Black, Douglas L.

Mechanisms of Alternative Pre-Messenger RNA Splicing

Black, D. L. (2003) · Annual Review of Biochemistry

RNA Research and SplicingRNA regulation and disease

Cited by 2,704

A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons

Boutz, P. L., Stoilov, P., Li, Q., Lin, C.-H., Chawla, G., Ostrow, K., Shiue, L., Ares, M., & Black, D. L. (2007) · Genes & Development

RNA Research and SplicingRNA regulation and disease

Cited by 577

Genome-wide Analysis of PTB-RNA Interactions Reveals a Strategy Used by the General Splicing Repressor to Modulate Exon Inclusion or Skipping

Xue, Y., Zhou, Y., Wu, T., Zhu, T., Ji, X., Kwon, Y.-S., Zhang, C., Yeo, G., Black, D. L., Sun, H., et al. (2009) · Molecular Cell

RNA Research and SplicingRNA regulation and disease

Cited by 469

Rbfox proteins regulate alternative mRNA splicing through evolutionarily conserved RNA bridges

Lovci, M. T., Ghanem, D., Marr, H., Arnold, J., Gee, S., Parra, M., Liang, T. Y., Stark, T. J., Gehman, L. T., Hoon, S., et al. (2013) · Nature Structural & Molecular Biology

RNA Research and SplicingRNA regulation and disease

Cited by 385

Neuronal regulation of alternative pre-mRNA splicing

Li, Q., Lee, J.-A., & Black, D. L. (2007) · Nature Reviews Neuroscience

RNA Research and SplicingRNA regulation and disease

Cited by 376

The neurogenetics of alternative splicing

Vuong, C. K., Black, D. L., & Zheng, S. (2016) · Nature Reviews Neuroscience

RNA Research and SplicingGenetics and Neurodevelopmental Disorders

Cited by 340

The splicing regulator Rbfox1 (A2BP1) controls neuronal excitation in the mammalian brain

Gehman, L. T., Stoilov, P., Maguire, J., Damianov, A., Lin, C.-H., Shiue, L., Ares, M., Mody, I., & Black, D. L. (2011) · Nature Genetics

RNA Research and SplicingEpilepsy research and treatment

Cited by 331

MicroRNAs regulate the expression of the alternative splicing factor nPTB during muscle development

Boutz, P. L., Chawla, G., Stoilov, P., & Black, D. L. (2007) · Genes & Development

RNA Research and SplicingMicroRNA in disease regulation

Cited by 304

Homologues of the Caenorhabditis elegans Fox-1 Protein Are Neuronal Splicing Regulators in Mammals

Underwood, J. G., Boutz, P. L., Dougherty, J. D., Stoilov, P., & Black, D. L. (2005) · Molecular and Cellular Biology

RNA Research and SplicingRNA regulation and disease

Cited by 272

Molecular basis of RNA recognition by the human alternative splicing factor Fox-1

Auweter, S. D., Fasan, R., Reymond, L., Underwood, J. G., Black, D. L., Pitsch, S., & Allain, F. H. (2006) · The EMBO Journal

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 264

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

Zheng, S., Gray, E. E., Chawla, G., Porse, B. T., O'Dell, T. J., & Black, D. L. (2012) · Nature Neuroscience

RNA Research and SplicingNeuroscience and Neuropharmacology Research

Cited by 254

Cytoplasmic Rbfox1 Regulates the Expression of Synaptic and Autism-Related Genes

Lee, J.-A., Damianov, A., Lin, C.-H., Fontes, M., Parikshak, N. N., Anderson, E. S., Geschwind, D. H., Black, D. L., & Martin, K. C. (2016) · Neuron

RNA Research and SplicingGenetics and Neurodevelopmental Disorders

Cited by 232

The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function

Gehman, L. T., Meera, P., Stoilov, P., Shiue, L., O'Brien, J. E., Meisler, M. H., Ares, M., Otis, T. S., & Black, D. L. (2012) · Genes & Development

RNA Research and SplicingGenetics and Neurodevelopmental Disorders

Cited by 213

Neuronal regulation of pre-mRNA splicing by polypyrimidine tract binding proteins, PTBP1 and PTBP2

Keppetipola, N., Sharma, S., Li, Q., & Black, D. L. (2012) · Critical Reviews in Biochemistry and Molecular Biology

RNA Research and SplicingRNA regulation and disease

Cited by 201

The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation

Li, Q., Zheng, S., Han, A., Lin, C.-H., Stoilov, P., Fu, X.-D., & Black, D. L. (2014) · eLife

RNA Research and SplicingGenetics and Neurodevelopmental Disorders

Cited by 174

Autoregulation of Fox protein expression to produce dominant negative splicing factors

Damianov, A., & Black, D. L. (2010) · RNA

RNA Research and SplicingRNA regulation and disease

Cited by 120

Alternative pre-mRNA splicing in neurons: growing up and extending its reach

Zheng, S., & Black, D. L. (2013) · Trends in Genetics

RNA Research and SplicingRNA regulation and disease

Cited by 115

Rbfox1 Regulates Synaptic Transmission through the Inhibitory Neuron-Specific vSNARE Vamp1

Vuong, C. K., Wei, W., Lee, J.-A., Lin, C.-H., Damianov, A., de la Torre-Ubieta, L., Halabi, R., Otis, K. O., Martin, K. C., O’Dell, T. J., et al. (2018) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 102

Inhibiting amyloid-β cytotoxicity through its interaction with the cell surface receptor LilrB2 by structure-based design

Cao, Q., Shin, W. S., Chan, H., Vuong, C. K., Dubois, B., Li, B., Murray, K. A., Sawaya, M. R., Feigon, J., Black, D. L., et al. (2018) · Nature Chemistry

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 75