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Cited by 679

The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.

Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles

Open access
Dobrovolskaia, Marina A., Patri, Anil K., Zheng, Jiwen, Clogston, Jeffrey D., Ayub, Nader, Aggarwal, Parag, Neun, Barry W., Hall, Jennifer B., McNeil, Scott E.·2009·Nanomedicine: Nanotechnology, Biology and Medicine

Abstract

Nanoparticle size and plasma binding profile contribute to a particle’s longevity in the bloodstream, which can have important consequences for therapeutic efficacy. In this study an approximate doubling in nanoparticle hydrodynamic size was observed upon in vitro incubation of 30- and 50-nm colloidal gold in human plasma. Plasma proteins that bind the surface of citrate-stabilized gold colloids have been identified. Effects of protein binding on the nanoparticle hydrodynamic size, elements of coagulation, and the complement system have been investigated. The difference in size measurements obtained from dynamic light scattering, electron microscopy, and scanning probe microscopy are also discussed.

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Crossref · 10.1016/j.nano.2008.08.001

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Metadata

Authors
Dobrovolskaia, M. A., Patri, A. K., Zheng, J., Clogston, J. D., Ayub, N., Aggarwal, P., Neun, B. W., Hall, J. B., & McNeil, S. E.
Venue
Nanomedicine: Nanotechnology, Biology and Medicine
Publisher
Elsevier BV
Published
2009-06
Volume
5
Issue
2
Pages
106-117
ISSN
1549-9634 (ISSN-L)
OpenAlex
W2027239458
Cited by
679
References
1
FWCI
7.34
Type
journal article
Language
en
Open access
green

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CoChat. (2026). Citation check: Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles. https://app.cochat.ai/papers/10.1016/j.nano.2008.08.001
The paper
Dobrovolskaia, M. A., Patri, A. K., Zheng, J., Clogston, J. D., Ayub, N., Aggarwal, P., Neun, B. W., Hall, J. B., & McNeil, S. E. (2009). Interaction of colloidal gold nanoparticles with human blood: effects on particle size and analysis of plasma protein binding profiles. Nanomedicine: Nanotechnology, Biology and Medicine. https://doi.org/10.1016/j.nano.2008.08.001

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

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