The DOI matches its Crossref record; 83 of the 83 references it cites were found in a registry or an index.
Horizontal transfer of antibiotic resistance genes in the human gut microbiome
Open accessAbstract
Infections caused by antibiotic-resistant bacteria are a major threat to public health. The pathogens causing these infections can acquire antibiotic resistance genes in a process termed horizontal gene transfer (HGT). HGT is a common event in the human gut microbiome, that is, the microbial ecosystem of the human intestinal tract. HGT in the gut microbiome can occur via different mechanisms of which transduction and conjugation have been best characterised. Novel bioinformatic tools and experimental approaches have been developed to determine the association of antibiotic resistance genes with their microbial hosts and to quantify the extent of HGT in the gut microbiome. Insights from studies into HGT in the gut microbiome may lead to the development of novel interventions to minimise the spread of antibiotic resistance genes among commensals and opportunistic pathogens.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The text we found for this paper looks like another document, so the self-check wasn’t run.
Citations
Cites
Diversity of the Human Intestinal Microbial Flora
Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science · doi:10.1126/science.1110591 · Cited by 7,913
Human gut microbiome viewed across age and geography
Yatsunenko, T., Rey, F. E., Manary, M. J., Trehan, I., Dominguez-Bello, M. G., Contreras, M., Magris, M., Hidalgo, G., Baldassano, R. N., Anokhin, A. P., et al. (2012) · Nature · doi:10.1038/nature11053 · Cited by 7,815
CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes
Barrangou, R., Fremaux, C., Deveau, H., Richards, M., Boyaval, P., Moineau, S., Romero, D. A., & Horvath, P. (2007) · Science · doi:10.1126/science.1138140 · Cited by 5,947
Molecular mechanisms of antibiotic resistance
Blair, J. M. A., Webber, M. A., Baylay, A. J., Ogbolu, D. O., & Piddock, L. J. V. (2015) · Nature Reviews Microbiology · doi:10.1038/nrmicro3380 · Cited by 4,092
Cassini, A., Högberg, L. D., Plachouras, D., Quattrocchi, A., Hoxha, A., Simonsen, G. S., Colomb-Cotinat, M., Kretzschmar, M., Devleesschauwer, B., Cecchini, M., et al. (2018) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(18)30605-4 · Cited by 2,951
Shotgun metagenomics, from sampling to analysis
Quince, C., Walker, A. W., Simpson, J. T., Loman, N. J., & Segata, N. (2017) · Nature Biotechnology · doi:10.1038/nbt.3935 · Cited by 2,202
Dissemination of Antimicrobial Resistance in Microbial Ecosystems through Horizontal Gene Transfer
von Wintersdorff, C. J. H., Penders, J., van Niekerk, J. M., Mills, N. D., Majumder, S., van Alphen, L. B., Savelkoul, P. H. M., & Wolffs, P. F. G. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00173 · Cited by 1,707
The shared antibiotic resistome of soil bacteria and human pathogens
Forsberg, K. J., Reyes, A., Wang, B., Selleck, E. M., Sommer, M. O. A., & Dantas, G. (2012) · Science · doi:10.1126/science.1220761 · Cited by 1,650
What is a resistance gene? Ranking risk in resistomes
Martínez, J. L., Coque, T. M., & Baquero, F. (2014) · Nature Reviews Microbiology · doi:10.1038/nrmicro3399 · Cited by 1,033
The vocabulary of microbiome research: a proposal
Marchesi, J., & Ravel, J. (2015) · Microbiome · doi:10.1186/s40168-015-0094-5 · Cited by 1,016
Flagged first, then by citations
Cited by
Sorted by citations
Items 401–410 of 410
Pateriya, D., Tanwar, A., & Sharma, V. K. (2026) · Gut Pathogens · doi:10.1186/s13099-026-00860-2
A network dynamical simulation model for the study of antibiotic resistance in microbial communities
Silva-Magaña, M. A., Mora-Flores, L. P., Pita-Galeana, M. A., Lemus, E. H., & de Anda‐Jáuregui, G. (2026) · Gut Microbes · doi:10.1080/19490976.2026.2734703
dos Santos, N. P., Baptista, R. M., Kubelka, B. G., D’Oca, M. G. M., de Lima, J. T., Bueno, D. T., Leitzke, A. F., & Ramos, D. F. (2026) · Frontiers in Natural Products · doi:10.3389/fntpr.2026.1884549
Belhout, C., Freire, S., Aldeia, C., & Endimiani, A. (2026) · European Journal of Clinical Microbiology & Infectious Diseases · doi:10.1007/s10096-026-05674-3
Fabien, G., Habimana, E., Eric, R., Olive, D., Nkesiga, J., Dusabumuremyi, J. C., & Bahizi, M. (2026) · Research Square · doi:10.21203/rs.3.rs-10993593/v1
Kovenskiy, A., Mukhanbetzhanov, N., Jarmukhanov, Z., Duisebayeva, A., Morenko, M., Kossumov, A., Chulenbayeva, L., Vinogradova, E. B., Popov, M., Kushugulova, A. R., et al. (2026) · mSystems · doi:10.1128/msystems.00986-26
Wheeler, M., & Bakkeren, E. (2026) · Microbial Genomics · doi:10.1099/mgen.0.001856
Li, N., Ye, J., Wang, C., Zhu, C., & Li, H. (2026) · Microorganisms · doi:10.3390/microorganisms14102364
Tek Sağlık Perspektifinden Hayvan-İnsan Mikrobiyom Direnç Ağı: Mobil Rezistom Transferi
Aras, Ö. Ö. (2026) · Özgür Yayınları eBooks · doi:10.58830/ozgur.pub1508.c6072
Regulatory review and governance gaps for genetically engineered microbes
Kuzma, J., Cummings, C. L., & Grieger, K. (2026) · Frontiers in Genetics · doi:10.3389/fgene.2026.2008399
Metadata
- Authors
- McInnes, R. S., McCallum, G. E., Lamberte, L. E., & van Schaik, W.
- Affiliations
- University of Birmingham (GB)
- Corresponding author
- Lamberte, Lisa E
- Venue
- Current Opinion in Microbiology
- Publisher
- Elsevier BV
- Published
- 2020-02
- Volume
- 53
- Pages
- 35-43
- ISSN
- 1369-5274 (ISSN-L)
- OpenAlex
- W3009269518
- Cited by
- 401
- References
- 83
- Citations by year
- 2026: 49 · 2025: 90 · 2024: 79 · 2023: 69 · 2022: 59 · 2021: 41 · 2020: 14
- FWCI
- 3.37
- Type
- journal article
- Language
- en
- Open access
- Licence
- Locations
- Current Opinion in Microbiology (publishedVersion)
- PubMed (publishedVersion)
- University of Birmingham Research Portal (University of Birmingham) (submittedVersion, cc-by-nc-nd)
- Funders
- Biotechnology and Biological Sciences Research Council
- Wellcome Trust
- Royal Society
- Medical Research Council
- Topics
- Health Sciences › Medicine › Microbiology (medical) › Antibiotic Resistance in Bacteria
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Physical Sciences › Environmental Science › Pollution › Pharmaceutical and Antibiotic Environmental Impacts
- Keywords
- horizontal gene transfer, antibiotic resistance genes, human gut microbiome, transduction, conjugation, antibiotic resistance spread, commensal bacteria, opportunistic pathogens
- MeSH terms
- Gastrointestinal Microbiome, Animals, Anti-Bacterial Agents, Bacteria, Bacterial Proteins, Humans, Gene Transfer, Horizontal, Drug Resistance, Bacterial
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
