Alzheimer's disease neuropathologic change, Lewy body disease, and vascular brain injury in clinic- and community-based samples
Open accessAbstract
We examined the relationships between Alzheimer's disease neuropathologic change (ADNC), Lewy body disease (LBD), and vascular brain injury (VBI) in 2 large autopsy samples. Because findings may differ between study populations, data came from U.S. Alzheimer's Disease Centers contributing to the National Alzheimer's Coordinating Center (n = 2742) and from the population-based Adult Changes in Thought study (n = 499). Regardless of study population, over 50% of participants with ADNC had co-occurring LBD or VBI; the majority of whom had a clinical AD dementia diagnosis prior to death. Overlap of pathologies was similar between studies, especially after standardizing to the distribution of age and dementia status in the Adult Changes in Thought population. LBD, but not VBI, was positively associated with ADNC in both studies. Interestingly, cortical LBD was more common in those with intermediate ADNC compared to low or high ADNC, especially in the National Alzheimer's Coordinating Center (p < 0.001). High prevalence of co-occurring neuropathologies among older adults with dementia has implications for accurate diagnosis of dementia etiologies and development of disease-modifying strategies.
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A study examined difference between NACC and ACT and found that, while there was more vascular pathology in ACT participants, they were also older.
“A study examined the difference between NACC and ACT and found that, while there was more vascular pathology in ACT participants, they were also older.”
From Concordance of Clinical Alzheimer Diagnosis and Neuropathological Features at Autopsy (2020) · cites this paper as [18]
The Results (§3.1; page not available in our copy) report that autopsied ACT participants with dementia were older at death and had more vascular brain injury than their NACC counterparts. The claim omits that this finding concerns participants with dementia; the paper says participants without dementia were relatively similar in demographic and pathologic characteristics. (LLM, conf=0.88)
Experimental — accuracy not yet measuredClinic-based participants differ from community-based studies, for example, the amount, type, and distribution of neuropathologic changes differ by the source of a participant.
“It is widely recognized that clinic-based participants differ from community-based studies, for example, the amount, type, and distribution of neuropathologic changes differ by the source of a participant [206,207].”
From NIA‐AA Research Framework: Toward a biological definition of Alzheimer's disease (2018) · cites this paper as [207]
Over 50% of participants with ADNC had cooccurring LBD pathology or vascular brain injury.
“Another study found that over 50% of participants with ADNC had cooccurring LBD pathology or vascular brain injury (18).”
From Concordance of Clinical Alzheimer Diagnosis and Neuropathological Features at Autopsy (2020) · cites this paper as [18]
Mixed pathologies were common in both populations, and once age distribution was accounted for, distribution of mixed pathologies among NACC and ACT participants was similar, with AD+LBD and AD+Vascular Brain Injury being the most common mixed pathologies.
“Mixed pathologies were common in both populations, and once the age distribution was accounted for the distribution of mixed pathologies among NACC participants and ACT participants was similar, with ADþ LBD and ADþVascular Brain Injury being the most common mixed pathologies in those populations (18).”
From Concordance of Clinical Alzheimer Diagnosis and Neuropathological Features at Autopsy (2020) · cites this paper as [18]
Cognitive trajectories were similar between participants with mixed pathologies and participants who only had ADNC; impact of co-occurring pathologies may have been due to severity of AD more than mixed pathologies.
“Other studies found that cognitive trajectories were similar between participants with mixed pathologies and participants who only had ADNC; though, the impact of co-occurring pathologies may have been due to the severity of AD more than the mixed pathologies (18,19).”
From Concordance of Clinical Alzheimer Diagnosis and Neuropathological Features at Autopsy (2020) · cites this paper as [18]
The Results (§3.3; page unavailable) compare clinical characteristics of participants with ADNC only and mixed ADNC, but do not report cognitive trajectories. The Discussion (§4; page unavailable) addresses co-occurring pathologies and ADNC levels, not whether AD severity explains their cognitive impact. Searches for cognitive trajectories and AD severity found no passage establishing either part of the claim. (LLM, conf=0.74)
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Cites
R: A Language and Environment for Statistical Computing
R Core Team (2000) · doi:10.32614/r.manuals · Cited by 355,706 · see citing works
McKhann, G., Drachman, D., Folstein, M., Katzman, R., Price, D., & Stadlan, E. M. (1984) · Neurology · doi:10.1212/wnl.34.7.939 · Cited by 27,915 · see citing works
Spillantini, M. G., Schmidt, M. L., Lee, V. M.-Y., Trojanowski, J. Q., Jakes, R., & Goedert, M. (1997) · Nature · doi:10.1038/42166 · Cited by 8,382 · see citing works
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
Neumann, M., Sampathu, D. M., Kwong, L. K., Truax, A. C., Micsenyi, M. C., Chou, T. T., Bruce, J., Schuck, T., Grossman, M., Clark, C. M., et al. (2006) · Science · doi:10.1126/science.1134108 · Cited by 6,576 · see citing works
Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium
McKeith, I. G., Dickson, D. W., Lowe, J., Emre, M., O'Brien, J. T., Feldman, H., Cummings, J., Duda, J. E., Lippa, C., Perry, E. K., et al. (2005) · Neurology · doi:10.1212/01.wnl.0000187889.17253.b1 · Cited by 5,069 · see citing works
Mirra, S. S., Heyman, A., McKeel, D., Sumi, S. M., Crain, B. J., Brownlee, L. M., Vogel, F. S., Hughes, J. P., Belle, G. V., Berg, L., et al. (1991) · Neurology · doi:10.1212/wnl.41.4.479 · Cited by 4,961 · see citing works
Gorelick, P. B., Scuteri, A., Black, S. E., DeCarli, C., Greenberg, S. M., Iadecola, C., Launer, L. J., Laurent, S., Lopez, O. L., Nyenhuis, D., et al. (2011) · Stroke · doi:10.1161/str.0b013e3182299496 · Cited by 3,811 · cited 2× · see citing works
“A higher proportion of participants with ADNC and co-occurring VBI were male and had a history of stroke compared to ADNC only, characteristics associated with VBI in general (Gorelick et al., 2011; Jellinger, 2013).”
Phases of Aβ-deposition in the human brain and its relevance for the development of AD
Thal, D. R., Rüb, U., Orantes, M., & Braak, H. (2002) · Neurology · doi:10.1212/wnl.58.12.1791 · Cited by 3,490 · see citing works
Braak, H., Alafuzoff, I., Arzberger, T., Kretzschmar, H., & Del Tredici, K. (2006) · Acta Neuropathologica · doi:10.1007/s00401-006-0127-z · Cited by 3,172 · see citing works
Hyman, B. T., Phelps, C. H., Beach, T. G., Bigio, E. H., Cairns, N. J., Carrillo, M. C., Dickson, D. W., Duyckaerts, C., Frosch, M. P., Masliah, E., et al. (2012) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2011.10.007 · Cited by 3,092 · see citing works
Mixed brain pathologies account for most dementia cases in community-dwelling older persons
Schneider, J. A., Arvanitakis, Z., Bang, W., & Bennett, D. A. (2007) · Neurology · doi:10.1212/01.wnl.0000271090.28148.24 · Cited by 1,992 · see citing works
Primary age-related tauopathy (PART): a common pathology associated with human aging
Crary, J. F., Trojanowski, J. Q., Schneider, J. A., Abisambra, J. F., Abner, E. L., Alafuzoff, I., Arnold, S. E., Attems, J., Beach, T. G., Bigio, E. H., et al. (2014) · Acta Neuropathologica · doi:10.1007/s00401-014-1349-0 · Cited by 1,467 · see citing works
Self-citationLarson, E. B., Wang, L., Bowen, J. D., McCormick, W. C., Teri, L., Crane, P., & Kukull, W. (2006) · Annals of Internal Medicine · doi:10.7326/0003-4819-144-2-200601170-00004 · Cited by 1,463 · see citing works
Self-citationMorris, J. C., Weintraub, S., Chui, H. C., Cummings, J., DeCarli, C., Ferris, S., Foster, N. L., Galasko, D., Graff-Radford, N., Peskind, E. R., et al. (2006) · Alzheimer Disease & Associated Disorders · doi:10.1097/01.wad.0000213865.09806.92 · Cited by 950 · see citing works
Self-citationGlucose Levels and Risk of Dementia
Crane, P. K., Walker, R., Hubbard, R. A., Li, G., Nathan, D. M., Zheng, H., Haneuse, S., Craft, S., Montine, T. J., Kahn, S. E., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1215740 · Cited by 929 · see citing works
Self-citationTeng, E. L., Hasegawa, K., Homma, A., Imai, Y., Larson, E. B., Graves, A. B., Sugimoto, K., Yamaguchi, T., Sasaki, H., Chiu, D., et al. (1994) · International Psychogeriatrics · doi:10.1017/s1041610294001602 · Cited by 910 · see citing works
Self-citationThe National Alzheimer's Coordinating Center (NACC) Database: The Uniform Data Set
Beekly, D. L., Ramos, E. M., Lee, W. W., Deitrich, W. D., Jacka, M. E., Wu, J., Hubbard, J. L., Koepsell, T. D., Morris, J. C., & Kukull, W. A. (2007) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0b013e318142774e · Cited by 907 · see citing works
Self-citationDementia and Alzheimer Disease Incidence: A Prospective Cohort Study
Kukull, W. A., Higdon, R., Bowen, J. D., McCormick, W. C., Teri, L., Schellenberg, G. D., van Belle, G., Jolley, L., & Larson, E. B. (2002) · Archives of Neurology · doi:10.1001/archneur.59.11.1737 · Cited by 806 · see citing works
Self-citationHamilton, R. L. (2000) · Brain Pathology · doi:10.1111/j.1750-3639.2000.tb00269.x · Cited by 754 · see citing works
eulerAPE: Drawing Area-Proportional 3-Venn Diagrams Using Ellipses
Micallef, L., & Rodgers, P. J. (2014) · PLoS ONE · doi:10.1371/journal.pone.0101717 · Cited by 493 · see citing works
Clinico‐Neuropathological Correlation of Alzheimer's Disease in a Community‐Based Case Series
Lim, A., Tsuang, D. W., Kukull, W. A., Nochlin, D., Leverenz, J. B., McCormick, W. C., Bowen, J., Teri, L. L., Thompson, J. C., Peskind, E. R., et al. (1999) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1999.tb02571.x · Cited by 450 · see citing works
Self-citationPathological correlates of dementia in a longitudinal, population‐based sample of aging
Sonnen, J. A., Larson, E. B., Crane, P. K., Haneuse, S., Li, G., Schellenberg, G. D., Craft, S., Leverenz, J. B., & Montine, T. J. (2007) · Annals of Neurology · doi:10.1002/ana.21208 · Cited by 432 · see citing works
Self-citationThe Neuropathology of Older Persons with and Without Dementia from Community versus Clinic Cohorts
Schneider, J. A., Aggarwal, N. T., Barnes, L., Boyle, P., & Bennett, D. A. (2009) · Journal of Alzheimer's Disease · doi:10.3233/jad-2009-1227 · Cited by 372 · see citing works
Prevalence of mixed pathologies in the aging brain
Rahimi, J., & Kovács, G. G. (2014) · Alzheimer s Research & Therapy · doi:10.1186/s13195-014-0082-1 · Cited by 365 · see citing works
Cerebrovascular Pathology and Dementia in Autopsied Honolulu‐Asia Aging Study Participants
WHITE, L., PETROVITCH, H., HARDMAN, J., NELSON, J., DAVIS, D. G., ROSS, G. W., MASAKI, K., LAUNER, L., & MARKESBERY, W. R. (2002) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2002.tb04794.x · Cited by 357 · see citing works
Pathology and pathogenesis of vascular cognitive impairment—a critical update
Jellinger, K. A. (2013) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2013.00017 · Cited by 353 · cited 1× · see citing works
“A higher proportion of participants with ADNC and co-occurring VBI were male and had a history of stroke compared to ADNC only, characteristics associated with VBI in general (Gorelick et al., 2011; Jellinger, 2013).”
BackgroundThe National Alzheimer's Coordinating Center (NACC) Database: an Alzheimer disease database.
Beekly, D. L., Ramos, E. M., van Belle, G., Deitrich, W. D., Clark, A. D., Jacka, M. E., & Kukull, W. A. (2004) · PubMed · Cited by 345 · see citing works
Self-citationMultiple pathologies are common and related to dementia in the oldest-old: The 90+ Study
Kawas, C. H., Kim, R. C., Sonnen, J. A., Bullain, S. S., Trieu, T., & Corrada, M. M. (2015) · Neurology · doi:10.1212/wnl.0000000000001831 · Cited by 303 · see citing works
Vascular and amyloid pathologies are independent predictors of cognitive decline in normal elderly
Vemuri, P., Lesnick, T. G., Przybelski, S. A., Knopman, D. S., Preboske, G. M., Kantarci, K., Raman, M. R., Machulda, M. M., Mielke, M. M., Lowe, V. J., et al. (2015) · Brain · doi:10.1093/brain/awu393 · Cited by 299 · see citing works
Kaye, J. A., Maxwell, S. A., Mattek, N., Hayes, T. L., Dodge, H. H., Misha Pavel, C., Jimison, H. B., Wild, K., Boise, L., & Zitzelberger, T. (2011) · The Journals of Gerontology Series B · doi:10.1093/geronb/gbq095 · Cited by 296 · see citing works
Prevalence of dementia disorders in the oldest-old: an autopsy study
Jellinger, K. A., & Attems, J. (2010) · Acta Neuropathologica · doi:10.1007/s00401-010-0654-5 · Cited by 276 · see citing works
Cognitive impairment, decline and fluctuations in older community-dwelling subjects with Lewy bodies
Schneider, J. A., Arvanitakis, Z., Yu, L., Boyle, P. A., Leurgans, S. E., & Bennett, D. A. (2012) · Brain · doi:10.1093/brain/aws234 · Cited by 273 · see citing works
Prevalence and impact of vascular and Alzheimer pathologies in Lewy body disease
Jellinger, K. A., & Attems, J. (2008) · Acta Neuropathologica · doi:10.1007/s00401-008-0347-5 · Cited by 265 · see citing works
Nelson, P. T., Abner, E. L., Schmitt, F. A., Kryscio, R. J., Jicha, G. A., Smith, C. D., Davis, D. G., Poduska, J. W., Patel, E., Mendiondo, M. S., et al. (2010) · Brain Pathology · doi:10.1111/j.1750-3639.2008.00244.x · Cited by 239 · see citing works
The Effects of Additional Pathology on the Cognitive Deficit in Alzheimer Disease
Nagy, Z., Esiri, M. M., Jobst, K. A., Morris, J. H., King, E. M.-F., McDonald, B., Joachim, C. L., Litchfield, S., Barnetson, L. P. D., & Smith, A. D. (1997) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/00005072-199702000-00007 · Cited by 218 · see citing works
Dementia From Alzheimer Disease and Mixed Pathologies in the Oldest Old
James, B. D. (2012) · JAMA · doi:10.1001/jama.2012.3556 · Cited by 199 · see citing works
Pathologic Accumulation of α-Synuclein and Aβ in Parkinson Disease Patients With Dementia
Kotzbauer, P. T., Cairns, N. J., Campbell, M. C., Willis, A. W., Racette, B. A., Tabbal, S. D., & Perlmutter, J. S. (2012) · Archives of Neurology · doi:10.1001/archneurol.2012.1608 · Cited by 197 · see citing works
Hippocampal sclerosis of aging, a prevalent and high-morbidity brain disease
Nelson, P. T., Smith, C. D., Abner, E. L., Wilfred, B. R., Wang, W., Neltner, J. H., Baker, M., Fardo, D. W., Kryscio, R. J., Scheff, S. W., et al. (2013) · Acta Neuropathologica · doi:10.1007/s00401-013-1154-1 · Cited by 196 · see citing works
Ecology of the Aging Human Brain
Sonnen, J. A. (2011) · Archives of Neurology · doi:10.1001/archneurol.2011.157 · Cited by 174 · cited 3× · see citing works
“However, other studies have found no relationship between VBI and amyloid burden (Sonnen et al., 2011; Vemuri et al., 2015).”
BackgroundResultNeuropathologic comorbidity and cognitive impairment in the Nun and Honolulu-Asia Aging Studies
White, L. R., Edland, S. D., Hemmy, L. S., Montine, K. S., Zarow, C., Sonnen, J. A., Uyehara‐Lock, J. H., Gelber, R. P., Ross, G. W., Petrovitch, H., et al. (2016) · Neurology · doi:10.1212/wnl.0000000000002480 · Cited by 171 · see citing works
“New Old Pathologies”: AD, PART, and Cerebral Age-Related TDP-43 With Sclerosis (CARTS)
Nelson, P. T., Trojanowski, J. Q., Abner, E. L., Al-Janabi, O. M., Jicha, G. A., Schmitt, F. A., Smith, C. D., Fardo, D. W., Wang, W.-X., Kryscio, R. J., et al. (2016) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlw033 · Cited by 158 · see citing works
Self-citationPrevalence and pathogenic role of cerebrovascular lesions in Alzheimer disease
Jellinger, K. A., & Attems, J. (2004) · Journal of the Neurological Sciences · doi:10.1016/j.jns.2004.11.018 · Cited by 143 · see citing works
Neurologic function in the optimally healthy oldest old
Howieson, D. B., Holm, L. A., Kaye, J. A., Oken, B., & Howieson, J. L. (1993) · Neurology · doi:10.1212/wnl.43.10.1882 · Cited by 142 · see citing works
Jellinger, K. A. (2007) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2006.09.002 · Cited by 139 · see citing works
Clinical Features of Alzheimer Disease With and Without Lewy Bodies
Chung, E. J., Babulal, G. M., Monsell, S. E., Cairns, N. J., Roe, C. M., & Morris, J. C. (2015) · JAMA Neurology · doi:10.1001/jamaneurol.2015.0606 · Cited by 126 · see citing works
Petersen, J. M., Austin, D., Mattek, N., & Kaye, J. A. (2015) · PLoS ONE · doi:10.1371/journal.pone.0139643 · Cited by 111 · see citing works
Effect of Vascular Lesions on Cognition in Alzheimer's Disease: A Community‐Based Study
Riekse, R. G., Leverenz, J. B., McCormick, W. C., Bowen, J. D., Teri, L. L., Nochlin, D., Simpson, K., Eugenio, C. J., Larson, E. B., & Tsuang, D. W. (2004) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2004.52405.x · Cited by 109 · see citing works
Self-citationBrenowitz, W. D., Monsell, S. E., Schmitt, F. A., Kukull, W. A., & Nelson, P. T. (2014) · Journal of Alzheimer's Disease · doi:10.3233/jad-131880 · Cited by 108 · see citing works
Self-citationHaneuse, S., Schildcrout, J. S., Crane, P. K., Sonnen, J. A., Breitner, J. C. S., & Larson, E. B. (2009) · Neuroepidemiology · doi:10.1159/000197389 · Cited by 106 · see citing works
Self-citationSerrano‐Pozo, A., Qian, J., Muzikansky, A., Monsell, S. E., Montine, T. J., Frosch, M. P., Betensky, R. A., & Hyman, B. T. (2016) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlw026 · Cited by 105 · see citing works
Swirski, M., Miners, J. S., de Silva, R., Lashley, T., Ling, H., Holton, J. L., Révész, T., & Love, S. (2014) · Alzheimer s Research & Therapy · doi:10.1186/s13195-014-0077-y · Cited by 97 · see citing works
Natural history of cognitive decline in the old old
Howieson, D. B., Camicioli, R. M., Quinn, J. F., Silbert, L. C., Care, B., Moore, M. M., Dame, A., Sexton, G. J., & Kaye, J. A. (2003) · Neurology · doi:10.1212/01.wnl.0000063317.44167.5c · Cited by 91 · see citing works
Obi, K., Akiyama, H., Kondo, H., Shimomura, Y., Hasegawa, M., Iwatsubo, T., Mizuno, Y., & Mochizuki, H. (2007) · Experimental Neurology · doi:10.1016/j.expneurol.2007.11.019 · Cited by 91 · see citing works
Dementia with Lewy bodies from the perspective of tauopathy
Iseki, E., Togo, T., Suzuki, K., Katsuse, O., Marui, W., de Silva, R., Lees, A. J., Yamamoto, T., & Kosaka, K. (2003) · Acta Neuropathologica · doi:10.1007/s00401-002-0644-3 · Cited by 70 · see citing works
Cortical microinfarcts in Alzheimer's disease and subcortical vascular dementia
Okamoto, Y., Ihara, M., Fujita, Y., Ito, H., Takahashi, R., & Tomimoto, H. (2009) · Neuroreport · doi:10.1097/wnr.0b013e32832d2e6a · Cited by 68 · see citing works
Montine, T. J., Sonnen, J. A., Montine, K. S., Crane, P. K., & Larson, E. B. (2012) · Current Alzheimer Research · doi:10.2174/156720512801322555 · Cited by 56 · see citing works
Self-citationA discriminant analysis extension to mixed models
Tomasko, L., Helms, R. W., & Snapinn, S. M. (1999) · Statistics in Medicine · doi:10.1002/(sici)1097-0258(19990530)18:10 · Cited by 55 · see citing works
Genetic association between the APOE * 4 allele and Lewy bodies in Alzheimer disease
Tsuang, D. W., Wilson, R. K., López, O. L., Luedecking‐Zimmer, E., Leverenz, J. B., DeKosky, S. T., Kamboh, M. I., & Hamilton, R. L. (2005) · Neurology · doi:10.1212/01.wnl.0000150892.81839.d1 · Cited by 50 · see citing works
Lewy body variant of Alzheimerʼs disease
Wirths, O., Weickert, S., Majtényi, K., Havas, L., Kahle, P. J., Okochi, M., Haass, C., Multhaup, G., Beyreuther, K. T., & Bayer, T. A. (2000) · Neuroreport · doi:10.1097/00001756-200011270-00029 · Cited by 48 · see citing works
Pathologic Correlates of Dementia in Individuals with Lewy Body Disease
Sonnen, J. A., Postupna, N. O., Larson, E. B., Crane, P. K., Rose, S. E., Montine, K. S., Leverenz, J. B., & Montine, T. J. (2010) · Brain Pathology · doi:10.1111/j.1750-3639.2009.00371.x · Cited by 42 · see citing works
Self-citationImportance of home study visit capacity in dementia studies
Crane, P. K., Gibbons, L. E., McCurry, S. M., McCormick, W. C., Bowen, J. D., Sonnen, J. A., Keene, C. D., Grabowski, T. J., Montine, T. J., & Larson, E. B. (2015) · Alzheimer s & Dementia · doi:10.1016/j.jalz.2015.10.007 · Cited by 34 · see citing works
Self-citationPostupna, N. O., Keene, C. D., Crane, P. K., Gonzalez‐Cuyar, L. F., Sonnen, J. A., Hewitt, J. L., Rice, S., Howard, K., Montine, K. S., Larson, E. B., et al. (2015) · Journal of Neuropathology & Experimental Neurology · doi:10.1097/nen.0000000000000153 · Cited by 21 · see citing works
Self-citationExceptional Brain Aging in a Rural Population‐Based Cohort
Kaye, J. A., Michael, Y., Calvert, J. F., Leahy, M., Crawford, D., & Kramer, P. (2009) · The Journal of Rural Health · doi:10.1111/j.1748-0361.2009.00237.x · Cited by 16 · see citing works
Flagged first, then by citations
Research works printed but not linked: 1
- Zhou XH Castelluccio P Hui SL Rodenberg CA Comparing two prevalence rates in a two-phase design study Stat. Med 1999 18 1171 1182 10363338
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Sorted by citations
NIA‐AA Research Framework: Toward a biological definition of Alzheimer's disease
Jack, C. R., Bennett, D. A., Blennow, K., Carrillo, M. C., Dunn, B., Haeberlein, S. B., Holtzman, D. M., Jagust, W., Jessen, F., Karlawish, J., et al. (2018) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2018.02.018 · Cited by 10,537 · see citing works
“It is widely recognized that clinic-based participants differ from community-based studies, for example, the amount, type, and distribution of neuropathologic changes differ by the source of a participant [206,207].”
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Arvanitakis, Z., Shah, R. C., & Bennett, D. A. (2019) · JAMA · doi:10.1001/jama.2019.4782 · Cited by 1,451 · see citing works
Gale, S. A., Acar, D., & Daffner, K. R. (2018) · The American Journal of Medicine · doi:10.1016/j.amjmed.2018.01.022 · Cited by 702 · see citing works
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Self-citationThe degree of frailty as a translational measure of health in aging
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Revisiting protein aggregation as pathogenic in sporadic Parkinson and Alzheimer diseases
Espay, A. J., Vizcarra, J. A., Marsili, L., Lang, A. E., Simon, D. K., Merola, A., Josephs, K. A., Fasano, A., Morgante, F., Savica, R., et al. (2019) · Neurology · doi:10.1212/wnl.0000000000006926 · Cited by 274 · see citing works
Hainsworth, A. H., Markus, H. S., & Schneider, J. A. (2023) · Hypertension · doi:10.1161/hypertensionaha.123.19943 · Cited by 271 · see citing works
Weuve, J., Bennett, E. E., Ranker, L., Gianattasio, K. Z., Pedde, M., Adar, S. D., Yanosky, J. D., & Power, M. C. (2021) · Environmental Health Perspectives · doi:10.1289/ehp8716 · Cited by 209 · see citing works
Burfeind, K. G., Murchison, C. F., Westaway, S. K., Simon, M. J., Erten‐Lyons, D., Kaye, J. A., Quinn, J. F., & Iliff, J. J. (2017) · Alzheimer's & Dementia: Translational Research & Clinical Interventions · doi:10.1016/j.trci.2017.05.001 · Cited by 136 · see citing works
Aging without Dementia is Achievable: Current Evidence from Epidemiological Research
Qiu, C., & Fratiglioni, L. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-171037 · Cited by 125 · see citing works
Arnold, M. R., Coughlin, D. G., Brumbach, B. H., Smirnov, D. S., Concha‐Marambio, L., Farris, C. M., Ma, Y., Kim, Y., Wilson, E. N., Kaye, J. A., et al. (2022) · Annals of Neurology · doi:10.1002/ana.26453 · Cited by 120 · see citing works
Self-citationHayden, M. R. (2019) · Brain Sciences · doi:10.3390/brainsci9100262 · Cited by 90 · see citing works
Pimavanserin: Potential Treatment For Dementia-Related Psychosis
Cummings, J. L., Ballard, C. G., Tariot, P. N., Owen, R., Foff, E. P., Youakim, J. M., Norton, J., & Stankovic, S. (2018) · The Journal of Prevention of Alzheimer s Disease · doi:10.14283/jpad.2018.29 · Cited by 89 · see citing works
Cummings, J. L., Pinto, L. C., de la Cruz, M. P., Fischer, C. E., Gerritsen, D. L., Grossberg, G. T., Hwang, T., Ismail, Z., Jeste, D. V., Koopmans, R. T. C. M., et al. (2020) · American Journal of Geriatric Psychiatry · doi:10.1016/j.jagp.2020.09.002 · Cited by 85 · see citing works
Alzheimer’s Disease Neuropathological Comorbidities are Common in the Younger-Old
Beach, T. G., & Malek‐Ahmadi, M. H. (2020) · Journal of Alzheimer s Disease · doi:10.3233/jad-201213 · Cited by 84 · see citing works
Spinocerebellar ataxia 27B: A novel, frequent and potentially treatable ataxia
Pellerin, D., Danzi, M. C., Renaud, M., Houlden, H., Synofzik, M., Zuchner, S. L., & Brais, B. (2024) · Clinical and Translational Medicine · doi:10.1002/ctm2.1504 · Cited by 82 · see citing works
Alzheimer’s/Vascular Spectrum Dementia: Classification in Addition to Diagnosis
Emrani, S., Lamar, M., Price, C. C., Wasserman, V., Matusz, E. F., Au, R., Swenson, R. A., Nagele, R. G., Heilman, K. M., & Libon, D. J. (2019) · Journal of Alzheimer s Disease · doi:10.3233/jad-190654 · Cited by 76 · see citing works
Induction of embryogenic competence in somatic plant cells: a review
Fehér, A., Pasternak, T. P., Ötvös, K., Miskolczi, P., & Dudits, D. (2002) · Cited by 67 · see citing works
Cognition at Each Stage of Lewy Body Disease with Co-occurring Alzheimer’s Disease Pathology
Ryman, S. G., Yutsis, M. V., Tian, L., Henderson, V. W., Montine, T. J., Salmon, D. P., Galasko, D. R., & Poston, K. L. (2021) · Journal of Alzheimer s Disease · doi:10.3233/jad-201187 · Cited by 60 · see citing works
Selvackadunco, S., Langford, K., Shah, Z., Hurley, S. M., Bódi, I., King, A., Aarsland, D., Troakes, C., & Al‐Sarraj, S. (2019) · Journal of Neural Transmission · doi:10.1007/s00702-018-01967-w · Cited by 58 · see citing works
Beach, T., Malek-Ahmadi, M., ZAMRINI, E. Y., Adler, C. H., Sabbagh, M. N., Shill, H. A., Jacobson, S. A., Belden, C. M., Caselli, R. J., Woodruff, B. K., et al. (2019) · PLoS ONE · doi:10.1371/journal.pone.0217566 · Cited by 56 · see citing works
Neuropathologic features associated with basal forebrain atrophy in Alzheimer disease
Teipel, S. J., Fritz, H.-C., Grothe, M. J., & Initiative, A. D. N. (2020) · Neurology · doi:10.1212/wnl.0000000000010192 · Cited by 56 · see citing works
McDade, E. (2022) · CONTINUUM Lifelong Learning in Neurology · doi:10.1212/con.0000000000001131 · Cited by 49 · see citing works
Alzheimer's disease neuropathology and its estimation with fluid and imaging biomarkers
Thal, D. R., Poesen, K., Vandenberghe, R. R., & Meyer, S. D. (2025) · Molecular Neurodegeneration · doi:10.1186/s13024-025-00819-y · Cited by 47 · see citing works
Lee, A., Raghavan, N. S., Bhattarai, P., Siddiqui, T., Sariya, S., Reyes‐Dumeyer, D., Flowers, X. E., Cardoso, S. A. L., Jager, P. L. D., Bennett, D. A., et al. (2022) · Acta Neuropathologica · doi:10.1007/s00401-022-02431-6 · Cited by 47 · see citing works
Self-citationLogsdon, B. A., Perumal, T. M., Swarup, V., Wang, M., Funk, C. C., Gaiteri, C., Allen, M., Wang, X. B., Dammer, E. B., Srivastava, G. P., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/510420 · Cited by 46 · see citing works
The role of biomarkers and imaging in the clinical diagnosis of dementia
Bayer, A. J. (2018) · Age and Ageing · doi:10.1093/ageing/afy004 · Cited by 45 · see citing works
Concordance of Clinical Alzheimer Diagnosis and Neuropathological Features at Autopsy
Gauthreaux, K., Bonnett, T. A., Besser, L. M., Brenowitz, W. D., Teylan, M., Mock, C., Chen, Y.-C., Chan, K. C. G., Keene, C. D., Zhou, X.-H., et al. (2020) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlaa014 · Cited by 44 · see citing works
Self-citationA population‐based meta‐analysis of circulating GFAP for cognition and dementia risk
Gonzales, M. M., Wiedner, C. D., Wang, C.-P., Liu, Q.-Q., Bis, J. C., Li, Z.-G., Himali, J., Ghosh, S., Thomas, E. A., Parent, D. M., et al. (2022) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.51652 · Cited by 37 · see citing works
Beach, T. G., Adler, C. H., Zhang, N., Serrano, G. E., Sue, L. I., Driver‐Dunckley, E. D., Mehta, S. H., Zamrini, E., Sabbagh, M. N., Shill, H. A., et al. (2020) · PLoS ONE · doi:10.1371/journal.pone.0231720 · Cited by 43 · see citing works
REM Sleep Behavior Disorder and Alzheimer’s Disease: Definitely No Relationship?
Galbiati, A., Carli, G., Hensley, M., & Ferini‐Strambi, L. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-171164 · Cited by 42 · see citing works
Sensory Loss and Risk of Dementia
Lad, M., Sedley, W., & Griffiths, T. D. (2022) · The Neuroscientist · doi:10.1177/10738584221126090 · Cited by 41 · see citing works
Gauthier, S. G., Zhang, H., Ng, K. P., Pascoal, T. A., & Rosa‐Neto, P. (2018) · Translational Neurodegeneration · doi:10.1186/s40035-018-0117-9 · Cited by 40 · see citing works
MR approaches in neurodegenerative disorders
Blamire, A. M. (2018) · Progress in Nuclear Magnetic Resonance Spectroscopy · doi:10.1016/j.pnmrs.2018.11.001 · Cited by 37 · see citing works
Dementia-related psychosis and the potential role for pimavanserin
Cummings, J. L., Devanand, D. P., & Stahl, S. M. (2020) · CNS Spectrums · doi:10.1017/s1092852920001765 · Cited by 35 · see citing works
Brain cell somatic gene recombination and its phylogenetic foundations
Kaeser, G. E., & Chun, J. J. M. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.rev120.009192 · Cited by 32 · see citing works
Gray to white matter signal ratio as a novel biomarker of neurodegeneration in Alzheimer’s disease
Putcha, D., Katsumi, Y., Brickhouse, M. J., Flaherty, R., Salat, D. H., Touroutoglou, A., & Dickerson, B. C. (2022) · NeuroImage Clinical · doi:10.1016/j.nicl.2022.103303 · Cited by 28 · see citing works
Distinct White Matter Changes Associated with Cerebrospinal Fluid Amyloid-β 1-42 and Hypertension
Al‐Janabi, O. M., Brown, C. A., Bahrani, A. A., Abner, E. L., Barber, J. M., Gold, B. T., Goldstein, L. B., Murphy, R. R., Nelson, P. T., Johnson, N. F., et al. (2018) · Journal of Alzheimer s Disease · doi:10.3233/jad-180663 · Cited by 26 · see citing works
Gu, Y., Kociolek, A. J., Fernández, K. K., Cosentino, S., Zhu, C. W., Jin, Z., Leverenz, J. B., & Stern, Y. (2022) · Neurology · doi:10.1212/wnl.0000000000200259 · Cited by 24 · see citing works
Wurm, R., Klotz, S., Rahimi, J., Katzenschlager, R., Lindeck‐Pozza, E., Regelsberger, G., Danics, K., Kapás, I., Bíró, Z., Stögmann, E., et al. (2020) · European Journal of Neurology · doi:10.1111/ene.14321 · Cited by 24 · see citing works
Multiple biomarkers improve diagnostic accuracy across Lewy body and Alzheimer's disease spectra
Plastini, M. J., Ruiz, C. A., Young, C. B., Wilson, E. N., Shahid, M., Lamoureux, J., Andreasson, K. I., Kerchner, G. A., Montine, T. J., Henderson, V. W., et al. (2024) · Annals of Clinical and Translational Neurology · doi:10.1002/acn3.52034 · Cited by 23 · see citing works
Clinical characteristics of Lewy body dementia in Chinese memory clinics
China Lewy Body Disease Collaborative Alliance, Gan, J., Liu, S., Wang, X., Shi, Z., Shen, L., Li, X., Guo, Q., Yuan, J., Zhang, N., et al. (2021) · BMC Neurology · doi:10.1186/s12883-021-02169-w · Cited by 22 · see citing works
Mosaic Somatic Gene Recombination as a Potentially Unifying Hypothesis for Alzheimer’s Disease
Kaeser, G. E., & Chun, J. J. M. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00390 · Cited by 22 · see citing works
Advances in the genetics and pathology of Lewy body dementia
Scholz, S. W., Okubadejo, N. U., Prakash, P., Liddelow, S. A., Ryten, M., & Halliday, G. M. (2025) · The Lancet Neurology · doi:10.1016/s1474-4422(25)00363-1 · Cited by 18 · see citing works
The molecular spectrum of amyloid‐beta (Aβ) in neurodegenerative diseases beyond Alzheimer's disease
Ichimata, S., Yoshida, K., Li, J., Rogaeva, E. A., Lang, A. E., & Kovács, G. G. (2023) · Brain Pathology · doi:10.1111/bpa.13210 · Cited by 17 · see citing works
Kurasz, A. M., Wit, L. D., Smith, G. E., & Armstrong, M. J. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-220297 · Cited by 15 · see citing works
Utility of spontaneous animal models of Alzheimer’s disease in preclinical efficacy studies
Zeiss, C. J. (2020) · Cell and Tissue Research · doi:10.1007/s00441-020-03198-6 · Cited by 14 · see citing works
Neuropathologic Changes of Alzheimer’s Disease and Related Dementias: Relevance to Future Prevention
White, L. R., Corrada, M. M., Kawas, C. H., Cholerton, B., Edland, S. E., Flanagan, M. E., & Montine, T. J. (2023) · Journal of Alzheimer s Disease · doi:10.3233/jad-230331 · Cited by 13 · see citing works
Graves, L. V., Holden, H. M., Etten, E. J. V., Delano‐Wood, L., Bondi, M. W., Salmon, D. P., Corey‐Bloom, J., Gilbert, P. E., & Delis, D. C. (2019) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617719000407 · Cited by 11 · see citing works
Petersen, J. D., Siersma, V., Christensen, R. D., Storsveen, M. M., Nielsen, C. T., Vass, M., & Waldorff, F. B. (2018) · Scandinavian Journal of Public Health · doi:10.1177/1403494818782094 · Cited by 10 · see citing works
Burgio, M. I., Veronese, N., Sarà, D., Saccaro, C., Masnata, R., Vassallo, G., Catania, A., Catanese, G., Mueller, C., Smith, L., et al. (2024) · Aging Clinical and Experimental Research · doi:10.1007/s40520-024-02704-y · Cited by 8 · see citing works
RNA Isoform Diversity in Human Neurodegenerative Diseases
Liu, C. S., Park, C. Y., Ngo, T., Saikumar, J., Palmer, C. R., Shahnaee, A., Romanow, W. J., & Chun, J. J. M. (2024) · eNeuro · doi:10.1523/eneuro.0296-24.2024 · Cited by 8 · see citing works
Liu, L., Zhang, C. S., Zhang, A. L., Cai, Y., & Xue, C. C. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1341074 · Cited by 7 · see citing works
Hunter, S., Walsh, S., & Brayne, C. (2025) · Molecular Psychiatry · doi:10.1038/s41380-025-03156-0 · Cited by 6 · see citing works
Lee, Y., Kang, S. W., Lee, S., Jeon, S., Ye, B. S., Yun, M., & Initiative, T. A. D. N. (2025) · Journal of Clinical Neurology · doi:10.3988/jcn.2025.0218 · Cited by 6 · see citing works
Travaglini, K. J., Gabitto, M. I., Ding, Y., Agrawal, A., Postupna, N. O., Mahoney, J. T., Kaplan, E. S., Melief, E. J., Goldy, J., Chakka, A. B., et al. (2026) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2026.07.01.734821 · Cited by 7 · see citing works
Self-citationIoannou, K., Perrin, R. J., Abdullaieva, K., Blūma, M., Leuzy, A., Poulakis, K., Religa, D., Rodriguez‐Vieitez, E., Chiotis, K., & Initiative, A. D. N. (2025) · Acta Neuropathologica · doi:10.1007/s00401-025-02960-w · Cited by 5 · see citing works
Lelos, M. J. (2020) · Elsevier eBooks · doi:10.1016/b978-0-12-818084-6.00002-7 · Cited by 5 · see citing works
Neuropsychological and clinical indicators of Lewy body and Alzheimer's pathology
Simpson, A., Wyman‐Chick, K. A., & Daniel, M. S. (2025) · Journal of Alzheimer s Disease Reports · doi:10.1177/25424823241304386 · Cited by 4 · see citing works
Symptoms and Diagnosis of Dementia
Sharifi, F., Ghandali, R., Alimohammadi, M., & Ahmadipour, P. (2024) · Nutritional neurosciences · doi:10.1007/978-981-97-4117-5_3 · Cited by 3 · see citing works
Effect Modifiers of the Association of Blood Pressure With Brain Amyloid and Tau Pathology
Cai, W., Neitzel, J., Glodzik, L., Blacker, D., & Ma, Y. (2025) · Neurology · doi:10.1212/wnl.0000000000213441 · Cited by 3 · see citing works
Brandt, T. A., Frangiosa, T., Biggar, V. S., Taylor, A., Valentine, J. E., Keller, B., Price, M. A., DeMuro, C., & Abler, V. (2021) · Clinical Gerontologist · doi:10.1080/07317115.2021.1957050 · Cited by 3 · see citing works
Degenerative or Debilitative Neurologic Syndromes
Parish, A. L. (2018) · Nursing Clinics of North America · doi:10.1016/j.cnur.2018.05.002 · Cited by 3 · see citing works
Neuropathology and Biomarker Correlates of Late Onset Alzheimer’s Disease in Aged Old World Monkeys
Zeiss, C. J., Duque, A., & Huttner, A. J. (2025) · Toxicologic Pathology · doi:10.1177/01926233251388069 · Cited by 2 · see citing works
Spontaneous isomerization of tau is most prevalent in Alzheimer’s disease
Hubbard, E. E., Reagle, K., Lui, M. K., Derbez-Morin, M., Merrihew, G. E., MacCoss, M. J., & Julian, R. R. (2026) · NeuroMarkers. · doi:10.1016/j.neumar.2025.100152 · Cited by 2 · see citing works
Mursyid, F., Hasan, A., Owkwulu, T., Wilson, M., Huang, Y.-F., & Sastranagara, H. (2023) · Sriwijaya Journal of Neurology · doi:10.59345/sjn.v1i2.81 · Cited by 2 · see citing works
The Association of Ancillary Diagnostic Tests With Outcome in Dementia
Lindhout, J. E., Richard, E., Hafdi, M., Perry, M., van Charante, E. P. M., & van Gool, W. A. (2024) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2024.105040 · Cited by 2 · see citing works
To Drive or Not to Drive: When There Is Dementia
Selway, J. S. (2018) · The Journal for Nurse Practitioners · doi:10.1016/j.nurpra.2017.12.033 · Cited by 2 · see citing works
FMNL2 interacts with cerebrovascular risk factors to alter Alzheimer’s disease riskPreprint
Raghavan, N. S., Sariya, S., Lee, A., Gao, Y., Reyes‐Dumeyer, D., Jager, P. L. D., Bennett, D. A., Menon, V., Lantigua, R., Kukull, W. A., et al. (2020) · medRxiv · doi:10.1101/2020.08.30.20184879 · Cited by 2 · see citing works
Self-citationThe Brain Aging National Cohort-PUMC: study design and baseline characteristics
Han, F., Qiu, W., Zhou, L., Ni, J., Yao, M., Liu, Y., Hou, B., Cui, R., Feng, F., Li, F., et al. (2023) · Human Brain · doi:10.37819/hb.2.333 · Cited by 1 · see citing works
Oomens, J. E., Biber, S., Albert, M., Alosco, M. L., Arfanakis, K., Benzinger, T. L. S., Brewer, J. B., Burns, J. M., Chin, E. M., Chin, N. A., et al. (2025) · Alzheimer s & Dementia · doi:10.1002/alz.70880 · Cited by 1 · see citing works
Self-citationRoss, D., Split, M., Kunicki, Z. J., Keszycki, R. M., Prieto, S., Vito, A. N. D., Manoochehri, M., Huey, E. D., & Barker, M. S. (2026) · Neurology · doi:10.1212/wnl.0000000000214750 · Cited by 1 · see citing works
Calderón‐Garcidueñas, L., Nalbantoğlu, Ö. U., González-Maciel, A., & Torres‐Jardón, R. (2026) · Journal of Neuropathology & Experimental Neurology · doi:10.1093/jnen/nlag028 · Cited by 1 · see citing works
Cardiorespiratory Fitness, Coronary Artery Calcium, and Risk of Later-Life Dementia
Gerber, Y., Leonard, D., Shuval, K., Barlow, C. E., Meernik, C., Pavlovic, A., Li, Q., Appiah, D., Gabriel, K. P., Radford, N. B., et al. (2026) · JACC Advances · doi:10.1016/j.jacadv.2026.103079 · Cited by 1 · see citing works
Lewy Body Disease Across Aging: Clinical and Neuropathological Correlates in a Population Brain Bank
Paes, V. R., Pereira, F. L., Silva, C. M., de Moraes, F. O. C., Padrão, I. L., Justo, A. F. O., Rodriguez, R. D., Naslavsky, M. S., Leite, R. E. P., Pasqualucci, C. A., et al. (2026) · Movement Disorders · doi:10.1002/mds.70515 · Cited by 1 · see citing works
Relapse in Dementia-related Psychosis and Clinical Decisions
Soto-Martin, M., Foff, E. P., & Devanand, D. P. (2022) · Alzheimer Disease & Associated Disorders · doi:10.1097/wad.0000000000000480 · Cited by 1 · see citing works
Sakakibara, R., Tateno, F., Aiba, Y., Ogata, T., Kishi, M., Terada, H., Inaoka, T., Nakatsuka, T., Katsuragawa, S., & Kato, Y. (2019) · Neurology and Clinical Neuroscience · doi:10.1111/ncn3.12297 · Cited by 1 · see citing works
Heterogeneity in Alzheimer’s/Vascular Spectrum Dementia
Emrani, S., Lamar, M., Price, C. C., Wasserman, V., Matusz, E. F., Swenson, R. A., Heilman, K. M., & Libon, D. J. (2020) · Oxford University Press eBooks · doi:10.1093/oso/9780190634230.003.0003 · Cited by 1 · see citing works
Avan, A., Amiri, A., Mokhber, N., Erfanian, M., Cipriano, L. E., Stranges, S., Shojaeianbabaei, G., Abootalebi, S., & Azarpazhooh, M. R. (2021) · Journal of Clinical Neuroscience · doi:10.1016/j.jocn.2021.05.044 · Cited by 1 · see citing works
Brain pathological changes from population-based studies
Cao, Y., Huang, M., Shu, M.-J., & Zhu, Y. (2022) · Human Brain · doi:10.37819/hb.001.001.0205 · Cited by 1 · see citing works
Henderson, V. W., & Kerchner, G. A. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-801238-3.00017-9
Chen, A., Daffner, K. R., & Gale, S. A. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-12642-0.00015-3
Zhang, T., Xu, Q., & Zhou, J. (2025) · European journal of medical research · doi:10.1186/s40001-025-03638-5
Étude de la propagation prion-like de l'alpha-synucléine dans des réseaux de neurones reconstruits
Courte, J. (2019) · theses.fr (ABES) · doi:10.70675/95ccfbd6zedb2z4a1bz8024zb46a3ec60ebf
Glial cells in neurodegenerative diseases: a review
Pranto, A. H., Khandker, S. S., Uddin, M. E., Aktar, S., Mumu, S. I., Khan, R. I., Chowdhury, N. K., Prekbunjun, J., Zisan, A., & Begum, R. (2025) · Neurophysiology · doi:10.1007/s11062-026-10018-0
Cognitive functioning and dementia in aging women
Mielke, M. M., Lee, J., & Yaffe, K. S. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-45863-7.00109-8
Rumpf, S.-L., Struebing, F. L., Nalbach, K., Vargiu, C. M., Berg, G., Lichtenthaler, S. F., Parchi, P., Gao, P., Weilin, C. H. E. N., Brendel, M., et al. (2026) · Nature Communications · doi:10.1038/s41467-026-74961-6
Sánchez-Jiménez, F. J., Cantón-Habas, V., Reyes-Medina, M. J., & Carrera-González, M. P. (2026) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2026.1909175
- Authors
- Brenowitz, W. D., Keene, C. D., Hawes, S. E., Hubbard, R. A., Longstreth, W. T., Woltjer, R. L., Crane, P. K., Larson, E. B., & Kukull, W. A.
- Affiliations
- University of Washington (US)
- University of Pennsylvania (US)
- Oregon Health & Science University (US)
- Kaiser Permanente Washington Health Research Institute (US)
- Corresponding author
- Brenowitz, Willa D.
- ORCID
- Venue
- Neurobiology of Aging
- Publisher
- Elsevier BV
- Published
- 2017-05
- Volume
- 53
- Pages
- 83-92
- ISSN
- 0197-4580 (ISSN-L)
- PMC
- PMC5385292
- OpenAlex
- W2580671663
- Cited by
- 88
- References
- 63
- Citations by year
- 2026: 8 · 2025: 12 · 2024: 9 · 2023: 5 · 2022: 10 · 2021: 6 · 2020: 13 · 2019: 10 · 2018: 12 · 2017: 1 · 2014: 1
- FWCI
- 8.09
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Neurobiology of Aging (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- Oregon Health and Science University
- National Institute on Aging (P30AG010129, P30AG010133, R01AG024059, P30AG028383, P30AG012300, P50AG005133, U01AG006781, U01AG016976, P50AG005131, P50AG005138, P50AG016570, P30AG010124, P50AG016573, P50AG047366, P30AG008017, P30AG010161, P30AG008051, P50AG008702, P50AG033514, P30AG035982, P50AG005681, P50AG005142, P50AG047270, P30AG019610, P50AG005146, P30AG013846, P50AG005136, P50AG005134, P30AG013854, P50AG025688, P50AG047266, P50AG023501, P50AG016574)
- National Center for Research Resources (M01RR000334, UL1RR024140)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Dementia and Cognitive Impairment Research
- Health Sciences › Medicine › Physiology › Alzheimer's disease research and treatments
- Health Sciences › Medicine › Neurology › Parkinson's Disease Mechanisms and Treatments
- Keywords
- Lewy body disease, vascular brain injury, dementia etiology, cortical Lewy bodies, Adult Changes in Thought study, autopsy specimens, dementia diagnosis
- MeSH terms
- Aged, Aged, 80 and over, Aging, Alzheimer Disease, Autopsy, Brain, Female, Humans, Male, Comorbidity, Cerebrovascular Trauma, Lewy Body Disease
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Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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