Increased App expression in a mouse model of Down’s syndrome disrupts NGF transport and causes cholinergic neuron degeneration

Cited by (113)

Items 101–113 of 113

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    Perez, Sylvia E., He, Bin, Muhammad, Nadeem, Oh, Kwang-Jin, Fahnestock, Margaret, Ikonomovic, Milos D., Mufson, Elliott J. · 2011 · Neurobiology of Disease
  6. Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr 682 -phosphorylated APP βCTF
    Im, Eunju, Jiang, Ying, Stavrides, Philip H., Darji, Sandipkumar, Erdjument-Bromage, Hediye, Neubert, Thomas A., Choi, Jun Yong, Wegiel, Jerzy, Lee, Ju-Hyun, Nixon, Ralph A. · 2023 · Science Advances
  7. Intracellular Aβ triggers neuron loss in the cholinergic system of the APP/PS1KI mouse model of Alzheimer's disease
    Christensen, Ditte Z., Bayer, Thomas A., Wirths, Oliver · 2010 · Neurobiology of Aging
  8. Amyloid precursor protein-induced axonopathies are independent of amyloid-β peptides
    Stokin, Gorazd B., Almenar-Queralt, Angels, Gunawardena, Shermali, Rodrigues, Elizabeth M., Falzone, Tomás, Kim, Jungsu, Lillo, Concepción, Mount, Stephanie L., Roberts, Elizabeth A., McGowan, Eileen et al. · 2008 · Human Molecular Genetics
  9. The human brain NGF metabolic pathway is impaired in the pre-clinical and clinical continuum of Alzheimers disease
    Pentz, Rowan, Iulita, M. Florencia, Ducatenzeiler, Adriana, Bennett, David A., Cuello, A. Claudio · 2021 · Molecular Psychiatry
  10. Presenilin controls kinesin-1 and dynein function during APP-vesicle transport in vivo
    Gunawardena, Shermali, Yang, Ge, Goldstein, Lawrence S.B. · 2013 · Human Molecular Genetics
  11. Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model
    Sawa, Mariko, Overk, Cassia, Becker, Ann, Derse, Dominique, Albay, Ricardo, Weldy, Kim, Salehi, Ahmad, Beach, Thomas G., Doran, Eric, Head, Elizabeth et al. · 2022 · Alzheimer's & Dementia
  12. Synaptic contact number and size in stratum radiatum CA1 of APP/PS1ΔE9 transgenic mice
    West, Mark J., Bach, Georg, Søderman, Andreas, Jensen, Jens Ledet · 2009 · Neurobiology of Aging
  13. Searching for new pharmacological targets for the treatment of Alzheimer's disease in Down syndrome
    Caraci, Filippo, Iulita, M. Florencia, Pentz, Rowan, Flores Aguilar, Lisi, Orciani, Chiara, Barone, Concetta, Romano, Corrado, Drago, Filippo, Cuello, A. Claudio · 2017 · European Journal of Pharmacology