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Complicating the complexity of p53

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p53 regulation by ubiquitin

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hCAS/CSE1L Associates with Chromatin and Regulates Expression of Select p53 Target Genes

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BBAP Monoubiquitylates Histone H4 at Lysine 91 and Selectively Modulates the DNA Damage Response

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Differential regulation of p53 and p21 by MKRN1 E3 ligase controls cell cycle arrest and apoptosis

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Yin Yang 1

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MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53

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Mitochondrial MDM2 Regulates Respiratory Complex I Activity Independently of p53

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E3 Ligases Determine Ubiquitination Site and Conjugate Type by Enforcing Specificity on E2 Enzymes

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Melatonin induces the apoptosis and inhibits the proliferation of human gastric cancer cells via blockade of the AKT/MDM2 pathway

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The Ubiquitin-Specific Protease USP7 Modulates the Replication of Kaposi's Sarcoma-Associated Herpesvirus Latent Episomal DNA

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Chromatin modifiers Mdm2 and RNF2 prevent RNA:DNA hybrids that impair DNA replication

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MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output

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Histone monoubiquitination by Clock-Bmal1 complex marks Per1 and Per2 genes for circadian feedback

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A Critical Role for Noncoding 5S rRNA in Regulating Mdmx Stability

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