Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping

Alternative isoform regulation in human tissue transcriptomes

Wang, E. T., Sandberg, R., Luo, S., Khrebtukova, I., Zhang, L., Mayr, C., Kingsmore, S. F., Schroth, G. P., & Burge, C. B. (2008) · Nature · doi:10.1038/nature07509 · Cited by 5,181

The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Christofk, H. R., Vander Heiden, M. G., Harris, M. H., Ramanathan, A., Gerszten, R. E., Wei, R., Fleming, M. D., Schreiber, S. L., & Cantley, L. C. (2008) · Nature · doi:10.1038/nature06734 · Cited by 2,820

Mechanisms of Alternative Pre-Messenger RNA Splicing

Black, D. L. (2003) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.72.121801.161720 · Cited by 2,704

The UCSC Genome Browser Database

Karolchik, D. (2003) · Nucleic Acids Research · doi:10.1093/nar/gkg129 · Cited by 1,890

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

Licatalosi, D. D., Mele, A., Fak, J. J., Ule, J., Kayikci, M., Chi, S. W., Clark, T. A., Schweitzer, A. C., Blume, J. E., Wang, X., et al. (2008) · Nature · doi:10.1038/nature07488 · Cited by 1,352 · cited 9×

Alternative pre-mRNA splicing and proteome expansion in metazoans

Maniatis, T., & Tasic, B. (2002) · Nature · doi:10.1038/418236a · Cited by 774

Systematic Identification and Analysis of Exonic Splicing Silencers

Wang, Z., Rolish, M. E., Yeo, G. W.-M., Tung, V., Mawson, M., & Burge, C. B. (2004) · Cell · doi:10.1016/j.cell.2004.11.010 · Cited by 678

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

Boutz, P. L., Stoilov, P., Li, Q., Lin, C.-H., Chawla, G., Ostrow, K., Shiue, L., Ares, M., & Black, D. L. (2007) · Genes & Development · doi:10.1101/gad.1558107 · Cited by 577

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells

Yeo, G. W., Coufal, N. G., Liang, T. Y., Peng, G. E., Fu, X.-D., & Gage, F. H. (2009) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1545 · Cited by 572

Distinct Binding Specificities and Functions of Higher Eukaryotic Polypyrimidine Tract-Binding Proteins

Singh, R., Valcárcel, J., & Green, M. R. (1995) · Science · doi:10.1126/science.7761834 · Cited by 539

The combinatorial control of alternative splicing in C. elegans

Tan, J. H., & Fraser, A. G. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1007033 · Cited by 18

Self-Attention Based Neural Network for Predicting RNA-Protein Binding Sites

Wang, X., Zhang, M., Long, C., Yao, L., & Zhu, M. (2022) · IEEE Transactions on Computational Biology and Bioinformatics · doi:10.1109/tcbb.2022.3204661 · Cited by 18

Arabidopsis PTB 1 and PTB 2 proteins negatively regulate splicing of a mini‐exon splicing reporter and affect alternative splicing of endogenous genes differentially

Simpson, C. G., Lewandowska, D., Liney, M., Davidson, D., Chapman, S. N., Fuller, J., McNicol, J., Shaw, P. D., & Brown, J. W. S. (2014) · New Phytologist · doi:10.1111/nph.12821 · Cited by 18

RNA Pol II inhibition activates cell death independently from the loss of transcription

Harper, N. W., Birdsall, G. A., Honeywell, M. E., Ward, K. M., Pai, A. A., & Lee, M. J. (2025) · Cell · doi:10.1016/j.cell.2025.07.034 · Cited by 18

All three RNA recognition motifs and the hinge region of HuC play distinct roles in the regulation of alternative splicing

Hinman, M. N., Zhou, H.-L., Sharma, A., & Lou, H. J. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt166 · Cited by 18

Computational challenges, tools, and resources for analyzing co‐ and post‐transcriptional events in high throughput

Bahrami‐Samani, E., Vo, D. T., Araujo, P. R. D., Vogel, C., Smith, A. D., Penalva, L. O. F., & Uren, P. J. (2014) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1274 · Cited by 15

Therapeutic Potential of PTB Inhibition Through Converting Glial Cells to Neurons in the Brain

Fu, X.-D., & Mobley, W. C. (2023) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-083022-113120 · Cited by 16

Solution and crystal structures of a C-terminal fragment of the neuronal isoform of the polypyrimidine tract binding protein (nPTB)

Joshi, A., Esteve, V., Buckroyd, A., Blatter, M., Allain, F. H. ‐., & Curry, S. (2014) · PeerJ · doi:10.7717/peerj.305 · Cited by 15

RNA-binding protein research with transcriptome-wide technologies in neural development

Yano, M., Ohtsuka, T., & Okano, H. (2014) · Cell and Tissue Research · doi:10.1007/s00441-014-1923-8 · Cited by 16

A developmentally regulated spliced variant of PTBP1 is upregulated in type 1 diabetic hearts

Belanger, K. K., Nutter, C. A., Li, J., Yu, P., & Kuyumcu‐Martinez, M. N. (2018) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2018.12.150 · Cited by 17

Hotspot exons are common targets of splicing perturbations

Glidden, D. T., Buerer, J. L., Saueressig, C. F., & Fairbrother, W. G. (2021) · Nature Communications · doi:10.1038/s41467-021-22780-2 · Cited by 16

Diverse regulation of 3′ splice site usage

Sohail, M., & Xie, J. (2015) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-015-2037-5 · Cited by 18

Deletion of AU-Rich Elements within the Bcl2 3′UTR Reduces Protein Expression and B Cell Survival In Vivo

Díaz‐Muñoz, M. D., Bell, S. E., & Turner, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0116899 · Cited by 17

Inflammatory Microenvironment Modulation of Alternative Splicing in Cancer: A Way to Adapt

Silva, A. L., Faria, M., & Matos, P. (2020) · Advances in experimental medicine and biology · doi:10.1007/978-3-030-34025-4_13 · Cited by 16

A comprehensive thermodynamic model for RNA binding by the Saccharomyces cerevisiae Pumilio protein PUF4

Sadée, C., Hagler, L. D., Becker, W. R., Jarmoskaite, I., Vaidyanathan, P. P., Denny, S. K., Greenleaf, W. J., & Herschlag, D. (2022) · Nature Communications · doi:10.1038/s41467-022-31968-z · Cited by 16

SRSF2 is required for mRNA splicing during spermatogenesis

Lei, W., Du, Z., Meng, T., Su, R., Li, Y., Liu, W., Sun, S., Liu, M., Hou, Y., Zhang, C., et al. (2023) · BMC Biology · doi:10.1186/s12915-023-01736-6 · Cited by 16

Direct reprogramming of terminally differentiated cells into neurons: A novel and promising strategy for Alzheimer's disease treatment

Yavarpour‐Bali, H., Ghasemi‐Kasman, M., & Shojaei, A. (2019) · Progress in Neuro-Psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2019.109820 · Cited by 15

PTBP1 mediates Sertoli cell actin cytoskeleton organization by regulating alternative splicing of actin regulators

Wang, Y., Chembazhi, U. V., Yee, D., Chen, S., Ji, J., Wang, Y., Nguyen, K. L., Lin, P.-C. P., Ratti, A., Hess, R. A., et al. (2024) · Nucleic Acids Research · doi:10.1093/nar/gkae862 · Cited by 14

Dissecting the expression relationships between RNA-binding proteins and their cognate targets in eukaryotic post-transcriptional regulatory networks

Nishtala, S., Neelamraju, Y., & Janga, S. C. (2016) · Scientific Reports · doi:10.1038/srep25711 · Cited by 14

RNA Processing: Redrawing the Map of Charted Territory

Corrionero, A., & Valcárcel, J. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.12.004 · Cited by 15

Multiple roles of RBM4 in muscle cell differentiation

Lin, J.-C. (2011) · Frontiers in Bioscience-Scholar · doi:10.2741/260 · Cited by 17

Biomarkers Identification in the Microenvironment of Oral Squamous Cell Carcinoma: A Systematic Review of Proteomic Studies

Pomella, S., Melaiu, O., Cifaldi, L., Bei, R., GARGARI, M., Campanella, V., & Barillari, G. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25168929 · Cited by 18

Assessing Computational Steps for CLIP-Seq Data Analysis

Liu, Q., Zhong, X. Y., Madison, B., Rustgi, A. K., & Shyr, Y. (2015) · BioMed Research International · doi:10.1155/2015/196082 · Cited by 13

Mathematical modeling identifies potential gene structure determinants of co-transcriptional control of alternative pre-mRNA splicing

Davis‐Turak, J., Johnson, T., & Hoffmann, A. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky870 · Cited by 13

The function and regulatory mechanism of RNA-binding proteins in breast cancer and their future clinical treatment prospects

Lu, X., Zhong, J., Liu, L., Zhang, W., Zhao, S., Chen, L., Wei, Y., Zhang, H., Wu, J., Chen, W., et al. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.929037 · Cited by 13

mRNA isoform balance in neuronal development and disease

LaForce, G. R., Philippidou, P., & Schaffer, A. E. (2022) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1762 · Cited by 15

Neural Differentiation Modulates the Vertebrate Brain Specific Splicing Program

Madgwick, A., Fort, P., Hanson, P. S., Thibault, P., Gaudreau, M., Lutfalla, G., Möröy, T., Elela, S. A., Chaudhry, B., Elliott, D. J., et al. (2015) · PLoS ONE · doi:10.1371/journal.pone.0125998 · Cited by 14

Decoding Abnormal Splicing Code in Human Diseases

Ohno, K. (2015) · Journal of Investigative Genomics · doi:10.15406/jig.2015.02.00016 · Cited by 12

Co-profiling of in situ RNA-protein interactions and transcriptome in single cells and tissues

Cheng, Q., Xie, G., Zhang, X., Wang, J., Ding, S., Wu, Y., Shi, M., Duan, F., Wan, Z.-L., Wei, J.-J., et al. (2025) · Nature Methods · doi:10.1038/s41592-025-02774-4 · Cited by 12

Post-transcriptional mechanisms controlling neurogenesis and direct neuronal reprogramming

Papadimitriou, E., & Thomaidou, D. (2023) · Neural Regeneration Research · doi:10.4103/1673-5374.390976 · Cited by 14

Promoter activity of polypyrimidine tract-binding protein genes of potato responds to environmental cues

Butler, N., & Hannapel, D. J. (2012) · Planta · doi:10.1007/s00425-012-1726-7 · Cited by 12

Statistical and Computational Methods for High-Throughput Sequencing Data Analysis of Alternative Splicing

Chen, L. (2012) · Statistics in Biosciences · doi:10.1007/s12561-012-9064-7 · Cited by 14

LncRNA ROR promotes NLRP3-mediated cardiomyocyte pyroptosis by upregulating FOXP1 via interactions with PTBP1

Min De, Z. E. N. G., Yi, S., Xiao, Y., & Chen, Z. (2022) · Cytokine · doi:10.1016/j.cyto.2022.155812 · Cited by 12

Rationally designed stapled peptides allosterically inhibit PTBP1–RNA-binding

Schmeing, S., Amrahova, G., Bigler, K., Chang, J., Openy, J., Pal, S., Posada, L., Gasper, R., & Hart, P. ‘. (2023) · Chemical Science · doi:10.1039/d3sc00985h · Cited by 12

Alternatively spliced MBNL1 isoforms exhibit differential influence on enhancing brown adipogenesis

Hung, C.-S., & Lin, J.-C. (2019) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2019.194437 · Cited by 12

Brain Repair by Cell Replacement via In Situ Neuronal Reprogramming

Qian, H., & Fu, X. (2021) · Annual Review of Genetics · doi:10.1146/annurev-genet-071719-023616 · Cited by 14

LncRNA HOXB-AS3 binding to PTBP1 protein regulates lipid metabolism by targeting SREBP1 in endometrioid carcinoma

Zhou, Q., Kong, D., Li, W., Shi, Z., Liu, Y., Sun, R., Ma, X., Qiu, C., Liu, Z., Hou, Y., et al. (2023) · Life Sciences · doi:10.1016/j.lfs.2023.121512 · Cited by 11

RNA structure, binding, and coordination in Arabidopsis

Foley, S. W., Kramer, M. C., & Gregory, B. D. (2017) · Wiley Interdisciplinary Reviews - RNA · doi:10.1002/wrna.1426 · Cited by 10

SMARTIV: combined sequence and structure de-novo motif discovery for in-vivo RNA binding data

Polishchuk, M. S., Paz, I., Yakhini, Z., & Mandel‐Gutfreund, Y. (2018) · Nucleic Acids Research · doi:10.1093/nar/gky453 · Cited by 11

Mapping of In Vivo RNA-Binding Sites by Ultraviolet (UV)-Cross-Linking Immunoprecipitation (CLIP)Preprint

Darnell, J. C., Mele, A., Hung, K. Y. S., & Darnell, R. B. (2018) · Cold Spring Harbor Protocols · doi:10.1101/pdb.top097931 · Cited by 12

Differential Gene Regulation of Lipid Synthesis in the Developing Seeds of Two Biodiesel Tree Species, Jatropha and Vernicia

Yangǂ, D., Huai-yun, Z., Peng, K., Chen, L., He, H., Huang, X., Qin, J., He, G., & Zhang, D. (2016) · International Journal of Agriculture and Biology · doi:10.17957/ijab/15.0218 · Cited by 11

RNA Secondary Structure Representation Network for RNA-proteins Binding Prediction

Liu, Z., Luo, F., & Du, B. (2021) · Proceedings of the AAAI Conference on Artificial Intelligence · doi:10.1609/aaai.v35i1.16112 · Cited by 10

A Posttranscriptional Mechanism That Controls Ptbp1 Abundance in the Xenopus Epidermis

Méreau, A., Anquetil, V., Lerivray, H., Viet, J., Schirmer, C., Audic, Y., Legagneux, V., Hardy, S., & Paillard, L. (2014) · Molecular and Cellular Biology · doi:10.1128/mcb.01040-14 · Cited by 9

Community effects in regulation of translation

Macdonald, P. M., Kanke, M., & Kenny, A. (2016) · eLife · doi:10.7554/elife.10965 · Cited by 9

HP1BP3 promotes tumor growth and metastasis by upregulating miR-23a to target TRAF5 in esophageal squamous cell carcinoma.

Shang, M., Weng, L., Wu, S., Liu, B., Yin, X., Wang, Z., & Mao, A. (2021) · PubMed Central · Cited by 9

Distinct and Modular Organization of Protein Interacting Sites in Long Non-coding RNAs

Jalali, S., Gandhi, S., & Scaria, V. (2018) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2018.00027 · Cited by 9

Research progress of cell treatment strategy in Parkinson's disease

Peng, Y., Chen, J., Hu, H., Liu, W., Liang, W., & Wang, J. (2024) · Neuroscience Applied · doi:10.1016/j.nsa.2024.104061 · Cited by 8

SOX2 interacts with hnRNPK to modulate alternative splicing in mouse embryonic stem cells

Huang, Y., Liu, Y., Pu, M., Zhang, Y., Cao, Q., Li, S., Wei, Y., & Hou, L. (2024) · Cell & Bioscience · doi:10.1186/s13578-024-01284-8 · Cited by 7

Polypyrimidine-Tract-Binding Protein Isoforms Differentially Regulate the Hepatitis C Virus Internal Ribosome Entry Site

Angulo, J., Cáceres, C. J., Contreras, N., Fernández-García, L., Chamond, N., Ameur, M., Sargueil, B., & López‐Lastra, M. (2022) · Viruses · doi:10.3390/v15010008 · Cited by 7

Unraveling the link between PTBP1 and severe asthma through machine learning and association rule mining method

Pirmoradi, S., Khatibi, S. M. H., Vahed, S. Z., Rad, H. H., Khamaneh, A. M., Akbarpour, Z., Seyedrezazadeh, E., Teshnehlab, M., Chapman, K. R., & Ansarin, K. (2023) · Scientific Reports · doi:10.1038/s41598-023-42581-5 · Cited by 7

The chloroplast RNA–binding protein CP29A supports rbcL expression during cold acclimation

Lenzen, B., Rösch, F., Legen, J., Ruwe, H., Kachariya, N. N., Sattler, M., Small, I., & Schmitz‐Linneweber, C. (2025) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2403969122 · Cited by 8

Transcriptome analysis reveals PTBP1 as a key regulator of circRNA biogenesis

Wang, M., Zheng, S., Zhang, Y., Zhang, J., Lai, F., Zhou, C., Zhou, Q., Li, X., & Li, G. (2025) · BMC Biology · doi:10.1186/s12915-025-02233-8 · Cited by 7

Alternative splicing regulation and its therapeutic potential in bladder cancer

Li, L., Jin, T., Hu, L., & Ding, J. (2024) · Frontiers in Oncology · doi:10.3389/fonc.2024.1402350 · Cited by 6

PTBP1 and Cancer: From RNA Regulation to Therapeutic Potential

Ji, C., Zhu, J., Hou, X., Zhou, C., Zhao, J., Zheng, X., & Tang, Y. (2025) · Journal of Cellular and Molecular Medicine · doi:10.1111/jcmm.70675 · Cited by 13

Structural insights reveal the specific recognition of meiRNA by the Mei2 protein

Shen, S., Jian, Y., Cai, Z., Li, F., Lv, M., Liu, Y., Wu, J., Fu, C., & Shi, Y. (2022) · Journal of Molecular Cell Biology · doi:10.1093/jmcb/mjac029 · Cited by 6

Cooperation and Competition of RNA Secondary Structure and RNA–Protein Interactions in the Regulation of Alternative Splicing

Vorobeva, M. A., Skvortsov, D. A., & Pervouchine, D. D. (2024) · Acta Naturae · doi:10.32607/actanaturae.26826 · Cited by 6

Zinc finger BED-type containing 3 promotes hepatic steatosis by interacting with polypyrimidine tract-binding protein 1

Wu, Y., Yang, M., Wu, S., Luo, P.-Q., Zhang, C., Ruan, C.-S., Cui, W., Zhao, Q.-R., Chen, L., Meng, J.-J., et al. (2024) · Diabetologia · doi:10.1007/s00125-024-06224-2 · Cited by 6

Unraveling the Mechanism of Action of Ubiquitin-Specific Protease 5 and Its Inhibitors in Tumors

Wang, J., Fang, S., Jiang, Y., & Hua, Q. (2024) · Clinical Medicine Insights Oncology · doi:10.1177/11795549241281932 · Cited by 6

Drosophila Polypyrimidine Tract-Binding Protein (DmPTB) Regulates Dorso-Ventral Patterning Genes in Embryos

Heimiller, J., Sridharan, V., Huntley, J., Wesley, C. S., & Singh, R. (2014) · PLoS ONE · doi:10.1371/journal.pone.0098585 · Cited by 6

Positioning of pyrimidine motifs around cassette exons defines their PTB ‐dependent splicing in Arabidopsis

Burgardt, R., Lambert, D., Heuwieser, C., Sack, M., Wagner, G., Weinberg, Z., & Wachter, A. (2024) · The Plant Journal · doi:10.1111/tpj.16739 · Cited by 5

Illuminating the Transcriptome through the Genome

Elliott, D. J. (2014) · Genes · doi:10.3390/genes5010235 · Cited by 7

Predicting Alternative Splicing

Barash, Y., & Vaquero-Garcia, J. (2014) · Methods in molecular biology · doi:10.1007/978-1-62703-980-2_28 · Cited by 6

Identification and Characterization of a Minimal Functional Splicing Regulatory Protein, PTBP1

Ontiveros, R. J., Hernandez, L. C., Nguyen, H., Lopez, A. L. H., Shankar, A., Kim, E., & Keppetipola, N. (2020) · Biochemistry · doi:10.1021/acs.biochem.0c00664 · Cited by 7

PTBP1 correlates with HER2 positivity, lymph node spread and metastasis in breast cancer

Tabatabaeian, S., Sadeghi, S., & Tabatabaeian, H. (2020) · Gene Reports · doi:10.1016/j.genrep.2020.100659 · Cited by 5

OCT4 translationally promotes AKT signaling as an RNA-binding protein in stressed pluripotent stem cells

Chen, W., Chen, X., Cheng, C., She, S., Li, X., Shan, L., Zhang, X., Dan, S., Wang, Y., Zhou, Y.-W., et al. (2025) · Stem Cell Research & Therapy · doi:10.1186/s13287-025-04229-1 · Cited by 7

Discovery of microRNA Regulatory Networks by Integrating Multidimensional High-Throughput Data

Yang, J., & Qu, L. (2012) · Advances in experimental medicine and biology · doi:10.1007/978-94-007-5590-1_13 · Cited by 5

A Novel Deep Learning Method for Predicting RNA-Protein Binding Sites

Zhao, X., Chang, F., Lv, H., Zou, G., & Zhang, B. (2023) · Applied Sciences · doi:10.3390/app13053247 · Cited by 5

Two Faces of Evil: Cancer and Neurodegeneration

Curran, T., & Christen, Y. (2010) · Research and perspectives in Alzheimer's disease · doi:10.1007/978-3-642-16602-0 · Cited by 5

A new method to identify global targets of RNA-binding proteins in plantsPreprint

Cheng, Y.-L., Hsieh, H., & Tu, S. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.06.11.448000 · Cited by 5

Re-Activation of Neurogenic Niches in Aging BrainPreprint

Maimon, R., Chillón-Marinas, C., Vazquez‐Sanchez, S., Kern, C., Jenie, I., Malukhina, K., Moore, S. R., Cui, J., Goginashvili, A., Moghadami, S., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.01.27.575940 · Cited by 6

CRIC-seq protocol for in situ profiling of proximal RNA-RNA contacts associated with RNA-binding proteins

Ye, R., Hu, N., & Xue, Y. (2023) · STAR Protocols · doi:10.1016/j.xpro.2023.102401 · Cited by 4

PTBP1-mediated repression of neuron-specific CDC42 splicing constitutes a genomic alteration-independent, developmentally conserved vulnerability in IDH-wildtype glioblastoma

Yang, J., Feng, J. H., Lv, J. G., Chu, X., Wei, Y., Zhang, Y., Li, J., Sun, Y., Li, G., Jiang, T., et al. (2024) · Functional & Integrative Genomics · doi:10.1007/s10142-024-01412-0 · Cited by 5

Recursive splicing is a rare event in the mouse brain

Moon, S., & Zhao, Y.-T. (2022) · PLoS ONE · doi:10.1371/journal.pone.0263082 · Cited by 4

PTBP1 enforces ATR-CHK1 signaling determining the potency of CDC7 inhibitors

Göder, A., Quinlan, A., Rainey, M. D., Bennett, D., Shamavu, D., Corso, J., & Santocanale, C. (2023) · iScience · doi:10.1016/j.isci.2023.106951 · Cited by 5

Therapeutic strategies for aberrant splicing in cancer and genetic disorders

Shi, W., Tang, J., & Xiang, J. (2024) · Clinical Genetics · doi:10.1111/cge.14478 · Cited by 4

An alternative simple method in laryngoscope blade decontamination.

Orhan, M. E., Saygun, O., & Güzeldemir, M. E. (2002) · PubMed · Cited by 4

The leader RNA of SARS-CoV-2 sequesters polypyrimidine tract binding protein (PTBP1) and influences pre-mRNA splicing in infected cells

Altina, N. H., Maranon, D. G., Anderson, J. R., Donaldson, M. K., Elmegerhi, S., Clair, L. A. S., Perera, R. M., Geiss, B. J., & Wilusz, J. (2024) · Virology · doi:10.1016/j.virol.2024.109986 · Cited by 3

RNA-protein interaction techniques - A historical and comparative analysis

Chakrabarty, S., Roy, S., Sarkar, S., & Singh, K. K. (2025) · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms · doi:10.1016/j.bbagrm.2025.195115 · Cited by 3

RBPMS and RBPMS2 Cooperate to Safeguard Cardiac Splicing

Wu, T., Chen, Z., Gao, C., Stanley, E. V., Zhang, Z., Gu, Y., Zhou, X., & Chen, J. (2025) · Circulation Research · doi:10.1161/circresaha.125.326948 · Cited by 3

A cutting-edge strategy for spinal cord injury treatment: resident cellular transdifferentiation

Fang, Y.-M., Chen, W.-C., Zheng, W.-J., Yang, Y.-S., Zhang, Y., Chen, X.-L., Pei, M.-Q., Lin, S., & He, H. (2023) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2023.1237641 · Cited by 3

PAIP1 binds to pre-mRNA and regulates alternative splicing of cancer pathway genes including VEGFA

Zheng, J., Zhang, X., Xue, Y., Shao, W., Wei, Y., Mi, S., Yang, X., Hu, L., Zhang, Y., & Ming, L. (2024) · BMC Genomics · doi:10.1186/s12864-024-10530-9 · Cited by 4

Splicing by cell type

Arias, M. A., Ke, S., & Chasin, L. A. (2010) · Nature Biotechnology · doi:10.1038/nbt0710-686 · Cited by 3

Effect of Diffuse Panbronchiolitis Critical Region 1 Polymorphisms on the Risk of Aspirin-Exacerbated Respiratory Disease in Korean Asthmatics

Lee, J. S., Bae, J. S., Kim, J., Kim, Y., Park, T. J., Pasaje, C. F. A., Park, B., Cheong, H. S., Uh, S., Park, J., et al. (2012) · Respiratory Care · doi:10.4187/respcare.01480 · Cited by 3

My road to alternative splicing control: from simple paths to loops and interconnections

Chabot, B. (2015) · Biochemistry and Cell Biology · doi:10.1139/bcb-2014-0161 · Cited by 3

hnRNP and hnRNP-Like Proteins in Splicing Control: Molecular Mechanisms and Implication in Human Pathologies

Lorkovic, Z. (2012) · CRC Press eBooks · doi:10.1201/9781498713368-7 · Cited by 3

Dissecting Splicing Regulatory Network by Integrative Analysis of CLIP-Seq Data

Zhang, M. Q. (2011) · Springer eBooks · doi:10.1007/978-1-4614-0782-9_12 · Cited by 2

A Quantitative Profiling Tool for Diverse Genomic Data Types Reveals Potential Associations between Chromatin and Pre-mRNA Processing

Kremsky, I., Bellora, N., & Eyras, E. (2015) · PLoS ONE · doi:10.1371/journal.pone.0132448 · Cited by 3

Analysis of Protein–RNA Interactions with Single‐Nucleotide Resolution Using iCLIP and Next‐Generation Sequencing

König, J., McGlincy, N. J., & Ule, J. (2011) · Wiley eBooks · doi:10.1002/9783527644582.ch10 · Cited by 3

Large-Scale Immunopurification of Ribonucleoprotein Complexes from Drosophila Nucleoplasmic Extracts for Tiling MicroarraysPreprint

Rio, D. C. (2014) · Cold Spring Harbor Protocols · doi:10.1101/pdb.prot080705 · Cited by 3

Data Science Issues in Understanding Protein-RNA InteractionsPreprint

Chakrabarti, A. M., Haberman, N., Praznik, A., Luscombe, N. M., & Ule, J. (2017) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/208124 · Cited by 3

Molecular Consequences of a Missense PHF21A Variant, c.1285G > A, Associated With Syndromic Neurodevelopmental Disorder

Gavilan, C. M., Murata-Nakamura, Y., Porter, R. S., Cutler, B., Rai, S., Kim, H., & Iwase, S. (2025) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-025-01584-8 · Cited by 2

Genetic variation within ABCE1 is associated with the chicken L blood system

Fulton, J. E., McCarron, A. M., Wolc, A., Mullen, A., Foerstner, C., Sparling, B. A. T. E., Drobik-Czwarno, W., & Taylor, R. L. (2025) · Poultry Science · doi:10.1016/j.psj.2025.106027 · Cited by 2

KIS counteracts PTBP2 and regulates alternative exon usage in neurons

Moreno-Aguilera, M., Mendoza, M. B., Neher, A. M., Dodel, M., Mardakheh, F. K., Ortiz, R., & Gallego, C. (2024) · eLife · doi:10.7554/elife.96048 · Cited by 1

Profiling genetically driven alternative splicing across the Indonesian archipelago

Ibeh, N., Kusuma, P., Darusallam, C. C., Malik, S. G., Sudoyo, H., McCarthy, D. J., & Romero, I. G. (2024) · The American Journal of Human Genetics · doi:10.1016/j.ajhg.2024.09.004 · Cited by 2

Activation of the intronic cryptic 5′ splice site depends on its distance to the upstream cassette exon

Liu, W., Li, X., Liao, S., Dou, K., & Zhang, Y. (2017) · Gene · doi:10.1016/j.gene.2017.03.023 · Cited by 2

Mammalian Cis-Acting RNA Sequence Elements

Louis, I. V.-S., & Sagarsky, C. (2018) · InTech eBooks · doi:10.5772/intechopen.72124 · Cited by 3

Alternative Splice Site Selection

Coelho, M. B., & Smith, C. W. J. (2012) · Wiley eBooks · doi:10.1002/9783527636778.ch8 · Cited by 2

Investigating Alternative Splicing and Polyadenylation of the Interleukin 7 Receptor (IL7R) Exon 6: Implications for Multiple Sclerosis

Evsyukova, I. Y. (2012) · Cited by 2

The function and regulation of the U11-48K protein in U12-dependent splicing

Turunen, J. J. (2012) · Työväentutkimus Vuosikirja · Cited by 2

Neuron-specific repression of alternative splicing by the conserved CELF protein UNC-75 in Caenorhabditis elegans

Pilaka, P. P., Sadek, N. H., Fusca, D. D., Cutter, A. D., & Calarco, J. A. (2025) · Genetics · doi:10.1093/genetics/iyaf025 · Cited by 2

Position-dependent alternative splicing activity revealed by global profiling of alternative splicing events regulated by PTB

Llorian, M., Schwartz, S., Clark, T. A., Hollander, D., Tan, L.-Y., Spellman, R., Gordon, A., Schweitzer, A. C., de la Grange, P., Ast, G., et al. (2010) · Nature Structural & Molecular Biology · doi:10.1038/nsmb.1881 · Cited by 263

Exon repression by polypyrimidine tract binding protein

Amir-Ahmady, B., Boutz, P. L., Markovtsov, V. V., Phillips, M. L., & Black, D. L. (2005) · RNA · doi:10.1261/rna.2250405 · Cited by 118

Exon repression by polypyrimidine tract binding protein. RNA

Amir-Ahmady, B., Boutz, P. L., Markovtsov, V. V., Phillips, M. L., Black, D. L., & Hughes, H. (2005)

Regulation of alternative splicing by PTB and associated factors

Spellman, R., Rideau, A., Matlin, A., Gooding, C., Robinson, F., McGlincy, N., Grellscheid, S. N., Southby, J., Wollerton, M., & Smith, C. W. J. (2005) · Biochemical Society Transactions · doi:10.1042/bst0330457 · Cited by 128

Novel modes of splicing repression by PTB

Spellman, R., & Smith, C. W. J. (2006) · Trends in Biochemical Sciences · doi:10.1016/j.tibs.2005.12.003 · Cited by 160