, J. D. (2006) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm1983 · Cited by 1,856 · see citing works

Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival

Hayashi, T., & Su, T.-P. (2007) · Cell · doi:10.1016/j.cell.2007.08.036 · Cited by 1,826 · see citing works

Autophagosomes form at ER–mitochondria contact sites

Hamasaki, M., Furuta, N., Matsuda, A., Nezu, A., Yamamoto, A., Fujita, N., Oomori, H., Noda, T., Haraguchi, T., Hiraoka, Y., et al. (2013) · Nature · doi:10.1038/nature11910 · Cited by 1,747 · see citing works

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

Liu, L., Feng, D., Chen, G., Chen, M., Zheng, Q., Song, P., Ma, Q., Zhu, C., Wang, R., Qi, W., et al. (2012) · Nature Cell Biology · doi:10.1038/ncb2422 · Cited by 1,689 · see citing works

Cyclophilin D-dependent mitochondrial permeability transition regulates some necrotic but not apoptotic cell death

Nakagawa, T., Shimizu, S., Watanabe, T., Yamaguchi, O., Otsu, K., Yamagata, H., Inohara, H., Kubo, T., & Tsujimoto, Y. (2005) · Nature · doi:10.1038/nature03317 · Cited by 1,635 · see citing works

The Unfolded Protein Response and Cell Fate Control

Hetz, C. A., & Papa, F. R. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.06.017 · Cited by 1,567 · see citing works

Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion: Roles of AMP-Activated Protein Kinase and Beclin 1 in Mediating Autophagy

Matsui, Y., Takagi, H., Qu, X., Abdellatif, M., Sakoda, H., Asano, T., Levine, B., & Sadoshima, J. (2007) · Circulation Research · doi:10.1161/01.res.0000261924.76669.36 · Cited by 1,505 · see citing works

A forty-kilodalton protein of the inner membrane is the mitochondrial calcium uniporter

Stefani, D. D., Raffaello, A., Teardo, E., Szabò, I., & Rizzuto, R. (2011) · Nature · doi:10.1038/nature10230 · Cited by 1,431 · see citing works

Mitochondria Supply Membranes for Autophagosome Biogenesis during Starvation

Hailey, D. W., Rambold, A. S., Satpute‐Krishnan, P., Mitra, K., Sougrat, R., Kim, P. K., & Lippincott‐Schwartz, J. (2010) · Cell · doi:10.1016/j.cell.2010.04.009 · Cited by 1,419 · see citing works

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2+ channels

Szabadkai, G., Bianchi, K., Várnai, P., De Stefani, D., Wieckowski, M. R., Cavagna, D., Nagy, A. I., Balla, T., & Rizzuto, R. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200608073 · Cited by 1,413 · see citing works

2009 Focused Update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults

Jessup, M. L., Abraham, W. T., Casey, D. E., Feldman, A. M., Francis, G. S., Ganiats, T. G., Konstam, M. A., MANCINI, D. M., Rahko, P. S., Silver, M. A., et al. (2009) · Circulation · doi:10.1161/circulationaha.109.192064 · Cited by 1,404 · see citing works

BAX and BAK Regulation of Endoplasmic Reticulum Ca 2+ : A Control Point for Apoptosis

Scorrano, L., Oakes, S. A., Opferman, J. T., Cheng, E. H. Y., Sorcinelli, M. D., Pozzan, T., & Korsmeyer, S. J. (2003) · Science · doi:10.1126/science.1081208 · Cited by 1,387 · see citing works

Structural and functional features and significance of the physical linkage between ER and mitochondria

Csordás, G., Renken, C. W., Várnai, P., Walter, L., Weaver, D., BUTTLE, K. F., Balla, T., Mannella, C. A., & Hajnóczky, G. (2006) · The Journal of Cell Biology · doi:10.1083/jcb.200604016 · Cited by 1,377 · see citing works

Myocardial reperfusion: a double-edged sword?

D, E. B. M., & Kloner, R. A. (1985) · Journal of Clinical Investigation · doi:10.1172/jci112160 · Cited by 1,368 · see citing works

An ER-Mitochondria Tethering Complex Revealed by a Synthetic Biology Screen

Kornmann, B., Currie, E., Collins, S. R., Schuldiner, M., Nunnari, J., Weissman, J. S., & Walter, P. (2009) · Science · doi:10.1126/science.1175088 · Cited by 1,275 · see citing works

Phospholipid synthesis in a membrane fraction associated with mitochondria.

Vance, J. E. (1990) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)39106-9 · Cited by 1,153 · see citing works

Mitochondrial dynamics and inheritance during cell division, development and disease

Mishra, P., & Chan, D. C. (2014) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm3877 · Cited by 1,038 · see citing works

Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

Juhaszova, M., Zorov, D. B., Kim, S.-H., Pepe, S., Fu, Q., Fishbein, K. W., Ziman, B. D., Wang, S., Kirsti Ytrehus, B., Antos, C. L., et al. (2004) · Journal of Clinical Investigation · doi:10.1172/jci19906 · Cited by 1,029 · see citing works

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

Ong, S.-B., Subrayan, S., Lim, S. Y., Yellon, D. M., Davidson, S. M., & Hausenloy, D. J. (2010) · Circulation · doi:10.1161/circulationaha.109.906610 · Cited by 986 · see citing works

The Fas Signaling Pathway: More Than a Paradigm

Wajant, H. (2002) · Science · doi:10.1126/science.1071553 · Cited by 957 · see citing works

Molecular mechanisms of ROS production and oxidative stress in diabetes

Newsholme, P., Cruzat, V. F., Keane, K. N., Carlessi, R., & de Bittencourt, P. I. H. (2016) · Biochemical Journal · doi:10.1042/bcj20160503c · Cited by 878 · see citing works

PERK is required at the ER-mitochondrial contact sites to convey apoptosis after ROS-based ER stress

Verfaillie, T., Rubio, N., Garg, A. D., Bultynck, G., Rizzuto, R., Decuypere, J.-P., Piette, J. G., Linehan, C., Gupta, S., Afshin Samali, A., et al. (2012) · Cell Death and Differentiation · doi:10.1038/cdd.2012.74 · Cited by 851 · see citing works

IRE1α Induces Thioredoxin-Interacting Protein to Activate the NLRP3 Inflammasome and Promote Programmed Cell Death under Irremediable ER Stress

Lerner, A. G., Upton, J.-P., Praveen, P. V. K., Ghosh, R., Nakagawa, Y., Igbaria, A., Shen, S., Nguyen, V. Q., Backes, B. J., Heiman, M., et al. (2012) · Cell Metabolism · doi:10.1016/j.cmet.2012.07.007 · Cited by 841 · see citing works

An Actin-Dependent Step in Mitochondrial Fission Mediated by the ER-Associated Formin INF2

Korobova, F., Ramabhadran, V., & Higgs, H. N. (2013) · Science · doi:10.1126/science.1228360 · Cited by 817 · see citing works

Mitochondrial function as a therapeutic target in heart failure

Brown, D. A., Perry, J. B., Allen, M. E., Sabbah, H. N., Stauffer, B. L., Shaikh, S. R., Cleland, J. G. F., Colucci, W. S., Butler, J., Voors, A. A., et al. (2016) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2016.203 · Cited by 811 · see citing works

Relation between myocardial function and expression of sarcoplasmic reticulum Ca(2+)-ATPase in failing and nonfailing human myocardium.

Hasenfuss, G. P., Reinecke, H., Studer, R., Meyer, M., Pieske, B. M., Holtz, J., Holubarsch, C., Posival, H., Just, H., & Drexler, H. (1994) · Circulation Research · doi:10.1161/01.res.75.3.434 · Cited by 781 · see citing works

Imaging interorganelle contacts and local calcium dynamics at the ER-mitochondrial interface

Csordás, G., Várnai, P., Golenár, T., Roy, S., Purkins, G., Schneider, T. G., Balla, T., & Hajnóczky, G. (2010) · Molecular Cell · doi:10.1016/j.molcel.2010.06.029 · Cited by 750 · see citing works

Mitochondrial calcium transport: physiological and pathological relevance

Gunter, T. E., Gunter, K. K., Sheu, S. S., & Gavin, C. E. (1994) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.1994.267.2.c313 · Cited by 698 · see citing works

Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death

Marchi, S., Patergnani, S., Missiroli, S., Morciano, G., Rimessi, A., Wieckowski, M. R., Giorgi, C., & Pinton, P. (2017) · Cell Calcium · doi:10.1016/j.ceca.2017.05.003 · Cited by 695 · see citing works

ER-mitochondria contacts couple mtDNA synthesis with mitochondrial division in human cells

Lewis, S. C., Uchiyama, L. F., & Nunnari, J. (2016) · Science · doi:10.1126/science.aaf5549 · Cited by 673 · see citing works

MICU1 Is an Essential Gatekeeper for MCU-Mediated Mitochondrial Ca2+ Uptake that Regulates Cell Survival

Mallilankaraman, K. B., Doonan, P. J., Cárdenas, C., Chandramoorthy, H. C. K., Müller, M., Miller, R., Hoffman, N. E., Gandhirajan, R. K., Molgó, J., Birnbaum, M. J., et al. (2012) · Cell · doi:10.1016/j.cell.2012.10.011 · Cited by 661 · see citing works

Increased ER–mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

Bravo, R., Vicencio, J. M., Parra, V., Troncoso, R., Muñoz, J. P., Bui, M., Quiroga, C., Rodriguez, A. E., Verdejo, H., Ferreira, J., et al. (2011) · Journal of Cell Science · doi:10.1242/jcs.080762 · Cited by 607 · see citing works

ULK1 translocates to mitochondria and phosphorylates FUNDC1 to regulate mitophagy

Wu, W., Tian, W., Hu, Z., Chen, G., Huang, L. H., Li, W., Zhang, X., Xue, P., Zhou, C., Liu, L., et al. (2014) · EMBO Reports · doi:10.1002/embr.201438501 · Cited by 586 · see citing works

The origin of the autophagosomal membrane

Tooze, S. A., & Yoshimori, T. (2010) · Nature Cell Biology · doi:10.1038/ncb0910-831 · Cited by 585 · see citing works

Mitofusin 2 ablation increases endoplasmic reticulum–mitochondria coupling

Filadi, R., Greotti, E., Turacchio, G., Luini, A., Pozzan, T., & Pizzo, P. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1504880112 · Cited by 578 · see citing works

Mitochondrial calcium overload is a key determinant in heart failure

Santulli, G., Xie, W., Reiken, S. R., & Marks, A. R. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1513047112 · Cited by 561 · see citing works

The Role of Autophagy in the Heart

Sciarretta, S., Maejima, Y., Zablocki, D., & Sadoshima, J. (2018) · Annual Review of Physiology · doi:10.1146/annurev-physiol-021317-121427 · Cited by 547 · see citing works

Mitochondrial Control of Cellular Life, Stress, and Death

Galluzzi, L., Kepp, O., Trojel‐Hansen, C., & Kroemer, G. (2012) · Circulation Research · doi:10.1161/circresaha.112.268946 · Cited by 545 · see citing works

Fis1 and Bap31 bridge the mitochondria–ER interface to establish a platform for apoptosis induction

Iwasawa, R., Mahul‐Mellier, A., Datler, C., Pazarentzos, E., & Grimm, S. (2011) · The EMBO Journal · doi:10.1038/emboj.2010.346 · Cited by 520 · see citing works

Mitochondrial Fusion is Essential for Organelle Function and Cardiac Homeostasis

Chen, Y., Liu, Y., & Dorn, G. W. (2011) · Circulation Research · doi:10.1161/circresaha.111.258723 · Cited by 506 · see citing works

Cyclophilin‐D binds strongly to complexes of the voltage‐dependent anion channel and the adenine nucleotide translocase to form the permeability transition pore

Crompton, M., Virji, S., & Ward, J. M. (1998) · European Journal of Biochemistry · doi:10.1046/j.1432-1327.1998.2580729.x · Cited by 492 · see citing works

Mitochondrial Fission and Fusion Factors Reciprocally Orchestrate Mitophagic Culling in Mouse Hearts and Cultured Fibroblasts

Song, M., Mihara, K., Chen, Y., Scorrano, L., & Dorn, G. W. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2014.12.011 · Cited by 482 · see citing works

Parkin Protein Deficiency Exacerbates Cardiac Injury and Reduces Survival following Myocardial Infarction

Kubli, D. A., Zhang, X., Lee, Y., Hanna, R. A., Quinsay, M. N., Nguyen, C. K., Jimenez, R., Petrosyan, S., Murphy, A. N., & Gustafsson, Å. B. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.411363 · Cited by 476 · see citing works

A unique mitochondria-associated membrane fraction from rat liver has a high capacity for lipid synthesis and contains pre-Golgi secretory proteins including nascent lipoproteins.

Rusiñol, A. E., Cui, Z., Chen, M. H., & Vance, J. E. (1994) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)47012-3 · Cited by 469 · see citing works

Physiological and Pathological Roles of the Mitochondrial Permeability Transition Pore in the Heart

Kwong, J. Q., & Molkentin, J. D. (2015) · Cell Metabolism · doi:10.1016/j.cmet.2014.12.001 · Cited by 463 · see citing works

Mfn2 modulates the UPR and mitochondrial function via repression of PERK

Muñoz, J. P., Ivanova, S., Sánchez‐Wandelmer, J., Martínez‐Cristóbal, P., Noguera, E., Sancho, A., Díaz‐Ramos, A., Hernández‐Alvarez, M. I., Sebastián, D., Mauvezin, C., et al. (2013) · The EMBO Journal · doi:10.1038/emboj.2013.168 · Cited by 451 · see citing works

Type I, II, and III Inositol 1,4,5-Trisphosphate Receptors Are Unequally Susceptible to Down-regulation and Are Expressed in Markedly Different Proportions in Different Cell Types

Wojcikiewicz, R. J. H. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.19.11678 · Cited by 414 · see citing works

The ER-Mitochondria Tethering Complex VAPB-PTPIP51 Regulates Autophagy

Gómez‐Suaga, P., Paillusson, S., Stoica, R., Noble, W. J., Hanger, D. P., & Miller, C. C. J. (2017) · Current Biology · doi:10.1016/j.cub.2016.12.038 · Cited by 413 · see citing works

Calcium cycling proteins and heart failure: mechanisms and therapeutics

Marks, A. R. (2013) · Journal of Clinical Investigation · doi:10.1172/jci62834 · Cited by 403 · see citing works

The endoplasmic reticulum enzyme DGAT2 is found in mitochondria-associated membranes and has a mitochondrial targeting signal that promotes its association with mitochondria

Stone, S. J., Levin, M. C., Zhou, P., Han, J., Walther, T. C., & Farese, R. V. (2009) · Journal of Biological Chemistry · doi:10.1074/jbc.m805768200 · Cited by 390 · see citing works

Cyclophilin D controls mitochondrial pore–dependent Ca2+ exchange, metabolic flexibility, and propensity for heart failure in mice

Elrod, J. W., Wong, R., Mishra, S., Vagnozzi, R. J., Sakthievel, B., Goonasekera, S. A., Karch, J., Gabel, S., Farber, J., Force, T., et al. (2010) · Journal of Clinical Investigation · doi:10.1172/jci43171 · Cited by 384 · see citing works

Phosphorylation of Glycogen Synthase Kinase-3β During Preconditioning Through a Phosphatidylinositol-3-Kinase–Dependent Pathway Is Cardioprotective

Tong, H., Imahashi, K., Steenbergen, C., & Murphy, E. (2002) · Circulation Research · doi:10.1161/01.res.0000012567.95445.55 · Cited by 377 · see citing works

Cardiac mitochondria in heart failure: decrease in respirasomes and oxidative phosphorylation

Rosca, M. G., Vazquez, E. J., Kerner, J., Parland, W., Chandler, M. P., Stanley, W. C., Sabbah, H. N., & Hoppel, C. L. (2008) · Cardiovascular Research · doi:10.1093/cvr/cvn184 · Cited by 373 · see citing works

Elevated Cytosolic Na + Decreases Mitochondrial Ca 2+ Uptake During Excitation-Contraction Coupling and Impairs Energetic Adaptation in Cardiac Myocytes

Maack, C., Cortassa, S. C., Aon, M. A., Ganesan, A. N., Liu, T., & O'Rourke, B. P. (2006) · Circulation Research · doi:10.1161/01.res.0000232546.92777.05 · Cited by 369 · see citing works

α-Synuclein binds to the ER–mitochondria tethering protein VAPB to disrupt Ca2+ homeostasis and mitochondrial ATP production

Paillusson, S., Gómez‐Suaga, P., Stoica, R., Little, D., Gissen, P., Devine, M. J., Noble, W. J., Hanger, D. P., & Miller, C. C. J. (2017) · Acta Neuropathologica · doi:10.1007/s00401-017-1704-z · Cited by 369 · see citing works

Mitofusin-2 Maintains Mitochondrial Structure and Contributes to Stress-Induced Permeability Transition in Cardiac Myocytes

Papanicolaou, K. N., Khairallah, R. J., Ngoh, G. A., Chikando, A. C., Luptak, I., O’Shea, K. M., Riley, D. D., Lugus, J. J., Colucci, W. S., Lederer, W. J., et al. (2011) · Molecular and Cellular Biology · doi:10.1128/mcb.00911-10 · Cited by 358 · see citing works

PINK1 and BECN1 relocalize at mitochondria-associated membranes during mitophagy and promote ER-mitochondria tethering and autophagosome formation

Gelmetti, V., Rosa, P. D., Torosantucci, L., Marini, E. S., Romagnoli, A., Rienzo, M. D., Arena, G., Vignone, D., Fimia, G. M., & Valente, E. M. (2017) · Autophagy · doi:10.1080/15548627.2016.1277309 · Cited by 355 · see citing works

Dynamin‐related protein 1 (Drp1)‐mediated diastolic dysfunction in myocardial ischemia‐reperfusion injury: therapeutic benefits of Drp1 inhibition to reduce mitochondrial fission

Sharp, W. W., Fang, Y.-H., Han, M., Zhang, H. J., Hong, Z.-G., Banathy, A., Morrow, E., Ryan, J., & Archer, S. (2014) · The FASEB Journal · doi:10.1096/fj.12-226225 · Cited by 353 · see citing works

INF2-mediated actin polymerization at the ER stimulates mitochondrial calcium uptake, inner membrane constriction, and division

Chakrabarti, R., Ji, W.-K., Stan, R. V., de Juan Sanz, J., Ryan, T. A., & Higgs, H. N. (2018) · Journal of Cell Biology · doi:10.1083/jcb.201709111 · Cited by 349 · see citing works

Mitofusin 2-Containing Mitochondrial-Reticular Microdomains Direct Rapid Cardiomyocyte Bioenergetic Responses Via Interorganelle Ca 2+ Crosstalk

Chen, Y., Csordás, G., Jowdy, C. C., Schneider, T. G., Csordás, N., Wang, W., Liu, Y., Kohlhaas, M., Meiser, M., Bergem, S., et al. (2012) · Circulation Research · doi:10.1161/circresaha.112.266585 · Cited by 348 · see citing works

Preconditioning Involves Selective Mitophagy Mediated by Parkin and p62/SQSTM1

Huang, C., Andres, A. M., Ratliff, E. P., Hernandez, G., Lee, P. P. W., & Gottlieb, R. A. (2011) · PLoS ONE · doi:10.1371/journal.pone.0020975 · Cited by 344 · see citing works

Mitochondria as a Therapeutic Target in Heart Failure

Bayeva, M., Gheorghiade, M., & Ardehali, H. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.08.1021 · Cited by 336 · see citing works

The mitochondrial permeability transition pore: a mystery solved?

Bernardi, P. (2013) · Frontiers in Physiology · doi:10.3389/fphys.2013.00095 · Cited by 335 · see citing works

Inhibition of GSK3β by Postconditioning Is Required to Prevent Opening of the Mitochondrial Permeability Transition Pore During Reperfusion

Gomez, L., Paillard, M., Thibault, H., Dérumeaux, G., & Ovize, M. (2008) · Circulation · doi:10.1161/circulationaha.107.755066 · Cited by 335 · see citing works

The Conserved GTPase Gem1 Regulates Endoplasmic Reticulum–Mitochondria Connections

Kornmann, B., Osman, C., & Walter, P. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1111314108 · Cited by 335 · see citing works

Mitochondria-Associated Membranes: Composition, Molecular Mechanisms, and Physiopathological Implications

Giorgi, C., Missiroli, S., Patergnani, S., Duszyński, J., Wieckowski, M. R., & Pinton, P. (2015) · Antioxidants and Redox Signaling · doi:10.1089/ars.2014.6223 · Cited by 332 · see citing works

The AMPK-MFN2 axis regulates MAM dynamics and autophagy induced by energy stresses

Hu, Y., Chen, H., Zhang, L., Lin, X., Li, X., Zhuang, H., Fan, H., Meng, T., He, Z., Huang, H., et al. (2020) · Autophagy · doi:10.1080/15548627.2020.1749490 · Cited by 331 · see citing works

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition

Bonora, M., Wieckowski, M. R., Chinopoulos, C., Kepp, O., Kroemer, G., Galluzzi, L., & Pinton, P. (2015) · Oncogene · doi:10.1038/onc.2014.96 · Cited by 330 · see citing works

ATF6 Decreases Myocardial Ischemia/Reperfusion Damage and Links ER Stress and Oxidative Stress Signaling Pathways in the Heart

Jin, J.-K., Blackwood, E. A., Azizi, K., Thuerauf, D. J., Fahem, A. G., Hofmann, C. P., Kaufman, R. J., Doroudgar, S., & Glembotski, C. C. (2016) · Circulation Research · doi:10.1161/circresaha.116.310266 · Cited by 330 · see citing works

Molecular Mechanisms of Mitochondrial Autophagy/Mitophagy in the Heart

Saito, T., & Sadoshima, J. (2015) · Circulation Research · doi:10.1161/circresaha.116.303790 · Cited by 321 · see citing works

Binding of FUN14 domain containing 1 with inositol 1,4,5-trisphosphate receptor in mitochondria-associated endoplasmic reticulum membranes maintains mitochondrial dynamics and function in hearts in vivo

Wu, S., Lu, Q., Wang, Q., Ding, Y., Ma, Z., Mao, X., Huang, K., Xie, Z., & Zou, M.-H. (2017) · Circulation · doi:10.1161/circulationaha.117.030235 · Cited by 320 · see citing works

Calcium-mediated cell death during myocardial reperfusion

García‐Dorado, D., Ruiz‐Meana, M., Inserte, J., Rodríguez‐Sinovas, A., & Piper, H. M. (2012) · Cardiovascular Research · doi:10.1093/cvr/cvs116 · Cited by 308 · see citing works

The Voltage-Dependent Anion Channel (VDAC): Function in Intracellular Signalling, Cell Life and Cell Death

Shoshan‐Barmatz, V., Israelson, A., Brdiczka, D. G., & Sheu, S. (2006) · Current Pharmaceutical Design · doi:10.2174/138161206777585111 · Cited by 307 · see citing works

DJ-1 regulates the integrity and function of ER-mitochondria association through interaction with IP3R3-Grp75-VDAC1

Liu, Y., Ma, X., Fujioka, H., Liu, J., Chen, S., & Zhu, X. (2019) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1906565116 · Cited by 299 · see citing works

Hyperglycemia-Driven Inhibition of AMP-Activated Protein Kinase α2 Induces Diabetic Cardiomyopathy by Promoting Mitochondria-Associated Endoplasmic Reticulum Membranes In Vivo

Wu, S., Lu, Q., Ding, Y., Wu, Y., Qiu, Y., Wang, P., Mao, X., Huang, K., Xie, Z., & Zou, M.-H. (2019) · Circulation · doi:10.1161/circulationaha.118.033552 · Cited by 298 · see citing works

The UPRER: Sensor and Coordinator of Organismal Homeostasis.

Frakes, A. E., & Dillin, A. (2017) · Molecules and Cells · doi:10.1016/j.molcel.2017.05.031 · Cited by 295 · see citing works

Non-canonical function of IRE1α determines mitochondria-associated endoplasmic reticulum composition to control calcium transfer and bioenergetics

Carreras‐Sureda, A., Jaña, F., Urra, H., Durand, S., Mortenson, D. E., Sagredo, A. I., Bustos, G., Hazari, Y., Ramos‐Fernández, E., Sassano, M. L., et al. (2019) · Nature Cell Biology · doi:10.1038/s41556-019-0329-y · Cited by 286 · see citing works

Depressing Mitochondria-Reticulum Interactions Protects Cardiomyocytes From Lethal Hypoxia-Reoxygenation Injury

Paillard, M., Tubbs, E., Thiébaut, P., Gomez, L., Fauconnier, J., Silva, C. C. D., Teixeira, G., Mewton, N., Belaïdi, E., Durand, A., et al. (2013) · Circulation · doi:10.1161/circulationaha.113.001225 · Cited by 279 · see citing works

Lipid composition of mitochondria from bovine heart, liver, and kidney

Fleischer, S., Rouser, G., Fleischer, B., Casu, A., & Kritchevsky, G. (1967) · Journal of Lipid Research · doi:10.1016/s0022-2275(20)40133-6 · Cited by 270 · see citing works

Preconditioning and postconditioning: The essential role of the mitochondrial permeability transition pore

Lim, S. Y., Davidson, S. M., Hausenloy, D. J., & Yellon, D. M. (2007) · Cardiovascular Research · doi:10.1016/j.cardiores.2007.04.022 · Cited by 270 · see citing works

Mitochondria as a Drug Target in Ischemic Heart Disease and Cardiomyopathy

Walters, A. M., Porter, G. A., Jr., & Brookes, P. S. (2012) · Circulation Research · doi:10.1161/circresaha.112.265660 · Cited by 268 · see citing works

Physiologic Functions of Cyclophilin D and the Mitochondrial Permeability Transition Pore

Elrod, J. W., & Molkentin, J. D. (2013) · Circulation Journal · doi:10.1253/circj.cj-13-0321 · Cited by 266 · see citing works

Increased Drp1 Acetylation by Lipid Overload Induces Cardiomyocyte Death and Heart Dysfunction

Hu, Q., Zhang, H., Cortés, N. G., Wu, D., Wang, P., Zhang, J., Mattison, J. A., Smith, E., Bettcher, L., Wang, M., et al. (2020) · Circulation Research · doi:10.1161/circresaha.119.315252 · Cited by 261 · see citing works

ALS/FTD‐associated FUS activates GSK‐3β to disrupt the VAPB–PTPIP51 interaction and ER–mitochondria associations

Stoica, R., Paillusson, S., Gómez‐Suaga, P., Mitchell, J. C., Lau, D. H. W., Gray, E. H., Sancho, R. M., Vizcay‐Barrena, G., Vos, K. J. D., Shaw, C. E., et al. (2016) · EMBO Reports · doi:10.15252/embr.201541726 · Cited by 254 · see citing works

Differential regulation of two types of intracellular calcium release channels during end-stage heart failure.

Go, L. O., Moschella, M. C., Watras, J. M., Handa, K. K., Fyfe, B. S., & Marks, A. R. (1995) · Journal of Clinical Investigation · doi:10.1172/jci117739 · Cited by 247 · see citing works

Modulation of the mitochondrial permeability transition pore complex in GSK-3β-mediated myocardial protection

Nishihara, M., Miura, T., Miki, T., Tanno, M., Yano, T., Naitoh, K., Ohori, K., Hotta, H., Terashima, Y., & Shimamoto, K. (2007) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2007.08.010 · Cited by 235 · see citing works

Mitochondrial Ca2+ Uniporter Is a Mitochondrial Luminal Redox Sensor that Augments MCU Channel Activity

Dong, Z., Shanmughapriya, S., Tomar, D., Siddiqui, N., Lynch, S., Nemani, N., Breves, S. L., Zhang, X., Tripathi, A., Palaniappan, P., et al. (2017) · Molecular Cell · doi:10.1016/j.molcel.2017.01.032 · Cited by 233 · see citing works

Protective role of melatonin in cardiac ischemia‐reperfusion injury: From pathogenesis to targeted therapy

Zhou, H., Ma, Q., Zhu, P., Ren, J. T., Reiter, R. J., & Chen, Y. (2018) · Journal of Pineal Research · doi:10.1111/jpi.12471 · Cited by 228 · see citing works

Mitofusin-2 Independent Juxtaposition of Endoplasmic Reticulum and Mitochondria: An Ultrastructural Study

Cosson, P., Marchetti, A., Ravazzola, M., & Orci, L. (2012) · PLoS ONE · doi:10.1371/journal.pone.0046293 · Cited by 226 · see citing works

Interactions between sarco-endoplasmic reticulum and mitochondria in cardiac and skeletal muscle – pivotal roles in Ca2+ and reactive oxygen species signaling

Eisner, V., Csordás, G., & Hajnóczky, G. (2013) · Journal of Cell Science · doi:10.1242/jcs.093609 · Cited by 215 · see citing works

2009 Focused Update: ACCF/AHA Guidelines for the Diagnosis and Management of Heart Failure in Adults

Jessup, M. L., Abraham, W. T., Casey, D. E., Feldman, A. M., Francis, G. S., Ganiats, T. G., Konstam, M. A., MANCINI, D. M., Rahko, P. S., Silver, M. A., et al. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.11.009 · Cited by 214 · see citing works

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging

Santulli, G., & Marks, A. R. (2015) · Current Molecular Pharmacology · doi:10.2174/1874467208666150507105105 · Cited by 212 · see citing works

MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics

Tomar, D., Dong, Z., Shanmughapriya, S., Koch, D. A., Thomas, T. P., Hoffman, N. E., Timbalia, S. A., Goldman, S. J., Breves, S. L., Corbally, D. P., et al. (2016) · Cell Reports · doi:10.1016/j.celrep.2016.04.050 · Cited by 210 · see citing works

Central Role of Mitofusin 2 in Autophagosome-Lysosome Fusion in Cardiomyocytes

Zhao, T. S., Huang, X., Han, L., Wang, X., Cheng, H., Zhao, Y., Chen, Q., Chen, J., Cheng, H., Xiao, R., et al. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.379164 · Cited by 207 · see citing works

INF2 Is a WASP Homology 2 Motif-containing Formin That Severs Actin Filaments and Accelerates Both Polymerization and Depolymerization

Chhabra, E. S., & Higgs, H. N. (2006) · Journal of Biological Chemistry · doi:10.1074/jbc.m604666200 · Cited by 201 · see citing works

Characterization of a microsomal subfraction associated with mitochondria of the yeast, Saccharomyces cerevisiae. Involvement in synthesis and import of phospholipids into mitochondria

Gaigg, B., Simbeni, R., Hrastnik, C., Paltauf, F., & Daum, G. (1995) · Biochimica et Biophysica Acta (BBA) - Biomembranes · doi:10.1016/0005-2736(94)00287-y · Cited by 200 · see citing works

Mitophagy receptor FUNDC1 regulates mitochondrial homeostasis and protects the heart from I/R injury

Zhang, W., Siraj, S., Zhang, R., & Chen, Q. (2017) · Autophagy · doi:10.1080/15548627.2017.1300224 · Cited by 200 · see citing works

Glycogen Synthase Kinase 3 Inhibition Slows Mitochondrial Adenine Nucleotide Transport and Regulates Voltage-Dependent Anion Channel Phosphorylation

Das, S., Wong, R. P., Rajapakse, N. C., Murphy, E., & Steenbergen, C. (2008) · Circulation Research · doi:10.1161/circresaha.108.178970 · Cited by 197 · see citing works

Hearts deficient in both Mfn1 and Mfn2 are protected against acute myocardial infarction

Hall, A. R., Burke, N., Dongworth, R. K., Kalkhoran, S. B., Dyson, A., Vicencio, J. M., Dorn, G. W., Yellon, D. M., & Hausenloy, D. J. (2016) · Cell Death and Disease · doi:10.1038/cddis.2016.139 · Cited by 190 · see citing works

Regulation of the ER stress response by a mitochondrial microprotein

Chu, Q., Martinez, T. F., Novak, S. W., Donaldson, C. J., Tan, D., Vaughan, J. M., Chang, T., Diedrich, J. K., de Andrade, L. R., Kim, A., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12816-z · Cited by 189 · see citing works

Loss of Mitofusin 2 Promotes Endoplasmic Reticulum Stress

Ngoh, G. A., Papanicolaou, K. N., & Walsh, K. (2012) · Journal of Biological Chemistry · doi:10.1074/jbc.m112.359174 · Cited by 183 · see citing works

ER–mitochondria signaling in Parkinson’s disease

Gómez‐Suaga, P., Pedro, J. M. B., González‐Polo, R. A., Fuentes, J. M., & Niso‐Santano, M. (2018) · Cell Death and Disease · doi:10.1038/s41419-017-0079-3 · Cited by 166 · see citing works

Erratum: Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition

Bonora, M., Wieckowsk, M. R., Chinopoulos, C., Kepp, O., Kroemer, G., Galluzzi, L., & Pinton, P. (2015) · Oncogene · doi:10.1038/onc.2014.462 · Cited by 163 · see citing works

HIF-1 reduces ischaemia–reperfusion injury in the heart by targeting the mitochondrial permeability transition pore

Ong, S., Lee, W. H., Theodorou, L., Kodo, K., Lim, S. Y., Shukla, D., Briston, T., Kiriakidis, S., Ashcroft, M. A., Davidson, S. M., et al. (2014) · Cardiovascular Research · doi:10.1093/cvr/cvu172 · Cited by 160 · see citing works

Endoplasmic Reticulum Chaperone GRP78 Protects Heart From Ischemia/Reperfusion Injury Through Akt Activation

Bi, X., Zhang, G., Wang, X., Nguyen, C., May, H. I., Li, X., Al‐Hashimi, A., Austin, R. C., Gillette, T. G., Fu, G., et al. (2018) · Circulation Research · doi:10.1161/circresaha.117.312641 · Cited by 151 · see citing works

Aldehyde dehydrogenase 2 activation in heart failure restores mitochondrial function and improves ventricular function and remodelling

Gomes, M. K., Campos, J. C., Bechara, L. R. G., Queliconi, B. B., Lima, V. M., Disatnik, M., Magno, P., Chen, C., Brum, P. C., Kowaltowski, A. J., et al. (2014) · Cardiovascular Research · doi:10.1093/cvr/cvu125 · Cited by 150 · see citing works

Mitochondrial dynamism and heart disease: changing shape and shaping change

Dorn, G. W. (2015) · EMBO Molecular Medicine · doi:10.15252/emmm.201404575 · Cited by 147 · see citing works

The SR/ER-mitochondria calcium crosstalk is regulated by GSK3β during reperfusion injury

Gomez, L., Thiébaut, P., Paillard, M., Ducreux, S., Abrial, M., Silva, C. C. D., Durand, A., Alam, M. R., Coppenolle, F. V., Sheu, S.-S., et al. (2015) · Cell Death and Differentiation · doi:10.1038/cdd.2015.101 · Cited by 142 · see citing works

FUNDC1 interacts with FBXL2 to govern mitochondrial integrity and cardiac function through an IP3R3-dependent manner in obesity

Ren, J. T., Sun, M., Zhou, H., Ajoolabady, A., Zhou, Y., Tao, J., Sowers, J. R., & Zhang, Y. (2020) · Science Advances · doi:10.1126/sciadv.abc8561 · Cited by 137 · see citing works

Down-regulation of mitofusin-2 expression in cardiac hypertrophy in vitro and in vivo

Lu, F. Y., Moore, X., Gao, X., Dart, A. M., Lim, Y. L., & Du, X. (2007) · Life Sciences · doi:10.1016/j.lfs.2007.04.003 · Cited by 135 · see citing works

Regulation of mitochondrial fission by intracellular Ca2+ in rat ventricular myocytes

Hom, J., Yu, T., Yoon, Y., Porter, G. A., Jr., & Sheu, S. (2010) · Biochimica et Biophysica Acta (BBA) - Bioenergetics · doi:10.1016/j.bbabio.2010.03.018 · Cited by 128 · see citing works

Increased InsP 3 Rs in the junctional sarcoplasmic reticulum augment Ca 2+ transients and arrhythmias associated with cardiac hypertrophy

Harzheim, D., Movassagh, M., Foo, R., Ritter, O., Tashfeen, A., Conway, S. J., Bootman, M. D., & Roderick, H. L. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0905485106 · Cited by 125 · see citing works

MITOL prevents ER stress‐induced apoptosis by IRE1α ubiquitylation at ER–mitochondria contact sites

Takeda, K., Nagashima, S., Shiiba, I., Uda, A., Tokuyama, T., Ito, N., Fukuda, T., Matsushita, N., Ishido, S., Iwawaki, T., et al. (2019) · The EMBO Journal · doi:10.15252/embj.2018100999 · Cited by 123 · see citing works

Mitochondria-associated ER membranes (MAMs) and lysosomal storage diseases

Annunziata, I., Sano, R., & d’Azzo, A. (2018) · Cell Death and Disease · doi:10.1038/s41419-017-0025-4 · Cited by 118 · see citing works

The adenine nucleotide translocator in apoptosis

Belzacq, A.-S., Vieira, H. L. A., Kroemer, G., & Brenner, C. (2002) · Biochimie · doi:10.1016/s0300-9084(02)01366-4 · Cited by 117 · see citing works

Parkin Regulates Programmed Necrosis and Myocardial Ischemia/Reperfusion Injury by Targeting Cyclophilin-D

Sun, T., Ding, W., Xu, T., Ao, X., Yu, T., Li, M., Liu, Y., Zhang, X., Hou, L., & Wang, J. (2019) · Antioxidants and Redox Signaling · doi:10.1089/ars.2019.7734 · Cited by 117 · see citing works

Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation

Goiran, T., Duplan, E., Rouland, L., Manaa, W. E., Lauritzen, I., Dunys, J., You, H., Checler, F., & da Costa, C. A. (2018) · Cell Death and Differentiation · doi:10.1038/s41418-017-0016-0 · Cited by 110 · see citing works

The mitochondria-associated endoplasmic-reticulum subcompartment (MAM fraction) of rat liver contains highly active sphingolipid-specific glycosyltransferases

Ardail, D., Popa, I., Bodennec, J., Louisot, P., Schmitt, D., & Portoukalian, J. (2003) · Biochemical Journal · doi:10.1042/bj20021834 · Cited by 107 · see citing works

LRRK2 regulates endoplasmic reticulum–mitochondrial tethering through the PERK‐mediated ubiquitination pathway

Toyofuku, T., Okamoto, Y., Ishikawa, T., Sasawatari, S., & Kumanogoh, A. (2019) · The EMBO Journal · doi:10.15252/embj.2018100875 · Cited by 107 · see citing works

Coupling of ryanodine receptor 2 and voltage-dependent anion channel 2 is essential for Ca2+ transfer from the sarcoplasmic reticulum to the mitochondria in the heart

Min, C. K., Yeom, D. R., Lee, K., Kwon, H.-K., Kang, M., Kim, Y.-S., Park, Z., Jeon, H., & Kim, D. H. (2012) · Biochemical Journal · doi:10.1042/bj20120705 · Cited by 103 · see citing works

Mitochondrial 4-HNE derived from MAO-A promotes mitoCa2+ overload in chronic postischemic cardiac remodeling

Santin, Y., Fazal, L., Sainte–Marie, Y., Sicard, P., Maggiorani, D., Tortosa, F., Yücel, Y. Y., Teyssedre, L., Rouquette, J., Marcellin, M., et al. (2019) · Cell Death and Differentiation · doi:10.1038/s41418-019-0470-y · Cited by 103 · see citing works

Hyperglycemia Induces Endoplasmic Reticulum Stress in Atrial Cardiomyocytes, and Mitofusin-2 Downregulation Prevents Mitochondrial Dysfunction and Subsequent Cell Death

Yuan, M., Gong, M., Zhang, Z., Meng, L., Tse, G., Zhao, Y., Bao, Q., Zhang, Y., Yuan, M., Liu, X., et al. (2020) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2020/6569728 · Cited by 101 · see citing works

Methylglyoxal-derived advanced glycation end products contribute to negative cardiac remodeling and dysfunction post-myocardial infarction

Blackburn, N. J. R., Vulesevic, B., McNeill, B., Çimenci, Ç. E., Ahmadi, A., Gonzalez-Gomez, M., Ostojic, A., Zhong, Z., Brownlee, M., Beisswenger, P. J., et al. (2017) · Basic Research in Cardiology · doi:10.1007/s00395-017-0646-x · Cited by 97 · see citing works

Polycystin 2 regulates mitochondrial Ca 2+ signaling, bioenergetics, and dynamics through mitofusin 2

Kuo, I. Y., Brill, A. L., Lemos, F. O., Jiang, J., Falcone, J. L., Kimmerling, E. P., Cai, Y., Dong, K., Kaplan, D. L., Wallace, D. P., et al. (2019) · Science Signaling · doi:10.1126/scisignal.aat7397 · Cited by 95 · see citing works

Mitochondrial Ca2+ influx targets cardiolipin to disintegrate respiratory chain complex II for cell death induction

Hwang, M.-S., Schwall, C. T., Pazarentzos, E., Datler, C., Alder, N. N., & Grimm, S. (2014) · Cell Death and Differentiation · doi:10.1038/cdd.2014.84 · Cited by 93 · see citing works

Nox4 regulates InsP3 receptor‐dependent Ca2+ release into mitochondria to promote cell survival

Beretta, M., Santos, C. X., Molenaar, C., Hafstad, A. D., Miller, C. C., Revazian, A., Betteridge, K., Schröder, K., Streckfuß‐Bömeke, K., Doroshow, J. H., et al. (2020) · The EMBO Journal · doi:10.15252/embj.2019103530 · Cited by 93 · see citing works

Interaction of presenilins with FKBP38 promotes apoptosis by reducing mitochondrial Bcl-2

Wang, H.-Q., Nakaya, Y., Du, Z., Yamane, T., Shirane, M., Kudo, T., Takeda, M., Takebayashi, K., Noda, Y., Nakayama, K. I., et al. (2005) · Human Molecular Genetics · doi:10.1093/hmg/ddi195 · Cited by 86 · see citing works

Alteration in mitochondrial Ca 2+ uptake disrupts insulin signaling in hypertrophic cardiomyocytes

Gutiérrez, T., Parra, V., Troncoso, R., Pennanen, C., Contreras‐Ferrat, A. E., Vásquez-Trincado, C., Morales, P. E., López‐Crisosto, C., Sotomayor-Flores, C., Chiong, M., et al. (2014) · Cell Communication and Signaling · doi:10.1186/s12964-014-0068-4 · Cited by 84 · see citing works

Local control of mitochondrial membrane potential, permeability transition pore and reactive oxygen species by calcium and calmodulin in rat ventricular myocytes

Odagiri, K., Katoh, H., Kawashima, H., Tanaka, T. L., Ohtani, H., Saotome, M., Urushida, T., Satoh, H., & Hayashi, H. (2009) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2008.12.022 · Cited by 83 · see citing works

Ryanodine Receptor Glycation Favors Mitochondrial Damage in the Senescent Heart

Ruiz‐Meana, M., Minguet, M., Bou‐Teen, D., Miró‐Casas, E., Castans, C., Castellano, J., Bonzón‐Kulichenko, E., Igual, A., Rodríguez-Lecoq, R., Vázquez, J., et al. (2019) · Circulation · doi:10.1161/circulationaha.118.035869 · Cited by 80 · see citing works

Unsaturated aldehydes including 4-OH-nonenal are elevated in patients with congestive heart failure

Mak, S. S., Lehotay, D. C., Yazdanpanah, M., Azevedo, E. R., Liu, P. P., & Newton, G. E. (2000) · Journal of Cardiac Failure · doi:10.1016/s1071-9164(00)90012-5 · Cited by 77 · see citing works

σ1-Receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunction in mice

Tagashira, H., Bhuiyan, S., Shioda, N., Hasegawa, H., Kanai, H., & Fukunaga, K. (2010) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00198.2010 · Cited by 77 · see citing works

Inositol 1, 4, 5-Triphosphate Receptors and Human Left Ventricular Myocytes

Signore, S., Sorrentino, A., Ferreira-Martins, J., Kannappan, R., Shafaie, M., Ben, F. D., Isobe, K., Arranto, C., Wybieralska, E., Webster, A., et al. (2013) · Circulation · doi:10.1161/circulationaha.113.002764 · Cited by 74 · see citing works

miR-106a promotes cardiac hypertrophy by targeting mitofusin 2

Guan, X., Wang, L., Liu, Z., Guo, X., Jiang, Y., Lu, Y., Peng, Y., Liu, T., Yang, B., Shan, H., et al. (2016) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2016.08.016 · Cited by 74 · see citing works

Mitochondrial fission protein, dynamin-related protein 1, contributes to the promotion of hypertensive cardiac hypertrophy and fibrosis in Dahl-salt sensitive rats

Hasan, P., Saotome, M., Ikoma, T., Iguchi, K., Kawasaki, H., Iwashita, T., Hayashi, H., & Maekawa, Y. (2018) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2018.07.004 · Cited by 72 · see citing works

Alignment of sarcoplasmic reticulum-mitochondrial junctions with mitochondrial contact points

Garcı́a-Pérez, C., Schneider, T. G., Hajnóczky, G., & Csordás, G. (2011) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00397.2011 · Cited by 71 · see citing works

PACS2 is required for ox-LDL-induced endothelial cell apoptosis by regulating mitochondria-associated ER membrane formation and mitochondrial Ca2+ elevation

Yu, S., Zhang, L., Liu, C., Yang, J., Zhang, J., & Huang, L. J. (2019) · Experimental Cell Research · doi:10.1016/j.yexcr.2019.04.002 · Cited by 71 · see citing works

DISC1 Modulates Neuronal Stress Responses by Gate-Keeping ER-Mitochondria Ca2+ Transfer through the MAM

Park, S. J., Lee, S. B., Suh, Y., Kim, S.-J., Lee, N., Hong, J., Park, C., Woo, Y., Ishizuka, K., Kim, J., et al. (2017) · Cell Reports · doi:10.1016/j.celrep.2017.11.043 · Cited by 70 · see citing works

MiR-195-5p Promotes Cardiomyocyte Hypertrophy by Targeting MFN2 and FBXW7

Wang, L., Qin, D., Shi, H., Zhang, Y., Li, H., & Han, Q. (2019) · BioMed Research International · doi:10.1155/2019/1580982 · Cited by 63 · see citing works

ER–mitochondria contacts: Actin dynamics at the ER control mitochondrial fission via calcium release

Steffen, J., & Koehler, C. M. (2017) · The Journal of Cell Biology · doi:10.1083/jcb.201711075 · Cited by 62 · see citing works

Mitofusin 2 Inhibits Angiotensin II-Induced Myocardial Hypertrophy

Yu, H., Guo, Y., Mi, L., Wang, Y., Li, L., & Gao, W. D. (2010) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/1074248410385683 · Cited by 61 · see citing works

PTPIP51 regulates mouse cardiac ischemia/reperfusion through mediating the mitochondria-SR junction

Qiao, X., Shi, J. Y., Ye, J., Fang, X., Zhang, C., Cao, Y., Xu, C., Zhao, L., Zhu, Y., Wang, L., et al. (2017) · Scientific Reports · doi:10.1038/srep45379 · Cited by 61 · see citing works

Targeting sigma-1 receptor with fluvoxamine ameliorates pressure-overload-induced hypertrophy and dysfunctions

Bhuiyan, M. S., Tagashira, H., Shioda, N., & Fukunaga, K. (2010) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2010.509348 · Cited by 56 · see citing works

Expression Profile of microRNAs in Hypertrophic Cardiomyopathy and Effects of microRNA-20 in Inducing Cardiomyocyte Hypertrophy Through Regulating Gene MFN2

Sun, D., Li, C., Liu, J., Wang, Z., Liu, Y., Luo, C., Chen, Y., & Wen, S. (2019) · DNA and Cell Biology · doi:10.1089/dna.2019.4731 · Cited by 56 · see citing works

Protein tyrosine phosphatase interacting protein 51 (PTPIP51) is a novel mitochondria protein with an N-terminal mitochondrial targeting sequence and induces apoptosis

Lv, B., Yu, C. F., Chen, Y. Y., Lu, Y., Guo, J., Song, Q. S., L., D., Shi, T., & Wang, L. (2006) · APOPTOSIS · doi:10.1007/s10495-006-8882-9 · Cited by 55 · see citing works

Cardiac inositol 1,4,5-trisphosphate receptors

Garcia, M. I., & Boehning, D. F. (2016) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2016.11.017 · Cited by 53 · see citing works

Variants in Miro1 Cause Alterations of ER-Mitochondria Contact Sites in Fibroblasts from Parkinson’s Disease Patients

Berenguer-Escuder, C., Großmann, D., Massart, F., Antony, P. M. A., Burbulla, L. F., Glaab, E., Imhoff, S., Trinh, J., Seibler, P., Grünewald, A., et al. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8122226 · Cited by 52 · see citing works

Increased ER–mitochondrial coupling promotes mitochondrial respiration and bioenergetics during early phases of ER stress

Bravo, R., Vicencio, J. M., Parra, V., Troncoso, R., Muñoz, J. P., Bui, M., Quiroga, C., Rodriguez, A. E., Verdejo, H., Ferreira, J., et al. (2011) · Journal of Cell Science · doi:10.1242/jcs.095455 · Cited by 50 · see citing works

FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice

Misaka, T., Murakawa, T., Nishida, K., Omori, Y., Taneike, M., Omiya, S., Molenaar, C., Uno, Y., Yamaguchi, O., Takeda, J., et al. (2017) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2017.11.004 · Cited by 46 · see citing works

Chronic stimulation of the sigma-1 receptor ameliorates autonomic nerve dysfunction and atrial fibrillation susceptibility in a rat model of depression

Liu, X., Qu, C., Yang, H., Shi, S., Zhang, C., Zhang, Y., Liang, J., & Yang, B. (2018) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00607.2017 · Cited by 42 · see citing works

Splenic Ly6Chi monocytes contribute to adverse late post-ischemic left ventricular remodeling in heme oxygenase-1 deficient mice

Tomczyk, M., Kraszewska, I., Szade, K., Bukowska-Straková, K., Meloni, M., Józkowicz, A., Dulak, J., & Jaźwa, A. (2017) · Basic Research in Cardiology · doi:10.1007/s00395-017-0629-y · Cited by 41 · see citing works

Elevated InsP3R expression underlies enhanced calcium fluxes and spontaneous extra-systolic calcium release events in hypertrophic cardiac myocytes

Harzheim, D., Talasila, A., Movassagh, M., Foo, R., Figg, N. L., Bootman, M. D., & Roderick, H. L. (2010) · Channels · doi:10.4161/chan.4.1.10531 · Cited by 38 · see citing works

Diverse regulation of IP3and ryanodine receptors by pentazocine through σ1-receptor in cardiomyocytes

Tagashira, H., Bhuiyan, M. S., & Fukunaga, K. (2013) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00300.2013 · Cited by 38 · see citing works

Parkinson’s disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging

Chen, X., Xie, C., Tian, W., Sun, L., Zheng, W., Hawes, S., Chang, L., Kung, J. E., Ding, J., Chen, S., et al. (2020) · Molecular Neurodegeneration · doi:10.1186/s13024-020-00360-0 · Cited by 38 · see citing works

Regulation of apoptosis and neurite extension by FKBP38 is required for neural tube formation in the mouse

Shirane, M., Ogawa, M., Motoyama, J., & Nakayama, K. I. (2008) · Genes to Cells · doi:10.1111/j.1365-2443.2008.01194.x · Cited by 37 · see citing works

Crucial Interactions Between Selective Serotonin Uptake Inhibitors and Sigma-1 Receptor in Heart Failure

Bhuiyan, M. S., Tagashira, H., & Fukunaga, K. (2013) · Journal of Pharmacological Sciences · doi:10.1254/jphs.12r13cp · Cited by 34 · see citing works

Targeting mitochondria‐associated membranes as a potential therapy against endothelial injury induced by hypoxia

Yang, Y., Li, M., Xu, G., Zhang, E., Chen, J., Sun, B., Chen, D., & Gao, Y. (2019) · Journal of Cellular Biochemistry · doi:10.1002/jcb.29220 · Cited by 30 · see citing works

Correction to: Parkinson’s disease-related Leucine-rich repeat kinase 2 modulates nuclear morphology and genomic stability in striatal projection neurons during aging

Chen, X., Xie, C., Tian, W., Sun, L., Zheng, W., Hawes, S., Chang, L., Kung, J., Ding, J., Chen, S., et al. (2020) · Molecular Neurodegeneration · doi:10.1186/s13024-020-00371-x · Cited by 28 · see citing works

Chapter 6 Cell and Molecular Biology of the Novel Protein Tyrosine‐Phosphatase‐Interacting Protein 51

Stenzinger, A., Schreiner, D., Reiners-Koch, P.-S., Hofer, H. W., & Wimmer, M. A. (2009) · International review of cytology · doi:10.1016/s1937-6448(09)75006-3 · Cited by 27 · see citing works

Role of mitochondrial calcium uniporter in regulating mitochondrial fission in the cerebral cortexes of living rats

Liang, N., Wang, P., Wang, S., Li, S., Li, Y., Wang, J., & Wang, M. (2014) · Journal of Neural Transmission · doi:10.1007/s00702-014-1166-6 · Cited by 22 · see citing works

Ten year mortality in relation to original size of myocardial infarct: results from the Gothenburg metoprolol study.

Herlitz, J. D., Karlson, B. W., & Hjalmarson, Å. (1994) · Heart · doi:10.1136/hrt.71.3.238 · Cited by 14 · see citing works

Cell death regulation by MAMs: from molecular mechanisms to therapeutic implications in cardiovascular diseases

Li, Y. E., Sowers, J. R., Hetz, C. A., & Ren, J. T. (2022) · Cell Death and Disease · doi:10.1038/s41419-022-04942-2 · Cited by 86 · see citing works

Mitochondrial Ca2+ Homeostasis: Emerging Roles and Clinical Significance in Cardiac Remodeling

Zhang, D., Wang, F., Li, P., & Gao, Y. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23063025 · Cited by 75 · see citing works

SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes

Chang, Y., Wang, C., Zhu, J., Zheng, S., Sun, S., Wu, Y., Jiang, X., Li, L., Ma, R., & Li, G. (2023) · Journal of Translational Medicine · doi:10.1186/s12967-023-04246-9 · Cited by 65 · see citing works

The SIRT3-ATAD3A axis regulates MAM dynamics and mitochondrial calcium homeostasis in cardiac hypertrophy

Li, Z., Hu, O., Xu, S., Lin, C., Yu, W., Ma, D., Lu, J., & Liu, P. (2024) · International Journal of Biological Sciences · doi:10.7150/ijbs.89253 · Cited by 50 · see citing works

Cuproptosis, the novel therapeutic mechanism for heart failure: a narrative review

Yuan, H., Xue, Y., & Liu, Y. (2022) · Cardiovascular Diagnosis and Therapy · doi:10.21037/cdt-22-214 · Cited by 45 · see citing works

Endoplasmic Reticulum-Mitochondria Contacts: A Potential Therapy Target for Cardiovascular Remodeling-Associated Diseases

Wang, Y., Zhang, X., Wen, Y., Li, S., Lu, X., Xu, R., & Li, C. (2021) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2021.774989 · Cited by 44 · see citing works

GRP75 Modulates Endoplasmic Reticulum–Mitochondria Coupling and Accelerates Ca2+-Dependent Endothelial Cell Apoptosis in Diabetic Retinopathy

Li, Y., Li, H., Shao, J., Zhu, L., Xie, T., Cai, J., Wang, W., Cai, M.-X., Wang, Z., Yao, Y., et al. (2022) · Biomolecules · doi:10.3390/biom12121778 · Cited by 43 · see citing works

The Mitochondrial‐Associated Endoplasmic Reticulum Membrane and Its Role in Diabetic Nephropathy

Ni, L., & Cheng, Y. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/8054817 · Cited by 35 · see citing works

Mitochondrial Tumor Suppressor 1A Attenuates Myocardial Infarction Injury by Maintaining the Coupling Between Mitochondria and Endoplasmic Reticulum

Gong, Y., Lu, X., Wang, X. T., Wang, Y., Shen, Z., Gao, Y., Zhuang, L., Yu, L., Chen, J. C., Li, Q., et al. (2025) · Circulation · doi:10.1161/circulationaha.124.069737 · Cited by 35 · see citing works

Targeting endoplasmic reticulum stress as a potential therapeutic strategy for diabetic cardiomyopathy

Congur, I., Mingrone, G., & Guan, K. (2024) · Metabolism · doi:10.1016/j.metabol.2024.156062 · Cited by 33 · see citing works

Pterostilbene alleviates liver ischemia/reperfusion injury via PINK1-mediated mitophagy

Shi, Q., Zhao, G., Wei, S., Guo, C., Wu, X., Zhao, R. C., & Di, G. (2021) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2021.09.005 · Cited by 33 · see citing works

Intricate subcellular journey of nanoparticles to the enigmatic domains of endoplasmic reticulum

Girigoswami, K., Pallavi, P., & Girigoswami, A. (2023) · Drug Delivery · doi:10.1080/10717544.2023.2284684 · Cited by 32 · see citing works

Compositions and Functions of Mitochondria-Associated Endoplasmic Reticulum Membranes and Their Contribution to Cardioprotection by Exercise Preconditioning

Lv, Y., Cheng, L., & Peng, F. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.910452 · Cited by 32 · see citing works

Mitofusin2 Ameliorated Endoplasmic Reticulum Stress and Mitochondrial Reactive Oxygen Species Through Maintaining Mitochondria-Associated Endoplasmic Reticulum Membrane Integrity in Cisplatin-Induced Acute Kidney Injury

Liu, Y., Zhang, H., Duan, S.-B., Wang, J., Chen, H., Zhan, M., Zhang, W., Li, A., Liu, Y., Yang, Y., et al. (2023) · Antioxidants and Redox Signaling · doi:10.1089/ars.2022.0178 · Cited by 29 · see citing works

TRPV1 Channels Are New Players in the Reticulum–Mitochondria Ca2+ Coupling in a Rat Cardiomyoblast Cell Line

Tessier, N., Ducrozet, M., Dia, M., Badawi, S., Chouabe, C., Silva, C. C. D., Ovize, M., Bidaux, G., Coppenolle, F. V., & Ducreux, S. (2023) · Cells · doi:10.3390/cells12182322 · Cited by 24 · see citing works

Lactate-Induced Mitochondrial Calcium Uptake 3 Aggravates Myocardial Ischemia–Reperfusion Injury by Promoting Neutrophil Extracellular Trap Formation

Zhang, H., Liu, L., Shen, C., Jiang, X., Liu, J., Chen, J., Xu, S.-L., & Mo, Y. (2025) · Research · doi:10.34133/research.0705 · Cited by 24 · see citing works

Intermittent Hypoxia-Induced Cardiomyocyte Death Is Mediated by HIF-1 Dependent MAM Disruption

Moulin, S., Thomas, A., Wagner, S., Arzt, M. E., Dubouchaud, H., Lamarche, F., Bouyon, S., Vial, G., Godin‐Ribuot, D., Pépin, J., et al. (2022) · Antioxidants · doi:10.3390/antiox11081462 · Cited by 25 · see citing works

Exerkines and Sarcopenia: Unveiling the Mechanism Behind Exercise-Induced Mitochondrial Homeostasis

Wang, J., Jia, D., Zhang, Z., & Wang, D. (2025) · Metabolites · doi:10.3390/metabo15010059 · Cited by 23 · see citing works

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Chu, H., Qin, Z., Ma, J., Xie, Y., Shi, H., Gu, J., & Shi, B. (2022) · Cells · doi:10.3390/cells11193075 · Cited by 21 · see citing works

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Chen, X., Yang, Y., Zhou, Z., Yu, H., Zhang, S., Huang, S., Wei, Z., Ren, K., & Jin, Y. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112930 · Cited by 19 · see citing works

The Research Progress of Mitochondrial Transplantation in the Treatment of Mitochondrial Defective Diseases

Hu, C., Shi, Z., Liu, X., & Sun, C. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25021175 · Cited by 18 · see citing works

Calcium signaling from sarcoplasmic reticulum and mitochondria contact sites in acute myocardial infarction

Agyapong, E. D., Pedriali, G., Ramaccini, D., Bouhamida, E., Tremoli, E., Giorgi, C., Pinton, P., & Morciano, G. (2024) · Journal of Translational Medicine · doi:10.1186/s12967-024-05240-5 · Cited by 17 · see citing works

Deciphering the mitochondria-inflammation axis: Insights and therapeutic strategies for heart failure

Zuo, B., Xiu, F., Xu, D., Zhao, L., Zhang, B., & Li, X. (2024) · International Immunopharmacology · doi:10.1016/j.intimp.2024.112697 · Cited by 18 · see citing works

Contribution and therapeutic value of mitophagy in cerebral ischemia-reperfusion injury after cardiac arrest

Li, Z., & Xing, J. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115492 · Cited by 14 · see citing works

Mitochondria‐Associated Endoplasmic Reticulum Membranes in Health and Diseases

Hong, H., Guo, Z., Ge, J., & Li, H. (2025) · MedComm · doi:10.1002/mco2.70379 · Cited by 14 · see citing works

The histone deacetylase inhibitor SAHA exerts a protective effect against myocardial ischemia/reperfusion injury by inhibiting sodium-calcium exchanger

Shi, X., Yin, Y., Guo, X., Liu, M., Ma, F., Li, T. X., Zheng, M., & Liu, G. (2023) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2023.05.120 · Cited by 13 · see citing works

Small-molecule fluorescent probes for imaging and diagnosing ischemia-reperfusion injury

Guo, Q., Liu, A., Huang, Y., Ding, J., Ding, J., Wang, L., Ding, Y., Peng, B., Li, L., Fang, B., et al. (2025) · Chinese Chemical Letters · doi:10.1016/j.cclet.2025.110943 · Cited by 13 · see citing works

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Pei, L., Yao, Z., Liang, D., Yang, K., & Tao, L. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.117505 · Cited by 12 · see citing works

Cold inducible RNA binding protein-regulated mitochondria associated endoplasmic reticulum membranes-mediated Ca2+ transport play a critical role in hypothermia cerebral resuscitation

Gao, Y., Liu, H., Zhou, Y., Cai, S., Zhang, J., Sun, J., & Duan, M. (2024) · Experimental Neurology · doi:10.1016/j.expneurol.2024.114883 · Cited by 9 · see citing works

The role of mitochondria-associated ER membranes in disease pathology: protein complex and therapeutic targets

Zhang, J., Li, D., Zhou, L., Li, Y., Xi, Q., Zhang, L.-Y., & Zhang, J. (2025) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2025.1629568 · Cited by 9 · see citing works

Targeting mitochondrial circadian rhythms: The potential intervention strategies of Traditional Chinese medicine for myocardial ischaemia‒reperfusion injury

Song, Z., Yang, Z., Tian, L., Liu, Y., Guo, Z., Zhang, Q., Zhang, Y., Wen, T., Xu, H., Li, Z., et al. (2023) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2023.115432 · Cited by 9 · see citing works

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Zhang, J., Jing, T., Zhou, Z., Pei, W., Xiao, Y., Guo, Y., Gao, J., Jiang, C., Dai, L., Zhang, G., et al. (2025) · Molecular Medicine Reports · doi:10.3892/mmr.2025.13506 · Cited by 8 · see citing works

PPARγ Mediates the Cardioprotective Roles of Danlou Tablet After Acute Myocardial Ischemia-Reperfusion Injury

Meng, W., Guo, M., Meng, X., Li, L., Wang, H., Zhang, M., & Bei, Y. (2022) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2022.858909 · Cited by 8 · see citing works

WITHDRAWN: GRP75 modulates endoplasmic reticulum-mitochondria coupling and accelerates Ca 2+ -dependent endothelial cells apoptosis in diabetic retinopathyPreprint

Li, Y., Li, H., Shao, J., Zhu, L., Xie, T., Cai, J., Wang, W., Cai, M.-X., Wang, Z., Yao, Y., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-2093332/v1 · Cited by 7 · see citing works

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Huang, X., Jiang, D., Feng, X., & Fang, Z.-M. (2024) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2024.176698 · Cited by 6 · see citing works

FL3 mitigates cardiac ischemia-reperfusion injury by promoting mitochondrial fusion to restore calcium homeostasis

Zhong, Z., Hou, Y., Zhou, C., Wang, J., Gao, L., Wu, X., Zhou, G., Liu, S., Xu, Y., & Yang, W. (2025) · Cell Death Discovery · doi:10.1038/s41420-025-02575-w · Cited by 6 · see citing works

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Zheng, H., Zhang, H., Wang, J., Jia, G.-Y., Zhao, Z., & Niu, C. (2024) · Shock · doi:10.1097/shk.0000000000002424 · Cited by 5 · see citing works

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Fitts, R. H., Wang, X., Kwok, W., & Camara, A. K. S. (2024) · International Journal of Sports Medicine · doi:10.1055/a-2296-7604 · Cited by 5 · see citing works

Transmembrane BAX inhibitor motif containing 6 suppresses presenilin-2 to preserve mitochondrial integrity after myocardial ischemia-reperfusion injury

Ma, L., Liao, L., Zhou, N., Tao, H., Zhou, H., Tan, Y., Chen, W., Cao, F., & Chen, X. (2023) · International Journal of Biological Sciences · doi:10.7150/ijbs.81100 · Cited by 5 · see citing works

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Roumeliotis, S. K., Liakopoulos, V., Veljkovic, A., & Dounousi, E. C. (2023) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2023/9864037 · Cited by 5 · see citing works

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Ruan, X., & Zhao, W. (2025) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2025.1546325 · Cited by 4 · see citing works

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Wu, H., Diao, H., Zhang, F., Jiang, W., Pan, T., & Bian, Y. (2025) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2025.117978 · Cited by 3 · see citing works

Genome-wide KAS-Seq mapping of leukocytes in ischemia-reperfusion model reveals IL7R as a potential therapeutic target for ischemia-reperfusion injury

Zhang, L., Duolikun, M., Chen, H., Wang, Z.-H., Li, X., Xiao, H., Dong, Y., Chen, H., Liu, F., Fan, S., et al. (2025) · Scientific Reports · doi:10.1038/s41598-025-90457-7 · Cited by 2 · see citing works

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Fernández‐Sanz, C., Sheu, S., & de la Fuente, S. (2025) · Cells · doi:10.3390/cells14221762 · Cited by 2 · see citing works

Neutrophils and neutrophil extracellular traps in ischaemia–reperfusion injury: pathophysiological roles and therapeutic potential

Zhang, Y., Li, C., Jiang, Q., Yang, Y., Jiang, Y., Chen, L., Wei, X., Xiao, J., & Li, C. (2026) · Burns & Trauma · doi:10.1093/burnst/tkag022 · Cited by 2 · see citing works

Alterbrassacids A and B: Two Novel Fusicoccane Diterpenoids with Protective Activity Against H2O2-Induced Cardiomyocyte Injury from the Fungus Alternaria brassicicola

Jiang, R., Yang, S., Guo, J., Zhang, Y., Hu, Z., Guo, J., Jin, X., Wei, J., & Sun, W. (2025) · Synlett · doi:10.1055/s-0043-1775448 · Cited by 1 · see citing works

CACNB4 attenuates cardiac dysfunction by regulating calcium and ATP levels via interaction with RyR2

Jiang, S., Hong, M., Zhang, J., Xu, F., Zhang, X., & Zhang, G. (2025) · European journal of medical research · doi:10.1186/s40001-025-03322-8 · Cited by 1 · see citing works

WITHDRAWN: GRP75 modulates endoplasmic reticulum-mitochondria coupling and accelerates Ca 2+ -dependent endothelial cells apoptosis in diabetic retinopathyPreprint

(2022) · Research Square · doi:10.21203/rs.3.rs-2093332/v2

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Naman, T., Mahemuti, A., Aslam, N., & Aimaier, S. (2023) · MEDS Basic Medicine · doi:10.23977/medbm.2023.010216

Preconditioning with hydrogen gas produces cardioprotective effects through autophagy activation in rat cardiomyocytes

Yamada, T., Kimura, A., Juri, T., Suehiro, K., & Mori, T. (2025) · BMC Pharmacology and Toxicology · doi:10.1186/s40360-025-01032-9

Additional file 1 of SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes

Chang, Y., Wang, C., Zhu, J., Zheng, S., Sun, S., Wu, Y., Jiang, X., Li, L., Ma, R., & Li, G. (2024) · Figshare · doi:10.6084/m9.figshare.26605984

Additional file 2 of SIRT3 ameliorates diabetes-associated cognitive dysfunction via regulating mitochondria-associated ER membranes

Chang, Y., Wang, C., Zhu, J., Zheng, S., Sun, S., Wu, Y., Jiang, X., Li, L., Ma, R., & Li, G. (2024) · Figshare · doi:10.6084/m9.figshare.26605987

UBA1 Mitigates Myocardial Ischemia/Reperfusion Injury by Attenuating Endoplasmic Reticulum-Mitochondria Contacts via Pdzd8 ubiquitinationPreprint

Xu, L.-L., Li, P., Jiang, W., Du, J., & Huihua, L. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.01.21.700963

Targeting endoplasmic reticulum stress for neuroprotection in ischemia-reperfusion injury: mechanisms and therapeutic approaches

Payal, N., Choudhary, R. C., Sharma, A., & Sharma, L. (2026) · Molecular Biology Reports · doi:10.1007/s11033-026-11915-7

Huoxue Qianyang Qutan Recipe limits cardiac remodeling by regulating FUNDC1/IP3R2 signaling pathway in obese hypertensive rats

Hou, C., Zhao, Y., Ma, Y. Q., Zhou, X., Yao, L., Li, J., Gui, M., Wang, M., Chen, X., Fu, D., et al. (2026) · Scientific Reports · doi:10.1038/s41598-026-56197-y

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Aimaier, S., Naman, T., Abudouwayiti, A., Abuduhalike, R., Sun, J., & Mahemuti, A. (2026) · European journal of medical research · doi:10.1186/s40001-026-04686-1

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Zhang, Q., Gao, J., Yang, Y., Guo, P., Gao, H., Zhao, S., 张双林, Shi, Y., Xie, G., Han, Y., et al. (2026) · Cell Communication and Signaling · doi:10.1186/s12964-026-03013-9

Molecular and Cellular Characterization of Core Genes Associated with Endoplasmic Reticulum Stress in Myocardial Ischemia-Reperfusion Injury

Yuan, H., Wang, L., Chen, Z., Liu, T., Wang, Y., Zhang, S., & Liu, Z. (2026) · Genes · doi:10.3390/genes17111352

MAMs-Mediated Calcium Homeostasis in the Pathophysiology of Cardiovascular Diseases: A Mini-Review

Fan, M., Liu, F., Wang, Y., Shi, W., & 张丽净 (2026) · Drug Design Development and Therapy · doi:10.2147/dddt.s641584

Potential Role of Mitochondria-Associated Endoplasmic Reticulum Membranes in Heart Failure

Naman, T., Mahemuti, A., Aslam, N., & Aimaier, S. (2023) · MEDS Basic Medicine · doi:10.23977/medbm.2023.010216

Mitochondria-Associated Endoplasmic Reticulum Membranes in Cardiovascular Diseases

Gao, P., Yan, Z., & Zhu, Z. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.604240 · Cited by 129 · see citing works

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Zhang, Y., Yao, J., Zhang, M., Wang, Y., & Shi, X. (2023) · Frontiers in Cardiovascular Medicine · doi:10.3389/fcvm.2023.1083935 · Cited by 31 · see citing works

Mitochondria-associated endoplasmic reticulum membranes: Emerging regulators of cardiac microvascular ischemia/reperfusion injury (Review)

Wang, Y., Feng, B., Wu, Y.-T., Sun, Z., Yuan, H., Chen, W., Zhao, C.-Q., & Liu, Z. (2025) · International Journal of Molecular Medicine · doi:10.3892/ijmm.2025.5705 · Cited by 4 · see citing works