Cited by 96Probiotics and Fermented FoodsAntibiotic Use and ResistanceAntibiotic Resistance in Bacteria

Antibiotic susceptibility of probiotic strains: Is it reasonable to combine probiotics with antibiotics?

Neut, C., Mahieux, S., Dubreuil, L.J.·2017·Médecine et Maladies Infectieuses

Abstract

Objective The main goal of this study was to determine the in vitro susceptibility of strains collected from marketed probiotics to antibiotics used to treat community-acquired infections.Methods The minimum inhibitory concentrations (MICs) of 16 antibiotics were determined using a gradient strip (E test) or the agar dilution method for fidaxomicin.Results The probiotics demonstrated various antibiotic patterns. Bacterial probiotics are generally susceptible to most prescribed antibiotics orally administered, whereas yeast probiotics, such as Saccharomyces boulardii, are resistant.Conclusion Special attention must be paid to co-prescriptions of antibiotics and probiotics to ensure that the probiotic strain is not susceptible.

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Crossref · 10.1016/j.medmal.2017.07.001

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14 of 14 references verified0 citation errors · 0 not checkable

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Authors
Neut, C., Mahieux, S., & Dubreuil, L. J.
Affiliations
Inserm (FR)
Corresponding author
Dubreuil, L.J.
Venue
Médecine et Maladies Infectieuses
Publisher
Elsevier BV
Published
2017-11
Volume
47
Issue
7
Pages
477-483
ISSN
0399-077X (ISSN-L)
OpenAlex
W2745090517
Cited by
96
References
14
Citations by year
2026: 13 · 2025: 13 · 2024: 15 · 2023: 13 · 2022: 9 · 2021: 16 · 2020: 9 · 2019: 3 · 2018: 5
FWCI
5.23
Type
journal article
Language
en
Open access
closed
Locations
  • Médecine et Maladies Infectieuses (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Life Sciences › Immunology and Microbiology › Applied Microbiology and Biotechnology › Antibiotic Use and Resistance
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Antibiotic Resistance in Bacteria
Keywords
probiotics, antibiotic susceptibility, antibiotic resistance, community-acquired infections, minimum inhibitory concentration, fidaxomicin, Saccharomyces boulardii, probiotic bacteria
MeSH terms
Saccharomyces boulardii, Fidaxomicin, Aminoglycosides, Anti-Bacterial Agents, Bacillus, Bifidobacterium, Drug Resistance, Microbial, Lactobacillus, Microbial Sensitivity Tests, Probiotics, Drug Resistance, Fungal

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