Cited by 248Probiotics and Fermented FoodsReproductive tract infections researchGut microbiota and health

From yaks to yogurt: the history, development, and current use of probiotics

McFarland, L. V.·2015·Clinical Infectious Diseases

Abstract

The development of probiotics, which are living bacteria or yeasts used to confer a health benefit on the host, has paralleled our research in food preservation, microbiologic identification techniques, and our understanding of how the complex interactions in microbiota impact the host's health and recovery from disease. This review briefly describes the history of probiotics, where probiotic strains were originally isolated, and the types of probiotic products currently available on the global market. In addition, the uses or indications for these probiotics are described, along with the types of clinical investigations that have been done. Continuing challenges persist for the proper probiotic strain identification, regulatory pathways, and how healthcare providers can choose a specific strain to recommend to their patients.

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Crossref · 10.1093/cid/civ054

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Authors
McFarland, L. V.
Affiliations
University of Washington (US)
Corresponding author
McFarland, L. V.
Venue
Clinical Infectious Diseases
Published
2015-04-28
Volume
60
Issue
suppl 2
Pages
S85-S90
ISSN
  • 1058-4838 (ISSN-L)
  • 1537-6591
OpenAlex
W2051083422
Cited by
248
References
39
Citations by year
2026: 22 · 2025: 18 · 2024: 21 · 2023: 28 · 2022: 25 · 2021: 30 · 2020: 36 · 2019: 15 · 2018: 22 · 2017: 13 · 2016: 16 · 2015: 2
FWCI
2.20
Type
journal article
Language
en
Open access
closed
Locations
  • Clinical Infectious Diseases (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
  • Life Sciences › Immunology and Microbiology › Microbiology › Reproductive tract infections research
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
Keywords
probiotics, history of probiotics, probiotic products, probiotic regulation, gut microbiota, food preservation
MeSH terms
Animals, Anti-Bacterial Agents, Cattle, Diarrhea, Humans, Lactobacillus, Saccharomyces, Yogurt, Probiotics, Marketing

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