The DOI matches its Crossref record; 597 of the 597 references it cites were found in a registry or an index.
Physiological and molecular determinants of embryo implantation
Open accessAbstract
Embryo implantation involves the intimate interaction between an implantation-competent blastocyst and a receptive uterus, which occurs in a limited time period known as the window of implantation. Emerging evidence shows that defects originating during embryo implantation induce ripple effects with adverse consequences on later gestation events, highlighting the significance of this event for pregnancy success. Although a multitude of cellular events and molecular pathways involved in embryo-uterine crosstalk during implantation have been identified through gene expression studies and genetically engineered mouse models, a comprehensive understanding of the nature of embryo implantation is still missing. This review focuses on recent progress with particular attention to physiological and molecular determinants of blastocyst activation, uterine receptivity, blastocyst attachment and uterine decidualization. A better understanding of underlying mechanisms governing embryo implantation should generate new strategies to rectify implantation failure and improve pregnancy rates in women.
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Cited by
Clearance of senescent decidual cells by uterine natural killer cells in cycling human endometrium
Brighton, P. J., Maruyama, Y., Fishwick, K., Vrljicak, P., Tewary, S., Fujihara, R., Muter, J., Lucas, E. S., Yamada, T., Woods, L., et al. (2017) · eLife · doi:10.7554/elife.31274 · Cited by 323
Biological Roles of Uterine Glands in Pregnancy
Spencer, T. (2014) · Seminars in Reproductive Medicine · doi:10.1055/s-0034-1376354 · Cited by 115
Cell signaling in trophoblast-uterine communication
Fritz, R., Jain, C., & Armant, D. R. (2014) · The International Journal of Developmental Biology · doi:10.1387/ijdb.140011da · Cited by 86
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Zheng, X., Huang, R., Yin, L., Yao, M., Chu, J., Yang, F., Dong, Y., Zhao, M., & Ma, T. (2025) · Acta Biomaterialia · doi:10.1016/j.actbio.2025.01.062 · Cited by 33
Metadata
- Authors
- Zhang, S., Lin, H., Kong, S., Wang, S., Wang, H., Wang, H., & Armant, D. R.
- Venue
- Molecular Aspects of Medicine
- Publisher
- Elsevier BV
- Published
- 2013-10
- Volume
- 34
- Issue
- 5
- Pages
- 939-980
- ISSN
- 0098-2997 (ISSN-L)
- OpenAlex
- W2164576139
- Cited by
- 587
- References
- 597
- FWCI
- 14.47
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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