The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Self-powered implantable electrical stimulator for osteoblasts’ proliferation and differentiation
Abstract
Abstract Osteoporosis and osteoporosis-related fractures were considered as worldwide diseases and arose wide public concern, the costs for incident osteoporosis-related fractures in United States is nearly $17 billion in 2005 [ 1 ], leading to large economic burden. Here, we proposed a self-powered flexible and implantable electrical stimulator, which consisting of a triboelectric nanogenerator (TENG) and a flexible interdigitated electrode. It demonstrated that this self-powered electrical stimulator significantly promoted osteoblasts' attachment, proliferation and differentiation, the level of intracellular Ca2+ was up-regulated after electrical stimulation. In addition, the self-powered electrical stimulator was further demonstrated to be driven by the daily movement of a rat, suggesting the practical use as an implantable medical electronic device to electrically induce osteoblasts' differentiation and bone remodeling. Described above, the self-powered electrical stimulator probably could meddle bone homeostasis, alleviate osteoporosis and osteoporosis-related fractures. This work shows great progress not only for TENGs’ applications in implantable medical devices but also for clinical therapy of osteoporosis and osteoporosis-related fractures.
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Citations
Cites
Incidence and Economic Burden of Osteoporosis-Related Fractures in the United States, 2005–2025
Burge, R., Dawson-Hughes, B., Solomon, D. H., Wong, J. B., King, A., & Tosteson, A. (2007) · Journal of Bone and Mineral Research · doi:10.1359/jbmr.061113 · Cited by 4,026
In Vivo Powering of Pacemaker by Breathing‐Driven Implanted Triboelectric Nanogenerator
Zheng, Q., Shi, B., Fan, F., Wang, X., Yan, L., Yuan, W., Wang, S., Liu, H., Li, Z., & Wang, Z. L. (2014) · Advanced Materials · doi:10.1002/adma.201402064 · Cited by 603
Self-citationFully Bioabsorbable Natural‐Materials‐Based Triboelectric Nanogenerators
Jiang, W., Li, H., Liu, Z., Li, Z., Tian, J., Shi, B., Zou, Y., Ouyang, H., Zhao, C., Zhao, L., et al. (2018) · Advanced Materials · doi:10.1002/adma.201801895 · Cited by 449
Self-citationEffective Wound Healing Enabled by Discrete Alternative Electric Fields from Wearable Nanogenerators
Long, Y., Wei, H., Li, J., Yao, G., Yu, B., Ni, D., Gibson, A. L., Lan, X., Jiang, Y., Cai, W., et al. (2018) · ACS Nano · doi:10.1021/acsnano.8b07038 · Cited by 397
Wnt signaling and cellular metabolism in osteoblasts
Karner, C. M., & Long, F. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-016-2425-5 · Cited by 295
In Vivo Self‐Powered Wireless Transmission Using Biocompatible Flexible Energy Harvesters
Kim, D. H., Shin, H. J., Lee, H., Jeong, C. K., Park, H., Hwang, G., Lee, H., Joe, D. J., Han, J. H., Lee, S. H., et al. (2017) · Advanced Functional Materials · doi:10.1002/adfm.201700341 · Cited by 245
Tibial nonunion treated with direct current, capacitive coupling, or bone graft
Brighton, C. T., Shaman, P., Bruce, R., Esterhai, J. L., Pollack, S. R., & Friedenberg, Z. B. (1995) · Clinical Orthopaedics and Related Research · doi:10.1097/00003086-199512000-00034 · Cited by 116
Cited by
Recent progress of triboelectric nanogenerators: From fundamental theory to practical applications
Luo, J., & Wang, Z. L. (2020) · EcoMat · doi:10.1002/eom2.12059 · Cited by 451
Shuai, C., Liu, G., Yang, Y., Qi, F., Peng, S., Yang, W., He, C., Wang, G., & Qian, G. (2020) · Nano Energy · doi:10.1016/j.nanoen.2020.104825 · Cited by 406
Wang, T., Ouyang, H., Luo, Y., Xue, J., Wang, E., Zhang, L., Zhou, Z., Liu, Z., Li, X., Tan, S., et al. (2024) · Science Advances · doi:10.1126/sciadv.adi6799 · Cited by 161
Self-citationSelf-powered pulsed direct current stimulation system for enhancing osteogenesis in MC3T3-E1
Zhang, Y., Xu, L., Liu, Z., Cui, X., Xiang, Z., Bai, J., Jiang, D., Xue, J., Wang, C., Lin, Y., et al. (2021) · Nano Energy · doi:10.1016/j.nanoen.2021.106009 · Cited by 88
Self-citationWu, H., Wei, S., Chen, S., Pan, H., Pan, W., Huang, S., Tsai, M., & Yang, P. (2022) · Advanced Science · doi:10.1002/advs.202105974 · Cited by 75
Metadata
- Authors
- Tian, J., Shi, R., Liu, Z., Ouyang, H., Yu, M., Zhao, C., Zou, Y., Jiang, D., Zhang, J., & Li, Z.
- Venue
- Nano Energy
- Publisher
- Elsevier BV
- Published
- 2019-05
- Volume
- 59
- Pages
- 705-714
- ISSN
- 2211-2855 (ISSN-L)
- OpenAlex
- W2921555806
- Cited by
- 196
- References
- 7
- FWCI
- 7.55
- Type
- journal article
- Language
- en
- Open access
- closed
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- Tian, J., Shi, R., Liu, Z., Ouyang, H., Yu, M., Zhao, C., Zou, Y., Jiang, D., Zhang, J., & Li, Z. (2019). Self-powered implantable electrical stimulator for osteoblasts’ proliferation and differentiation. Nano Energy. https://doi.org/10.1016/j.nanoen.2019.02.073
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