Cited by 247Marine Biology and Environmental ChemistryMicrobial Natural Products and BiosynthesisAquatic Ecosystems and Phytoplankton Dynamics

Antialgal, antibacterial and antifungal activity of two metabolites produced and excreted by cyanobacteria during growth

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Volk, Rainer-B., Furkert, Franz H.·2006·Microbiological Research

Abstract

The antimicrobial activity of two cyanobacterial exometabolites, norharmane (9H-pyrido(3,4-b)indole) and 4,4'-dihydroxybiphenyl, was determined in suspension assays. Good anticyanobacterial activities (concentrations of 8-80 microg ml(-1)) and moderate antibacterial (16-160 microg ml(-1)) and antifungal (32-40 microg ml(-1)) activities were found for both compounds. The natural function as allelopathic chemicals and a possible applicability as antifouling agents or leads for the development of new antifouling chemicals are discussed.

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Crossref · 10.1016/j.micres.2005.08.005

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  1. Wallha ¨ußer, K.H., 1995a. Chemische Konservierungsmit- tel gegen mikrobiellen Verderb. In: Wallha ¨ußer, K.H. (Ed.), Praxis der Sterilisation Desinfektion-Konservier- ung. Georg Thieme Verlag, Stuttgart, p. 437.
  2. Wallha ¨ußer, K.H., 1995b. Antimikrobielle Wirkstoffe. In: Wallha ¨ußer, K.H. (Ed.), Praxis der Sterilisation Desin- fektion-Konservierung. Georg Thieme Verlag, Stutt- gart, pp. 550-552.

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Authors
Volk, R.-B., & Furkert, F. H.
Affiliations
Christian-Albrechts-Universität zu Kiel (DE)
Corresponding author
Volk, Rainer-B.
Venue
Microbiological Research
Publisher
Elsevier BV
Published
2006-02
Volume
161
Issue
2
Pages
180-186
ISSN
0944-5013 (ISSN-L)
OpenAlex
W2002556492
Cited by
247
References
31
Citations by year
2026: 5 · 2025: 10 · 2024: 11 · 2023: 15 · 2022: 13 · 2021: 20 · 2020: 19 · 2019: 14 · 2018: 16 · 2017: 18 · 2016: 11 · 2015: 13 · 2014: 12 · 2013: 12 · 2012: 9
FWCI
19.08
Type
journal article
Language
en
Open access
Locations
  • Microbiological Research (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Engineering › Ocean Engineering › Marine Biology and Environmental Chemistry
  • Health Sciences › Medicine › Pharmacology › Microbial Natural Products and Biosynthesis
  • Physical Sciences › Environmental Science › Environmental Chemistry › Aquatic Ecosystems and Phytoplankton Dynamics
Keywords
norharman, 4,4'-biphenol, antialgal activity, antibacterial activity, antifungal activity, allelopathy, antifouling agents, natural products
MeSH terms
Cyanobacteria, Anti-Bacterial Agents, Antifungal Agents, Biphenyl Compounds, Carbolines, Harmine, Microbial Sensitivity Tests

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