Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

Clinical diagnosis of Alzheimer's disease: Report of the NINCDS‐ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease

McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915

Neuropathological stageing of Alzheimer-related changes.

Braak, H., & Braak, E. (1991) · Acta Neuropathologica · doi:10.1007/bf00308809 · Cited by 16,123

Inflammation and Alzheimer’s disease

Akiyama, H. (2000) · Neurobiology of Aging · doi:10.1016/s0197-4580(00)00124-x · Cited by 4,514

Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound‐B

Klunk, W. E., Engler, H., Nordberg, A., Wang, Y., Blomqvist, G., Holt, D. P., Bergström, M., Savitcheva, I., Huang, G., Estrada, S., et al. (2004) · Annals of Neurology · doi:10.1002/ana.20009 · Cited by 4,496

Microglia: a sensor for pathological events in the CNS

Kreutzberg, G. W. (1996) · Trends in Neurosciences · doi:10.1016/0166-2236(96)10049-7 · Cited by 4,396

Immunization with amyloid-β attenuates Alzheimer-disease-like pathology in the PDAPP mouse

Schenk, D., Barbour, R., Dunn, W., Gordon, G., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., Khan, K., et al. (1999) · Nature · doi:10.1038/22124 · Cited by 3,160

The molecular pathology of Alzheimer's disease

Selkoe, D. J. (1991) · Neuron · doi:10.1016/0896-6273(91)90052-2 · Cited by 2,708

Amyloid deposition as the central event in the aetiology of Alzheimer’s disease

Hardy, J., & Allsop, D. (1991) · Trends in Pharmacological Sciences · doi:10.1016/0165-6147(91)90609-v · Cited by 2,538

Synapse Loss and Microglial Activation Precede Tangles in a P301S Tauopathy Mouse Model

Yoshiyama, Y., Higuchi, M., Zhang, B., Huang, S.-M., Iwata, N., Saido, T. C., Maeda, J., Suhara, T., Trojanowski, J. Q., & Lee, V. M.-Y. (2007) · Neuron · doi:10.1016/j.neuron.2007.01.010 · Cited by 2,208

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

Bard, F., Cannon, C., Barbour, R., Burke, R.-L., Games, D., Grajeda, H., Guido, T., Hu, K., Huang, J., Johnson-Wood, K., et al. (2000) · Nature Medicine · doi:10.1038/78682 · Cited by 2,012

Neuroinflammation in long-term cognitive impairment after aneurysmal subarachnoid hemorrhage

Tack, R. W. P., Tolboom, N., Viol, B. M., Golla, S. S. V., van Berckel, B. N. M., van der Schaaf, I. C., Boellaard, R., Luca, A. D., van Zandvoort, M. J. E., Visser‐Meily, J. M. A., et al. (2025) · International Journal of Stroke · doi:10.1177/17474930251362004 · Cited by 4

Neuroinflammation in comorbid depression in Alzheimer's disease: A pilot study using post-mortem brain tissue

Lin, J. T., Morisaki, M., Sampathkumar, S. A., Lau, L. C., Boche, D., Khandaker, G. M., & Sinclair, L. I. (2024) · Neuroscience Applied · doi:10.1016/j.nsa.2024.104051 · Cited by 5

A radioligand for in vitro autoradiography of CSF1R in post-mortem CNS tissues

Foss, C. A., Naik, R., Das, D., Cha, H., Minn, I., Hall, A., Finley, P. A., Wu, S. J., Du, Y., Dannals, R. F., et al. (2024) · EJNMMI Research · doi:10.1186/s13550-024-01133-2 · Cited by 5

Are Inflammatory Profiles the Key to Personalized Alzheimer's treatment?

Brothers, H. M., & Wilcock, D. M. (2013) · Neurodegenerative Disease Management · doi:10.2217/nmt.13.40 · Cited by 3

Lewy body dementia

Delenclos, M., Moussaud, S., & McLean, P. J. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805120-7.00008-7 · Cited by 5

Aβ Imaging in Aging, Alzheimer’s Disease and Other Neurodegenerative Conditions

Villemagne, V. L., Fodero‐Tavoletti, M. T., Yates, P. A., Masters, C. L., & Rowe, C. C. (2014) · Springer eBooks · doi:10.1007/978-3-642-54307-4_10 · Cited by 4

Neuroprotective Effects of Glucosinolates

Angeloni, C., Hrelia, S., & Malaguti, M. (2017) · Reference series in phytochemistry · doi:10.1007/978-3-319-25462-3_20 · Cited by 4

Coupling relationship between glucose and oxygen metabolisms to serve as an imaging biomarker for Alzheimer’s disease

Yang, Z. X., Sheng, J., Zhang, Q., Chou, J. T. C., Xin, Y., & Wang, L. (2025) · Scientific Reports · doi:10.1038/s41598-025-01927-x · Cited by 3

APP Modulates Aβ-Induced Activation of Microglia in Mouse Model of Alzheimer's Disease

Datta, D. (2017) · Journal of Neuroscience · doi:10.1523/jneurosci.3122-16.2017 · Cited by 3

Multiple System Atrophy

Zamora, C. A., Muhleman, M., & Castillo, M. (2021) · Springer eBooks · doi:10.1007/978-3-030-82367-2_31 · Cited by 3

Klinisch-validierte molekulare Biomarker neurodegenerativer Demenzerkrankungen

Wiltfang, J. (2014) · Der Nervenarzt · doi:10.1007/s00115-014-4086-7 · Cited by 3

SPECT/PET Findings in Lewy Body Dementia

Ducksbury, R., Whitfield, T. J., & Walker, Z. (2014) · Springer eBooks · doi:10.1007/978-3-642-54307-4_17 · Cited by 3

Nonamyloid Pet Biomarkers and Alzheimer'S Disease: Current and Future Perspectives

Schilling, L. P., Leuzy, A., Zimmer, E. R., Gauthier, S. G., & Rosa‐Neto, P. (2014) · Future Neurology · doi:10.2217/fnl.14.40 · Cited by 4

Research progress in neuroimaging of sporadic early-onset Alzheimer’s disease

Zhang, X., & Yang, C. (2026) · Frontiers in Neurology · doi:10.3389/fneur.2026.1788814 · Cited by 2

Development of early biomarkers of Alzheimer's disease: A precision medicine perspective

Sarkar, S., Das, N., & Sambamurti, K. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-824010-6.00006-x · Cited by 2

The 18 kDa translocator protein is associated with microglia in the hippocampus of non-demented elderly subjects

Tournier, B. B., Snoeijs, C., Tsartsalis, S., Amossé, Q., Farchoukh, R., Kövari, E., Ceyzériat, K., & Millet, P. (2022) · Aging Brain · doi:10.1016/j.nbas.2022.100045 · Cited by 2

Optimisation of synthesis, purification and reformulation of (R)-[N-Methyl-11C]PK11195 for in vivo PET imaging studies

Alves, V., Abrunhosa, A., & Castelo-Branco, M. S. (2013) · IEEE Portuguese Meeting on Bioengineering · doi:10.1109/enbeng.2013.6518428 · Cited by 2

Alzheimer's Disease: Approaches to Pathogenesis in the Genomic Age

Sutherland, G. T., & Jillian, J. (2012) · InTech eBooks · doi:10.5772/36505 · Cited by 2

Diagnosis of Dementia Using Nuclear Medicine Imaging Modalities

Merissa, N., Garrett, M., & Scott, P. J. H. (2011) · InTech eBooks · doi:10.5772/25283 · Cited by 2

Advances in Dementia Imaging

Clopton, D., & Druzgal, T. J. (2013) · Seminars in Roentgenology · doi:10.1053/j.ro.2013.10.006 · Cited by 2

Atypical parkinsonism, parkinsonism-plus syndromes, and secondary parkinsonian disorders

Fahn, S., Jankovic, J. J., & Hallett, M. (2011) · Elsevier eBooks · doi:10.1016/b978-1-4377-2369-4.00009-3 · Cited by 2

BIPOLAR DISORDER AND DEMENTIA: A CLOSE LINK

Piccinni, A., Marazziti, D., Callari, A., Franceschini, C., Veltri, A., Bartolommei, N., Ciaponi, B., Mariani, M. G., & Vanelli, F. (2015) · Cited by 2

A Note on Changing Approach to Diagnosis of Alzheimer’s Disease

Tartaglione, A., & Sette, M. D. (2014) · EMJ Neurology · doi:10.33590/emjneurol/10310003 · Cited by 2

A Specialized Nutritional Formulation Prevents Hippocampal Glial Activation and Memory Impairment Induced by Amyloid-β Oligomers in Mice

Siqueira, L. D., Celes, A. P. M., dos Santos, H., & Ferreira, S. T. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-210139 · Cited by 2

Predict Disease Progression With Reaction Rate Equation Modeling of Multimodal MRI and PET

Su, L., Huang, Y., Wang, Y., Rowe, J. B., & O'Brien, J. T. (2018) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2018.00306 · Cited by 2

A REVIEW ON MICROGLIA: ROLE IN NEUROINFLAMMATION, SCREENING MODELS AND THERAPEUTIC STRATEGIES FOR TREATMENT

Choudhury, S., & Vellapandian, C. (2019) · International Research Journal of Pharmacy · doi:10.7897/2230-8407.10013 · Cited by 2

Microglial targets for effective therapies of Alzheimer’s disease

Klegeris, A. (2020) · Frontiers in Drug Chemistry and Clinical Research · doi:10.15761/fdccr.1000145 · Cited by 2

Imaging synaptic microstructure and synaptic loss in vivo in early Alzheimer’s DiseasePreprint

Venkataraman, A. V., Bishop, C., Mansur, A., Rizzo, G., Lewis, Y. L., Kocagöncü, E., Lingford-Hughes, A. R., Huiban, M., Passchier, J., Rowe, J. B., et al. (2021) · medRxiv · doi:10.1101/2021.11.23.21266746 · Cited by 2

Transplantation of wild-type hematopoietic stem and progenitor cells rescue Alzheimer’s disease in a mouse model and highlights the central role of microglia in disease pathogenesisPreprint

Mishra, P., Silva, A., Sharma, J., Nguyen, J., Pizzo, D. P., Sahoo, D., & Cherqui, S. (2022) · Research Square · doi:10.21203/rs.3.rs-1602615/v1 · Cited by 2

Aβ Imaging in Aging, Alzheimer’s Disease, and Other Neurodegenerative Conditions

Villemagne, V. L., Doré, V., Burnham, S. C., & Rowe, C. C. (2020) · Springer eBooks · doi:10.1007/978-3-030-53168-3_10 · Cited by 2

Finding the Fire: Mapping Brain Temperature Elevations as a Surrogate of Focal Neuroinflammation

Sharma, A. A., Nenert, R. E., & Szaflarski, J. P. (2025) · Neuromethods · doi:10.1007/978-1-0716-4494-2_9 · Cited by 2

Increased circulating TREM2+ microglial extracellular vesicles in aged APP/PS1 Alzheimer's disease rats

Myers, S. J., Medapati, M. R., Allman, B. L., Pasternak, S., Whitehead, S. N., & Roseborough, A. D. (2026) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2026.101261 · Cited by 1

The relation between neuroinflammation, amyloid-β load, grey matter loss and brain activity in visual object recognition regions in Alzheimer's Disease

Jorge, L., Canário, N., Martins, R., Abrunhosa, A., Santana, I. J., & Castelo-Branco, M. S. (2025) · Neuroimage Reports · doi:10.1016/j.ynirp.2025.100305 · Cited by 1

Genetic validation of ABI3 p.Ser209Phe variant and its effects on early brain pathology in asymptomatic elderly individuals

Koivumäki, M., Martiskainen, H., Takalo, M., Lehtisalo, J., Ngandu, T., FinnGen, Snellman, A., Hiltunen, M. O., & Rinne, J. O. (2026) · Alzheimer s Research & Therapy · doi:10.1186/s13195-026-01984-y · Cited by 1

Advances in hiPSC ‐Derived Brain Organoids as a Model to Study Neuroinflammation in Alzheimer's Disease

Maciel, E. M. A., Silva, N. C., Santos, L. G. P., & Ribeiro, F. M. (2026) · Journal of Neurochemistry · doi:10.1111/jnc.70416 · Cited by 1

Is there already value in “total body PET” imaging in neurology?

Hammers, A. (2026) · British Journal of Radiology · doi:10.1093/bjr/tqag126 · Cited by 1

MRI- and PET-Based Imaging Markers for the Diagnosis of Alzheimer’s Disease

Teipel, S. J., Sperling, R. A., Skudlarski, P., Jack, C. R., Hampel, H. J., Fellgiebel, A., & Herholz, K. (2012) · Advances in biological psychiatry · doi:10.1159/000335393 · Cited by 1

Quantitative Analysis of Formation of Active Avoidance Behavior in the Hippocampus Coagulated and Intact White Albino Rats

Tsagareli, S. N., Archvadze, N. G., & Tavdishvili, O. (2012) · Journal of Behavioral and Brain Science · doi:10.4236/jbbs.2012.21002 · Cited by 1

Möglichkeiten moderner Bildgebungstechnologien im Rahmen der Frühdiagnostik von Alzheimererkrankung

Unschuld, P. G. (2015) · Therapeutische Umschau · doi:10.1024/0040-5930/a000674 · Cited by 1

Current Evidence and Potential Pathogenetic Mechanisms of Helicobacter pylori Involvement in Neuroinflammatory Pathologies

Kountouras, J. (2013) · ImmunoGastroenterology · doi:10.7178/ig.37 · Cited by 1

The Role of Adaptive and Innate Immunity in Alzheimer’s Disease

Holmes, C. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108539623.012 · Cited by 1

Textural properties of microglial activation in Alzheimer’s disease as measured by (R)-[11C]PK11195 PET

Pais, M. L., Jorge, L., Martins, R., Canário, N., Xavier, A. C., Bernardes, R., Abrunhosa, A., Santana, I. J., & Castelo-Branco, M. S. (2023) · Brain Communications · doi:10.1093/braincomms/fcad148 · Cited by 1

Neuroinflamação e doenças neurodegenerativas: Mecanismos, biomarcadores e intervenções terapêuticas. Uma revisão de literatura

Lino, L. A., Mendes, L. M. C., Ribeiro, T. D. A. A., Gomes, C. V. C., Filho, E. B. E., da Silva, I. M., Silva, L. M., Emerik, N. B., Camilo, A. B. P. C., Fernandes, J. R. P. D. C., et al. (2024) · Research Society and Development · doi:10.33448/rsd-v13i8.46731 · Cited by 3

PET Imaging of Microglia Activation in Neuropsychiatric Disorders with Potential Infectious Origin

Klein, H. C., de Witte, L. D., Bransfield, R. C., & Deyn, P. P. D. (2014) · Springer eBooks · doi:10.1007/978-3-642-54307-4_34 · Cited by 1

Original article. Patterns of microglial innate immune responses elicited by amyloid β1–42and lipopolysaccharide: the similarities of the differences

Boondam, Y., & Cheepsunthorn, P. (2014) · Asian Biomedicine · doi:10.5372/1905-7415.0802.299 · Cited by 1

PET Imaging of Microglia Activation and Infection in Neuropsychiatric Disorders with Potential Infectious Origin

Klein, H. C., de Witte, L. D., Bransfield, R. C., & Deyn, P. P. D. (2020) · Springer eBooks · doi:10.1007/978-3-030-53168-3_32 · Cited by 1

Huntington’s Disease

Zamora, C. A., Muhleman, M., & Castillo, M. (2021) · Springer eBooks · doi:10.1007/978-3-030-82367-2_35 · Cited by 1

Neuroimaging in multiple system atrophy

Tondo, G., Comi, C., Naldi, A., de Natale, E. R., & Politis, M. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-821651-4.00008-7 · Cited by 1

Magnetic Resonance and Molecular Imaging in Psychiatry

Howes, O. D. (2015) · Elsevier eBooks · doi:10.1016/b978-0-08-097086-8.27040-2 · Cited by 1

Blood-Brain Barrier Permeability and Inflammation in Cerebral Small Vessel Disease

Walsh, J. (2019) · Apollo (University of Cambridge) · doi:10.17863/cam.50869 · Cited by 2

The Impact of Genetic Polymorphisms on Neuroreceptor Imaging

Willeit, M., Kasper, S. F., & Praschak-Rieder, N. (2014) · Springer eBooks · doi:10.1007/978-3-642-42014-6_6

Investigation of the Effects of Image Signal-to-Noise Ratio on TSPO PET Quantification of Neuroinflammation

Constable, C. (2013) · The Sydney eScholarship Repository (The University of Sydney)

PL‐05‐03: Metabolic and molecular imaging markers throughout the course of Alzheimer's disease

Herholz, K. (2010) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2010.05.515

The translocator protein as a drug target in Alzheimer's

Chua, S. W., Kassiou, M., & Ittner, L. M. (2014)

PET Imaging in Neuroinflammation

Brooks, D. J. (2014) · Springer eBooks · doi:10.1007/978-3-319-08046-8_9

E Deputy Editor: Dr J.A.J.M. Deckers E Editorial Board:

Aarnink, R., Beckett, J., Maniawski, P., Neitzel, U., Silfen, E., Zeitler, G., Zimmermann, W., & Highway, B. E. (2009)

Linking Molecular Neurobiology to Therapeutic Approaches for Alzheimer’s Disease with PET

Luiten, P. G. M., Masman, M. F., Dobos, N., Nyakas, C. J., de Vries, E. F. J., Dierckx, R., & Eisel, U. L. M. (2014) · Springer eBooks · doi:10.1007/978-3-642-54307-4_20

Neuroimaging in the assessment and treatment of dementias

Surendranathan, A., & O'Brien, J. T. (2016) · British Journal of Healthcare Management · doi:10.12968/bjhc.2016.22.2.63

Mechanisms of palmitate induced amyloidogenesis in Alzheimer's Disease mediated by astrocytes

Liu, L. (2013) · doi:10.25335/hzqa-1c05

PATHOGENIC ROLE OF MICROGLIA-DERIVED MICROVESICLES IN NEURODEGENERATION

Joshi, P. (2014) · Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) · doi:10.13130/joshi-pooja_phd2014-01-16

Molecular imaging in dementia: journey to the end of the night

Villemagne, V. L. (2009)

Klinisch-validierte molekulare Biomarker neurodegenerativer Demenzerkrankungen

Psychiatrie, K. F. (2014)

PET Imaging as a Diagnostic Tool in Alzheimer’s Disease

Rinne, J. O. (2016) · Methods in pharmacology and toxicology · doi:10.1007/978-1-4939-3560-4_13

PET studies on disease progression and treatment efficacy in Alzheimer’s disease and mild cognitive impairment

Okello, A. (2011) · Spiral (Imperial College London) · doi:10.25560/7110

Imaging Approaches to Cerebral Cortex Pathology

Bartha, R., & Lee, T.-Y. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-801942-9.00003-3

The Relationship between CD14 and Microglia in Peripheral Blood Mononuclear Cells in Patients with Alzheimer’s Disease

赵, 雪. (2017) · International Journal of Psychiatry and Neurology · doi:10.12677/ijpn.2017.61001

Lewy Body Dementia and the Role of Inflammation

Surendranathan, A. (2018) · Apollo (University of Cambridge) · doi:10.17863/cam.30607

Positron emissiontomography imaging of neuroinflammation in Multiple Sclerosis with a second generation translocator protein PET radioligand

Colasanti, A. (2014) · Spiral (Imperial College London) · doi:10.25560/25285

The biology of cognitive decline and reduced survival in Parkinson disease : prognostic factors in a population-based cohort

Bäckström, D. C. (2019) · KTH Publication Database DiVA (KTH Royal Institute of Technology)

The Impact of Genetic Polymorphisms on Neuroreceptor Binding: Results from PET and SPECT Neuroreceptor Imaging Studies

Graf, I., Willeit, M., Kasper, S. F., & Praschak-Rieder, N. (2020) · Springer eBooks · doi:10.1007/978-3-030-53176-8_6 · Cited by 1

Neuroinflammation characterizes the earliest changes in Alzheimer’s disease pathology and associated subjective cognitive impairment in adult hydrocephalus biopsiesPreprint

Huang, W., Bartosch, A. M. W., Xiao, H., Flowers, X. E., Leskinen, S., Tomljanovic, Z., Iodice, G. M., Boyett, D. M., Spinazzi, E. F., Menon, V., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.10.01.322511

Positron emission tomography imaging agents for evaluating the pathologic features of Alzheimer's disease and drug development

Huang, Y. H., Jia, H., & Bao, W. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-816475-4.00013-6

Role of Inflammation in Lewy Body Dementia

Surendranathan, A., & O'Brien, J. T. (2021) · Cambridge University Press eBooks · doi:10.1017/9781108539623.011

Central Nervous System Molecular Imaging

Sólnes, L. B., Jacobs, A. H., Coughlin, J. M., Du, Y., Goel, R., Hammoud, D. A., & Pomper, M. G. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-816386-3.00088-0

Microglial Activation and Neuroinflammation

Kreisl, W. C. (2021) · Springer eBooks · doi:10.1007/978-3-030-82367-2_17

Elucidation of mechanisms linking periodontitis to Alzheimer’s disease

Hiro, T. A. K. E. (2022) · Journal of The Society of Japanese Women Scientists · doi:10.5939/sjws.22007

Current awareness in geriatric psychiatry

(2009) · International Journal of Geriatric Psychiatry · doi:10.1002/gps.2116

Current Awareness in Labelled Compounds and Radiopharmaceuticals

(2009) · Journal of Labelled Compounds and Radiopharmaceuticals · doi:10.1002/jlcr.1549

DHA for Optimal Health

Meyer, B. J. (2018) · MDPI eBooks · doi:10.3390/books978-3-03842-972-2

Der Einfluss von (-)-Δ9-trans- Tetrahydrocannabinol und Cannabidiol auf die Alzheimer-Pathologie im 5XFAD-Mausmodell

Schleicher, E. M. (2021) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-8990

The effect of reminder focused positive psychiatry suicide safety (RFPP-S) on COVID-19 related PTSD with PGD

Ahmadi, N., Steinberg, A. M., & Pynoos, R. S. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.08.012

Faculty Opinions recommendation of The methodology of TSPO imaging with positron emission tomography.

Perani, D. (2017) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.730624735.793537458

Therapeutic and immunomodulatory functions of the translocator protein in Alzheimer's disease

Fairley, L. H. (2022) · DR-NTU (Nanyang Technological University) · doi:10.32657/10356/160865

APOE ε4 gene dose effect on imaging and blood biomarkers of glial reactivity and β-amyloid pathologyPreprint

Snellman, A., Ekblad, L. L., Tuisku, J., Koivumäki, M., Ashton, N. J., Lantero‐Rodriguez, J., Karikari, T. K., Helin, S., Bucci, M., Löyttyniemi, E., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2022.09.19.508484

Positron emission tomography imaging of neuroinflammation

(2023) · Advances in magnetic resonance technology and applications · doi:10.1016/b978-0-323-91771-1.00007-1

Dementia

(2023) · Advances in magnetic resonance technology and applications · doi:10.1016/b978-0-323-91771-1.00026-5

Immune dysregulation and neurodegenerative diseases

Cipollini, V., Troili, F., & Giubilei, F. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-85841-0.00015-8

Additional file 3 of Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learning

Yuen, S. C., Liang, X., Zhu, H., Jia, Y., & Leung, S.-W. (2021) · Figshare · doi:10.6084/m9.figshare.14945066

Additional file 2 of Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learning

Yuen, S. C., Liang, X., Zhu, H., Jia, Y., & Leung, S.-W. (2021) · Figshare · doi:10.6084/m9.figshare.14945063

Additional file 1 of Prediction of differentially expressed microRNAs in blood as potential biomarkers for Alzheimer’s disease by meta-analysis and adaptive boosting ensemble learning

Yuen, S. C., Liang, X., Zhu, H., Jia, Y., & Leung, S.-W. (2021) · Figshare · doi:10.6084/m9.figshare.14945060

Advancing age, nutraceuticals, and neuroprotection

Woźniak, L. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-323-95735-9.00001-2

Interaction between mitochondrial translocator protein and aging in inflammatory responses in mouse hippocampusPreprint

Lai, K. O., Tham, N., Fairley, L. H., Naik, R. R., Wang, Y., Langley, S. R., & Barron, A. M. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.19.598824

Imaging Biomarkers of Neuroinflammations: TSPO Agents

Arnone, A., & Alongi, P. (2024) · Springer eBooks · doi:10.1007/978-3-031-54196-4_19

Alzheimer’s Disease

Chan, D., Spires‐Jones, T. L., Provenzano, F. A., Glennon, E. B. C., & Duff, K. (2025) · Oxford University Press eBooks · doi:10.1093/med/9780190065324.003.0020

Fluid and Imaging Markers of Glial Reactivity

Suárez‐Calvet, M. (2025) · Springer eBooks · doi:10.1007/978-3-031-80849-4_6

TSPO contributes to neuropathology and cognitive deficits in Alzheimer’s diseasePreprint

Ceyzériat, K., Badina, A. M., Abjean, L., Meyer, L., Bouteldja, F., Bałkota, M., Amossé, Q., Prudhomme, O., Middleton, R. J., Liu, G.-J., et al. (2025) · Research Square · doi:10.21203/rs.3.rs-7008246/v1

Genetic Validation of ABI3 p.S209F Variant and Its effects On Early Brain Pathology in Asymptomatic Elderly Individuals

Koivumäki, M., Martiskainen, H., Takalo, M., Lehtisalo, J., Ngandu, T., Snellman, A., Hiltunen, M., & Rinne, J. O. (2025) · doi:10.21203/rs.3.rs-7823342/v1

Additional file 1 of Hippocampal glucose uptake as a surrogate of metabolic change of microglia in Alzheimer’s disease

Choi, H., Choi, Y., Lee, E. J., Kim, H., Lee, Y., Kwon, S., Hwang, D. W., & Lee, D. S. (2021) · Figshare · doi:10.6084/m9.figshare.16551264

Additional file 1 of Regional desynchronization of microglial activity is associated with cognitive decline in Alzheimer’s disease

Zatcepin, A., Gnörich, J. S., Rauchmann, B.-S., Bartos, L. M., Wagner, S., Franzmeier, N., Malpetti, M., Xiang, X., Shi, Y., Parhizkar, S., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26952306

Additional file 1 of The longitudinal trajectory of CSF sTREM2: the alzheimer’s disease neuroimaging initiative

Wang, Y., Ye, M., Ji, Q., Liu, Q., Xu, X., & Zhan, Y. (2024) · Figshare · doi:10.6084/m9.figshare.26739390

[PL1‐01]: The relationship between amyloid load, microglial activation, and cognition in Alzheimer's disease: PET findings

Brooks, D. J., Edison, P., Archer, H. A., Hinz, R., Gerhard, A., Hammers, A., Pavese, N., Tai, Y., Cuttler, D., Fox, N. C., et al. (2005) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2005.06.053

Microglial activation in Alzheimer's disease: an (R)-[11C]PK11195 positron emission tomography study

Schuitemaker, A., Kropholler, M. A., Boellaard, R., van der Flier, W. M., Kloet, R. W., van der Doef, T. F., Knol, D. L., Windhorst, A. D., Luurtsema, G., Barkhof, F., et al. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2012.04.021 · Cited by 175

In vivo changes in microglial activation and amyloid deposits in brain regions with hypometabolism in Alzheimer’s disease

Yokokura, M., Mori, N., Yagi, S., Yoshikawa, E., Kikuchi, M., Yoshihara, Y., Wakuda, T., Sugihara, G., Takebayashi, K., Suda, S., et al. (2011) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-010-1612-0 · Cited by 174

O1–03–01: Microglial activation in patients with mild cognitive impairment and Alzheimer's disease: A study using [11C](R)–PK11195 and PET

Schuitemaker, A., van Berckel, B. N. M., Boellaard, R., Kropholler, M. A., Lubberink, M., Jonker, C., Lammertsma, A. A., & Scheltens, P. (2006) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2006.05.044

Microglial activation and amyloid deposition in mild cognitive impairment: A PET study

Okello, A., Edison, P., Archer, H. A., Turkheimer, F. E., Kennedy, J., Bullock, R., Walker, Z., Kennedy, A., Fox, N., Rossor, M., et al. (2009) · Neurology · doi:10.1212/01.wnl.0000338622.27876.0d · Cited by 367