Mechanisms of Alternative Pre-Messenger RNA Splicing

Identification of Novel Genes Coding for Small Expressed RNAs

Lagos-Quintana, M., Rauhut, R., Lendeckel, W., & Tuschl, T. (2001) · Science · doi:10.1126/science.1064921 · Cited by 4,956 · see citing works

An Abundant Class of Tiny RNAs with Probable Regulatory Roles in <i>Caenorhabditis elegans</i>

Lau, N. C., Lim, L. P., Weinstein, E. G., & Bartel, D. P. (2001) · Science · doi:10.1126/science.1065062 · Cited by 2,713 · see citing works

Listening to silence and understanding nonsense: exonic mutations that affect splicing

Cartegni, L., Chew, S. L., & Krainer, A. R. (2002) · Nature Reviews Genetics · doi:10.1038/nrg775 · Cited by 2,209 · see citing works

microRNAs

Ambros, V. (2001) · Cell · doi:10.1016/s0092-8674(01)00616-x · Cited by 1,704 · see citing works

A genomic view of alternative splicing

Modrek, B., & Lee, C. (2002) · Nature Genetics · doi:10.1038/ng0102-13 · Cited by 1,307 · see citing works

RNA-Binding Proteins Tia-1 and Tiar Link the Phosphorylation of Eif-2α to the Assembly of Mammalian Stress Granules

Kedersha, N., Gupta, M., Li, W., Miller, I. J., & Anderson, P. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.147.7.1431 · Cited by 1,260 · see citing works

Alternative splicing: increasing diversity in the proteomic world

Graveley, B. R. (2001) · Trends in Genetics · doi:10.1016/s0168-9525(00)02176-4 · Cited by 1,228 · see citing works

An extensive network of coupling among gene expression machines

Maniatis, T., & Reed, R. (2002) · Nature · doi:10.1038/416499a · Cited by 1,148 · see citing works

Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things

Staley, J. P., & Guthrie, C. (1998) · Cell · doi:10.1016/s0092-8674(00)80925-3 · Cited by 1,127 · see citing works

Microarray identification of FMRP-associated brain mRNAs and altered mRNA translational profiles in fragile X syndrome

Brown, V., Jin, P., Ceman, S., Darnell, J. C., O'Donnell, W. T., Tenenbaum, S. A., Jin, X., Feng, Y., Wilkinson, K. D., Keene, J. D., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00568-2 · Cited by 1,109 · see citing works

Drosophila Dscam Is an Axon Guidance Receptor Exhibiting Extraordinary Molecular Diversity

Schmucker, D., Clemens, J. C., Shu, H., Worby, C. A., Xiao, J. Y., Muda, M., Dixon, J. E., & Zipursky, S. L. (2000) · Cell · doi:10.1016/s0092-8674(00)80878-8 · Cited by 1,105 · see citing works

Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcriptionPreprint

Komarnitsky, P. B., Cho, E., & Buratowski, S. (2000) · Genes & Development · doi:10.1101/gad.824700 · Cited by 1,098 · see citing works

Exon Recognition in Vertebrate Splicing

Berget, S. M. (1995) · Journal of Biological Chemistry · doi:10.1074/jbc.270.6.2411 · Cited by 1,090 · see citing works

Integrating mRNA Processing with Transcription

Proudfoot, N. J., Furger, A., & Dye, M. J. (2002) · Cell · doi:10.1016/s0092-8674(02)00617-7 · Cited by 1,084 · see citing works

Sorting out the complexity of SR protein functions

Graveley, B. R. (2000) · RNA · doi:10.1017/s1355838200000960 · Cited by 1,080 · see citing works

Predictive Identification of Exonic Splicing Enhancers in Human Genes

Fairbrother, W. G., Yeh, R., Sharp, P. A., & Burge, C. B. (2002) · Science · doi:10.1126/science.1073774 · Cited by 1,020 · see citing works

The spliceosome deposits multiple proteins 20–24 nucleotides upstream of mRNA exon–exon junctions

Hir, H. L., Izaurralde, E., Maquat, L. E., & Moore, M. J. (2000) · The EMBO Journal · doi:10.1093/emboj/19.24.6860 · Cited by 970 · see citing works

Large-Scale Proteomic Analysis of the Human SpliceosomePreprint

Rappsilber, J., Ryder, U., Lamond, A. I., & Mann, M. (2002) · Genome Research · doi:10.1101/gr.473902 · Cited by 945 · see citing works

The C-terminal domain of RNA polymerase II couples mRNA processing to transcription

McCracken, S. A., Fong, N., Yankulov, K., Ballantyne, S. M., Pan, G., Greenblatt, J., Patterson, S. D., Wickens, M., & Bentley, D. L. (1997) · Nature · doi:10.1038/385357a0 · Cited by 925 · see citing works

Alternative pre-mRNA splicing: the logic of combinatorial control

Smith, C. W. J., & Valcárcel, J. (2000) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01604-2 · Cited by 901 · see citing works

miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs

Mourelatos, Z., Dostie, J., Paushkin, S., Sharma, A., Charroux, B., Abel, L., Rappsilber, J., Mann, M., & Dreyfuss, G. (2002) · Genes &amp; Development · doi:10.1101/gad.974702 · Cited by 886 · see citing works

Comprehensive proteomic analysis of the human spliceosome

Zhou, Z., Licklider, L. J., Gygi, S. P., & Reed, R. (2002) · Nature · doi:10.1038/nature01031 · Cited by 884 · see citing works

AU Binding Proteins Recruit the Exosome to Degrade ARE-Containing mRNAs

Chen, C.-Y., Gherzi, R., Ong, S.-E., Chan, E. L., Raijmakers, R., Pruijn, G. J. M., Stoecklin, G., Moroni, C., Mann, M., & Karin, M. (2001) · Cell · doi:10.1016/s0092-8674(01)00578-5 · Cited by 865 · see citing works

The exon–exon junction complex provides a binding platform for factors involved in mRNA export and nonsense‐mediated mRNA decay

Hir, H. L., Gatfield, D., Izaurralde, E., & Moore, M. J. (2001) · The EMBO Journal · doi:10.1093/emboj/20.17.4987 · Cited by 842 · see citing works

hnRNP complexes: composition, structure, and function

Krecic, A. M., & Swanson, M. S. (1999) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(99)80051-9 · Cited by 813 · see citing works

SR proteins: a conserved family of pre-mRNA splicing factors.Preprint

Zahler, A. M., Lane, W. S., Stolk, J. A., & Roth, M. (1992) · Genes & Development · doi:10.1101/gad.6.5.837 · Cited by 798 · see citing works

Aberrant regulation of insulin receptor alternative splicing is associated with insulin resistance in myotonic dystrophy

Savkur, R. S., Philips, A. V., & Cooper, T. A. (2001) · Nature Genetics · doi:10.1038/ng704 · Cited by 795 · see citing works

Mechanism and regulation of mRNA polyadenylation

Colgan, D. F., & Manley, J. L. (1997) · Genes &amp; Development · doi:10.1101/gad.11.21.2755 · Cited by 784 · see citing works

Specific interactions between proteins implicated in splice site selection and regulated alternative splicing

Wu, J. Y., & Maniatis, T. (1993) · Cell · doi:10.1016/0092-8674(93)90316-i · Cited by 755 · see citing works

Regulation of alternative pre-mRNA splicing by hnRNP A1 and splicing factor SF2

Mayeda, A., & Krainer, A. R. (1992) · Cell · doi:10.1016/0092-8674(92)90477-t · Cited by 735 · see citing works

Disruption of an SF2/ASF-dependent exonic splicing enhancer in SMN2 causes spinal muscular atrophy in the absence of SMN1

Cartegni, L., & Krainer, A. R. (2002) · Nature Genetics · doi:10.1038/ng854 · Cited by 730 · see citing works

THE HIV-1 REV PROTEIN

Pollard, V. W., & Malim, M. H. (1998) · Annual Review of Microbiology · doi:10.1146/annurev.micro.52.1.491 · Cited by 715 · see citing works

Exon definition may facilitate splice site selection in RNAs with multiple exons.

Robberson, B. L., Cote, G. J., & Berget, S. M. (1990) · Molecular and Cellular Biology · doi:10.1128/mcb.10.1.84 · Cited by 710 · see citing works

Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases

Blencowe, B. J. (2000) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(00)01549-8 · Cited by 687 · see citing works

SR proteins and splicing control.Preprint

Manley, J. L., & Tacke, R. (1996) · Genes & Development · doi:10.1101/gad.10.13.1569 · Cited by 673 · see citing works

Alternative splicing: multiple control mechanisms and involvement in human disease

Cáceres, J. F., & Kornblihtt, A. R. (2002) · Trends in Genetics · doi:10.1016/s0168-9525(01)02626-9 · Cited by 654 · see citing works

ALTERNATIVE SPLICING OF PRE-mRNA: Developmental Consequences and Mechanisms of Regulation

Lopez, A. J. (1998) · Annual Review of Genetics · doi:10.1146/annurev.genet.32.1.279 · Cited by 644 · see citing works

Protein–protein interactions and 5'-splice-site recognition in mammalian mRNA precursors

Kohtz, J. D., Jamison, S. F., Will, C. L., et al. (1994) · Nature · doi:10.1038/368119a0 · Cited by 626 · see citing works

Regulation of Alternative Splicing in Vivo by Overexpression of Antagonistic Splicing Factors

Cáceres, J. F., Stamm, S., Helfman, D. M., & Krainer, A. R. (1994) · Science · doi:10.1126/science.8085156 · Cited by 619 · see citing works

Loss of the Muscle-Specific Chloride Channel in Type 1 Myotonic Dystrophy Due to Misregulated Alternative Splicing

Charlet‐Berguerand, N., Savkur, R. S., Singh, G., Philips, A. V., Grice, E. A., & Cooper, T. A. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00572-5 · Cited by 619 · see citing works

The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution.

Colwill, K., Pawson, T. J., Andrews, B., Prasad, J., Manley, J. L., Bell, J. C., & Duncan, P. I. (1996) · The EMBO Journal · doi:10.1002/j.1460-2075.1996.tb00357.x · Cited by 583 · see citing works

RNA polymerase II and the integration of nuclear eventsPreprint

Hirose, Y., & Manley, J. L. (2000) · Genes & Development · doi:10.1101/gad.14.12.1415 · Cited by 575 · see citing works

Protein Diversity from Alternative Splicing

Black, D. L. (2000) · Cell · doi:10.1016/s0092-8674(00)00128-8 · Cited by 565 · see citing works

TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus

Grüter, P., Tabernero, C., von Kobbe, C., Schmitt, C., Saavedra, C., Bachi, A., Wilm, M., Felber, B. K., & Izaurralde, E. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80065-9 · Cited by 560 · see citing works

A serine kinase regulates intracellular localization of splicing factors in the cell cycle

Gui, J., Lane, W. S., & Fu, X. (1994) · Nature · doi:10.1038/369678a0 · Cited by 543 · see citing works

Distinct Binding Specificities and Functions of Higher Eukaryotic Polypyrimidine Tract-Binding Proteins

Singh, R., Valcárcel, J., & Green, M. R. (1995) · Science · doi:10.1126/science.7761834 · Cited by 539 · see citing works

Control of Male Sexual Behavior and Sexual Orientation in Drosophila by the fruitless Gene

Ryner, L. C., Goodwin, S. F., Castrillón, D. H., Anand, A., Villella, A., Baker, B. S., Hall, J. C., Taylor, B. J., & Wasserman, S. A. (1996) · Cell · doi:10.1016/s0092-8674(00)81802-4 · Cited by 524 · see citing works

Identification of functional exonic splicing enhancer motifs recognized by individual SR proteinsPreprint

Liu, H., Zhang, M. Q., & Krainer, A. R. (1998) · Genes & Development · doi:10.1101/gad.12.13.1998 · Cited by 513 · see citing works

Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing

Larsson, S., Charlieu, J.-P., Miyagawa, K., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90392-5 · Cited by 510 · see citing works

RNA binding specificity of hnRNP A1: significance of hnRNP A1 high‐affinity binding sites in pre‐mRNA splicing.

Burd, C. G., & Dreyfuss, G. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06369.x · Cited by 488 · see citing works

Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex

Neubauer, G., King, A., Rappsilber, J., Calvio, C., Watson, M. A., Ajuh, P., Sleeman, J., Lamond, A. I., & Mann, M. (1998) · Nature Genetics · doi:10.1038/1700 · Cited by 478 · see citing works

Sex in flies: the splice of life

Baker, B. S. (1989) · Nature · doi:10.1038/340521a0 · Cited by 468 · see citing works

Identification of a (CUG)n Triplet Repeat RNA-Binding Protein and Its Expression in Myotonic Dystrophy

Timchenko, L., Miller, J. W., Timchenko, N. A., DeVore, D. R., Datar, K. V., Lin, L., Roberts, R., Caskey, C. T., & Swanson, M. S. (1996) · Nucleic Acids Research · doi:10.1093/nar/24.22.4407 · Cited by 465 · see citing works

The CELF Family of RNA Binding Proteins Is Implicated in Cell-Specific and Developmentally Regulated Alternative Splicing

Ladd, A. N., Charlet‐Berguerand, N., & Cooper, T. A. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.4.1285-1296.2001 · Cited by 449 · see citing works

A functional interaction between the histone deacetylase Rpd3 and the corepressor Groucho in Drosophila developmentPreprint

Chen, G., Fernandez, J., Mische, S. M., & Courey, A. J. (1999) · Genes & Development · doi:10.1101/gad.13.17.2218 · Cited by 444 · see citing works

Experimental annotation of the human genome using microarray technology

Shoemaker, D. D., Schadt, E. E., Armour, C. D., He, Y. D., Garrett-Engele, P. W., MCDONAGH, P. D., Loerch, P., Leonardson, A. S., Lum, P. Y., Cavet, G., et al. (2001) · Nature · doi:10.1038/35057141 · Cited by 440 · see citing works

Nova-1 Regulates Neuron-Specific Alternative Splicing and Is Essential for Neuronal Viability

Jensen, K. B., Dredge, B. K., Stefani, G., Zhong, R., Buckanovich, R. J., Okano, H. J., Yang, Y. Y. L., & Darnell, R. B. (2000) · Neuron · doi:10.1016/s0896-6273(00)80900-9 · Cited by 426 · see citing works

Genomewide Analysis of mRNA Processing in Yeast Using Splicing-Specific Microarrays

Clark, T. A., Sugnet, C. W., & Ares, M. (2002) · Science · doi:10.1126/science.1069415 · Cited by 411 · see citing works

Pre-mRNA splicing and mRNA export linked by direct interactions between UAP56 and Aly

Luo, M., Zhou, Z., Magni, K., Christoforides, C., Rappsilber, J., Mann, M., & Reed, R. (2001) · Nature · doi:10.1038/35098106 · Cited by 403 · see citing works

A Conserved mRNA Export Machinery Coupled to pre-mRNA Splicing

Reed, R., & Hurt, E. (2002) · Cell · doi:10.1016/s0092-8674(02)00627-x · Cited by 400 · see citing works

Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing.Preprint

Xiao, S.-H., & Manley, J. L. (1997) · Genes & Development · doi:10.1101/gad.11.3.334 · Cited by 397 · see citing works

Exon Identity Established through Differential Antagonism between Exonic Splicing Silencer-Bound hnRNP A1 and Enhancer-Bound SR Proteins

Zhu, J., Mayeda, A., & Krainer, A. R. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00409-9 · Cited by 396 · see citing works

Direct Coupling of Transcription and mRNA Processing through the Thermogenic Coactivator PGC-1

Monsalve, M., Wu, Z., Adelmant, G., Puigserver, P., Fan, M., & Spiegelman, B. M. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00031-9 · Cited by 395 · see citing works

Splicing is required for rapid and efficient mRNA export in metazoans

Luo, M., & Reed, R. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.26.14937 · Cited by 379 · see citing works

Polypyrimidine Tract Binding Protein Antagonizes Exon Definition

Wagner, E. J., & García-Blanco, M. A. (2001) · Molecular and Cellular Biology · doi:10.1128/mcb.21.10.3281-3288.2001 · Cited by 376 · see citing works

The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities.

Tacke, R., & Manley, J. L. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07360.x · Cited by 373 · see citing works

Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein

Handa, N., Nureki, O., Kurimoto, K., Kim, I., Sakamoto, H., Shimura, Y., Muto, Y., & Yokoyama, S. (1999) · Nature · doi:10.1038/19242 · Cited by 372 · see citing works

Allosteric Cascade of Spliceosome Activation

Brow, D. A. (2002) · Annual Review of Genetics · doi:10.1146/annurev.genet.36.043002.091635 · Cited by 372 · see citing works

Binding of the Drosophila Sex-lethal gene product to the alternative splice site of transformer primary transcript

Inoue, K., Hoshijima, K., Sakamoto, H., et al. (1990) · Nature · doi:10.1038/344461a0 · Cited by 352 · see citing works

Structure, function and evolution of sex-determining systems in Dipteran insects

Schütt, C., & Nöthiger, R. (2000) · Development · doi:10.1242/dev.127.4.667 · Cited by 352 · see citing works

Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns.Preprint

García-Blanco, M. A., Jamison, S. F., & Sharp, P. A. (1989) · Genes & Development · doi:10.1101/gad.3.12a.1874 · Cited by 346 · see citing works

A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA

Tian, M., & Maniatis, T. (1993) · Cell · doi:10.1016/0092-8674(93)90298-5 · Cited by 345 · see citing works

The Mkk3/6-p38–Signaling Cascade Alters the Subcellular Distribution of Hnrnp A1 and Modulates Alternative Splicing Regulation

van Oordt, C. W. M. D. H., Díaz-Meco, M. T., Lozano, J., Krainer, A. R., Moscat, J., & Cáceres, J. F. (2000) · The Journal of Cell Biology · doi:10.1083/jcb.149.2.307 · Cited by 345 · see citing works

Stimulatory effect of splicing factors on transcriptional elongation

Fong, Y. W., & Zhou, Q. (2001) · Nature · doi:10.1038/414929a · Cited by 341 · see citing works

Differential SMN2 expression associated with SMA severity

Gavrilov, D. K., Shi, X., Das, K., Gilliam, T. C., & Wang, C. H. (1998) · Nature Genetics · doi:10.1038/3030 · Cited by 337 · see citing works

Pre-mRNA splicing alters mRNP composition: evidence for stable association of proteins at exon–exon junctionsPreprint

Hir, H. L., Moore, M. J., & Maquat, L. E. (2000) · Genes & Development · doi:10.1101/gad.14.9.1098 · Cited by 337 · see citing works

Characterization and molecular cloning of polypyrimidine tract-binding protein: a component of a complex necessary for pre-mRNA splicing.Preprint

Patton, J. G., Mayer, S. A., Tempst, P., & Nadal‐Ginard, B. (1991) · Genes & Development · doi:10.1101/gad.5.7.1237 · Cited by 334 · see citing works

Alternative RNA splicing in the nervous system

Grabowski, P. J., & Black, D. L. (2001) · Progress in Neurobiology · doi:10.1016/s0301-0082(01)00007-7 · Cited by 331 · see citing works

A new regulatory protein, KSRP, mediates exon inclusion through an intronic splicing enhancer.Preprint

Min, H., Turck, C. W., Nikolic, J. M., & Black, D. L. (1997) · Genes & Development · doi:10.1101/gad.11.8.1023 · Cited by 330 · see citing works

Regulation of mammalian spliceosome assembly by a protein phosphorylation mechanism.

Mermoud, J. E., Cohen, P. T., & Lamond, A. I. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06906.x · Cited by 330 · see citing works

Function of conserved domains of hnRNP A1 and other hnRNP A/B proteins.

Mayeda, A., Munroe, S. H., Cáceres, J. F., & Krainer, A. R. (1994) · The EMBO Journal · doi:10.1002/j.1460-2075.1994.tb06883.x · Cited by 329 · see citing works

Regulated tissue-specific expression of antagonistic pre-mRNA splicing factors.

Hanamura, A., Cáceres, J. F., Mayeda, A., Franza, B. R., & Krainer, A. R. (1998) · PubMed Central · Cited by 329 · see citing works

Expression of Msl-2 causes assembly of dosage compensation regulators on the X chromosomes and female lethality in Drosophila

Kelley, R. L., Solovyeva, I., Lyman, L. M., et al. (1995) · Cell · doi:10.1016/0092-8674(95)90007-1 · Cited by 326 · see citing works

RNA Polymerase II Targets Pre-mRNA Splicing Factors to Transcription Sites In Vivo

Misteli, T., & Spector, D. L. (1999) · Molecular Cell · doi:10.1016/s1097-2765(01)80002-2 · Cited by 326 · see citing works

A sequence-specific, single-strand binding protein activates the far upstream element of c-myc and defines a new DNA-binding motif.Preprint

DUNCAN, R. C., Bazar, L. S., Michelotti, G. A., Tomonaga, T., Krutzsch, H. C., Avigan, M., & Levens, D. (1994) · Genes & Development · doi:10.1101/gad.8.4.465 · Cited by 326 · see citing works

SRPK2: A Differentially Expressed SR Protein-specific Kinase Involved in Mediating the Interaction and Localization of Pre-mRNA Splicing Factors in Mammalian Cells

Wang, H., Lin, W., Dyck, J. A., Yeakley, J. M., Songyang, Z., Cantley, L. C., & Fu, X. (1998) · The Journal of Cell Biology · doi:10.1083/jcb.140.4.737 · Cited by 324 · see citing works

Crystal structure of the two-RRM domain of hnRNP A1 (UP1) complexed with single-stranded telomeric DNAPreprint

Ding, J., Hayashi, M. K., Zhang, Y., Manche, L., Krainer, A. R., & Xu, R.-M. (1999) · Genes & Development · doi:10.1101/gad.13.9.1102 · Cited by 322 · see citing works

Nova, the paraneoplastic Ri antigen, is homologous to an RNA-binding protein and is specifically expressed in the developing motor system

Buckanovich, R. J., Posner, J. B., & Darnell, R. B. (1993) · Neuron · doi:10.1016/0896-6273(93)90077-5 · Cited by 318 · see citing works

Cooperative Assembly of an hnRNP Complex Induced by a Tissue-Specific Homolog of Polypyrimidine Tract Binding Protein

Markovtsov, V. V., Nikolic, J. M., Goldman, J. A., Turck, C. W., Chou, M., & Black, D. L. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.20.7463-7479.2000 · Cited by 311 · see citing works

hnRNP 1, the polyprimidine tract-binding protein: distinct nuclear localization and association with hnRNAs

Ghetti, A., Piñol-Roma, S., Michael, W. M., Morandi, C., & Dreyfuss, G. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.14.3671 · Cited by 311 · see citing works

Coupling of Transcription with Alternative Splicing

Cramer, P., Cáceres, J. F., Cazalla, D., Kadener, S., Muro, A. F., Baralle, F. E., & Kornblihtt, A. R. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80372-x · Cited by 310 · see citing works

The protein Sex-lethal antagonizes the splicing factor U2AF to regulate alternative splicing of transformer pre-mRNA

Valcárcel, J., Singh, R., Zamore, P. D., & Green, M. R. (1993) · Nature · doi:10.1038/362171a0 · Cited by 309 · see citing works

A splicing enhancer in the human fibronectin alternate ED1 exon interacts with SR proteins and stimulates U2 snRNP binding.Preprint

Lavigueur, A., Branche, H. L., Kornblihtt, A. R., et al. (1993) · Genes & Development · doi:10.1101/gad.7.12a.2405 · Cited by 307 · see citing works

RNA RECOGNITION BY RNP PROTEINS DURING RNA PROCESSING

Varani, G., & Nagai, K. (1998) · Annual Review of Biophysics and Biomolecular Structure · doi:10.1146/annurev.biophys.27.1.407 · Cited by 306 · see citing works

Neuronal pp60 c- src Contains a Six-Amino Acid Insertion Relative to Its Non-Neuronal Counterpart

Martinez, R., Mathey-Prévôt, B., Bernards, A., & Baltimore, D. (1987) · Science · doi:10.1126/science.2440106 · Cited by 305 · see citing works

A single cardiac troponin T gene generates embryonic and adult isoforms via developmentally regulated alternate splicing.

Cooper, T. A., & Ordahl, C. P. (1985) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(17)39158-5 · Cited by 304 · see citing works

Sex-specific alternative splicing of RNA from the transformer gene results from sequence-dependent splice site blockage

Sosnowski, B. A., Belote, J. M., & McKeown, M. (1989) · Cell · doi:10.1016/0092-8674(89)90426-1 · Cited by 292 · see citing works

Inhibition of msl-2 splicing by Sex-lethal reveals interaction between U2AF35 and the 3′ splice site AG

Merendino, L., Guth, S., Bilbao, D., Martínez, C., & Valcárcel, J. (1999) · Nature · doi:10.1038/45602 · Cited by 290 · see citing works

The Apoptosis-Promoting Factor TIA-1 Is a Regulator of Alternative Pre-mRNA Splicing

Förch, P., Puig, Ó., Kedersha, N., et al. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)00107-6 · Cited by 289 · see citing works

The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing.Preprint

Zuo, P., & Maniatis, T. (1996) · Genes & Development · doi:10.1101/gad.10.11.1356 · Cited by 287 · see citing works

Telomere elongation by hnRNP A1 and a derivative that interacts with telomeric repeats and telomerase

Branche, H. L., Dupuis, S., Ben‐David, Y., Bani, M. R., Wellinger, R. J., & Chabot, B. (1998) · Nature Genetics · doi:10.1038/575 · Cited by 280 · see citing works

Effects of RNA secondary structure on alternative splicing of Pre-mRNA: Is folding limited to a region behind the transcribing RNA polymerase?

Eperon, L. P., Graham, I. R., Griffiths, A. D., & Eperon, I. C. (1988) · Cell · doi:10.1016/0092-8674(88)90202-4 · Cited by 275 · see citing works

Composition and Functional Characterization of the Yeast Spliceosomal Penta-snRNP

Stevens, S. W., Ryan, D. E., Ge, H. Y., Moore, R. E., Young, M. K., Lee, T. D., & Abelson, J. N. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00436-7 · Cited by 273 · see citing works

The Regulation of Splice-Site Selection, and Its Role in Human Disease

Cooper, T. A., & Mattox, W. (1997) · The American Journal of Human Genetics · doi:10.1086/514856 · Cited by 272 · see citing works

Protein functions in pre-mRNA splicing

Will, C. L., & Lührmann, R. (1997) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(97)80003-8 · Cited by 271 · see citing works

Inhibition by SR proteins of splicing of a regulated adenovirus pre-mRNA

Kanopka, A., Mühlemann, O., & Akusjärvi, G. (1996) · Nature · doi:10.1038/381535a0 · Cited by 265 · see citing works

The mRNA assembly line: transcription and processing machines in the same factory

Bentley, D. L. (2002) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(02)00333-2 · Cited by 261 · see citing works

Sex lethal controls dosage compensation in Drosophila by a non-splicing mechanism

Kelley, R. L., Wang, J., Bell, L. R., & Kuroda, M. I. (1997) · Nature · doi:10.1038/387195a0 · Cited by 260 · see citing works

The Neuronal RNA Binding Protein Nova-1 Recognizes Specific RNA Targets In Vitro and In Vivo

Buckanovich, R. J., & Darnell, R. B. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.6.3194 · Cited by 259 · see citing works

hnRNP A/B proteins are required for inhibition of HIV‐1 pre‐mRNA splicing

Caputi, M., Mayeda, A., Krainer, A. R., & Zahler, A. M. (1999) · The EMBO Journal · doi:10.1093/emboj/18.14.4060 · Cited by 258 · see citing works

hnRNP H Is a Component of a Splicing Enhancer Complex That Activates a c- src Alternative Exon in Neuronal Cells

Chou, M., Rooke, N., Turck, C. W., & Black, D. L. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.69 · Cited by 251 · see citing works

Crystal Structure of a Pumilio Homology Domain

Wang, X., Zamore, P. D., & Hall, T. M. T. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00229-5 · Cited by 248 · see citing works

Characterization of cDNAs encoding the polypyrimidine tract-binding protein.Preprint

Gil, A., Sharp, P. A., Jamison, S. F., & García-Blanco, M. A. (1991) · Genes & Development · doi:10.1101/gad.5.7.1224 · Cited by 248 · see citing works

A CaMK IV responsive RNA element mediates depolarization-induced alternative splicing of ion channels

Xie, J., & Black, D. L. (2001) · Nature · doi:10.1038/35073593 · Cited by 248 · see citing works

Alternatively Spliced Isoforms of Nerve- and Muscle-Derived Agrin

Burgess, R. W., Nguyen, Q. T., Son, Y., Lichtman, J. W., & Sanes, J. R. (1999) · Neuron · doi:10.1016/s0896-6273(00)80751-5 · Cited by 247 · see citing works

WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomesPreprint

Davies, R. C., Calvio, C., Bratt, E., Larsson, S., Lamond, A. I., & Hastie, N. D. (1998) · Genes & Development · doi:10.1101/gad.12.20.3217 · Cited by 246 · see citing works

Modulation of exon skipping and inclusion by heterogeneous nuclear ribonucleoprotein A1 and pre-mRNA splicing factor SF2/ASF.

Mayeda, A., Helfman, D. M., & Krainer, A. R. (1993) · Molecular and Cellular Biology · doi:10.1128/mcb.13.5.2993 · Cited by 242 · see citing works

Phosphorylated RNA polymerase II stimulates pre-mRNA splicingPreprint

Hirose, Y., Tacke, R., & Manley, J. L. (1999) · Genes & Development · doi:10.1101/gad.13.10.1234 · Cited by 241 · see citing works

A Xenopus Protein Related to hnRNP I Has a Role in Cytoplasmic RNA Localization

Cote, C. A., Gautreau, D., Denegre, J. M., Kress, T. L., Terry, N. A., & Mowry, K. L. (1999) · Molecular Cell · doi:10.1016/s1097-2765(00)80345-7 · Cited by 240 · see citing works

The constitutive transport element (CTE) of Mason-Pfizer monkey virus (MPMV) accesses a cellular mRNA export pathway

Pasquinelli, A. E., Ernst, R. K., Lund, E., Grimm, C., Zapp, M. L., Rekosh, D., Hammarskjöld, M., & Dahlberg, J. E. (1997) · The EMBO Journal · doi:10.1093/emboj/16.24.7500 · Cited by 239 · see citing works

Identification of a New Class of Exonic Splicing Enhancers by In Vivo Selection

Coulter, L. R., Landree, M. A., & Cooper, T. A. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.4.2143 · Cited by 238 · see citing works

Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer.Preprint

Lynch, K. W., & Maniatis, T. (1996) · Genes & Development · doi:10.1101/gad.10.16.2089 · Cited by 238 · see citing works

Capping, splicing, and 3′ processing are independently stimulated by RNA polymerase II: different functions for different segments of the CTDPreprint

Fong, N., & Bentley, D. L. (2001) · Genes & Development · doi:10.1101/gad.889101 · Cited by 237 · see citing works

Modulation of DNA Binding Specificity by Alternative Splicing of the Wilms Tumor wt1 Gene Transcript

Bickmore, W. A., Oghene, K., Little, M. H., et al. (1992) · Science · doi:10.1126/science.1321494 · Cited by 235 · see citing works

The Protein Kinase Clk/Sty Directly Modulates SR Protein Activity: Both Hyper- and Hypophosphorylation Inhibit Splicing

Prasad, J., Colwill, K., Pawson, T. J., & Manley, J. L. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.10.6991 · Cited by 235 · see citing works

Mutation of PTB binding sites causes misregulation of alternative 3' splice site selection in vivo.

Pérez, I. C., Lin, C.-H., McAfee, J. G., & Patton, J. G. (1997) · PubMed Central · Cited by 235 · see citing works

Mutually exclusive splicing of α-tropomyosin exons enforced by an unusual lariat branch point location: Implications for constitutive splicing

Smith, C. W. J., & Nadal-Ginard, B. (1989) · Cell · doi:10.1016/0092-8674(89)90678-8 · Cited by 230 · see citing works

A brain-enriched polypyrimidine tract-binding protein antagonizes the ability of Nova to regulate neuron-specific alternative splicing

Polydorides, A. D., Okano, H. J., Yang, Y. Y. L., Stefani, G., & Darnell, R. B. (2000) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.110128397 · Cited by 230 · see citing works

Coupling RNA polymerase II transcription with pre-mRNA processing

Bentley, D. L. (1999) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(99)80048-9 · Cited by 228 · see citing works

Determinants of SR protein specificity

Tacke, R., & Manley, J. L. (1999) · Current Opinion in Cell Biology · doi:10.1016/s0955-0674(99)80050-7 · Cited by 226 · see citing works

U1 snRNP targets an essential splicing factor, U2AF65, to the 3' splice site by a network of interactions spanning the exon.Preprint

Hoffman, B. E., & Grabowski, P. J. (1992) · Genes & Development · doi:10.1101/gad.6.12b.2554 · Cited by 226 · see citing works

Regulation of adenovirus alternative RNA splicing by dephosphorylation of SR proteins

Kanopka, A., Mühlemann, O., Petersen‐Mahrt, S. K., Nilsson, C. E., Öhrmalm, C., & Akusjärvi, G. (1998) · Nature · doi:10.1038/30277 · Cited by 224 · see citing works

Oncoprotein TLS Interacts with Serine-Arginine Proteins Involved in RNA Splicing

Yang, L., Embree, L. J., Tsai, S., & Hickstein, D. D. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.43.27761 · Cited by 224 · see citing works

Splicing regulation as a potential genetic modifier

Nissim‐Rafinia, M., & Kerem, B. (2002) · Trends in Genetics · doi:10.1016/s0168-9525(01)02619-1 · Cited by 224 · see citing works

hnRNP A1 Recruited to an Exon In Vivo Can Function as an Exon Splicing Silencer

Gatto–Konczak, F. D., Olive, M., Gesnel, M.-C., & Breathnach, R. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.251 · Cited by 224 · see citing works

Selection of splice sites in pre-mRNAs with short internal exons.

Dominski, Z., & Kole, R. (1991) · Molecular and Cellular Biology · doi:10.1128/mcb.11.12.6075 · Cited by 223 · see citing works

A coactivator of pre-mRNA splicingPreprint

Blencowe, B. J., Issner, R., Nickerson, J. A., et al. (1998) · Genes & Development · doi:10.1101/gad.12.7.996 · Cited by 221 · see citing works

A neuron-specific splicing switch mediated by an array of pre-mRNA repressor sites: evidence of a regulatory role for the polypyrimidine tract binding protein and a brain-specific PTB counterpart.

Ashiya, M., & Grabowski, P. J. (1997) · PubMed · Cited by 220 · see citing works

The neuronal RNA-binding protein Nova-2 is implicated as the autoantigen targeted in POMA patients with dementia

Yang, Y. Y. L., Yin, G. L., & Darnell, R. B. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.22.13254 · Cited by 219 · see citing works

Ser/Thr-specific protein phosphatases are required for both catalytic steps of pre-mRNA splicing

Mermoud, J. E., Cohen, P., & Lamond, A. I. (1992) · Nucleic Acids Research · doi:10.1093/nar/20.20.5263 · Cited by 218 · see citing works

Arginine/Serine-Rich Domains of SR Proteins Can Function as Activators of Pre-mRNA Splicing

Graveley, B. R., & Maniatis, T. (1998) · Molecular Cell · doi:10.1016/s1097-2765(00)80076-3 · Cited by 217 · see citing works

The Polypyrimidine Tract Binding Protein Binds Upstream of Neural Cell-Specific c- src Exon N1 To Repress the Splicing of the Intron Downstream

Chan, R. C., & Black, D. L. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.8.4667 · Cited by 216 · see citing works

Molecular basis of sequence‐specific recognition of pre‐ribosomal RNA by nucleolin

Allain, F. H. ‐., Bouvet, P., Dieckmann, T., & Feigon, J. F. (2000) · The EMBO Journal · doi:10.1093/emboj/19.24.6870 · Cited by 214 · see citing works

The Regulation of the Drosophila Gene Reveals a Function for in Translational Control

Bashaw, G. J., & Baker, B. S. (1997) · Cell · doi:10.1016/s0092-8674(00)80262-7 · Cited by 212 · see citing works

Profiling alternative splicing on fiber-optic arrays

Yeakley, J. M., Fan, J., Doucet, D., Luo, L., Wickham‐Garcia, E., Ye, Z., Chee, M. S., & Fu, X. (2002) · Nature Biotechnology · doi:10.1038/nbt0402-353 · Cited by 207 · see citing works

Determination of the RNA Binding Specificity of the Heterogeneous Nuclear Ribonucleoprotein (hnRNP) H/H′/F/2H9 Family

Caputi, M., & Zahler, A. M. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.m102861200 · Cited by 206 · see citing works

Modulation of exon skipping by high‐affinity hnRNP A1‐binding sites and by intron elements that repress splice site utilization

Blanchette, M., & Chabot, B. (1999) · The EMBO Journal · doi:10.1093/emboj/18.7.1939 · Cited by 205 · see citing works

The SR Protein SRp38 Represses Splicing in M Phase Cells

Shin, C., & Manley, J. L. (2002) · Cell · doi:10.1016/s0092-8674(02)01038-3 · Cited by 204 · see citing works

Purification and characterization of a kinase specific for the serine- and arginine-rich pre-mRNA splicing factors.

Gui, J., Tronchère, H., Chandler, S. D., et al. (1994) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.91.23.10824 · Cited by 203 · see citing works

Post-transcriptional regulation: The dawn of PTB

Valcárcel, J., & Gebauer, F. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00361-7 · Cited by 201 · see citing works

The RNA-Binding Protein TIA-1 Is a Novel Mammalian Splicing Regulator Acting through Intron Sequences Adjacent to a 5′ Splice Site

Gatto–Konczak, F. D., Bourgeois, C. F., Guiner, C. L., Kister, L., Gesnel, M.-C., Stévenin, J., & Breathnach, R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.17.6287-6299.2000 · Cited by 200 · see citing works

Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability.Preprint

Wang, J., Takagaki, Y., & Manley, J. L. (1996) · Genes & Development · doi:10.1101/gad.10.20.2588 · Cited by 200 · see citing works

Positive Control of Pre-mRNA Splicing in Vitro

Tian, M., & Maniatis, T. (1992) · Science · doi:10.1126/science.1566072 · Cited by 200 · see citing works

Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: Creation of an SRp40-specific splicing enhancer

Tacke, R., Chen, Y., & Manley, J. L. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.4.1148 · Cited by 200 · see citing works

The Splicing Factor, Prp40, Binds the Phosphorylated Carboxyl-terminal Domain of RNA Polymerase II

Morris, D. P., & Greenleaf, A. L. (2000) · Journal of Biological Chemistry · doi:10.1074/jbc.m004118200 · Cited by 198 · see citing works

Functional Association of U2 snRNP with the ATP-Independent Spliceosomal Complex E

Das, R., Zhou, Z., & Reed, R. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80318-4 · Cited by 198 · see citing works

Function of quaking in myelination: Regulation of alternative splicing

Wu, J. I., Reed, R., Grabowski, P. J., & Artzt, K. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.072090399 · Cited by 198 · see citing works

Multiple Distinct Splicing Enhancers in the Protein-Coding Sequences of a Constitutively Spliced Pre-mRNA

Schaal, T. D., & Maniatis, T. (1999) · Molecular and Cellular Biology · doi:10.1128/mcb.19.1.261 · Cited by 198 · see citing works

Multisite RNA Binding and Release of Polypyrimidine Tract Binding Protein during the Regulation of c-src Neural-Specific Splicing

Chou, M., Underwood, J. G., Nikolic, J. M., Luu, M. H. T., & Black, D. L. (2000) · Molecular Cell · doi:10.1016/s1097-2765(00)80260-9 · Cited by 198 · see citing works

Co-transcriptional commitment to alternative splice site selection

Roberts, G. P. (1998) · Nucleic Acids Research · doi:10.1093/nar/26.24.5568 · Cited by 198 · see citing works

The generally expressed hnRNP F is involved in a neural-specific pre-mRNA splicing event.Preprint

Min, H., Chan, R. C., & Black, D. L. (1995) · Genes & Development · doi:10.1101/gad.9.21.2659 · Cited by 197 · see citing works

The RNA binding protein YB‐1 binds A/C‐rich exon enhancers and stimulates splicing of the CD44 alternative exon v4

Stickeler, E., Fraser, S. D., Honig, A., Chen, A. L., Berget, S. M., & Cooper, T. A. (2001) · The EMBO Journal · doi:10.1093/emboj/20.14.3821 · Cited by 196 · see citing works

RNP particles at splice junction sequences on Drosophila chorion transcripts

Yn, O. (1985) · Cell · doi:10.1016/0092-8674(85)90019-4 · Cited by 195 · see citing works

Phosphorylation–dephosphorylation differentially affects activities of splicing factor ASF/SF2

Xiao, S.-H., & Manley, J. L. (1998) · The EMBO Journal · doi:10.1093/emboj/17.21.6359 · Cited by 195 · see citing works

Signals and their transduction pathways regulating alternative splicing: a new dimension of the human genome

Stamm, S. (2002) · Human Molecular Genetics · doi:10.1093/hmg/11.20.2409 · Cited by 193 · see citing works

Sex-specific transcriptional regulation by the male and female doublesex proteins of Drosophila.Preprint

Coschigano, K. T., & Wensink, P. C. (1993) · Genes & Development · doi:10.1101/gad.7.1.42 · Cited by 191 · see citing works

Dynamic Antagonism between ETR-3 and PTB Regulates Cell Type-Specific Alternative Splicing

Charlet‐Berguerand, N., Singh, G., Cooper, T. A., & Logan, P. (2002) · Molecular Cell · doi:10.1016/s1097-2765(02)00479-3 · Cited by 190 · see citing works

Finding splice sites within a wilderness of RNA.

Black, D. L. (1995) · PubMed · Cited by 187 · see citing works

Functional domains of the human splicing factor ASF/SF2.

Zuo, P., & Manley, J. L. (1993) · The EMBO Journal · doi:10.1002/j.1460-2075.1993.tb06161.x · Cited by 186 · see citing works

Regulation of Sex-Specific Selection of fruitless 5′ Splice Sites by transformer and transformer-2

Heinrichs, V., Ryner, L. C., & Baker, B. S. (1998) · Molecular and Cellular Biology · doi:10.1128/mcb.18.1.450 · Cited by 185 · see citing works

Regulation of alternative pre‐mRNA splicing by the ERK MAP‐kinase pathway

Weg‐Remers, S., Ponta, H., Herrlich, P., & König, H. (2001) · The EMBO Journal · doi:10.1093/emboj/20.15.4194 · Cited by 184 · see citing works

Regulation of transcription factor localization: fine-tuning of gene expression

Vandromme, M., Gauthier‐Rouvière, C., Lamb, N. J. C., et al. (1996) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(96)80182-4 · Cited by 183 · see citing works

ELAV, a Drosophila neuron-specific protein, mediates the generation of an alternatively spliced neural protein isoform

Koushika, S. P., Lisbin, M. J., & White, K. (1996) · Current Biology · doi:10.1016/s0960-9822(02)70787-2 · Cited by 181 · see citing works

A Subset of SR Proteins Activates Splicing of the Cardiac Troponin T Alternative Exon by Direct Interactions with an Exonic Enhancer

Ramchatesingh, J., Zahler, A. M., Neugebauer, K. M., Roth, M. B., & Cooper, T. A. (1995) · Molecular and Cellular Biology · doi:10.1128/mcb.15.9.4898 · Cited by 179 · see citing works

Male‐specific lethal 2, a dosage compensation gene of Drosophila, undergoes sex‐specific regulation and encodes a protein with a RING finger and a metallothionein‐like cysteine cluster.

Zhou, S., Yang, Y., Scott, M. J., Pannuti, A., Fehr, K. C., Eisen, A., Koonin, E. V., Fouts, D. L., Wrightsman, R. A., & Manning, J. E. (1995) · The EMBO Journal · doi:10.1002/j.1460-2075.1995.tb07288.x · Cited by 175 · see citing works

The hnRNP A1 protein regulates HIV‐1 tat splicing via a novel intron silencer element

Tange, T. Ø., Damgaard, C. K., Guth, S., et al. (2001) · The EMBO Journal · doi:10.1093/emboj/20.20.5748 · Cited by 175 · see citing works

Pre-mRNA splicing in the absence of an SR protein RS domainPreprint

Zhu, J., & Krainer, A. R. (2000) · Genes & Development · doi:10.1101/gad.189500 · Cited by 175 · see citing works

Stage-specific changes in SR splicing factors and alternative splicing in mammary tumorigenesis

Stickeler, E., Kittrell, F. S., Medina, D., & Berget, S. M. (1999) · Oncogene · doi:10.1038/sj.onc.1202671 · Cited by 175 · see citing works

Multiple RRMs Contribute to RNA Binding Specificity and Affinity for Polypyrimidine Tract Binding Protein

Pérez, I. C., McAfee, J. G., & Patton, J. G. (1997) · Biochemistry · doi:10.1021/bi9711745 · Cited by 174 · see citing works

Activation of c-src neuron-specific splicing by an unusual RNA element in vivo and in vitro

Black, D. L. (1992) · Cell · doi:10.1016/0092-8674(92)90291-j · Cited by 172 · see citing works

Functional characterization of SR and SR‐related genes in Caenorhabditis elegans

Longman, D., Johnstone, I. L., & Cáceres, J. F. (2000) · The EMBO Journal · doi:10.1093/emboj/19.7.1625 · Cited by 171 · see citing works

The splicing factor‐associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation

Petersen‐Mahrt, S. K., Nilsson, C. E., Öhrmalm, C., Matthews, D. A., Russell, W. C., & Akusjärvi, G. (1999) · The EMBO Journal · doi:10.1093/emboj/18.4.1014 · Cited by 171 · see citing works

Identification by mass spectrometry and functional analysis of novel proteins of the yeast [U4/U6·U5] tri‐snRNP

GOTTSCHALK, A. R., Neubauer, G., Banroques, J., et al. (1999) · The EMBO Journal · doi:10.1093/emboj/18.16.4535 · Cited by 171 · see citing works

Regulation of Nuclear Localization during Signaling

Cyert, M. (2001) · Journal of Biological Chemistry · doi:10.1074/jbc.r100012200 · Cited by 170 · see citing works

The simian retrovirus-1 constitutive transport element, unlike the HIV-1 RRE, uses factors required for cellular mRNA export

Saavedra, C., Felber, B. K., & Izaurralde, E. (1997) · Current Biology · doi:10.1016/s0960-9822(06)00288-0 · Cited by 169 · see citing works

SR proteins escort the U4/U6.U5 tri-snRNP to the spliceosome.

Roscigno, R. F., & García-Blanco, M. A. (1995) · PubMed · Cited by 167 · see citing works

CD44 Acts Both as a Growth‐ and Invasiveness‐Promoting Molecule and as a Tumor‐Suppressing Cofactor

Herrlich, P. A., Morrison, H., Sleeman, J. P., Orian‐Rousseau, V., König, H., Weg‐Remers, S., & Ponta, H. (2000) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2000.tb06704.x · Cited by 166 · see citing works

The msl-2 dosage compensation gene of Drosophila encodes a putative DNA-binding protein whose expression is sex specifically regulated by Sex-lethal

Bashaw, G. J., & Baker, B. S. (1995) · Development · doi:10.1242/dev.121.10.3245 · Cited by 165 · see citing works

A predominantly nuclear protein affecting cytoplasmic localization of β-actin mRNA in fibroblasts and neurons

Gu, W., Pan, F., Zhang, H., Bassell, G. J., & Singer, R. H. (2002) · The Journal of Cell Biology · doi:10.1083/jcb.200105133 · Cited by 163 · see citing works

Splicing Regulation at the Second Catalytic Step by Sex-lethal Involves 3′ Splice Site Recognition by SPF45

Lallena, M. J., Chalmers, K. J., Llamazares, S., Lamond, A. I., & Valcárcel, J. (2002) · Cell · doi:10.1016/s0092-8674(02)00730-4 · Cited by 161 · see citing works

Structure of tandem RNA recognition motifs from polypyrimidine tract binding protein reveals novel features of the RRM fold

Conte, M. R., Grüne, T., Ghuman, J., Kelly, G. P., Ladas, A., Matthews, S., & Curry, S. (2000) · The EMBO Journal · doi:10.1093/emboj/19.12.3132 · Cited by 160 · see citing works

A structured retroviral RNA element that mediates nucleocytoplasmic export of intron-containing RNA

Ernst, R. K., Bray, M., Rekosh, D., & Hammarskjöld, M.-L. (1997) · Molecular and Cellular Biology · doi:10.1128/mcb.17.1.135 · Cited by 159 · see citing works

Polypyrimidine tract binding protein interacts with sequences involved in alternative splicing of beta-tropomyosin pre-mRNA.

Mulligan, G., Guo, W., Wormsley, S., & Helfman, D. M. (1992) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(19)74066-6 · Cited by 158 · see citing works

SC35 Plays a Role in T Cell Development and Alternative Splicing of CD45

Wang, H., Xu, X., Ding, J.-H., Bermingham, J. R., & Fu, X. (2001) · Molecular Cell · doi:10.1016/s1097-2765(01)00181-2 · Cited by 158 · see citing works

Coupling of signal transduction to alternative pre‐mRNA splicing by a composite splice regulator

König, H., Ponta, H., & Herrlich, P. (1998) · The EMBO Journal · doi:10.1093/emboj/17.10.2904 · Cited by 157 · see citing works

A CTD function linking transcription to splicing

Corden, J. L., & Patturajan, M. (1997) · Trends in Biochemical Sciences · doi:10.1016/s0968-0004(97)01125-0 · Cited by 157 · see citing works

Pre-mRNA splicing of IgM exons M1 and M2 is directed by a juxtaposed splicing enhancer and inhibitorPreprint

Kan, J. L. C., & Green, M. R. (1999) · Genes & Development · doi:10.1101/gad.13.4.462 · Cited by 156 · see citing works

Molecular Genetic Dissection of the Sex-Specific and Vital Functions of the Drosophila melanogaster Sex Determination Gene fruitless

Anand, A., Villella, A., Ryner, L. C., Carlo, T., Goodwin, S. F., Song, H., Gailey, D. A., Morales, A., Hall, J. C., Baker, B. S., et al. (2001) · Genetics · doi:10.1093/genetics/158.4.1569 · Cited by 156 · see citing works

An Intronic Splicing Silencer Causes Skipping of the IIIb Exon of Fibroblast Growth Factor Receptor 2 through Involvement of Polypyrimidine Tract Binding Protein

Carstens, R. P., Wagner, E. J., & García-Blanco, M. A. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.19.7388-7400.2000 · Cited by 156 · see citing works

Regulation of alternative pre-mRNA splicing by a novel repeated hexanucleotide element.Preprint

Huh, G. S., & Hynes, R. O. (1994) · Genes & Development · doi:10.1101/gad.8.13.1561 · Cited by 155 · see citing works

Alternative isoform regulation in human tissue transcriptomes

Wang, E. T., Sandberg, R., Luo, S., Khrebtukova, I., Zhang, L., Mayr, C., Kingsmore, S. F., Schroth, G. P., & Burge, C. B. (2008) · Nature · doi:10.1038/nature07509 · Cited by 5,181 · see citing works

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes

Siepel, A., Bejerano, G., Pedersen, J. S., Hinrichs, A. S., Hou, M., Rosenbloom, K., Clawson, H., Spieth, J., Hillier, L. W., Richards, S., et al. (2005) · Genome Research · doi:10.1101/gr.3715005 · Cited by 4,408 · see citing works

The Spliceosome: Design Principles of a Dynamic RNP Machine

Wahl, M. C., Will, C. L., & Lührmann, R. (2009) · Cell · doi:10.1016/j.cell.2009.02.009 · Cited by 2,665 · see citing works

Complementary Sequence-Mediated Exon Circularization

Zhang, X.-O., Wang, H.-B., Zhang, Y., Lu, X., Chen, L.-L., & Yang, L. (2014) · Cell · doi:10.1016/j.cell.2014.09.001 · Cited by 1,999 · see citing works

Spliceosome Structure and Function

Will, C. L., & Luhrmann, R. (2011) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a003707 · Cited by 1,829 · see citing works

The MicroRNA miR-124 Promotes Neuronal Differentiation by Triggering Brain-Specific Alternative Pre-mRNA Splicing

Makeyev, E. V., Zhang, J., Carrasco, M. A., & Maniatis, T. (2007) · Molecular Cell · doi:10.1016/j.molcel.2007.07.015 · Cited by 1,395 · see citing works

Mechanisms and Regulation of Alternative Pre-mRNA Splicing

Lee, Y., & Rio, D. C. (2015) · Annual Review of Biochemistry · doi:10.1146/annurev-biochem-060614-034316 · Cited by 1,291 · see citing works

Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches

Chen, M., & Manley, J. L. (2009) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2777 · Cited by 1,284 · see citing works

Characterizing the RNA targets and position-dependent splicing regulation by TDP-43

Tollervey, J. R., Curk, T., Rogelj, B., Briese, M., Cereda, M., Kayikci, M., König, J., Hortobágyi, T., Nishimura, A. L., Župunski, V., et al. (2011) · Nature Neuroscience · doi:10.1038/nn.2778 · Cited by 1,165 · see citing works

CLIP Identifies Nova-Regulated RNA Networks in the Brain

Ule, J., Jensen, K. B., Ruggiu, M., Mele, A., Ule, A., & Darnell, R. B. (2003) · Science · doi:10.1126/science.1090095 · Cited by 1,120 · see citing works

Alternative splicing and evolution: diversification, exon definition and function

Keren, H., Lev-Maor, G., & Ast, G. (2010) · Nature Reviews Genetics · doi:10.1038/nrg2776 · Cited by 1,082 · see citing works

Context-dependent control of alternative splicing by RNA-binding proteins

Fu, X.-D., & Ares, M. (2014) · Nature Reviews Genetics · doi:10.1038/nrg3778 · Cited by 1,044 · see citing works

Chromatin organization marks exon-intron structure

Schwartz, S., Meshorer, E., & Ast, G. (2009) · Nature Structural &amp; Molecular Biology · doi:10.1038/nsmb.1659 · Cited by 638 · see citing works

Variation in alternative splicing across human tissues

Yeo, G., Holste, D., Kreiman, G., & Burge, C. B. (2004) · Genome Biology · doi:10.1186/gb-2004-5-10-r74 · Cited by 584 · see citing works

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

Boutz, P. L., Stoilov, P., Li, Q., Lin, C.-H., Chawla, G., Ostrow, K., Shiue, L., Ares, M., & Black, D. L. (2007) · Genes &amp; Development · doi:10.1101/gad.1558107 · Cited by 577 · see citing works

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells

Yeo, G. W., Coufal, N. G., Liang, T. Y., Peng, G. E., Fu, X.-D., & Gage, F. H. (2009) · Nature Structural &amp; Molecular Biology · doi:10.1038/nsmb.1545 · Cited by 572 · see citing works

Alternative splicing and nonsense-mediated decay modulate expression of important regulatory genes in Arabidopsis

Kalyna, M., Simpson, C. G., Syed, N. H., Lewandowska, D., Marquez, Y., Kusenda, B., Marshall, J., Fuller, J., Cardle, L., McNicol, J., et al. (2012) · Nucleic Acids Research · doi:10.1093/nar/gkr932 · Cited by 480 · see citing works

Integrative Genome-wide Analysis Reveals Cooperative Regulation of Alternative Splicing by hnRNP Proteins

Huelga, S. C., Vu, A. Q., Arnold, J. D., Liang, T. Y., Liu, P. P., Yan, B. Y., Donohue, J. P., Shiue, L., Hoon, S., Brenner, S., et al. (2012) · Cell Reports · doi:10.1016/j.celrep.2012.02.001 · Cited by 470 · see citing works

Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping

Xue, Y., Zhou, Y., Wu, T., Zhu, T., Ji, X., Kwon, Y.-S., Zhang, C., Yeo, G., Black, D. L., Sun, H., et al. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.12.003 · Cited by 469 · see citing works

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Lovci, M. T., Ghanem, D., Marr, H., Arnold, J., Gee, S., Parra, M., Liang, T. Y., Stark, T. J., Gehman, L. T., Hoon, S., et al. (2013) · Nature Structural &amp; Molecular Biology · doi:10.1038/nsmb.2699 · Cited by 385 · see citing works

Artificial intelligence and machine learning-aided drug discovery in central nervous system diseases: State-of-the-arts and future directions

Vatansever, S., Schlessinger, A., Wacker, D., Kaniskan, H. Ü., Jin, J., Zhou, M., & Zhang, B. (2021) · Medicinal Research Reviews · doi:10.1002/med.21764 · Cited by 429 · see citing works

The alternative splicing repressors hnRNP A1/A2 and PTB influence pyruvate kinase isoform expression and cell metabolism

Clower, C. V., Chatterjee, D., Wang, Z., Cantley, L. C., Vander Heiden, M. G., & Krainer, A. R. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0914845107 · Cited by 424 · see citing works

Neuronal regulation of alternative pre-mRNA splicing

Li, Q., Lee, J.-A., & Black, D. L. (2007) · Nature Reviews Neuroscience · doi:10.1038/nrn2237 · Cited by 376 · see citing works

The neurogenetics of alternative splicing

Vuong, C. K., Black, D. L., & Zheng, S. (2016) · Nature Reviews Neuroscience · doi:10.1038/nrn.2016.27 · Cited by 340 · see citing works

Revealing global regulatory features of mammalian alternative splicing using a quantitative microarray platform

Pan, Q., Shai, O., Misquitta, C., Zhang, W., Saltzman, A. L., Mohammad, N., Babak, T., Siu, H., Hughes, T. R., Morris, Q. D., et al. (2004) · Molecular Cell · doi:10.1016/j.molcel.2004.12.004 · Cited by 323 · see citing works

Noisy Splicing Drives mRNA Isoform Diversity in Human Cells

Pickrell, J. K., Pai, A. A., Gilad, Y., & Pritchard, J. K. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001236 · Cited by 311 · see citing works

Tau gene alternative splicing: expression patterns, regulation and modulation of function in normal brain and neurodegenerative diseases

Andreadis, A. (2005) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2004.08.010 · Cited by 311 · see citing works

Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2

Zhang, C., Zhang, Z., Castle, J., Sun, S., Johnson, J., Krainer, A. R., & Zhang, M. Q. (2008) · Genes &amp; Development · doi:10.1101/gad.1703108 · Cited by 300 · see citing works

Homologues of the <i>Caenorhabditis elegans</i> Fox-1 Protein Are Neuronal Splicing Regulators in Mammals

Underwood, J. G., Boutz, P. L., Dougherty, J. D., Stoilov, P., & Black, D. L. (2005) · Molecular and Cellular Biology · doi:10.1128/mcb.25.22.10005-10016.2005 · Cited by 272 · see citing works

The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function

Gehman, L. T., Meera, P., Stoilov, P., Shiue, L., O'Brien, J. E., Meisler, M. H., Ares, M., Otis, T. S., & Black, D. L. (2012) · Genes &amp; Development · doi:10.1101/gad.182477.111 · Cited by 213 · see citing works

Widespread splicing changes in human brain development and aging

Mazin, P., Xiong, J., Liu, X., Yan, Z., Zhang, X., Li, M., He, L., Somel, M., Yuan, Y., Phoebe Chen, Y., et al. (2013) · Molecular Systems Biology · doi:10.1038/msb.2012.67 · Cited by 216 · see citing works

Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2

Keppetipola, N., Sharma, S., Li, Q., & Black, D. L. (2012) · Critical Reviews in Biochemistry and Molecular Biology · doi:10.3109/10409238.2012.691456 · Cited by 201 · see citing works

An unappreciated role for RNA surveillance

Hillman, R. T., Green, R. E., & Brenner, S. E. (2004) · Genome Biology · doi:10.1186/gb-2004-5-2-r8 · Cited by 193 · see citing works

Fox-1 family of RNA-binding proteins

Kuroyanagi, H. (2009) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-009-0120-5 · Cited by 187 · see citing works

The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation

Li, Q., Zheng, S., Han, A., Lin, C.-H., Stoilov, P., Fu, X.-D., & Black, D. L. (2014) · eLife · doi:10.7554/elife.01201 · Cited by 174 · see citing works

Hu Antigen R (HuR) Functions as an Alternative Pre-mRNA Splicing Regulator of Fas Apoptosis-promoting Receptor on Exon Definition

Izquierdo, J. M. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.m800017200 · Cited by 156 · see citing works

Genome-wide Analysis of Alternative Pre-mRNA Splicing

Ben-Dov, C., Hartmann, B., Lundgren, J., & Valcárcel, J. (2008) · Journal of Biological Chemistry · doi:10.1074/jbc.r700033200 · Cited by 151 · see citing works

Auto- and Cross-Regulation of the hnRNP L Proteins by Alternative Splicing

Rossbach, O., Hung, L.-H., Schreiner, S., Grishina, I., Heiner, M., Hui, J., & Bindereif, A. (2009) · Molecular and Cellular Biology · doi:10.1128/mcb.01689-08 · Cited by 141 · see citing works

YB-1 binds to CAUC motifs and stimulates exon inclusion by enhancing the recruitment of U2AF to weak polypyrimidine tracts

Wei, W.-J., Mu, S.-R., Heiner, M., Fu, X., Cao, L.-J., Gong, X.-F., Bindereif, A., & Hui, J. (2012) · Nucleic Acids Research · doi:10.1093/nar/gks579 · Cited by 124 · see citing works

OLego: fast and sensitive mapping of spliced mRNA-Seq reads using small seeds

Wu, J., Anczuków, O., Krainer, A. R., Zhang, M. Q., & Zhang, C. (2013) · Nucleic Acids Research · doi:10.1093/nar/gkt216 · Cited by 123 · see citing works

Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner

Zhou, H.-L., Hinman, M. N., Barron, V. A., Geng, C., Zhou, G., Luo, G., Siegel, R. E., & Lou, H. (2011) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1103344108 · Cited by 136 · see citing works

Discovery of Glucocorticoid Receptor-β in Mice with a Role in Metabolism

Hinds, T. D., Ramakrishnan, S., Cash, H. A., Stechschulte, L. A., Heinrich, G., Najjar, S. M., & Sanchez, E. R. (2010) · Molecular Endocrinology · doi:10.1210/me.2009-0411 · Cited by 129 · see citing works

Nova autoregulation reveals dual functions in neuronal splicing

Dredge, B. K., Stefani, G., Engelhard, C. C., & Darnell, R. B. (2005) · The EMBO Journal · doi:10.1038/sj.emboj.7600630 · Cited by 125 · see citing works

Functional coordination of alternative splicing in the mammalian central nervous system

Fagnani, M., Barash, Y., Ip, J. Y., Misquitta, C., Pan, Q., Saltzman, A. L., Shai, O., Lee, L., Rozenhek, A., Mohammad, N., et al. (2007) · Genome Biology · doi:10.1186/gb-2007-8-6-r108 · Cited by 120 · see citing works

Alternative pre-mRNA splicing in neurons: growing up and extending its reach

Zheng, S., & Black, D. L. (2013) · Trends in Genetics · doi:10.1016/j.tig.2013.04.003 · Cited by 115 · see citing works

Mutation of a U2 snRNA Gene Causes Global Disruption of Alternative Splicing and Neurodegeneration

Jia, Y., Mu, J. C., & Ackerman, S. L. (2012) · Cell · doi:10.1016/j.cell.2011.11.057 · Cited by 114 · see citing works

Genome-wide Analysis of Alternative Pre-mRNA Splicing and RNA-Binding Specificities of the Drosophila hnRNP A/B Family Members

Blanchette, M., Green, R. E., MacArthur, S., Brooks, A. N., Brenner, S. E., Eisen, M. B., & Rio, D. C. (2009) · Molecular Cell · doi:10.1016/j.molcel.2009.01.022 · Cited by 86 · see citing works

Alternative Splicing of <i>Cyr61</i> Is Regulated by Hypoxia and Significantly Changed in Breast Cancer

Hirschfeld, M., zur Hausen, A., Bettendorf, H., Jäger, M., & Stickeler, E. (2009) · Cancer Research · doi:10.1158/0008-5472.can-08-1997 · Cited by 86 · see citing works

Polypyrimidine tract‐binding protein is essential for early mouse development and embryonic stem cell proliferation

Shibayama, M., Ohno, S., Osaka, T., Sakamoto, R., Tokunaga, A., Nakatake, Y., Sato, M., & Yoshida, N. (2009) · The FEBS Journal · doi:10.1111/j.1742-4658.2009.07380.x · Cited by 82 · see citing works

The Tissue-Specific RNA Binding Protein T-STAR Controls Regional Splicing Patterns of Neurexin Pre-mRNAs in the Brain

Ehrmann, I., Dalgliesh, C., Liu, Y., Danilenko, M., Crosier, M., Overman, L., Arthur, H. M., Lindsay, S., Clowry, G. J., Venables, J. P., et al. (2013) · PLoS Genetics · doi:10.1371/journal.pgen.1003474 · Cited by 82 · see citing works

Pre-mRNA processing factors meet the DNA damage response

Montecucco, A., & Biamonti, G. (2013) · Frontiers in Genetics · doi:10.3389/fgene.2013.00102 · Cited by 69 · see citing works

The RNA-binding protein SUP-12 controls muscle-specific splicing of the ADF/cofilin pre-mRNA in <i>C. elegans</i>

Anyanful, A., Ono, K., Johnsen, R. C., Ly, H., Jensen, V., Baillie, D. L., & Ono, S. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200407085 · Cited by 58 · see citing works

Promotion of exon 6 inclusion in HuD pre-mRNA by Hu protein family members

Wang, H., Molfenter, J., Zhu, H., & Lou, H. (2010) · Nucleic Acids Research · doi:10.1093/nar/gkq028 · Cited by 49 · see citing works

Identification and characterization of a neuron-specific isoform of protrudin

Ohnishi, T., Shirane, M., Hashimoto, Y., Saita, S., & Nakayama, K. I. (2014) · Genes to Cells · doi:10.1111/gtc.12109 · Cited by 33 · see citing works

Deep generalizable prediction of RNA secondary structure via base pair motif energy

Zhu, H., Tang, F., Quan, Q., Chen, K., Xiong, P., & Zhou, S. K. (2025) · Nature Communications · doi:10.1038/s41467-025-60048-1 · Cited by 17 · see citing works

Pan-cancer analysis of systematic batch effects on somatic sequence variations

Choi, J.-H., Hong, S.-E., & Woo, H. G. (2017) · BMC Bioinformatics · doi:10.1186/s12859-017-1627-7 · Cited by 14 · see citing works

Alternative Splice Variants Encoding Unstable Protein Domains Exist in the Human Brain

Homma, K., Kikuno, R. F., Nagase, T., Ohara, O., & Nishikawa, K. (2004) · Journal of Molecular Biology · doi:10.1016/j.jmb.2004.09.028 · Cited by 19 · see citing works

EST comparison indicates 38% of human mRNAs contain possible alternative splice forms

Brett, D. J., Hanke, J., Lehmann, G., et al. (2000) · FEBS Letters · doi:10.1016/s0014-5793(00)01581-7 · Cited by 302 · see citing works

DETECTION OF NOVEL SPLICE FORMS IN HUMAN AND MOUSE USING CROSS-SPECIES APPROACH

Kan, Z., Castle, J. C., Johnson, J. M., et al. (2003) · Pacific Symposium on Biocomputing (PSB) · doi:10.1142/9789812704856_0005 · Cited by 18 · see citing works

Positional Correlations in Splicing Patterns-Its Application to Prediction of Splice Sites

Watanabe, T., Kudo, Y., & Shimizu, T. (2002) · Proceedings Genome Informatics Workshop/Genome informatics · doi:10.11234/gi1990.13.426

TAPAS: tools to assist the targeted protein quantification of human alternative splice variants

Yang, J., Sabidó, E., Serrano, L., & Kiel, C. (2014) · Bioinformatics · doi:10.1093/bioinformatics/btu428 · Cited by 1 · see citing works