The DOI matches its Crossref record; 243 of the 243 references it cites were found in a registry or an index.
Physical exercise as an epigenetic modulator of brain plasticity and cognition
Open accessAbstract
A large amount of evidence has demonstrated the power of exercise to support cognitive function, the effects of which can last for considerable time. An emerging line of scientific evidence indicates that the effects of exercise are longer lasting than previously thought up to the point to affect future generations. The action of exercise on epigenetic regulation of gene expression seem central to building an “epigenetic memory” to influence long-term brain function and behavior. In this review article, we discuss new developments in the epigenetic field connecting exercise with changes in cognitive function, including DNA methylation, histone modifications and microRNAs (miRNAs). The understanding of how exercise promotes long-term cognitive effects is crucial for directing the power of exercise to reduce the burden of neurological and psychiatric disorders.
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Cited by
Mandolesi, L., Polverino, A., Montuori, S., Foti, F., Ferraioli, G., Sorrentino, P., & Sorrentino, G. (2018) · Frontiers in Psychology · doi:10.3389/fpsyg.2018.00509 · Cited by 1,038
Schiele, M. A., Gottschalk, M. G., & Domschke, K. (2020) · Clinical Psychology Review · doi:10.1016/j.cpr.2020.101830 · Cited by 156
Jiménez-Maldonado, A., Rentería, I., García-Suárez, P. C., Moncada-Jiménez, J., & Freire-Royes, L. F. (2018) · Frontiers in Neuroscience · doi:10.3389/fnins.2018.00839 · Cited by 118
Physical Exercise Prevented Stress‐Induced Anxiety via Improving Brain RNA Methylation
Yan, L., Wei, J., Yang, F., Wang, M., Wang, S., Cheng, T., Liu, X., Jia, Y., So, K., & Zhang, L. (2022) · Advanced Science · doi:10.1002/advs.202105731 · Cited by 83
Dysfunction of Glutamatergic Synaptic Transmission in Depression: Focus on AMPA Receptor Trafficking
He, J.-G., Zhou, H.-Y., Wang, F., & Chen, J.-G. (2023) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2022.02.007 · Cited by 36
Metadata
- Authors
- Fernandes, J., Arida, R. M., & Gomez-Pinilla, F.
- Venue
- Neuroscience & Biobehavioral Reviews
- Publisher
- Elsevier BV
- Published
- 2017-09
- Volume
- 80
- Pages
- 443-456
- ISSN
- 0149-7634 (ISSN-L)
- OpenAlex
- W2732794682
- Cited by
- 320
- References
- 243
- FWCI
- 7.57
- Type
- journal article
- Language
- en
- Open access
- green
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- Funders
- National Institutes of Health (NS50465)
- Fundação de Amparo à Pesquisa do Estado de São Paulo (2013/12692-4, 2013/13725-3, 2015/09234-0)
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (300605/2013-07)
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- Fernandes, J., Arida, R. M., & Gomez-Pinilla, F. (2017). Physical exercise as an epigenetic modulator of brain plasticity and cognition. Neuroscience & Biobehavioral Reviews. https://doi.org/10.1016/j.neubiorev.2017.06.012
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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