The DOI matches its Crossref record; 173 of the 174 references it cites were found in a registry or an index.
Interactions between gut bacteria and bile in health and disease
Abstract
Bile acids are synthesized from cholesterol in the liver and released into the intestine to aid the digestion of dietary lipids. The host enzymes that contribute to bile acid synthesis in the liver and the regulatory pathways that influence the composition of the total bile acid pool in the host have been well established. In addition, the gut microbiota provides unique contributions to the diversity of bile acids in the bile acid pool. Gut microbial enzymes contribute significantly to bile acid metabolism through deconjugation and dehydroxylation reactions to generate unconjugated bile acids and secondary bile acids. These microbial enzymes (which include bile salt hydrolase (BSH) and bile acid-inducible (BAI) enzymes) are essential for bile acid homeostasis in the host and represent a vital contribution of the gut microbiome to host health. Perturbation of the gut microbiota in disease states may therefore significantly influence bile acid signatures in the host, especially in the context of gastrointestinal or systemic disease. Given that bile acids are ligands for host cell receptors (including the FXR, TGR5 and Vitamin D Receptor) alterations to microbial enzymes and associated changes to bile acid signatures have significant consequences for the host. In this review we examine the contribution of microbial enzymes to the process of bile acid metabolism in the host and discuss the implications for microbe-host signalling in the context of C. difficile infection, inflammatory bowel disease and other disease states.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“BA transformation by BSH-competent bacteria determines the magnitude of BA-induced nuclear FXR activation in the gut (Long et al., 2017; Sun et al., 2018).”
From Bacteroides dorei BDX-01 alleviates DSS-induced experimental colitis in mice by regulating intestinal bile salt hydrolase activity and the FXR-NLRP3 signaling pathway (2023) · cites this paper as Long et al., 2017
In the citing paper
“these enzymes have an important role in the enterohepatic cycling of endogenous substances such as bile acids (Long et al., 2017).”
From Gut reactions: Breaking down xenobiotic–microbiome interactions (2019) · cites this paper as Long et al., 2017
Citations
Cites
Inference of Macromolecular Assemblies from Crystalline State
Krissinel, E., & Henrick, K. (2007) · Journal of Molecular Biology · doi:10.1016/j.jmb.2007.05.022 · Cited by 10,007
Richness of human gut microbiome correlates with metabolic markers
Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J.-M., Kennedy, S., et al. (2013) · Nature · doi:10.1038/nature12506 · Cited by 4,662
Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis
Koeth, R. A., Wang, Z., Levison, B. S., Buffa, J. A., Org, E., Sheehy, B. T., Britt, E. B., Fu, X., Wu, Y., Li, L., et al. (2013) · Nature Medicine · doi:10.1038/nm.3145 · Cited by 4,386
Gut microbiota composition correlates with diet and health in the elderly
Claesson, M. J., Jeffery, I. B., Conde, S., Power, S. E., O’Connor, E. M., Cusack, S., Harris, H. M. B., Coakley, M., Lakshminarayanan, B., O’Sullivan, O., et al. (2012) · Nature · doi:10.1038/nature11319 · Cited by 3,314
Gut metagenome in European women with normal, impaired and diabetic glucose control
Karlsson, F. H., Tremaroli, V., Nookaew, I., Bergström, G., Behre, C. J., Fagerberg, B., Nielsen, J., & Bäckhed, F. (2013) · Nature · doi:10.1038/nature12198 · Cited by 3,115
Bile salt biotransformations by human intestinal bacteria
Ridlon, J. M., Kang, D.-J., & Hylemon, P. B. (2006) · Journal of Lipid Research · doi:10.1194/jlr.r500013-jlr200 · Cited by 2,829
Sayin, S. I., Wahlström, A., Felin, J., Jäntti, S., Marschall, H.-U., Bamberg, K., Angelin, B., Hyötyläinen, T., Orešič, M., & Bäckhed, F. (2013) · Cell Metabolism · doi:10.1016/j.cmet.2013.01.003 · Cited by 2,331
Bile Acids: Natural Ligands for an Orphan Nuclear Receptor
Parks, D. J., Blanchard, S. G., Bledsoe, R. K., Chandra, G., Consler, T. G., Kliewer, S. A., Stimmel, J. B., Willson, T. M., Zavacki, A. M., Moore, D. D., et al. (1999) · Science · doi:10.1126/science.284.5418.1365 · Cited by 2,274
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
Watanabe, M., Houten, S. M., Mataki, C., Christoffolete, M. A., Kim, B. W., Sato, H., Messaddeq, N., Harney, J. W., Ezaki, O., Kodama, T., et al. (2006) · Nature · doi:10.1038/nature04330 · Cited by 2,220
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
Yoshimoto, S., Loo, T. M., Atarashi, K., Kanda, H., Sato, S., Oyadomari, S., Iwakura, Y., Oshima, K., Morita, H., Hattori, M., et al. (2013) · Nature · doi:10.1038/nature12347 · Cited by 2,219
Flagged first, then by citations
1 of the 174 references couldn’t be matched to a known paper.
Research works printed but not linked: 2
- Branton, 2011, In vitro characterization and safety of the probiotic strain Lactobacillus reuteri cardioviva NCIMB 30242, Int. J. Probiotics Prebiotics, 6, 1
- Gu, 2014, Cloning and analysis of bile salt hydrolase genes from Lactobacillus plantarum CGMCC No. 8198, Biotechnol. Lett., 36, 975, 10.1007/s10529-013-1434-9 · DOI
Cited by
Sorted by citations
Items 401–496 of 496
Gál, E., Parvaneh, S., Miklós, V., Hegyi, P. J., Kemény, L. V., Veréb, Z., & Venglovecz, V. (2024) · Journal of Biotechnology · doi:10.1016/j.jbiotec.2024.05.010 · Cited by 2
Li, W., Shi, A., Liu, X., Zhang, Y., Lu, Y., Dong, L., Wang, J., Zhang, Y., & Wang, S. (2024) · Food Science and Human Wellness · doi:10.26599/fshw.2024.9250237 · Cited by 2
Cussotto, S., Golubeva, A. V., Gallardo, A. L., Bastiaanssen, T. F. S., Zhdanov, A. V., Moloney, G. M., Scaife, C., English, J. A., Joyce, S. A., Dinan, T. G., et al. (2025) · Experimental Physiology · doi:10.1113/ep092451 · Cited by 2
Self-citationModern biological connotation of diarrhea with kidney-Yang deficiency syndrome
Li, X., & Tan, Z. (2022) · World Chinese Journal of Digestology · doi:10.11569/wcjd.v30.i3.119 · Cited by 2
Topic: Nutrition and the Gut-Liver-Brain Axis
Ho, A. H. Y., Wong, S. H., & Lui, R. N.-S. (2022) · Current Hepatology Reports · doi:10.1007/s11901-022-00589-x · Cited by 3
Research Status of Correlation between Gallbladder Cholesterol Stones and Human Microbiota
王, 晓. (2023) · Advances in Clinical Medicine · doi:10.12677/acm.2023.13112578 · Cited by 2
Ke, F., Dong, Z.-H., Bu, F., Li, C., He, Q.-T., Liu, Z.-C., Ji, L., Yu, K., Wang, D., Xu, H.-N., et al. (2024) · World Journal of Gastrointestinal Surgery · doi:10.4240/wjgs.v16.i9.3048 · Cited by 2
Jin, Y., Hu, L., Wang, X., Bao, Z., Xu, Q., & Qian, M. (2022) · SSRN Electronic Journal · doi:10.2139/ssrn.4108564 · Cited by 2
Chai, X., Tang, Y., Li, X., Zou, S., Guan, X., Zang, W., & Wang, T. (2024) · Research Square · doi:10.21203/rs.3.rs-4024621/v1 · Cited by 2
Porcine gut microbiota and lipid metabolism: recent advances and future directions
Ma, Y., Liu, J., & Wang, H. (2022) · Scientia Sinica Vitae · doi:10.1360/ssv-2021-0363 · Cited by 1
Alzoufairi, S., Pushpass, R.-A. G., Jackson, K. G., & Lovegrove, J. A. (2022) · Proceedings of The Nutrition Society · doi:10.1017/s0029665122002270 · Cited by 1
Kaur, S., Diwan, F., & Reddersen, B. (2022) · Applied Microbiology Theory & Technology · doi:10.37256/amtt.4120232096 · Cited by 1
Tanaka, Y., Inaba, C., Sawa, T., Endo, K., Saiki, T., Haga, H., & Tanaka, S. (2023) · Bioscience Biotechnology and Biochemistry · doi:10.1093/bbb/zbad086 · Cited by 1
Getachew, T., Ashenafi, M., Tigu, F., Birri, D. J., Naoli, A., & Desalegn, A. (2025) · BMC Microbiology · doi:10.1186/s12866-025-04326-4 · Cited by 1
Zhang, L., Li, Y., Zhang, J., Zhang, M., & Chen, W. (2025) · iScience · doi:10.1016/j.isci.2025.113781 · Cited by 1
Curley, C. E., Mobbs, C. L., Mroz, M. S., McLean, M. H., & Keely, S. J. (2025) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00341.2025 · Cited by 1
Bile Acid Sequestration Attenuates Desulfovibrio-Induced Hepatic Injury
Yang, S., Zhou, L., Dong, J., Wang, S., Xue, Y., Ren, Y., & Geng, Y. (2025) · Microorganisms · doi:10.3390/microorganisms14010079 · Cited by 1
Yang, R., Zhou, Y., Shen, Y., Liu, J., Shi, Y., & Yang, Y. (2026) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x26500011 · Cited by 1
Chen, Y., & Liu, C. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1735850 · Cited by 1
Song, L., Gao, Y., ABUDULI, S., ABUDUREYIMU, K., Shao, W., Yang, L., Wei, Y., Luo, Y., & Ren, W. (2026) · Animal Feed Science and Technology · doi:10.1016/j.anifeedsci.2026.116682 · Cited by 1
Dietary Fiber Alleviates Gut Microbiota Dysbiosis Caused by High Bile Acids
Shi, L., Wu, D., Xiang, S., Sun, N., & Zhu, X. (2026) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c16816 · Cited by 2
Guo, J., Du, M., & Wang, Y. (2026) · Food & Function · doi:10.1039/d5fo01634g · Cited by 1
Rode, A. A., Duboc, H., Lamazière, A., Rainteau, D. P., Humbert, L., Gauliard, E., Chehri, M., Petersen, A. M., Helms, M., Schønning, K., et al. (2026) · Gut Microbes · doi:10.1080/19490976.2026.2658915 · Cited by 1
Ishikawa, R., Nakamura, M., Sakurai, A., Nakayama-Imaohji, H., Kuwahara, T., Ichimura‐Shimizu, M., Shishibori, M., & Kataoka, K. (2026) · The Journal of Medical Investigation · doi:10.2152/jmi.73.186 · Cited by 1
Abbas, A., Weiskirchen, R., Bilal, M., Afzal, M. K., Malik, A., Akhtar, S., Khan, M., Rashid, I., Khalid, F., Akram, S., et al. (2026) · Pharmaceuticals · doi:10.3390/ph19081184 · Cited by 1
Liao, G., Zhu, M., Zhang, Y., Zhai, S., Chen, C., Yan, Z., Fu, L., Zheng, L., Song, C., Yu, Y., et al. (2026) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2026.122263 · Cited by 1
Role of Gut Microbiota in Bile-Acid Metabolism
Naito, Y., Takagi, T., & Inoüe, R. (2021) · IntechOpen eBooks · doi:10.5772/intechopen.100440 · Cited by 1
Keuler, T., Wolf, V., Lemke, C., Voget, R., Braune, A., & Gütschow, M. (2023) · Bioorganic Chemistry · doi:10.1016/j.bioorg.2023.106574 · Cited by 1
Gut Microbiota and Their Metabolites as Modulators of Vascular Complications in Diabetes
Duan, M. Y., Wen, J., Chen, A., & Chen, S. (2025) · Health and Metabolism · doi:10.53941/hm.2025.100002 · Cited by 1
Alexander, C., Cross, T.-W., Lee, A. H., Ly, L. K., Vieson, M. D., Ridlon, J. M., Nelson, E. R., & Swanson, K. S. (2021) · BMC Gastroenterology · doi:10.1186/s12876-021-01648-1 · Cited by 1
Influence of the gut microbiome on plasma metabolite patterns
Behr, C. (2019) · doi:10.18174/463891 · Cited by 1
Wei, X., & Yuan, J. (2019) · Research Square · doi:10.21203/rs.2.15183/v1 · Cited by 1
The prebiotic effects of amadumbe (Colocasia Esculenta) and okra (Abelmoschus esculentus) mucilage
Gajadhar, S. (2023) · DUT Open Scholar (Durban University of Technology) · doi:10.51415/10321/4803 · Cited by 1
Advanced Progression in the Mechanism of Bile Acid Metabolism Targeting FXR
杨, 修. (2018) · Hans Journal of Biomedicine · doi:10.12677/hjbm.2018.84008
Schönfeld, P., & Meyer, F. P. (2020) · Zeitschrift für Gastroenterologie · doi:10.1055/a-1071-8219
Clinical efficacy of drugs based on probiotic strains of Saccharomyces boulardii
Drozdov, V. N., Arefev, K. I., Serebrova, S. Y., & Ших, Е. В. (2020) · Meditsinskiy sovet = Medical Council · doi:10.21518/2079-701x-2020-5-104-112 · Cited by 1
The Microbiota-Gut-Liver Axis: Implications for the Pathophysiology of Liver Disease
Quigley, E. M. M. (2020) · Springer eBooks · doi:10.1007/978-3-030-51709-0_8 · Cited by 1
Bile acids, non-alcoholic fatty liver and pancreatic disease: chained by ursodeoxycholic acid?
Губергриц, Н. Б., Byelyayeva, N. V., & Mozhynа, T. L. (2020) · Herald of Pancreatic Club · doi:10.33149/vkp.2020.04.03
Gut-Hepatic Relationship: From Disorders of the Gut Microbiota to Hepatocellular Carcinoma
Murkamilov, I. T. (2021) · American Journal of Biomedical Science & Research · doi:10.34297/ajbsr.2021.11.001681
Microbiome Management of Neurological Disorders
Ortíz, G. G., Bitzer-Quintero, O. K., Niño, C. L. C., Ramírez-Jirano, L. J., González-Usigli, H., Pacheco-Moisés, F. P., Torres-Mendoza, B. M., Mireles-Ramírez, M. A., Hernández-Cruz, J. J., & Delgado-Lara, D. L. C. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-819265-8.00003-6
Li, Y., Xu, W., Zhang, F., Zhong, S. S., Sun, Y., Huo, J., Zhu, J., & Wu, C. (2020) · SSRN Electronic Journal · doi:10.2139/ssrn.3559537
Gravity anomalies in Maine: Chapter 31
Kane, M. F., & Bromery, R. W. (1968)
Modern Clinical Course of Cholelithiasis in the Far North
Tyaptirgyanova, T. M., & Tyaptirgyanov, M. M. (2022) · Advances in health sciences research/Advances in Health Sciences Research · doi:10.2991/ahsr.k.220103.048
Evaluation of bile sterility in patients undergoing liver resection
Piątek, B., Majos, A., Grząsiak, O., & Strzelczyk, J. (2022) · Polish Journal of Surgery · doi:10.5604/01.3001.0015.7343
Rational selection and Characterisation of bile acid (BA) metabolising species of infant originPreprint
Long, S. L., & Joyce, S. A. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.06.24.497474
Self-citationPlasma Markers of Cholestasis in Critical Illness
Langouche, L., Gunst, J., & Blaser, A. R. (2022) · Biomarkers in disease · doi:10.1007/978-3-030-87302-8_11-1
Gut microbiome interventions in regenerative medicine
Assalin, H. B., Santos, A., de Souza, A. B., & Bastos, R. G. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-90471-1.00006-2
Ceylani, T., & Teker, H. T. (2023) · Bitlis Eren Üniversitesi Fen Bilimleri Dergisi · doi:10.17798/bitlisfen.1231238
Plasma Markers of Cholestasis in Critical Illness
Langouche, L., Gunst, J., & Blaser, A. R. (2023) · Biomarkers in disease · doi:10.1007/978-3-031-07395-3_11
Liu, G., & Mingyan, E. (2023) · PubMed Central · doi:10.3779/j.issn.1009-3419.2023.106.11
Nutritional Care for Cancer with Sustainable Diets: A Practical Guide
Shaida, B., Rastogi, M., & Rikhari, A. (2024) · World sustainability series · doi:10.1007/978-3-031-47122-3_8
Microbiota to brain communication
Foster, J. A., & Clarke, G. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-814800-6.00007-8
Probiotics: Healthy Gut Microbiota to Lead a Wholesome Life
Kowsaly, M., Deepakala, B., Velmurugan, T., & Rajeshkumar, M. P. (2024) · International Journal of Nature Science. · doi:10.51470/ijns.2024.01.01.15
Microbiome Manipulation in Coloproctology
Suss, N. R., & Shogan, B. D. (2024) · Springer eBooks · doi:10.1007/978-3-031-59630-8_12
Primary biliary cholangitis, a rising health burden
Elnaggar, M., Elkhattib, I., Abomhya, A., & Boyer, J. L. (2024) · Exploration of Immunology · doi:10.37349/ei.2024.00165
Use of Postbiotics in the Poultry Industry: Current Knowledge and Future Prospects
El‐Wahab, A. A., Visscher, C., & Shehata, A. A. (2024) · Springer eBooks · doi:10.1007/978-3-031-70480-2_6 · Cited by 1
Microbiota, metabolic disorders, and pharmacological opportunities
Martín-Chaves, L., de Fonseca, F. R., Jiménez-Navarro, M. F., Criado, A. S., & Pavón, F. J. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-27370-4.00030-5
Shevlyukova, T. P., Bulatova, I. A., Vladimirskiy, V. E., Смирнова, E. N., Trofimova, E. S., & Yusupova, A. A. (2025) · Perm Medical Journal · doi:10.17816/pmj42420-40
Long, Q., Li, L., Tan, Z., & Deng, N. (2025) · Frontiers in Microbiology · doi:10.3389/fmicb.2025.1610928
Ye, M., Sun, J., Chen, Y., Ren, Q., Li, Z., Zhao, Y., Pan, Y., & Xue, H. (2021) · Figshare · doi:10.6084/m9.figshare.14433560
Kim, Y. S., Unno, T., Park, S.-Y., Chung, J. O., Choi, Y.-D., Lee, S.-M., Cho, S. H., Kim, D. H., Kim, H.-S., & Jung, Y. D. (2024) · Figshare · doi:10.6084/m9.figshare.26717391
Kim, Y. S., Unno, T., Park, S.-Y., Chung, J. O., Choi, Y.-D., Lee, S.-M., Cho, S. H., Kim, D. H., Kim, H.-S., & Jung, Y. D. (2024) · Figshare · doi:10.6084/m9.figshare.26717397
Kim, Y. S., Unno, T., Park, S.-Y., Chung, J. O., Choi, Y.-D., Lee, S.-M., Cho, S. H., Kim, D. H., Kim, H.-S., & Jung, Y. D. (2024) · Figshare · doi:10.6084/m9.figshare.25770507
da Silva, T. C. A., dos Santos Gonçalves, J. A., Souza, L. A. C. E., Lima, A. A., & Guerra‐Sá, R. (2023) · Figshare · doi:10.6084/m9.figshare.22614772
Ye, M., Sun, J., Chen, Y., Ren, Q., Li, Z., Zhao, Y., Pan, Y., & Xue, H. (2021) · Figshare · doi:10.6084/m9.figshare.14433557
Kim, Y. S., Unno, T., Park, S.-Y., Chung, J. O., Choi, Y.-D., Lee, S.-M., Cho, S. H., Kim, D. H., Kim, H.-S., & Jung, Y. D. (2024) · Figshare · doi:10.6084/m9.figshare.25770339
Kim, Y. S., Unno, T., Park, S.-Y., Chung, J. O., Choi, Y.-D., Lee, S.-M., Cho, S. H., Kim, D. H., Kim, H.-S., & Jung, Y. D. (2024) · Figshare · doi:10.6084/m9.figshare.26717400
Kim, Y. S., Unno, T., Park, S.-Y., Chung, J. O., Choi, Y.-D., Lee, S.-M., Cho, S. H., Kim, D. H., Kim, H.-S., & Jung, Y. D. (2024) · Figshare · doi:10.6084/m9.figshare.26717394
Introduction to postbiotics: Definition, mechanism of action, sources, and functionality
Kumari, S., Setpalani, K., Kelkar, S., Kumar, N., Kumari, V., & Dilip, S. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-33116-9.00001-2
Structural basis of bile acid lateral diffusion facilitated by the OSTα/β transporterPreprint
Hou, W.-T., Xu, K., Li, B.-R., Huang, G., Wang, F., Wang, J., Wang, B., Chu, C.-Y., Chen, G.-T., Zhou, C., et al. (2026) · Research Square · doi:10.21203/rs.3.rs-8254570/v1
Yuan, Z., He, S., & Zhang, X. (2026) · BMC Women s Health · doi:10.1186/s12905-026-04299-0
Lai, J., Zentek, J., & Grześkowiak, Ł. (2026) · Veterinary Sciences · doi:10.3390/vetsci13020209
Impact du microbiome intestinal sur la cholestérolémie : concepts et applications
Bourgin, M. (2021) · theses.fr (ABES) · doi:10.70675/5ef61a78z31c7z44fazafa1zd4a5749a4aaf
Jing, S., Lan, X., Liu, Y., Wang, J., Wang, Y., & Guo, N. (2026) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.5c15173
Mariaule, V. (2024) · theses.fr (ABES) · doi:10.70675/1d41e841zf788z4dd7z8784zc26304e24ea1
Metabolic machinery and pathways of the HMMS
Hou, Y. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-31402-5.00008-6
Zhang, W., Yin, T., Liu, X., Li, M., Wang, J., & Shi, B. (2026) · Food Bioscience · doi:10.1016/j.fbio.2026.108877
Wang, X., Jiang, Y., Feng, L., Luo, Y., Zhang, J., Wang, X., Wang, Y., Ma, Y., Hua, M., Jin, L., et al. (2026) · Phytomedicine · doi:10.1016/j.phymed.2026.158730
Liu, H., Feng, Z., Xu, H.-X., Zeng, H., Chen, X., Guo, Z.-H., Xiong, T., Zhang, X.-R., Liao, S., Zhao, H., et al. (2026) · Critical reviews in food science and nutrition · doi:10.1080/10408398.2026.2667409 · Cited by 1
From bile acids to yes-associated protein: A bidirectional switch for cholangiocarcinoma therapy
Zhang, S.-Y., Yu, H., Mi, Y., & Xiao, F. (2026) · World Journal of Gastrointestinal Oncology · doi:10.4251/wjgo.v18.i5.117990
The bile acid-gut microbiota-vitamin D axis: new insights into biliary atresia
Huang, C., Li, Z., Shen, W., Luo, M., & 林发全 (2026) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2026.1847110
Yin, Y., Li, C., Feng, Y., Bai, H., Pei, Z., Chen, Z., Zhang, Y. S., Li, C. J., Y, C., Deng, D., et al. (2026) · Veterinary Sciences · doi:10.3390/vetsci13060599
Ghaffari, M., Stoschus, A., Diesing, L. E., Schuchardt, S., & Hammon, H. M. (2026) · Journal of Dairy Science · doi:10.3168/jds.2026-28947
CHIMENE-WEISS, J. I., Bromfield, B. B., Feldman, T., Gheewalla, G., Mitten, E. K., Portincasa, P., & Baffy, G. (2026) · Advances in experimental medicine and biology · doi:10.1007/978-3-032-12166-0_4
Southwell, M., Faraco, M., Ruiz, M. J., Romanelli, A., & Sagües, M. F. (2026) · Domestic Animal Endocrinology · doi:10.1016/j.domaniend.2026.107044
Zhou, C., Xue, L., Song, M., Wang, R., Yuan, C., Zhang, H., Hu, X., & Sun, Y. (2026) · Frontiers in Pharmacology · doi:10.3389/fphar.2026.1890708
Lee, G. W., Song, H. Y., Kim, B. M., Hwang, I. Y., & Lee, J. W. (2026) · Current Opinion in Biotechnology · doi:10.1016/j.copbio.2026.103572
Gut-liver axis and intestinal microbiota: Key targets of herbal medicines in treatment of MASLD/MASH
Mao, Y., Wei, C., Zhang, Y., Zheng, Y., Ji, R., Ge, L. I. N., He, X., He, Y., Yang, J., & Ma, J. (2026) · Chinese Herbal Medicines · doi:10.1016/j.chmed.2026.08.017
Ali, Z., Rubab, M., Awad, W. A., Liebhart, D., Hess, M., & Arshad, N. (2026) · International Journal of Molecular Sciences · doi:10.3390/ijms27188132
Chang, S., Zha, Y., Chen, S., Xiao, Y., Zhou, Y., Tian, Y., Liu, Z., Zhang, X., Zhang, H., Li, W., et al. (2026) · Journal of Agricultural and Food Chemistry · doi:10.1021/acs.jafc.6c06885
Functional Food Microecology: An integrated strategy from gut modulation to systemic health
Sun, J., & Lun, Y. (2026) · MicroBiome and One Health · doi:10.1016/j.micoh.2026.100006
Pang, P. K. T., Yan, X., Long, X., Mi, J., Qin, C., Yang, L., & Nie, G. (2026) · Aquaculture Nutrition · doi:10.1155/anu/6145147
Zhang, W., Matuszek, G., Dolnikowski, G. G., Lamon‐Fava, S., Ausman, L. M., Lichtenstein, A. H., & Matthan, N. R. (2026) · American Journal of Clinical Nutrition · doi:10.1016/j.ajcnut.2026.101561
Su, Z., Han, L., Song, F., Wang, Y., & Lin, Y. (2026) · Current Microbiology · doi:10.1007/s00284-026-05189-2
Gut bacterial-derived beneficial proteins in intestinal disease
Zhou, S., Tian, Q., Ullah, S., Su, D., Geng, J., & Zhang, M. (2026) · Microbiological Research · doi:10.1016/j.micres.2026.128794
Adam, S. Y., Sayed, H., Ahmed, A. A., Osman, H. A., Abaker, A. O., Mohammed, L. A., Pan, S., Basher, A. A., Manyelo, T. G., Tyasi, T. L., et al. (2026) · Nutrition · doi:10.1016/j.nut.2026.113470
Metadata
- Authors
- Long, S. L., Gahan, C. G. M., & Joyce, S. A.
- Affiliations
- University College Cork (IE)
- Corresponding author
- Gahan, Cormac G.M.
- Venue
- Molecular Aspects of Medicine
- Publisher
- Elsevier BV
- Published
- 2017-08
- Volume
- 56
- Pages
- 54-65
- ISSN
- 0098-2997 (ISSN-L)
- OpenAlex
- W2626300127
- Cited by
- 495
- References
- 174
- Citations by year
- 2026: 42 · 2025: 52 · 2024: 67 · 2023: 56 · 2022: 82 · 2021: 69 · 2020: 47 · 2019: 38 · 2018: 31 · 2017: 10
- FWCI
- 3.23
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Molecular Aspects of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Funders
- APC Microbiome Institute (SFI/12/RC/2273)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Health Sciences › Medicine › Oncology › Drug Transport and Resistance Mechanisms
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Biochemistry › Cholesterol and Lipid Metabolism
- Keywords
- gut microbiota, bile acids, bile acid metabolism, bile salt hydrolase, deconjugation, dehydroxylation, secondary bile acids, bile acid homeostasis, farnesoid X receptor, TGR5, vitamin D receptor, Clostridium difficile infection, inflammatory bowel disease, gut-liver axis
- MeSH terms
- Gastrointestinal Microbiome, Receptor, Farnesoid X-Activated, Amidohydrolases, Animals, Bacterial Proteins, Bile Acids and Salts, Biotransformation, Enterocolitis, Pseudomembranous, Gene Expression Regulation, Homeostasis, Humans, Intestinal Mucosa, Intestines, Liver, NADH, NADPH Oxidoreductases, Clostridioides difficile, Receptors, Cytoplasmic and Nuclear, Receptors, Calcitriol, Receptors, G-Protein-Coupled, Host-Pathogen Interactions
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review