GLAST (GLutamate and ASpartate transporter) in human prefrontal cortex; interactome in healthy brains and the expression of GLAST in brains of chronic alcoholics

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

Bradford, M. M. (1976) · Analytical Biochemistry · doi:10.1016/0003-2697(76)90527-3 · Cited by 255,302 · see citing works

Diagnostic and Statistical Manual of Mental Disorders

American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works

Diagnostic and Statistical Manual of Mental Disorders

Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works

Glutamate: A Neurotransmitter in Mammalian Brain

Fonnum, F. (1984) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.1984.tb09689.x · Cited by 2,003 · see citing works

Glutamate as a neurotransmitter in the healthy brain

Zhou, Y., & Danbolt, N. C. (2014) · Journal of Neural Transmission · doi:10.1007/s00702-014-1180-8 · Cited by 989 · see citing works

Chronic Glutamate Toxicity in Neurodegenerative Diseases—What is the Evidence?

Lewerenz, J., & Maher, P. A. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00469 · Cited by 721 · see citing works

Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior

Spanagel, R. (2009) · Physiological Reviews · doi:10.1152/physrev.00013.2008 · Cited by 636 · see citing works

The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption

Spanagel, R., Pendyala, G., Abarca, C., Zghoul, T., Sanchis-Segura, C., Magnone, M. C., Lascorz, J., Depner, M., Holzberg, D., Soyka, M., et al. (2005) · Nature Medicine · doi:10.1038/nm1163 · Cited by 594 · see citing works

The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention

Sheldon, A. L., & Robinson, M. B. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.03.012 · Cited by 593 · see citing works

Human alcohol-related neuropathology

de la Monte, S. M., & Kril, J. J. (2014) · Acta Neuropathologica · doi:10.1007/s00401-013-1233-3 · Cited by 416 · see citing works

The glutamatergic basis of human alcoholism

Tsai, G. E., Gastfriend, D. R., & COYLE, J. T. (1995) · American Journal of Psychiatry · doi:10.1176/ajp.152.3.332 · Cited by 385 · see citing works

GABA and Glutamate Transporters in Brain

Zhou, Y., & Danbolt, N. C. (2013) · Frontiers in Endocrinology · doi:10.3389/fendo.2013.00165 · Cited by 347 · see citing works

Human prefrontal cortex

Teffer, K., & Semendeferi, K. (2012) · Progress in brain research · doi:10.1016/b978-0-444-53860-4.00009-x · Cited by 345 · see citing works

Long‐lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol

Rimondini, R., Arlinde, C., Sommer, W. H., & Heilig, M. A. (2002) · The FASEB Journal · doi:10.1096/fj.01-0593com · Cited by 320 · see citing works

Quality control parameters on a large dataset of regionally dissected human control brains for whole genome expression studies

Trabzuni, D., Ryten, M., Walker, R., Smith, C., Imran, S., Ramasamy, A., Weale, M. E., & Hardy, J. (2011) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2011.07432.x · Cited by 229 · cited 1× · see citing works

Glutamate-mediated transmission, alcohol, and alcoholism

Dodd, P. R., Beckmann, A. M., Davidson, M. S., & Wilce, P. A. (2000) · Neurochemistry International · doi:10.1016/s0197-0186(00)00061-9 · Cited by 214 · see citing works

Neuronal vs glial glutamate uptake: Resolving the conundrum

Danbolt, N. C., Furness, D. N., & Zhou, Y. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.05.009 · Cited by 214 · see citing works

Glutamate Uptake Stimulates Na+,K+‐ATPase Activity in Astrocytes via Activation of a Distinct Subunit Highly Sensitive to Ouabain

Pellerin, L., & Magistretti, P. J. (1997) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.1997.69052132.x · Cited by 210 · see citing works

Ethanol Exposure Decreases Glutamate Uptake in the Nucleus Accumbens

Meléndez, R. I., Hicks, M. P., Cagle, S., & Kalivas, P. W. (2005) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000156086.65665.4d · Cited by 192 · see citing works

Astroglial glutamate transporters coordinate excitatory signaling and brain energetics

Robinson, M. B., & Jackson, J. G. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.03.014 · Cited by 144 · see citing works

Cytoskeletal Anchoring of GLAST Determines Susceptibility to Brain Damage

Sullivan, S. M., Lee, A., Björkman, S. T., Miller, S. M., Sullivan, R. K. P., Poronnik, P., Colditz, P. B., & Pow, D. V. (2007) · Journal of Biological Chemistry · doi:10.1074/jbc.m704152200 · Cited by 128 · see citing works

The glutamate transporter, GLAST, participates in a macromolecular complex that supports glutamate metabolism

Bauer, D., Jackson, J. G., Genda, E. N., Montoya, M. M., Yudkoff, M., & Robinson, M. B. (2012) · Neurochemistry International · doi:10.1016/j.neuint.2012.01.013 · Cited by 116 · see citing works

Impact of Alcohol Abuse on Protein Expression of Midkine and Excitatory Amino Acid Transporter 1 in the Human Prefrontal Cortex

Flatscher‐Bader, T., & Wilce, P. A. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00754.x · Cited by 73 · see citing works

Rottlerin, an inhibitor of protein kinase Cδ (PKCδ), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKCδ‐independent

Susarla, B. T. S., & Robinson, M. B. (2003) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2003.01886.x · Cited by 62 · see citing works

Forty years of amino acid transmission in the brain

Bennett, M. R., & Balcar, V. J. (1999) · Neurochemistry International · doi:10.1016/s0197-0186(99)00068-6 · Cited by 54 · see citing works

Viruses and the immune system: their roles in seizure cascade development

Getts, D. R., Balcar, V. J., Matsumoto, I., et al. (2007) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2007.05171.x · Cited by 54 · see citing works

GLAST But Not Least—Distribution, Function, Genetics and Epigenetics of l-Glutamate Transport in Brain—Focus on GLAST/EAAT1

Šerý, O., Sultana, N., Kashem, M. A., Pow, D. V., & Balcar, V. J. (2015) · Neurochemical Research · doi:10.1007/s11064-015-1605-2 · Cited by 52 · see citing works

Differential regulation of GLAST immunoreactivity and activity by protein kinase C: evidence for modification of amino and carboxyl termini

Susarla, B. T. S., Seal, R. P., Zelenaia, O. A., et al. (2004) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2004.02791.x · Cited by 49 · see citing works

Proteomic Analysis Demonstrates Adolescent Vulnerability to Lasting Hippocampal Changes Following Chronic Alcohol Consumption

Hargreaves, G. A., Quinn, H., Kashem, M. A., Matsumoto, I., & McGregor, I. S. (2008) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.2008.00814.x · Cited by 49 · see citing works

Differential protein expression in the corpus callosum (splenium) of human alcoholics: A proteomics study

Kashem, M. A., James, G., Harper, C. G., Wilce, P. A., & Matsumoto, I. (2006) · Neurochemistry International · doi:10.1016/j.neuint.2006.10.009 · Cited by 49 · see citing works

Differential protein expression profiles in the hippocampus of human alcoholics

Matsuda-Matsumoto, H., Iwazaki, T., Kashem, M. A., Harper, C., & Matsumoto, I. (2007) · Neurochemistry International · doi:10.1016/j.neuint.2007.04.001 · Cited by 49 · see citing works

Reduced alcohol intake and reward associated with impaired endocannabinoid signaling in mice with a deletion of the glutamate transporter GLAST

Karlsson, R.-M., Adermark, L., Molander, A., Perreau-Lenz, S., Singley, E., Solomon, M., Holmes, A., Tanaka, K., Lovinger, D. M., Spanagel, R., et al. (2012) · Neuropharmacology · doi:10.1016/j.neuropharm.2012.01.027 · Cited by 44 · see citing works

Rapid loss of glutamine synthetase from astrocytes in response to hypoxia: Implications for excitotoxicity

Lee, A., Lingwood, B. E., Bjorkman, S. T., et al. (2009) · Journal of Chemical Neuroanatomy · doi:10.1016/j.jchemneu.2009.12.002 · Cited by 41 · see citing works

Links between l-glutamate transporters, Na+/K+-ATPase and cytoskeleton in astrocytes: Evidence following inhibition with rottlerin

Sheean, R. K., Lau, C. L., Shin, Y. S., et al. (2013) · Neuroscience · doi:10.1016/j.neuroscience.2013.09.043 · Cited by 39 · see citing works

Differential protein expression in the corpus callosum (genu) of human alcoholics

Kashem, M. A., Harper, C. G., & Matsumoto, I. (2008) · Neurochemistry International · doi:10.1016/j.neuint.2008.04.003 · Cited by 37 · see citing works

Molecular Pharmacology of the Na+-Dependent Transport of Acidic Amino Acids in the Mammalian Central Nervous System.

Balcar, V. J. (2002) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.25.291 · Cited by 34 · see citing works

Long-term daily access to alcohol alters dopamine-related synthesis and signaling proteins in the rat striatum

Kashem, M. A., Ahmed, S., Sarker, R., Ahmed, E. U., Hargreaves, G. A., & McGregor, I. S. (2012) · Neurochemistry International · doi:10.1016/j.neuint.2012.08.013 · Cited by 32 · see citing works

GABA a receptor α‐subunit proteins in human chronic alcoholics

Lewohl, J. M., Huygens, F., Crane, D. I., & Dodd, P. R. (2001) · Journal of Neurochemistry · doi:10.1046/j.1471-4159.2001.00414.x · Cited by 28 · see citing works

Extended post-mortem delay times should not be viewed as a deterrent to the scientific investigation of human brain tissue: a study from the Brains for Dementia Research Network Neuropathology Study Group, UK

Robinson, A., Palmer, L., Love, S., Hamard, M., Esiri, M. M., Ansorge, O., Lett, D. J., Attems, J., Morris, C. M., Troakes, C., et al. (2016) · Acta Neuropathologica · doi:10.1007/s00401-016-1617-2 · Cited by 27 · see citing works

Ethanol, not detectably metabolized in brain, significantly reduces brain metabolism, probably via action at specific GABA (A) receptors and has measureable metabolic effects at very low concentrations

Rae, C. D., Davidson, J. E., Maher, A. D., Rowlands, B. D., Kashem, M. A., Nasrallah, F. A., Rallapalli, S., Cook, J. M., & Balcar, V. J. (2013) · Journal of Neurochemistry · doi:10.1111/jnc.12634 · Cited by 26 · see citing works

Distribution of Glutamate Transporter GLAST in Membranes of Cultured Astrocytes in the Presence of Glutamate Transport Substrates and ATP

Shin, J., Nguyen, K. T. D., Pow, D. V., et al. (2009) · Neurochemical Research · doi:10.1007/s11064-009-9982-z · Cited by 26 · see citing works

Metabolomics of Neurotransmitters and Related Metabolites in Post-Mortem Tissue from the Dorsal and Ventral Striatum of Alcoholic Human Brain

Kashem, M. A., Ahmed, S., Sultana, N., Ahmed, E. U., Pickford, R., Rae, C. D., Šerý, O., McGregor, I. S., & Balcar, V. J. (2016) · Neurochemical Research · doi:10.1007/s11064-016-1830-3 · Cited by 24 · see citing works

A long hangover from party drugs: Residual proteomic changes in the hippocampus of rats 8 weeks after γ-hydroxybutyrate (GHB), 3,4-methylenedioxymethamphetamine (MDMA) or their combination

Nieuwenhuijzen, P. S. V., Kashem, M. A., Matsumoto, I., Hunt, G. E., & McGregor, I. S. (2010) · Neurochemistry International · doi:10.1016/j.neuint.2010.03.002 · Cited by 22 · see citing works

EFFECTS OF GLUTAMATE TRANSPORT SUBSTRATES AND GLUTAMATE RECEPTOR LIGANDS ON THE ACTIVITY OF Na+/K+‐ATPase IN BRAIN TISSUE IN VITRO

Nanitsos, E. K., Acosta, G. B., Saihara, Y., et al. (2004) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2004.04090.x · Cited by 21 · see citing works

Effects of typical (haloperidol) and atypical (risperidone) antipsychotic agents on protein expression in rat neural stem cells

Kashem, M. A., Ummehany, R., Ukai, W., Hashimoto, E., Saito, T., McGregor, I. S., & Matsumoto, I. (2009) · Neurochemistry International · doi:10.1016/j.neuint.2009.05.007 · Cited by 21 · see citing works

Differential protein expression in the corpus callosum (body) of human alcoholic brain

Kashem, M. A., Etages, H. D., Kopitar‐Jerala, N., McGregor, I. S., & Matsumoto, I. (2009) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2009.06141.x · Cited by 21 · see citing works

Excitatory Amino Acid Transporter 5 is widely expressed in peripheral tissues

Lee, A., Anderson, A. R., Stevens, M., et al. (2013) · European Journal of Histochemistry · doi:10.4081/ejh.2013.e11 · Cited by 20 · see citing works

Cardiac Glycosides Ouabain and Digoxin Interfere with the Regulation of Glutamate Transporter GLAST in Astrocytes Cultured from Neonatal Rat Brain

Nguyen, K. T. D., Buljan, V. A., Else, P. L., et al. (2010) · Neurochemical Research · doi:10.1007/s11064-010-0274-4 · Cited by 20 · see citing works

Alternate splicing and expression of the glutamate transporter EAAT5 in the rat retina

Lee, A., Anderson, A. R., Barnett, N. L., et al. (2012) · Gene · doi:10.1016/j.gene.2012.07.010 · Cited by 19 · see citing works

Rottlerin Inhibits (Na+, K+)-ATPase Activity in Brain Tissue and Alters d-Aspartate Dependent Redistribution of Glutamate Transporter GLAST in Cultured Astrocytes

Nguyen, K. T. D., Shin, J., Rae, C. D., et al. (2009) · Neurochemical Research · doi:10.1007/s11064-009-9996-6 · Cited by 10 · see citing works

Intermittent Hypercapnic Hypoxia Induced Protein Changes in the Piglet Hippocampus Identified by MALDI-TOF-MS

Tang, S., Machaalani, R., Kashem, M. A., et al. (2009) · Neurochemical Research · doi:10.1007/s11064-009-0021-x · Cited by 9 · see citing works

Exposure of Rat Neural Stem Cells to Ethanol Affects Cell Numbers and Alters Expression of 28 Proteins

Kashem, M. A., Sultana, N., & Balcar, V. J. (2018) · Neurochemical Research · doi:10.1007/s11064-018-2600-1 · Cited by 9 · see citing works

A novel splice variant of the Excitatory Amino Acid Transporter 5: Cloning, immunolocalization and functional characterization of hEAAT5v in human retina

Lee, A., Stevens, M. G., Anderson, A. R., et al. (2016) · Neurochemistry International · doi:10.1016/j.neuint.2016.10.013 · Cited by 7 · see citing works

Single cell transcriptome profiling of the human alcohol-dependent brain

Brenner, E., Tiwari, G. R., Kapoor, M., Liu, Y., Brock, A., & Mayfield, R. D. (2020) · Human Molecular Genetics · doi:10.1093/hmg/ddaa038 · Cited by 118 · see citing works

Illuminating the dark protein-protein interactome

Tabar, M. S., Parsania, C., Chen, H., Su, X., Bailey, C. G., & Rasko, J. E. J. (2022) · Cell Reports Methods · doi:10.1016/j.crmeth.2022.100275 · Cited by 43 · see citing works

Estimating dispensable content in the human interactome

Ghadie, M. A., & Xia, Y. (2019) · Nature Communications · doi:10.1038/s41467-019-11180-2 · Cited by 17 · see citing works

Plant Protein-Protein Interaction Network and Interactome

Zhang, Y., Gao, P., & Yuan, J. S. (2009) · Current Genomics · doi:10.2174/138920210790218016 · Cited by 131 · see citing works

The social architecture of an in-depth cellular protein interactome

Michaelis, A. C., Brunner, A.-D., Zwiebel, M., Meier, F., Strauss, M. T., Bludau, I., & Mann, M. (2021) · doi:10.1101/2021.10.24.465633 · Cited by 119 · see citing works

The C. elegans Interactome: Its Generation and Visualization

Chesnau, A., & Sardet, C. (2005) · doi:10.1002/0470094419.ch8