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Brain Metabolism and Microglia Activation in Mild Cognitive Impairment: A Combined [18F]FDG and [11C]-(R)-PK11195 PET Study

Tondo, G., Boccalini, C., Caminiti, S. P., Presotto, L., Filippi, M., Magnani, G., Frisoni, G. B., Iannaccone, S., & Perani, D. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201351 · Cited by 29

Pentraxins and Alzheimer's disease: At the interface between biomarkers and pharmacological targets

Osera, C., Pascale, A., Amadio, M., Venturini, L., Govoni, S. M., & Ricevuti, G. (2011) · Ageing Research Reviews · doi:10.1016/j.arr.2011.12.004 · Cited by 30

Hippocampal Glutamate NMDA Receptor Loss Tracks Progression in Alzheimer’s Disease: Quantitative Autoradiography in Postmortem Human Brain

Kravitz, E., Gaisler-Salomon, I., & Biegon, A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0081244 · Cited by 30

Translocator protein in late stage Alzheimer’s disease and Dementia with Lewy bodies brains

Xu, J., Sun, J., Perrin, R. J., Mach, R. H., Bales, K. R., Morris, J. C., Benzinger, T. L. S., & Holtzman, D. M. (2019) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.50837 · Cited by 31

Assessment of change in glucose metabolism in white matter of amyloid-positive patients with Alzheimer disease using F-18 FDG PET

Jeong, Y. J., Yoon, H. J., & Kang, D. (2017) · Medicine · doi:10.1097/md.0000000000009042 · Cited by 32

In Vitro Methodologies to Study the Role of Advanced Glycation End Products (AGEs) in Neurodegeneration

Chrysanthou, M., Estruch, I. M., Rietjens, I. M. C. M., Wichers, H. J., & Hoppenbrouwers, T. (2022) · Nutrients · doi:10.3390/nu14020363 · Cited by 31

The translocator protein (18 kDa) and its role in neuropsychiatric disorders

Barichello, T., Simões, L. R., Collodel, A., Giridharan, V. V., Dal‐Pizzol, F., Macêdo, D. S., & Quevedo, J. (2017) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2017.10.010 · Cited by 30

Gray matter changes related to microglial activation in Alzheimer's disease

Nicastro, N., Malpetti, M., Mak, E., Williams, G. B., Bevan-Jones, W. R., Carter, S. F., Passamonti, L., Fryer, T. D., Hong, Y. T., Aigbirhio, F. I., et al. (2020) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2020.06.010 · Cited by 30

Multimodality imaging of neurodegenerative disorders with a focus on multiparametric magnetic resonance and molecular imaging

Loftus, J. R., Puri, S., & Meyers, S. P. (2023) · Insights into Imaging · doi:10.1186/s13244-022-01358-6 · Cited by 30

Neuroimmune nexus of depression and dementia: Shared mechanisms and therapeutic targets

Herman, F. J., Simkovic, S. J., & Pasinetti, G. M. (2019) · British Journal of Pharmacology · doi:10.1111/bph.14569 · Cited by 29

Alzheimer's disease biomarkers: correspondence between human studies and animal models

Sabbagh, J. J., Kinney, J. W., & Cummings, J. L. (2013) · Neurobiology of Disease · doi:10.1016/j.nbd.2013.04.010 · Cited by 27

Activated microglial cells synthesize and secrete AGE-albumin

Byun, K., Bayarsaikhan, E., Kim, D., Son, M., Hong, J., Jeong, G.-B., Paek, S. H., Won, M.-H., & Lee, B. (2012) · Anatomy & Cell Biology · doi:10.5115/acb.2012.45.1.47 · Cited by 26

Neuroprotective effects and possible mechanisms of berberine in animal models of Alzheimer’s disease: a systematic review and meta-analysis

Dan, L., Hao, Y., Li, J., Wang, T., Zhao, W., Wang, H., Qiao, L., & Xie, P. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1287750 · Cited by 27

Brain Metabolites and Peripheral Biomarkers Associated with Neuroinflammation in Complex Regional Pain Syndrome Using [11C]-(R)-PK11195 Positron Emission Tomography and Magnetic Resonance Spectroscopy: A Pilot Study

Jung, Y.-H., Kim, H., Jeon, S. Y., Kwon, J. M., Lee, W. J., Kim, Y. C., Jang, J. H., Choi, S., Lee, J., & Kang, D. (2018) · Pain Medicine · doi:10.1093/pm/pny111 · Cited by 26

Improved Sleep, Memory, and Cellular Pathological Features of Tauopathy, Including the NLRP3 Inflammasome, after Chronic Administration of Trazodone in rTg4510 Mice

de Oliveira, P., Cella, C. V., Locker, N., Ravindran, K. K. G., Mendis, A., Wafford, K. A., Gilmour, G., Dijk, D., & Winsky‐Sommerer, R. (2022) · Journal of Neuroscience · doi:10.1523/jneurosci.2162-21.2022 · Cited by 25

Common and Rare Variants in TMEM175 Gene Concur to the Pathogenesis of Parkinson’s Disease in Italian Patients

Palomba, N. P., Fortunato, G., Pepe, G., Modugno, N., Pietracupa, S., Damiano, I., Mascio, G., Carrillo, F., Giovannantonio, L. G. D., Ianiro, L., et al. (2023) · Molecular Neurobiology · doi:10.1007/s12035-022-03203-9 · Cited by 27

An In Vivo 11C-(R)-PK11195 PET and In Vitro Pathology Study of Microglia Activation in Creutzfeldt-Jakob Disease

Iaccarino, L., Moresco, R. M., Presotto, L., Bugiani, O., Iannaccone, S., Giaccone, G., Tagliavini, F., & Perani, D. (2017) · Molecular Neurobiology · doi:10.1007/s12035-017-0522-6 · Cited by 26

Let’s make microglia great again in neurodegenerative disorders

Guillot‐Sestier, M., & Town, T. (2017) · Journal of Neural Transmission · doi:10.1007/s00702-017-1792-x · Cited by 26

Targeting Microglial Population Dynamics in Alzheimer’s Disease: Are We Ready for a Potential Impact on Immune Function?

Martin-Estebane, M., & Gomez-Nicola, D. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2020.00149 · Cited by 25

Innovative Molecular Imaging for Clinical Research, Therapeutic Stratification, and Nosography in Neuroscience

Beaurain, M., Salabert, A., Ribeiro, M. J., Arlicot, N., Damier, P., Jeune, F. L., Démonet, J., & Payoux, P. (2019) · Frontiers in Medicine · doi:10.3389/fmed.2019.00268 · Cited by 26

A new perspective for advanced positron emission tomography–based molecular imaging in neurodegenerative proteinopathies

Perani, D., Iaccarino, L., Lammertsma, A. A., Windhorst, A. D., Edison, P., Boellaard, R., Hansson, O., Nordberg, A. K., Jacobs, A. H., & IMBI Project (2019) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2019.02.004 · Cited by 25

CSF ferritin in the clinicopathological progression of Alzheimer’s disease and associations with APOE and inflammation biomarkers

Ayton, S., Janelidze, S., Kalinowski, P., Palmqvist, S., Belaidi, A. A., Stomrud, E., Roberts, A., Roberts, B. R., Hansson, O., & Bush, A. I. (2022) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp-2022-330052 · Cited by 27

Neuroimaging in dementia

Valkanova, V., & Ebmeier, K. P. (2014) · Maturitas · doi:10.1016/j.maturitas.2014.02.016 · Cited by 27

The isozyme selective phosphodiesterase-4 inhibitor, ABI-4, attenuates the effects of lipopolysaccharide in human cells and rodent models of peripheral and CNS inflammation

Hedde, J. R., Hanks, A. N., Schmidt, C. J., & Hughes, Z. A. (2017) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2017.04.015 · Cited by 24

[PL1‐01]: The relationship between amyloid load, microglial activation, and cognition in Alzheimer's disease: PET findings

Brooks, D. J., Edison, P., Archer, H. A., Hinz, R., Gerhard, A., Hammers, A., Pavese, N., Tai, Y., Cuttler, D., Fox, N. C., et al. (2005) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2005.06.053

Microglial activation in Alzheimer's disease: an (R)-[11C]PK11195 positron emission tomography study

Schuitemaker, A., Kropholler, M. A., Boellaard, R., van der Flier, W. M., Kloet, R. W., van der Doef, T. F., Knol, D. L., Windhorst, A. D., Luurtsema, G., Barkhof, F., et al. (2012) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2012.04.021 · Cited by 175

In vivo changes in microglial activation and amyloid deposits in brain regions with hypometabolism in Alzheimer’s disease

Yokokura, M., Mori, N., Yagi, S., Yoshikawa, E., Kikuchi, M., Yoshihara, Y., Wakuda, T., Sugihara, G., Takebayashi, K., Suda, S., et al. (2011) · European Journal of Nuclear Medicine and Molecular Imaging · doi:10.1007/s00259-010-1612-0 · Cited by 174

O1–03–01: Microglial activation in patients with mild cognitive impairment and Alzheimer's disease: A study using [11C](R)–PK11195 and PET

Schuitemaker, A., van Berckel, B. N. M., Boellaard, R., Kropholler, M. A., Lubberink, M., Jonker, C., Lammertsma, A. A., & Scheltens, P. (2006) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2006.05.044

Microglial activation and amyloid deposition in mild cognitive impairment: A PET study

Okello, A., Edison, P., Archer, H. A., Turkheimer, F. E., Kennedy, J., Bullock, R., Walker, Z., Kennedy, A., Fox, N., Rossor, M., et al. (2009) · Neurology · doi:10.1212/01.wnl.0000338622.27876.0d · Cited by 367