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A large scale multivariate parallel ICA method reveals novel imaging–genetic relationships for Alzheimer's disease in the ADNI cohort
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Genetic variations in VPS13 genes are emerging risk factors for sporadic, late-onset AD, with VPS13 variants exceeding even ApoE in risk contribution.
“Genetic variations in VPS13 genes are emerging risk factors for sporadic, late-onset AD, with VPS13 variants exceeding even ApoE in risk contribution [27].”
From Stabilizing the retromer complex rescues synaptic dysfunction and endosomal trafficking deficits in an Alzheimer’s disease mouse model (2025) · cites this paper as [27]
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Harold, D., Abraham, R., Hollingworth, P., Sims, R., Gerrish, A., Hamshere, M. L., Pahwa, J. S., Moskvina, V., Dowzell, K., Williams, A., et al. (2009) · Nature Genetics · doi:10.1038/ng.440 · Cited by 3,326
A method for making group inferences from functional MRI data using independent component analysis
Calhoun, V. D., Adali, T., Pearlson, G. D., & Pekar, J. J. (2001) · Human Brain Mapping · doi:10.1002/hbm.1048 · Cited by 2,994
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Self-citationReview Article: Genetics of Alzheimer Disease
Bekris, L. M., Yu, C.-E., Bird, T. D., & Tsuang, D. W. (2010) · Journal of Geriatric Psychiatry and Neurology · doi:10.1177/0891988710383571 · Cited by 1,029
Meta-analysis of Alzheimer’s disease risk with obesity, diabetes, and related disorders
Profenno, L. A., Porsteinsson, A. P., & Faraone, S. V. (2010) · Biological Psychiatry · doi:10.1016/j.biopsych.2009.02.013 · Cited by 718
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Potentially modifiable risk factors for dementia in identical twins
Gatz, M., Mortimer, J. A., Fratiglioni, L., Johansson, B., Berg, S., Reynolds, C. A., & Pedersen, N. L. (2006) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2006.01.002 · Cited by 239
Genetic Variation and Neuroimaging Measures in Alzheimer Disease
Biffi, A. (2010) · Archives of Neurology · doi:10.1001/archneurol.2010.108 · Cited by 222
Histological and Direct Evidence for the Role of Complement in the Neuroinflammation of AD
Veerhuis, R. (2011) · Current Alzheimer Research · doi:10.2174/156720511794604589 · Cited by 80
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Weiner, M. W., Veitch, D. P., Aisen, P. S., Beckett, L. A., Cairns, N. J., Cedarbaum, J., Green, R. C., Harvey, D., Jack, C. R., Jagust, W., et al. (2015) · Alzheimer's & Dementia · doi:10.1016/j.jalz.2014.11.001 · Cited by 348
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Metadata
- Authors
- Meda, S. A., Narayanan, B., Liu, J., Perrone-Bizzozero, N. I., Stevens, M. C., Calhoun, V. D., Glahn, D. C., Shen, L., Risacher, S. L., Saykin, A. J., & Pearlson, G. D.
- Venue
- NeuroImage
- Publisher
- Elsevier BV
- Published
- 2012-04
- Volume
- 60
- Issue
- 3
- Pages
- 1608-1621
- ISSN
- 1053-8119
- PMC
- PMC3312985
- Cited by
- 115
- References
- 9
- Language
- en
- Funders
- Eli Lilly and Company
- Siemens AG
- Welch Allyn Inc.
- NIH (R01 CA101318, R01 AG19771, RC2 AG036535, P30 AG10133–18S1, U01 AG032984, P30 AG010129, K01 AG030514, U01 AG024904)
- Indiana Economic Development Corporation (IEDC #87884)
- Foundation for the NIH (ROIEB005846)
- Alzheimer's Disease Neuroimaging Initiative (ADNI)
- National Institute on Aging
- National Institute of Biomedical Imaging and Bioengineering
- Abbott
- Alzheimer's Association
- Alzheimer's Drug Discovery Foundation
- Amorfix Life Sciences Ltd
- AstraZeneca
- Bayer HealthCare
- BioClinica, Inc
- Biogen Idec Inc
- Bristol-Myers Squibb Company
- Eisai Inc
- Elan Pharmaceuticals Inc
- F. Hoffmann-La Roche Ltd.
- Genentech, Inc.
- GE Healthcare
- Innogenetics, N.V
- Janssen Alzheimer Immunotherapy Research & Development, LLC
- Johnson & Johnson Pharmaceutical Research & Development LLC.
- Medpace, Inc
- Merck & Co., Inc
- Meso Scale Diagnostics, LLC
- Novartis Pharmaceuticals Corporation
- Pfizer Inc
- Servier
- Synarc Inc
- Takeda Pharmaceutical Company
- Canadian Institutes of Health Research
- Foundation for the National Institutes of Health
- Northern California Institute for Research and Education
- Dana Foundation
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