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p53 Linear Diffusion along DNA Requires Its C Terminus
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“The CTD is required for rapid linear diffusion of p53 on DNA,27 mediating fast sliding to facilitate the search for cognate p53 binding sites.28”
From Mapping Interactions of the Intrinsically Disordered C-Terminal Regions of Tetrameric p53 by Segmental Isotope Labeling and NMR (2022) · cites this paper as [27]
In the citing paper
“Through its interactions with DNA, the CTD mediates binding of p53 to non-specific DNA sites, enables rapid diffusion on DNA to facilitate the search for cognate target sites, and enhances the specificity for specific p53 recognition elements.15,27,28,65-67”
From Mapping Interactions of the Intrinsically Disordered C-Terminal Regions of Tetrameric p53 by Segmental Isotope Labeling and NMR (2022) · cites this paper as [27]
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Cites
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The IARC TP53 database: new online mutation analysis and recommendations to users
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p53 Sites Acetylated In Vitro by PCAF and p300 Are Acetylated In Vivo in Response to DNA Damage
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Cited by
Blinded by the Light: The Growing Complexity of p53
Vousden, K. H., & Prives, C. (2009) · Cell · doi:10.1016/j.cell.2009.04.037 · Cited by 3,163
Self-citationRegulating the p53 pathway: in vitro hypotheses, in vivo veritas
Toledo, F., & Wahl, G. M. (2006) · Nature reviews. Cancer · doi:10.1038/nrc2012 · Cited by 1,286
The multiple mechanisms that regulate p53 activity and cell fate
Hafner, A., Bulyk, M. L., Jambhekar, A., & Lahav, G. (2019) · Nature Reviews Molecular Cell Biology · doi:10.1038/s41580-019-0110-x · Cited by 1,129
Principles of Protein−Protein Interactions: What are the Preferred Ways For Proteins To Interact?
Keskin, O., Gursoy, A., Ma, B., & Nussinov, R. (2008) · Chemical Reviews · doi:10.1021/cr040409x · Cited by 697
Transcriptional Regulation by P53
Beckerman, R., & Prives, C. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a000935 · Cited by 569
Self-citation
Metadata
- Authors
- McKinney, K., Mattia, M., Gottifredi, V., & Prives, C.
- Venue
- Molecular Cell
- Publisher
- Elsevier BV
- Published
- 2004-11
- Volume
- 16
- Issue
- 3
- Pages
- 413-424
- ISSN
- 1097-2765
- Cited by
- 174
- References
- 4
- Language
- en
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 3180 d)
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