Structure of an E3:E2∼Ub Complex Reveals an Allosteric Mechanism Shared among RING/U-box Ligases

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Items 301–347 of 347

  1. Multidimensional Nuclear Magnetic Resonance of Biomolecules
    David J. Craik, James Horne, Martin J. Scanlon, Scott R. Nichols, Dominique P. Frueh · 2016 · Encyclopedia of Analytical Chemistry
  2. Faculty Opinions recommendation of Dual RING E3 architectures regulate multiubiquitination and ubiquitin chain elongation by APC/C.
    Hiroyuki Yamano · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  3. Faculty Opinions recommendation of Analysis of ubiquitin recognition by the HECT ligase E6AP provides insight into its linkage specificity.
    Thorsten Hoppe · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
  4. Recruitment of ubiquitin E 2 enzymes is determined jointly by the U‐box domains and substrates of E 3 ligases
    Bo Jin, Bei Li, Junyao Qu, Yiheng Sun, Mengran Wang, Changjiang Yang, Yuchen Fan, Yanan Wang, Peng Xu, Haiying Sun et al. · 2024 · FEBS Letters
  5. Additional file 1 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Zhen Liu, Lei Wang, Yuanming Li, Jinyong Zhu, Zhitao Li, Limin Chen, Hongyang Li, Tianbin Shi, Panfeng Yao, Zhenzhen Bi et al. · 2024 · Figshare
  6. Structural Analyses of a GABARAP∼ATG3 Conjugate Uncover a Novel Non-covalent Ubl-E2 Backside Interaction
    Kazuto Ohashi, Takanori Otomo · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  7. Design of linked-domain protein inhibitors of UBE2D as tools to study cellular ubiquitination
    Zara Bukhari, Li Gu, Anneroos E Nederstigt, Logan J. Cope, Derek L. Bolhuis, Kim Harvey, Tristan Allen, Spencer Hill, Yujie Yang, Guy Lawson et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
  8. Arkadia and Ark2c Promote Substrate Ubiquitylation with Multiple E2 Enzymes
    Catherine L. Day, Claudia Roßig, Andrej Paluda, Rebecca Chen, A.J. Middleton · 2025 · SSRN Electronic Journal
  9. Structural Insights into the GABARAP–ATG3 Backside Interaction and Apo ATG3 Conformation
    Kazuto Ohashi, Gerard J. A. Kroon, Takanori Otomo · 2025 · Biochemistry
  10. ISGylation Mechanism Uncovers Conformational Specificity for HECT-family E3 ligase
    Pritiranjan Sahoo, Gloria Grace Parmar, Dipti Ranjan Lenka, Mohini Sherawat, Bhagya Shri Trivedi, Atul Kumar · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  11. Enhancing enzymatic bioconjugation efficiency via installation of a substrate recruitment domain
    Christopher Shelby, Kaylee P. Kuzelka, Jonathan M. Ellis, Zhiyuan Yao, Amelia C. McCue, Rodney Park, Satish K. Nair, Albert A. Bowers, Brian A. Kuhlman · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  12. Synthetic tools to redirect the ubiquitin E3 ligase activity of a plant-specific N-recognin
    Keely E.A. Oldham, Suyan Yee, Kai Xun Chan, Peter D. Mabbitt · 2026 · Nature Communications
  13. Linked-domain inhibitors designed to block UBE2D induce the unfolded protein response
    Zara Bukhari, Li Gu, Anneroos E Nederstigt, Logan J. Cope, Derek L. Bolhuis, Kim Harvey, Tristan Allen, Spencer Hill, Yujie Yang, Guy Lawson et al. · 2025 · Cell chemical biology
  14. Additional file 8 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao PanFeng, Zhenzhen Bi et al. · 2024 · Figshare
  15. Additional file 14 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao, Panfeng, Zhenzhen Bi et al. · 2024 · Figshare
  16. Additional file 10 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao, Panfeng, Zhenzhen Bi et al. · 2024 · Figshare
  17. Additional file 5 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao, Panfeng, Zhenzhen Bi et al. · 2024 · Figshare
  18. Additional file 4 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao PanFeng, Zhenzhen Bi et al. · 2024 · Figshare
  19. Additional file 9 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao, Panfeng, Zhenzhen Bi et al. · 2024 · Figshare
  20. Additional file 6 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao PanFeng, Zhenzhen Bi et al. · 2024 · Figshare
  21. Additional file 15 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao, Panfeng, Zhenzhen Bi et al. · 2024 · Figshare
  22. Additional file 2 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao PanFeng, Zhenzhen Bi et al. · 2024 · Figshare
  23. Additional file 13 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao, Panfeng, Zhenzhen Bi et al. · 2024 · Figshare
  24. Additional file 1 of Crystal structure of rice APIP6 reveals a new dimerization mode of RING-type E3 ligases that facilities the construction of its working model
    Zheng, Yangyang, Zhang, Xin, Liu, Yang, Tongtong Zhu, Wu, Xuefeng, Yuese Ning, Liu, Junfeng, Dongli Wang · 2024 · Figshare
  25. Additional file 3 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao, Panfeng, Zhenzhen Bi et al. · 2024 · Figshare
  26. Additional file 11 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao PanFeng, Zhenzhen Bi et al. · 2024 · Figshare
  27. Additional file 12 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao, Panfeng, Zhenzhen Bi et al. · 2024 · Figshare
  28. Additional file 2 of Crystal structure of rice APIP6 reveals a new dimerization mode of RING-type E3 ligases that facilities the construction of its working model
    Zheng, Yangyang, Zhang, Xin, Liu, Yang, Zhu, Tongtong, Wu, Xuefeng, Yuese Ning, Liu, Junfeng, Dongli Wang · 2024 · Figshare
  29. Additional file 16 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao, Panfeng, Zhenzhen Bi et al. · 2024 · Figshare
  30. Additional file 7 of Genome-wide analysis of the U-box E3 ligases gene family in potato (Solanum tuberosum L.) and overexpress StPUB25 enhance drought tolerance in transgenic Arabidopsis
    Liu, Zhen, Lei Wang, Yuanming Li, Jinyong Zhu, Li, Zhitao, Chen, Limin, Hongyang Li, Tianbin Shi, Yao, Panfeng, Zhenzhen Bi et al. · 2024 · Figshare
  31. Engineering an orthogonal ubiquitin transfer cascade with RING E3 RNF38 by phage display to reveal its regulation of nuclear transport
    Li Zhou, In Ho Jeong, Hang Li, Nicolas Rios, Jing zhang, Xiaoyu Wang, Shu Liu, Yayun Xie, Wei Wei, Geon Ho Jeong et al. · 2026 · Journal of Biological Chemistry
  32. Enhancing Enzymatic Bioconjugation Efficiency via Computer-Based Installation of a Substrate Recruitment Domain
    Christopher Shelby, Kaylee P. Kuzelka, Jonathan M. Ellis, Zhiyuan Yao, Amelia C. McCue, Rodney Park, Satish K. Nair, Albert A. Bowers, Brian A. Kuhlman · 2026 · Bioconjugate Chemistry
  33. Caractérisation des processus d'ubiquitination régulant le facteur de transcription NF-kappaB au cours de l’activation lymphocytaire Rôle de l’E3 ligase TRIM13 et de la déubiquitinase USP34
    Emeline M. Hatchi · 2014 · theses.fr (ABES)
  34. Regulation of proteotoxicity through atypical NEDDylation
    Chantal M. Maghames · 2016 · theses.fr (ABES)
  35. Disrupting E3 ubiquitin ligase protein–protein interactions in cancer: chemical modalities, mechanisms, and therapeutic opportunities
    Emadeldin M. Kamel, Sally Mostafa Khadrawy, Mohamed A.M. Ali, Noha A. Ahmed, Nour Y. S. Yassin, Saleh Alkhedhairi, Faris F. Aba Alkhayl, Al Mokhtar Lamsabhi · 2026 · Biochemical Pharmacology
  36. Ubiquitinome dynamics and regulation by DUB2 during Leishmania differentiation
    Sergios Antoniou, Nathaniel G. Jones, Vincent Geoghegan, Adam Dowle, Charlotte McNiven, Rachel Neish, Chris MacDonald, Anthony J. Wilkinson, Jeremy Charles Mottram · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  37. The Novel Compound SIC-19 Triggers CUL4B-Mediated Ubiquitination and Degradation of SIK2
    Yeqiu Zou, Jiaqi Liu, Shunpeng Zhu, Qi Li, Qi Li, Fang Wang, Youguo Chen, J Zhou · 2026 · Molecular and Cellular Biology
  38. Regulation of cellular functions and diseases by the MARCH E3 ubiquitin ligases
    Q P Zhang, Yu-Ting Qiao, Shu Li · 2026 · Cell Insight
  39. The UBE2/E2 ubiquitin-conjugating enzyme family at the interface of tumor biology and antitumor immunity: mechanisms, biomarkers, and therapeutic opportunities
    Hai Zhao, Jiaxin Yang, Fan Yang · 2026 · Frontiers in Immunology
  40. In-situ cryo-ET of mouse embryos reveals cytoplasmic lattices contain ubiquitin-charged E2-E3 ligase assemblies
    Kashish Singh, Katarina Harasimov, Kathy K. Niakan, Andrew P. Carter · 2026 · The EMBO Journal
  41. Structures of the UBR4 complex reveal a giant arena to capture diverse substrates for ubiquitin chain elongation
    Daniel B. Grabarczyk, Tim Clausen · 2026 · FEBS Journal
  42. Photoreactive crosslinkers capture the ubiquitin–E2–E3 ligases intermediates
    Tingting Yao, Tatiana G. Kutateladze · 2026 · Biochemical Journal
  43. Ubiquitin E3 ligase activity in TRIpartite Motif (TRIM) family proteins
    Jane Dudley-Fraser, Katrin Rittinger · 2026 · Biochemical Society Transactions
  44. Hydrophobic Tag Protein Degraders: An Emerging Therapeutic Strategy for Cancer
    Tania Aguilera Pineda, Siddhartha Kumar, Gargi Ghosal, Amarnath Natarajan, Adam R. Karpf · 2026 · Pharmaceuticals
  45. RING E3 ligase TRIM8 is structurally selective for UBE2N-mediated ubiquitination
    Jane Dudley-Fraser, Diego Esposito, Katrin Rittinger · 2026 · Journal of Biological Chemistry
  46. Ubiquitinome dynamics and regulation by DUB2 during Leishmania differentiation
    Sergios Antoniou, Nathaniel G. Jones, Vincent Geoghegan, Adam Dowle, Charlotte Hughes, Rachel Neish, Chris MacDonald, Anthony J. Wilkinson, Jeremy Charles Mottram · 2026 · Molecular & Cellular Proteomics
  47. Phosphorylated Hsp70-CHIP BLItz Data
    Rick Page · 2018 · Harvard Dataverse