Cited by 204Functional Brain Connectivity StudiesHemispheric Asymmetry in NeuroscienceMemory and Neural Mechanisms

The DOI matches its Crossref record; 66 of the 67 references it cites were found in a registry or an index.

Sex-related differences in amygdala functional connectivity during resting conditions

Kilpatrick, L.A., Zald, D.H., Pardo, J.V., Cahill, L.F.·2006·NeuroImage

DOI 10.1016/j.neuroimage.2005.09.065

Open this paper in CoChat — free account

Abstract

Recent neuroimaging studies have established a sex-related hemispheric lateralization of amygdala involvement in memory for emotionally arousing material. Here, we examine the possibility that sex-related differences in amygdala involvement in memory for emotional material develop from differential patterns of amygdala functional connectivity evident in the resting brain. Seed voxel partial least square analyses of regional cerebral blood flow data revealed significant sex-related differences in amygdala functional connectivity during resting conditions. The right amygdala was associated with greater functional connectivity in men than in women. In contrast, the left amygdala was associated with greater functional connectivity in women than in men. Furthermore, the regions displaying stronger functional connectivity with the right amygdala in males (sensorimotor cortex, striatum, pulvinar) differed from those displaying stronger functional connectivity with the left amygdala in females (subgenual cortex, hypothalamus). These differences in functional connectivity at rest may link to sex-related differences in medical and psychiatric disorders.

Integrity signals

Registry

Crossref · 10.1016/j.neuroimage.2005.09.065

Cites

66 of 66 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Memory - A century of consolidation
McGaugh, J. L. (2000) · Science · doi:10.1126/science.287.5451.248 · Cited by 4,250
Biobehavioral responses to stress in females: Tend-and-befriend, not fight-or-flight.
Taylor, S. E., Klein, L. C., Lewis, B. P., Gruenewald, T. L., Gurung, R. A. R., & Updegraff, J. A. (2000) · Psychological Review · doi:10.1037/0033-295x.107.3.411 · Cited by 3,308
The amygdala: Neurobiological aspects of emotion, memory, and mental dysfunction.
Aggleton, J. P. (1992) · Wiley-Liss eBooks · Cited by 1,536
The amygdala: Neurobiological aspects of emotion, memory and mental dysfunction
Scheel-Krüger, J. (1993) · Journal of Chemical Neuroanatomy · doi:10.1016/0891-0618(93)90037-5 · Cited by 1,281
Limbic connections of the orbital and medial prefrontal cortex in macaque monkeys
Carmichael, S. T., & Price, J. L. (1995) · Journal of Comparative Neurology · doi:10.1002/cne.903630408 · Cited by 1,197
Sex differences in pain
Berkley, K. J. (1997) · Behavioral and Brain Sciences · doi:10.1017/s0140525x97221485 · Cited by 1,125
Spatial attention and neglect: parietal, frontal and cingulate contributions to the mental representation and attentional targeting of salient extrapersonal events
Mesulam, M.-M. (1999) · Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rstb.1999.0482 · Cited by 1,096
Spatial Pattern Analysis of Functional Brain Images Using Partial Least Squares
McIntosh, A. R., Bookstein, F. L., Haxby, J. V., & Grady, C. L. (1996) · NeuroImage · doi:10.1006/nimg.1996.0016 · Cited by 1,095
Partial least squares analysis of neuroimaging data: applications and advances
McIntosh, A. R., & Lobaugh, N. J. (2004) · NeuroImage · doi:10.1016/j.neuroimage.2004.07.020 · Cited by 1,084
Normal Sexual Dimorphism of the Adult Human Brain Assessed by In Vivo Magnetic Resonance Imaging
Goldstein, J. M. (2001) · Cerebral Cortex · doi:10.1093/cercor/11.6.490 · Cited by 1,052
The Amygdala: a functional analysis
Aggleton, J. P. (2000) · Cited by 966
Amygdala activity related to enhanced memory for pleasant and aversive stimuli
Hamann, S. B., Ely, T. D., Grafton, S. T., & Kilts, C. D. (1999) · Nature Neuroscience · doi:10.1038/6404 · Cited by 941
Amygdala activity at encoding correlated with long-term, free recall of emotional information.
Cahill, L. F., Haier, R. J., Fallon, J., Alkire, M. T., Tang, C. Y., Keator, D., Wu, J. C., & McGaugh, J. L. (1996) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.93.15.8016 · Cited by 928
Self-citation
Analytic 3D image reconstruction using all detected events
Kinahan, P. E., & Rogers, J. G. (1989) · IEEE Transactions on Nuclear Science · doi:10.1109/23.34585 · Cited by 769
Event-Related Activation in the Human Amygdala Associates with Later Memory for Individual Emotional Experience
Canli, T., Zhao, Z., Brewer, J., Gabrieli, J. D. E., & Cahill, L. (2000) · The Journal of Neuroscience · doi:10.1523/jneurosci.20-19-j0004.2000 · Cited by 697
Self-citation
Sex differences in the neural basis of emotional memories
Canli, T., Desmond, J. E., Zhao, Z., & Gabrieli, J. D. E. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.162356599 · Cited by 664
Sex Differences in Human Brain Morphometry and Metabolism: An In Vivo Quantitative Magnetic Resonance Imaging and Positron Emission Tomography Study on the Effect of Aging
Murphy, D. (1996) · Archives of General Psychiatry · doi:10.1001/archpsyc.1996.01830070031007 · Cited by 527
Handbook of the hypothalamus
Morgane, P. J., & Panksepp, J. (1979) · M. Dekker eBooks · Cited by 500
Towards a network theory of cognition
McIntosh, A. R. (2000) · Neural Networks · doi:10.1016/s0893-6080(00)00059-9 · Cited by 500
The subcortical anatomy of human spatial neglect: putamen, caudate nucleus and pulvinar
Karnath, H., Himmelbach, M., & Rorden, C. (2002) · Brain · doi:10.1093/brain/awf032 · Cited by 476
Sex-related difference in amygdala activity during emotionally influenced memory storage
Cahill, L., Haier, R. J., White, N. S., Fallon, J., Kilpatrick, L., Lawrence, C., Potkin, S. G., & Alkire, M. T. (2001) · Neurobiology of Learning and Memory · doi:10.1006/nlme.2000.3999 · Cited by 413
Anatomic standardization: linear scaling and nonlinear warping of functional brain images.
Minoshima, S., Koeppe, R. A., Frey, K. A., & Kuhl, D. E. (1994) · PubMed · Cited by 404
Gender, sex hormones and autonomic nervous control of the cardiovascular system
Dart, A. M. (2002) · Cardiovascular Research · doi:10.1016/s0008-6363(01)00508-9 · Cited by 382
Volumetric reduction in left subgenual prefrontal cortex in early onset depression
Botteron, K. N., Raichle, M. E., Drevets, W. C., Heath, A. C., & Todd, R. D. (2002) · Biological Psychiatry · doi:10.1016/s0006-3223(01)01280-x · Cited by 371
Sex-Related Hemispheric Lateralization of Amygdala Function in Emotionally Influenced Memory: An fMRI InvestigationPreprint
Cahill, L. F., Uncapher, M. R., Kilpatrick, L. A., Alkire, M. T., & Turner, J. A. (2004) · Learning & Memory · doi:10.1101/lm.70504 · Cited by 362
Self-citation
Sex differences in subregions of the medial nucleus of the amygdala and the bed nucleus of the stria terminalis of the rat
Hines, M., Allen, L. S., & Gorski, R. A. (1992) · Brain Research · doi:10.1016/0006-8993(92)90068-k · Cited by 347
Sex Differences in Regional Cerebral Glucose Metabolism During a Resting State
Gur, R. C., Mozley, L. H., Mozley, P. D., Resnick, S. M., Karp, J. S., Alavi, A. A., Arnold, S. E., & Gur, R. E. (1995) · Science · doi:10.1126/science.7824953 · Cited by 340
Gender and Age Influences on Human Brain Mu-Opioid Receptor Binding Measured by PET
Zubieta, J., Dannals, R. F., & Frost, J. J. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.6.842 · Cited by 335
White Matter Asymmetry in the Human Brain: A Diffusion Tensor MRI Study
Büchel, C., Raedler, T. J., Sommer, M., Sach, M., Weiller, C., & Koch, M. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh055 · Cited by 335
Sex-related Differences in a Gambling Task and Its Neurological Correlates
Bolla, K. I. (2004) · Cerebral Cortex · doi:10.1093/cercor/bhh083 · Cited by 333
Topographic organization of medial pulvinar connections with the prefrontal cortex in the rhesus monkey
Romanski, L. M., Giguere, M., Bates, J. F., & Goldman-Rakic, P. S. (1997) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19970317)379:3 · Cited by 323
Subgenual Cingulate Cortex Volume in First-Episode Psychosis
Hirayasu, Y., Shenton, M. E., Salisbury, D. F., Kwon, J. S., Wible, C. G., Fischer, I. A., Yurgelun-Todd, D., Zarate, C., Kikinis, R., Jolesz, F. A., et al. (1999) · American Journal of Psychiatry · doi:10.1176/ajp.156.7.1091 · Cited by 301
Amygdala modulation of parahippocampal and frontal regions during emotionally influenced memory storage
Kilpatrick, L. A. (2003) · NeuroImage · doi:10.1016/j.neuroimage.2003.08.006 · Cited by 294
Self-citation
Sex-related differences in IBS patients: central processing of visceral stimuli
Naliboff, B. D., Berman, S. M., Chang, L., Derbyshire, S. W. G., Suyenobu, B. Y., Vogt, B. A., Mandelkern, M. A., & Mayer, E. A. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)00400-1 · Cited by 291
Amygdaloid CRF Pathways: Role in Autonomic, Neuroendocrine, and Behavioral Responses to Stress
Gray, T. S. (1993) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1993.tb49922.x · Cited by 288
Neurobehavioral effects of prenatal alcohol: Part II. Partial Least Squares analysis
Sampson, P. D., Streissguth, A. P., Barr, H. M., & Bookstein, F. L. (1989) · Neurotoxicology and Teratology · doi:10.1016/0892-0362(89)90025-1 · Cited by 280
An fMRI study investigating cognitive modulation of brain regions associated with emotional processing of visual stimuli
Keightley, M., Winocur, G., Graham, S. J., Mayberg, H. S., Hevenor, S. J., & Grady, C. L. (2003) · Neuropsychologia · doi:10.1016/s0028-3932(02)00199-9 · Cited by 222
Gender differences in regional cerebral blood flow during transient self-induced sadness or happiness
George, M. S., Ketter, T. A., Parekh, P. I., Herscovitch, P., & Post, R. M. (1996) · Biological Psychiatry · doi:10.1016/0006-3223(95)00572-2 · Cited by 222
Sexual dimorphism in synaptic organization in the amygdala and its dependence on neonatal hormone environment
Nishizuka, M., & Arai, Y. (1981) · Brain Research · doi:10.1016/0006-8993(81)90029-9 · Cited by 193
Brain activity in ventromedial prefrontal cortex correlates with individual differences in negative affect
Zald, D. H., Mattson, D. L., & Pardo, J. V. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.042457199 · Cited by 186
Self-citation
Cerebral glucose metabolic rates in normal human females versus normal males
Baxter, L. R., Mazziotta, J. C., Phelps, M. E., Selin, C. E., Guzé, B. H., & Fairbanks, L. A. (1987) · Psychiatry Research · doi:10.1016/0165-1781(87)90028-x · Cited by 166
The influence of handedness and gender on the microstructure of the human corpus callosum: a diffusion-tensor magnetic resonance imaging study
Westerhausen, R., Walter, C., Kreuder, F., Wittling, R. A., Schweiger, E., & Wittling, W. (2003) · Neuroscience Letters · doi:10.1016/j.neulet.2003.07.011 · Cited by 146
Neurochemical and connectional organization of the dorsal pulvinar complex in monkeys
Gutiérrez, C., Cola, M. G., Seltzer, B., & Cusick, C. G. (2000) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(20000327)419:1 · Cited by 142
Gender-related differences in regional cerebral glucose metabolism in normal volunteers
Andreason, P., Zametkin, A. J., Guo, A. C., Baldwin, P., & Cohen, R. M. (1994) · Psychiatry Research · doi:10.1016/0165-1781(94)90037-x · Cited by 140
The medial frontal cortex and gastric motility: Microstimulation results and their possible significance for the overall pattern of organization of rat frontal and parietal cortex
Hurley-Gius, K. M., & Neafsey, E. J. (1986) · Brain Research · doi:10.1016/0006-8993(86)91635-5 · Cited by 138
Correlation between Human Personality and Neural Activity in Cerebral Cortex
Sugiura, M., Kawashima, R., Nakagawa, M., Okada, K., Sato, T., Goto, R., Sato, K., Ono, S., Schormann, T., Zilles, K., et al. (2000) · NeuroImage · doi:10.1006/nimg.2000.0564 · Cited by 129
GABA neurons provide a rich input to microvessels but not nitric oxide neurons in the rat cerebral cortex: A means for direct regulation of local cerebral blood flow
Vaucher, E., Tong, X., Cholet, N., Lantin, S., & Hamel, É. (2000) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(20000529)421:2 · Cited by 126
Sex differences in brain-behavior relationships between verbal episodic memory and resting regional cerebral blood flow
Ragland, J. D., Coleman, A. R., Gur, R. C., Glahn, D. C., & Gur, R. E. (2000) · Neuropsychologia · doi:10.1016/s0028-3932(99)00086-x · Cited by 120
Sex differences in frontal lobe white matter microstructure: a DTI study
Szeszko, P. R., Vogel, J., Ashtari, M., Malhotra, A. K., Bates, J., Kane, J. M., Bilder, R. M., Frevert, T. A., & Lim, K. O. (2003) · Neuroreport · doi:10.1097/00001756-200312190-00035 · Cited by 96
Reduced glucose metabolism in the subgenual prefrontal cortex in unipolar depression
Drevets, W. C., Öngür, D., & Price, J. (1998) · Molecular Psychiatry · doi:10.1038/sj.mp.4000380 · Cited by 92
Gender differences in cerebral glucose metabolism: a PET study
Kawachi, T., Ishii, K., Sakamoto, S., Matsui, M., Mori, T., & Sasaki, M. (2002) · Journal of the Neurological Sciences · doi:10.1016/s0022-510x(02)00112-0 · Cited by 83
Determinants of resting regional cerebral blood flow in normal subjects
Mathew, R. J., Wilson, W. H., & Tant, S. R. (1986) · Biological Psychiatry · doi:10.1016/0006-3223(86)90264-7 · Cited by 71
THE MOMENTS OF THE z AND F DISTRIBUTIONS
David, F. N. (1949) · Biometrika · doi:10.1093/biomet/36.3-4.394 · Cited by 67
Intersubject Variability and Reproducibility of 15O PET Studies
Coles, J., Fryer, T. D., Bradley, P. G., Nortje, J., Smielewski, P. S., Rice, K. M., Clark, J. C., Pickard, J. D., & Menon, D. K. (2005) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600179 · Cited by 64
Handbook of the Hypothalamus
Gamble, H. J. (1982) · Europe PMC (PubMed Central) · Cited by 62
Gender differences in correlations of cerebral glucose matabolic rates in young normal adults
Azari, N. P., Рапопорт, С. И., Grady, C. L., DeCarli, C. S., Haxby, J. V., Schapiro, M. B., & Horwitz, B. (1992) · Brain Research · doi:10.1016/0006-8993(92)90817-s · Cited by 59
Effect of gender on glucose utilization rates in healthy humans: A positron emission tomography study
Miura, S., Schapiro, M. B., Grady, C. L., Kumar, A., Salerno, J. A., Kozachuk, W. E., Wagner, E., Рапопорт, С. И., & Horwitz, B. (1990) · Journal of Neuroscience Research · doi:10.1002/jnr.490270410 · Cited by 55
Simulating functional interactions in the brain: A model for examining correlations between regional cerebral metabolic rates
Horwitz, B. (1990) · International Journal of Bio-Medical Computing · doi:10.1016/0020-7101(90)90039-w · Cited by 52
Visualization and analysis of white matter structural asymmetry in diffusion tensor MRI data
Zhang, S., Bastin, M. E., Laidlaw, D. H., Sinha, S. K., Armitage, P. A., & Deisboeck, T. S. (2003) · Magnetic Resonance in Medicine · doi:10.1002/mrm.10673 · Cited by 50
Sexual Dimorphism of the Bed Nucleus of the Stria Terminalis and the Amygdala
Stefanova, N., & Ovtscharoff, W. A. (2000) · Advances in anatomy, embryology and cell biology · doi:10.1007/978-3-642-57269-2 · Cited by 47
On the Marriage of Cognition and Neuroscience
McIntosh, A. R., Fitzpatrick, S. M., & Friston, K. J. (2001) · NeuroImage · doi:10.1006/nimg.2001.0941 · Cited by 31
Introduction
Stefanova, N., & Ovtscharoff, W. A. (2000) · Advances in anatomy, embryology and cell biology · doi:10.1007/978-3-642-57269-2_1 · Cited by 25
Effects on gastric secretion of frontal lobe stimulation.
Lm, D., Br, K., & Jf, F. (1949) · PubMed · Cited by 20
Zones of sexual dimorphism in the cortico-medial group of nuclei of the amygdaloid complex
Калимуллина, Л. Б. (1989) · Neuroscience and Behavioral Physiology · doi:10.1007/bf01148415 · Cited by 4
Untitled work
Xiong (1999) · doi:10.1002/(sici)1097-0193(1999)8:2/3
Prefrontal cortical projections to longitudinal columns in the midbrain periaqueductal gray in Macaque monkeys
An, X., Bandler, R., �ng�r, D., & Price, J. L. (1998) · The Journal of Comparative Neurology · doi:10.1002/(sici)1096-9861(19981130)401:4

Flagged first, then by citations

1 of the 67 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

Cahill, 2001, Sex-related difference in amygdala activity during emotionally influenced memory storage, Neurobiol. Learn. Mem., 75, 1, 10.1006/nlme.2000.3999 · DOI · Paper page
Volkow, 1997, Gender differences in cerebeller metabolism: test–retest reproducibility, Am. J. Psychiatry, 54, 119

Sorted by citations

Why sex matters for neuroscience
Cahill, L. (2006) · Nature Reviews Neuroscience · doi:10.1038/nrn1909 · Cited by 1,540
Self-citation
Sex influences on the neurobiology of learning and memoryPreprint
Andreano, J. M., & Cahill, L. F. (2009) · Learning & Memory · doi:10.1101/lm.918309 · Cited by 714
Self-citation
Sex differences in brain activation to emotional stimuli: A meta-analysis of neuroimaging studies
Stevens, J. S., & Hamann, S. (2012) · Neuropsychologia · doi:10.1016/j.neuropsychologia.2012.03.011 · Cited by 588
Assessing functional connectivity in the human brain by fMRI
Rogers, B. P., Morgan, V. L., Newton, A. T., & Gore, J. C. (2007) · Magnetic Resonance Imaging · doi:10.1016/j.mri.2007.03.007 · Cited by 511
Anatomical insights into the interaction of emotion and cognition in the prefrontal cortex
Ray, R. D., & Zald, D. H. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2011.08.005 · Cited by 446
Self-citation

See all 204

Authors: Kilpatrick, L. A., Zald, D. H., Pardo, J. V., & Cahill, L. F.
Affiliations: University of California, Irvine (US)
Vanderbilt University (US)
Minneapolis VA Health Care System (US)
Corresponding author: Kilpatrick, L.A.
ORCID: Kilpatrick, L.A.
Zald, D.H.
Pardo, J.V.
Venue: NeuroImage
Publisher: Elsevier BV
Published: 2006-04
Volume: 30
Issue: 2
Pages: 452-461
ISSN: 1053-8119 (ISSN-L)
DOI: 10.1016/j.neuroimage.2005.09.065
OpenAlex: W1971276070
Cited by: 204
References: 67
Citations by year: 2026: 2 · 2025: 4 · 2024: 6 · 2023: 6 · 2022: 8 · 2021: 6 · 2020: 13 · 2019: 7 · 2018: 15 · 2017: 15 · 2016: 14 · 2015: 16 · 2014: 12 · 2013: 14 · 2012: 10
FWCI: 4.12
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: NeuroImage (publishedVersion)
PubMed (publishedVersion)
Funders: U.S. Department of Veterans Affairs
National Institute of Mental Health (F32MH011641, MH 57508, MH11641)
Topics: Life Sciences › Neuroscience › Cognitive Neuroscience › Functional Brain Connectivity Studies
Life Sciences › Neuroscience › Cognitive Neuroscience › Hemispheric Asymmetry in Neuroscience
Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
Keywords: sex differences, amygdala, functional connectivity, resting state, hemispheric lateralization, emotional memory, regional cerebral blood flow, sensorimotor cortex, striatum, pulvinar, hypothalamus
MeSH terms: Adult, Amygdala, Brain, Cerebrovascular Circulation, Data Interpretation, Statistical, Emotions, Female, Humans, Image Processing, Computer-Assisted, Functional Laterality, Male, Nerve Net, Neural Pathways, Sex Characteristics, Least-Squares Analysis, Positron-Emission Tomography

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Sex-related differences in amygdala functional connectivity during resting conditions

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks