The DOI matches its Crossref record; 33 of the 33 references it cites were found in a registry or an index.
Effect of lifestyle intervention in patients with type 2 diabetes: A meta-analysis
Open accessAbstract
OBJECTIVE: The effect of lifestyle intervention on clinical risk factors in patients with type 2 diabetes is unclear. The aim of this meta-analysis was to evaluate the effects of comprehensive lifestyle change, such as diet, exercise, and education, on clinical markers that are risk-factors for cardiovascular disease in patients with type 2 diabetes. METHODS: We searched Medline, Cochrane, EMBASE, and Google Scholar (up to August 31, 2013) for randomized controlled trials that compared standard of care (control group) with treatment regimens that included changes in lifestyle (intervention group). The primary outcome was reduction in risk factors of cardiovascular disease including body mass index (BMI), glycated hemoglobin (HbA1c), systolic blood pressure (SBP), diastolic blood pressure (DBP), high-density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c). RESULTS: A total of 16 studies were included in the meta-analysis. The standardized difference in means of change from baseline significantly favored the intervention compared with the control group in BMI (-0.29; 95% CI, -0.52 to -0.06, P=0.014), HbA1c (-0.37; 95% CI, -0.59 to -0.14, P=0.001), SBP (-0.16: 95% CI, -0.29 to -0.03, P=0.016), DBP (-0.27, 95% CI=-0.41 to -0.12, P<0.001). There was no difference between the intervention and control groups in HDL-c (0.05; 95% CI, -0.10 to 0.21; P=0.503) and LDL-c (-0.14; 95% CI, -0.29 to 0.02; P=0.092). CONCLUSIONS: The meta-analysis found that lifestyle intervention showed significant benefit in risk factors that are known to be associated with development of cardiovascular disease in patients with type 2 diabetes.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“an increased animal fat (saturated fatty acid [SFA]) intake has been shown to be associated with the risk of diabetes 19 , 20 , 21 , 22 , 23 .”
From Japanese clinical practice guideline for diabetes 2019 (2020) · cites this paper as [19]
In the citing paper
“Thus, at present, DPP‐4 inhibitors appear to have a favorable safety profile 19 , 20 , 21 , 22 , while attention needs to be given to the potential onset of acute pancreatitis and bullous pemphigoid with these agents.”
From Japanese clinical practice guideline for diabetes 2019 (2020) · cites this paper as [19]
In the citing paper
“Diabetes is often associated with depressive symptoms and anxiety disorders specific to the disease 18 , 19 , 20 , leading to suboptimal self‐care, worsening of glycemic control, an increased risk of diabetic complications, and an impaired QOL, thus adversely affecting the prognosis of affected patients 21 , 22 .”
From Japanese clinical practice guideline for diabetes 2019 (2020) · cites this paper as [19]
In the citing paper
“There is a positive dose‐response relationship between qualitative markers of carbohydrate, i.e., glycemic index (GI) or glycemic load (GL), and the risk of type 2 diabetes 18 , 19 .”
From Japanese clinical practice guideline for diabetes 2019 (2020) · cites this paper as [19]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Standards of medical care in diabetes—2013
American Diabetes Association (2013) · Diabetes Care · doi:10.2337/dc13-s011 · Cited by 4,369
Heart Disease and Stroke Statistics—2009 Update
WRITING GROUP MEMBERS, Lloyd‐Jones, D. M., Adams, R. J., Carnethon, M. R., SIMONE, G. D., Ferguson, T. B., Flegal, K. M., Ford, E. S., Furie, K. L., Go, A. S., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.191259 · Cited by 3,915
WRITING GROUP MEMBERS, Lloyd-Jones, D., Adams, R., Carnethon, M., De Simone, G., Ferguson, T. B., Flegal, K., Ford, E., Furie, K., Go, A., et al. (2009) · Circulation · doi:10.1161/circulationaha.108.191261 · Cited by 3,140
Boulé, N. G., Haddad, E., Kenny, G. P., Wells, G. A., & Sigal, R. J. (2001) · JAMA · doi:10.1001/jama.286.10.1218 · Cited by 1,889
Epidemiology of Diabetes and Diabetes-Related Complications
Deshpande, A. D., Harris-Hayes, M., & Schootman, M. (2008) · Physical Therapy · doi:10.2522/ptj.20080020 · Cited by 1,773
(2010) · Archives of Internal Medicine · doi:10.1001/archinternmed.2010.334 · Cited by 1,162
Schellenberg, E. S., Dryden, D. M., Vandermeer, B., Ha, C., & Korownyk, C. (2013) · Annals of Internal Medicine · doi:10.7326/0003-4819-159-8-201310150-00007 · Cited by 520
Roizen, M. F. (2011) · Yearbook of Anesthesiology and Pain Management · doi:10.1016/j.yane.2011.01.029 · Cited by 487
Long-term non-pharmacological weight loss interventions for adults with type 2 diabetes mellitus
Norris, S. L., Zhang, X., Avenell, A., Gregg, E. W., Brown, T. J., Schmid, C. H., & Lau, J. (2005) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd004095.pub2 · Cited by 374
Yang, Z., Scott, C. A., Mao, C., Tang, J., & Farmer, A. J. (2014) · Sports Medicine · doi:10.1007/s40279-013-0128-8 · Cited by 346
Cited by
Sorted by citations
Physical activity/exercise and diabetes: A position statement of the American Diabetes Association
Colberg, S. R., Sigal, R. J., Yardley, J. E., Riddell, M. C., Dunstan, D. W., Dempsey, P. C., Horton, E. S., Castorino, K., & Tate, D. F. (2016) · Diabetes Care · doi:10.2337/dc16-1728 · Cited by 2,991
Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy
Jia, G., DeMarco, V. G., & Sowers, J. R. (2015) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2015.216 · Cited by 976
Epidemiology of Obesity and Diabetes and Their Cardiovascular Complications
Bhupathiraju, S. N., & Hu, F. B. (2016) · Circulation Research · doi:10.1161/circresaha.115.306825 · Cited by 1,000
Diabetes and hypertension: a position statement by the American Diabetes Association
de Boer, I. H., Bangalore, S., Benetos, A., Davis, A. M., Michos, E. D., Muntner, P., Rossing, P., Zoungas, S., & Bakris, G. (2017) · Diabetes Care · doi:10.2337/dci17-0026 · Cited by 714
Japanese clinical practice guideline for diabetes 2019
Araki, E., Goto, A., Kondo, T., Noda, M., Noto, H., Origasa, H., Osawa, H., Taguchi, A., Tanizawa, Y., Tobe, K., et al. (2020) · Diabetology International · doi:10.1007/s13340-020-00439-5 · Cited by 545
Metadata
- Authors
- Chen, L., Pei, J.-H., Kuang, J., Chen, H.-M., Chen, Z., Li, Z.-W., & Yang, H.-Z.
- Affiliations
- Guangdong General Hospital (CN)
- Corresponding author
- Chen, Liang
- Venue
- Metabolism
- Publisher
- Elsevier BV
- Published
- 2015-02
- Volume
- 64
- Issue
- 2
- Pages
- 338-347
- ISSN
- 0026-0495 (ISSN-L)
- OpenAlex
- W2085848038
- Cited by
- 343
- References
- 33
- Citations by year
- 2026: 12 · 2025: 33 · 2024: 28 · 2023: 24 · 2022: 39 · 2021: 43 · 2020: 42 · 2019: 37 · 2018: 26 · 2017: 22 · 2016: 19 · 2015: 17
- FWCI
- 3.13
- Type
- journal article
- Language
- en
- Open access
- hybrid
- doi.org
- Licence
- Locations
- Metabolism (publishedVersion, cc-by-nc-nd)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Treatment and Management
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Education
- Keywords
- type 2 diabetes, lifestyle intervention, cardiovascular risk factors, HbA1c, body mass index, blood pressure, HDL cholesterol, LDL cholesterol, diet, physical activity, diabetes education
- MeSH terms
- Cardiovascular Diseases, Combined Modality Therapy, Diabetes Mellitus, Type 2, Diabetic Angiopathies, Humans, Life Style, Risk Factors, Randomized Controlled Trials as Topic, Diabetic Cardiomyopathies
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
