The DOI matches its Crossref record; 72 of the 72 references it cites were found in a registry or an index.
Internally Generated Preactivation of Single Neurons in Human Medial Frontal Cortex Predicts Volition
Open accessAbstract
Understanding how self-initiated behavior is encoded by neuronal circuits in the human brain remains elusive. We recorded the activity of 1019 neurons while twelve subjects performed self-initiated finger movement. We report progressive neuronal recruitment over ~1500 ms before subjects report making the decision to move. We observed progressive increase or decrease in neuronal firing rate, particularly in the supplementary motor area (SMA), as the reported time of decision was approached. A population of 256 SMA neurons is sufficient to predict in single trials the impending decision to move with accuracy greater than 80% already 700 ms prior to subjects’ awareness. Furthermore, we predict, with a precision of a few hundred ms, the actual time point of this voluntary decision to move. We implement a computational model whereby volition emerges once a change in internally generated firing rate of neuronal assemblies crosses a threshold.
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Cites
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Self-citationThe Prefrontal Cortex—An Update
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Cited by
Neuronal Reward and Decision Signals: From Theories to Data
Schultz, W. (2015) · Physiological Reviews · doi:10.1152/physrev.00023.2014 · Cited by 1,126
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Empirical support for higher-order theories of conscious awareness
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Metadata
- Authors
- Fried, I., Mukamel, R., & Kreiman, G.
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2011-02
- Volume
- 69
- Issue
- 3
- Pages
- 548-562
- ISSN
- 0896-6273 (ISSN-L)
- OpenAlex
- W2136266574
- Cited by
- 478
- References
- 72
- FWCI
- 15.83
- Type
- journal article
- Language
- en
- Open access
- bronze
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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