The Pathobiology of Vascular Dementia

Iadecola, Costantino·2013·Neuron

Cites (364)

Items 201–341 of 341

  1. Blood brain barrier breakdown as the starting point of cerebral small vessel disease? - New insights from a rat model
    Schreiber, Stefanie, Bueche, Celine Zoe, Garz, Cornelia, Braun, Holger · 2013 · Experimental & Translational Stroke Medicine
  2. Vascular risk factors and Alzheimer's disease: are these risk factors for plaques and tangles or for concomitant vascular pathology that increases the likelihood of dementia? An evidence-based review
    Helena Chang Chui, Ling Zheng, Bruce Reed, Harry V. Vinters, Wendy Jean Mack · 2011 · Alzheimer s Research & Therapy
  3. Impaired endothelial function of the retinal vasculature in hypertensive patients
    Delles, Christian, Michelson, Georg, Harazny, Joanna, Oehmer, Sebastian, Hilgers, Karl F., Schmieder, Roland E. · 2004 · Stroke
  4. Mechanisms of cognitive impairment in cerebral small vessel disease: multimodal MRI results from the St George’s cognition and neuroimaging in stroke (SCANS) study
    Lawrence, Andrew J., Patel, Bhavini, Morris, Robin G., MacKinnon, Andrew D., Rich, Philip M., Barrick, Thomas R., Markus, Hugh S. · 2013 · PLoS ONE
  5. Modern concept of vascular cognitive impairment
    John V. Bowler · 2007 · British Medical Bulletin
  6. Development of biomarkers to chart all Alzheimer's disease stages: The royal road to cutting the therapeutic Gordian Knot
    Harald Juergen Hampel, Simone Lista, Zaven S. Khachaturian · 2012 · Alzheimer s & Dementia
  7. Clinical-neuropathologic findings in multi-infarct dementia: A report of six autopsied cases
    Hulette, C., Nochlin, D., McKeel, D., Morris, J. C., Mirra, S. S., Sumi, S. M., Heyman, A. · 1997 · Neurology
  8. Endothelial dysfunction in lacunar stroke: a systematic review
    Knottnerus, Iris L.H., Ten Cate, Hugo, Lodder, Jan, Kessels, Fons, van Oostenbrugge, Robert J. · 2009 · Cerebrovascular Diseases
  9. Brain Atrophy and Cerebral Small Vessel Disease: A Prospective Follow-Up Study
    Nitkunan, Arani, Lanfranconi, Silvia, Charlton, Rebecca A., Barrick, Thomas R., Markus, Hugh S. · 2011 · Stroke
  10. Nonhypotensive Dose of Telmisartan Attenuates Cognitive Impairment Partially Due to Peroxisome Proliferator-Activated Receptor-γ Activation in Mice With Chronic Cerebral Hypoperfusion
    Kazuo Washida, Masafumi Ihara, Keiko Nishio, Youshi Fujita, Takakuni Maki, Mahito Yamada, Jun Takahashi, Xiaofeng Wu, Takeshi Kihara, Hidefumi Ito et al. · 2010 · Stroke
  11. Oligemic Hypoperfusion Differentially Affects Tau and Amyloid-β
    Koike, Maya A., Green, Kim N., Blurton-Jones, Mathew, LaFerla, Frank M. · 2010 · The American Journal of Pathology
  12. White matter lesions and brain atrophy: more than shared risk factors? A systematic review
    Appelman, Auke P.A., Exalto, Lieza G., van der Graaf, Yolanda, Biessels, Geert Jan, Mali, Willem P.T.M., Geerlings, Mirjam I. · 2009 · Cerebrovascular Diseases
  13. Innate immunity receptor CD36 promotes cerebral amyloid angiopathy
    Laibaik Park, Joan Zhou, Ping Zhou, Rose Pistick, Sleiman El Jamal, Linda H. Younkin, Joseph P. Pierce, Andrea J. Arreguin, Josef Anrather, Steven G. Younkin et al. · 2013 · Proceedings of the National Academy of Sciences
  14. Impairments in Cognitive Function and Brain Connectivity in Severe Asymptomatic Carotid Stenosis
    Cheng, Hsien-Lin, Lin, Chun-Jen, Soong, Bing-Wen, Wang, Pei-Ning, Chang, Feng-Chi, Wu, Yu-Te, Chou, Kun-Hsien, Lin, Ching-Po, Tu, Pei-Chi, Lee, I-Hui · 2012 · Stroke
  15. Vasoactive effects of A<i>β</i>in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: Role of inflammation
    Paris, Daniel, Humphrey, James, Quadros, Amita, Patel, Nikunj, Crescentini, Robert, Crawford, Fiona, Mullan, Michael · 2003 · Neurological Research
  16. Severe carotid stenosis and impaired cerebral hemodynamics can influence cognitive deterioration
    Balestrini, Simona, Perozzi, Cecilia, Altamura, Claudia, Vernieri, Fabrizio, Luzzi, Simona, Bartolini, Marco, Provinciali, Leandro, Silvestrini, Mauro · 2013 · Neurology
  17. Cerebral Perfusion is Associated With White Matter Hyperintensities in Older Adults With Heart Failure
    Alosco, Michael L., Brickman, Adam M., Spitznagel, Mary Beth, Garcia, Sarah L., Narkhede, Atul, Griffith, Erica Y, Raz, Naftali, Cohen, Ronald, Sweet, Lawrence H., Colbert, Lisa H. et al. · 2013 · Congestive Heart Failure
  18. Leukoaraiosis and dementia in hypertensive patients.
    Hiroshi Yao, Seizo Sadoshima M. D, Setsuro Ibayashi, Yasuo Kuwabara, Y Ichiya, Masatoshi Fujishima · 1992 · Stroke
  19. Alzheimer 100 – highlights in the history of Alzheimer research
    K. A. Jellinger · 2006 · Journal of Neural Transmission
  20. Vascular Oxidative Stress: The Common Link in Hypertensive and Diabetic Vascular Disease
    Richard Alan Cohen, Xiaoyong Tong · 2010 · Journal of Cardiovascular Pharmacology
  21. Cerebral hemodynamics and cognitive impairment: Baseline data from the RECON trial
    Marshall, R.S., Festa, J.R., Cheung, Y.K., Chen, R., Pavol, M.A., Derdeyn, C.P., Clarke, W.R., Videen, T.O., Grubb, R.L., Adams, H.P. et al. · 2012 · Neurology
  22. Physical Activity Prevents Progression for Cognitive Impairment and Vascular Dementia
    Ana Verdelho, Sofia Madureira, José Manuel Ferro, Hansjörg Bäezner, Christian Blahak, Anna Poggesi, Michael G. Hennerici, Leonardo Pantoni, Franz Fazekas, Philip Scheltens et al. · 2012 · Stroke
  23. Cerebral hypoperfusion in multiple sclerosis is reversible and mediated by endothelin-1
    Miguel D’haeseleer, Roel Beelen, Yves Fierens, Melissa Cambron, Anne‐Marie Vanbinst, Christian Verborgh, Johan De Mey, Jacques De Keyser · 2013 · Proceedings of the National Academy of Sciences
  24. Rapid Disruption of Axon–Glial Integrity in Response to Mild Cerebral Hypoperfusion
    Michell M. Reimer, Jamie McQueen, Luke Searcy, Gillian A. Scullion, Barbara Zonta, Anne Desmazières, Philip R. Holland, Jessica V. Smith, Catherine M. Gliddon, Emma R. Wood et al. · 2011 · Journal of Neuroscience
  25. Relationship between cyclophilin a levels and matrix metalloproteinase 9 activity in cerebrospinal fluid of cognitively normal apolipoprotein e4 carriers and blood-brain barrier breakdown
    Halliday, Matthew R., Pomara, Nunzio, Sagare, Abhay P., Mack, Wendy J., Frangione, Blas, Zlokovic, Berislav V. · 2013 · JAMA Neurology
  26. Abnormal functional connectivity in patients with vascular cognitive impairment, no dementia: A resting-state functional magnetic resonance imaging study
    Sun, Ya-wen, Qin, Lin-di, Zhou, Yan, Xu, Qun, Qian, Li-jun, Tao, Jing, Xu, Jian-rong · 2011 · Behavioural Brain Research
  27. AD brain pathology: Vascular origins?
    Launer, Lenore J., Petrovitch, Helen, Ross, G. Webster, Markesbery, William, White, Lon R. · 2008 · Neurobiology of Aging
  28. Limitations of collateral flow after occlusion of a single cortical penetrating arteriole
    Nishimura, Nozomi, Rosidi, Nathanael L, Iadecola, Costantino, Schaffer, Chris B · 2010 · Journal of Cerebral Blood Flow &amp; Metabolism
  29. A ‘GAG’ reflex prevents repair of the damaged CNS
    Sherman, Larry S., Back, Stephen A. · 2008 · Trends in Neurosciences
  30. Decline in total cerebral blood flow is linked with increase in periventricular but not deep white matter hyperintensities
    ten Dam, V. Hester, van den Heuvel, Dominique M. J., de Craen, Anton J. M., Bollen, Edward L. E. M., Murray, Heather M., Westendorp, Rudi G. J., Blauw, Gerard J., van Buchem, Mark A. · 2007 · Radiology
  31. Chronic cerebral hypoperfusion induces MMP-2 but not MMP-9 expression in the microglia and vascular endothelium of white matter
    Ihara, Masafumi, Tomimoto, Hidekazu, Kinoshita, Makoto, Oh, Junseo, Noda, Makoto, Wakita, Hideaki, Akiguchi, Ichiro, Shibasaki, Hiroshi · 2001 · Journal of Cerebral Blood Flow &amp; Metabolism
  32. Selective reduction of blood flow to white matter during hypercapnia corresponds with leukoaraiosis
    Mandell, Daniel M., Han, Jay S., Poublanc, Julien, Crawley, Adrian P., Kassner, Andrea, Fisher, Joseph A., Mikulis, David J. · 2008 · Stroke
  33. X-linked adrenoleukodystrophy: the role of contrast-enhanced MR imaging in predicting disease progression.
    2000 · PubMed Central
  34. A systematic review of dynamic cerebral and peripheral endothelial function in lacunar stroke versus controls
    Stevenson, Susan F., Doubal, Fergus N., Shuler, Kirsten, Wardlaw, Joanna M. · 2010 · Stroke
  35. Circulating endothelial progenitor cells as a new marker of endothelial dysfunction or repair in acute stroke
    Chu, Kon, Jung, Keun-Hwa, Lee, Soon-Tae, Park, Hee-Kwon, Sinn, Dong-In, Kim, Jeong-Min, Kim, Dong-Hyun, Kim, Jin-Hee, Kim, Se-Jeong, Song, Eun-Cheol et al. · 2008 · Stroke
  36. Neurovascular coupling is impaired in slow walkers: the MOBILIZE Boston Study
    Sorond, Farzaneh A., Kiely, Dan K., Galica, Andrew, Moscufo, Nicola, Serrador, Jorge M., Iloputaife, Ike, Egorova, Svetlana, Dell'Oglio, Elisa, Meier, Dominik S., Newton, Elizabeth et al. · 2011 · Annals of Neurology
  37. Hypoperfusion of the Cerebral White Matter in Multiple Sclerosis: Possible Mechanisms and Pathophysiological Significance
    Jacques De Keyser, Christel Steen, Jop P. Mostert, Marcus Werner Koch · 2008 · Journal of Cerebral Blood Flow & Metabolism
  38. Attenuation of brain damage and cognitive impairment by direct renin inhibition in mice with chronic cerebral hypoperfusion
    Dong, Yi-Fei, Kataoka, Keiichiro, Toyama, Kensuke, Sueta, Daisuke, Koibuchi, Nobutaka, Yamamoto, Eiichiro, Yata, Kenichiro, Tomimoto, Hidekazu, Ogawa, Hisao, Kim-Mitsuyama, Shokei · 2011 · Hypertension
  39. White matter lesions defined by diffusion tensor imaging in older adults
    Back, Stephen A., Kroenke, Christopher D., Sherman, Larry S., Lawrence, Gus, Gong, Xi, Taber, Erin N., Sonnen, Joshua A., Larson, Eric B., Montine, Thomas J. · 2011 · Annals of Neurology
  40. Chronic cerebral hypoperfusion accelerates amyloid β deposition in APPSwInd transgenic mice
    Kitaguchi, Hiroshi, Tomimoto, Hidekazu, Ihara, Masafumi, Shibata, Masunari, Uemura, Kengo, Kalaria, Rajesch N., Kihara, Takeshi, Asada-Utsugi, Megumi, Kinoshita, Ayae, Takahashi, Ryosuke · 2009 · Brain Research
  41. Association between central elastic artery stiffness and cerebral perfusion in deep subcortical gray and white matter
    Tarumi, T., Shah, F., Tanaka, H., Haley, A. P. · 2011 · American Journal of Hypertension
  42. Digestion products of the PH20 hyaluronidase inhibit remyelination
    Preston, Marnie, Gong, Xi, Su, Weiping, Matsumoto, Steven G., Banine, Fatima, Winkler, Clayton, Foster, Scott, Xing, Rubing, Struve, Jaime, Dean, Justin et al. · 2013 · Annals of Neurology
  43. Prevention of Vascular Cognitive Impairment
    Dichgans, Martin, Zietemann, Vera · 2012 · Stroke
  44. Brain Microbleeds Are Associated With Ambulatory Blood Pressure Levels in a Hypertensive Population
    Léon H.G. Henskens, Robert J. van Oostenbrugge, Abraham A. Kroon, Peter W. de Leeuw, Jan Lodder · 2007 · Hypertension
  45. The Cerebral Circulation
    Marilyn J. Cipolla · 2016
  46. Genetics of cerebral amyloid angiopathy: systematic review and meta-analysis
    Kristiina Rannikmäe, Neshika Samarasekera, Nahara Anani Martínez-González, Rustam Al‐Shahi Salman, Cathie L. M. Sudlow · 2013 · Journal of Neurology Neurosurgery & Psychiatry
  47. Blood-brain barrier dysfunction in Binswanger’s disease; an immunohistochemical study
    Akiguchi, I., Tomimoto, Hidekazu, Suenaga, Toshihiko, Wakita, Hideaki, Budka, Herbert · 1998 · Acta Neuropathologica
  48. Endothelial Cell-Derived Nitric Oxide Enhances Aerobic Glycolysis in Astrocytes via HIF-1 -Mediated Target Gene Activation
    Britta Brix, J.R. Mesters, Luc Pellerin, Olaf Jöhren · 2012 · Journal of Neuroscience
  49. Astrocytes protect oligodendrocyte precursor cells via MEK/ERK and PI3K/Akt signaling
    Arai, Ken, Lo, Eng H. · 2010 · Journal of Neuroscience Research
  50. A Novel Purification Method for CNS Projection Neurons Leads to the Identification of Brain Vascular Cells as a Source of Trophic Support for Corticospinal Motor Neurons
    Jason C. Dugas, Wim J. Mandemakers, Madolyn Rogers, Adiljan Ibrahim, Richard Daneman, Ben A. Barres · 2008 · Journal of Neuroscience
  51. Blockage of CR1 prevents activation of rodent microglia
    Crehan, Helen, Hardy, John, Pocock, Jennifer · 2013 · Neurobiology of Disease
  52. Antihypertensive treatment can prevent stroke and cognitive decline
    Peter Sörös, Shawn Narain Whitehead, John David Spence, Vladimir Hachinski · 2012 · Nature Reviews Neurology
  53. Altered cerebral vasoregulation in hypertension and stroke
    Novak, V., Chowdhary, A., Farrar, B., Nagaraja, H., Braun, J., Kanard, R., Novak, P., Slivka, A. · 2003 · Neurology
  54. Visual cortical dysfunction in Alzheimer's disease evaluated with a temporally graded "stress test" during PET
    Marc J. Mentis, Barry Horwitz, C L Grady, Ge Alexander, John W. VanMeter, Jose Ma. Maisog, Pietro Pietrini, Mark B. Schapiro, С. И. Рапопорт · 1996 · American Journal of Psychiatry
  55. Cortical thinning related to periventricular and deep white matter hyperintensities
    Seo, Sang Won, Lee, Jong-Min, Im, Kiho, Park, Jun-Sung, Kim, Sook-Hui, Kim, Sung Tae, Ahn, Hyun-Jung, Chin, Juhee, Cheong, Hae-Kwan, Weiner, Michael W. et al. · 2012 · Neurobiology of Aging
  56. Altered cerebral hemodynamics in early Alzheimer disease: a pilot study using transcranial Doppler
    Claassen, Jurgen A.H.R., Diaz-Arrastia, Ramon, Martin-Cook, Kristin, Levine, Benjamin D., Zhang, Rong · 2009 · Journal of Alzheimer's Disease
  57. Occlusion of cortical ascending venules causes blood flow decreases, reversals in flow direction, and vessel dilation in upstream capillaries
    Nguyen, John, Nishimura, Nozomi, Fetcho, Robert N, Iadecola, Costantino, Schaffer, Chris B · 2011 · Journal of Cerebral Blood Flow &amp; Metabolism
  58. Huperzine a improves chronic inflammation and cognitive decline in rats with cerebral hypoperfusion
    Juan Wang, Haiyan Zhang, Xi Can Tang · 2009 · Journal of Neuroscience Research
  59. Cerebrolysin for vascular dementia
    Ning Chen, Mi Yang, Jian Guo, Muke Zhou, Cairong Zhu, Li He · 2013 · Cochrane Database of Systematic Reviews
  60. A Guide to Delineate the Logic of Neurovascular Signaling in the Brain
    David Kleinfeld, Pablo Blinder, Patrick J. Drew, Jonathan D. Driscoll, Arnaud Muller, Philbert S. Tsai, Andy Y. Shih · 2011 · Frontiers in Neuroenergetics
  61. Dynamic cerebral autoregulatory capacity is affected early in Type 2 diabetes
    Yu-Sok Kim, Rogier V. Immink, Wim J. Stok, John M. Karemaker, Niels Henry Secher, Johannes J. VAN LIESHOUT · 2008 · Clinical Science
  62. The Pathophysiology and Clinical Presentation of Cerebral Amyloid Angiopathy
    Eitan Auriel, Steven Mark Greenberg · 2012 · Current Atherosclerosis Reports
  63. Total cerebral blood flow, white matter lesions and brain atrophy: the SMART-MR study
    Appelman, Auke PA, van der Graaf, Yolanda, Vincken, Koen L, Tiehuis, Audrey M, Witkamp, Theo D, Mali, Willem PTM, Geerlings, Mirjam I, SMART Study Group · 2008 · Journal of Cerebral Blood Flow &amp; Metabolism
  64. Angiogenic and vasoprotective effects of adrenomedullin on prevention of cognitive decline after chronic cerebral hypoperfusion in mice
    Maki, Takakuni, Ihara, Masafumi, Fujita, Youshi, Nambu, Takuo, Miyashita, Kazutoshi, Yamada, Mahito, Washida, Kazuo, Nishio, Keiko, Ito, Hidefumi, Harada, Hiroshi et al. · 2011 · Stroke
  65. Detection of changed regional cerebral blood flow in mild cognitive impairment and early Alzheimer’s dementia by perfusion-weighted magnetic resonance imaging
    Luckhaus, Christian, Flüß, Michael Oliver, Wittsack, Hans-Jörg, Grass-Kapanke, Brigitte, Jänner, Michaela, Khalili-Amiri, Reza, Friedrich, Wolfgang, Supprian, Tillmann, Gaebel, Wolfgang, Mödder, Ulrich et al. · 2008 · NeuroImage
  66. Changes in background blood-brain barrier integrity between lacunar and cortical ischemic stroke subtypes
    Wardlaw, Joanna M., Farrall, Andrew, Armitage, Paul A., Carpenter, Trevor, Chappell, Francesca, Doubal, Fergus, Chowdhury, Debashish, Cvoro, Vera, Dennis, Martin S. · 2008 · Stroke
  67. Phosphodiesterase III inhibition promotes differentiation and survival of oligodendrocyte progenitors and enhances regeneration of ischemic white matter lesions in the adult mammalian brain
    Miyamoto, Nobukazu, Tanaka, Ryota, Shimura, Hideki, Watanabe, Terubumi, Mori, Hideo, Onodera, Masafumi, Mochizuki, Hideki, Hattori, Nobutaka, Urabe, Takao · 2010 · Journal of Cerebral Blood Flow &amp; Metabolism
  68. Brain Microvascular Accumulation and Distribution of the NOTCH3 Ectodomain and Granular Osmiophilic Material in CADASIL
    Yumi Yamamoto, Lucinda Craggs, Atsushi Watanabe, Trevor A. Booth, Johannes Attems, Roger W.C. Low, Arthur Ernest Oakley, Raj N. Kalaria · 2013 · Journal of Neuropathology & Experimental Neurology
  69. Association of Plasma ADMA Levels With MRI Markers of Vascular Brain Injury: Framingham Offspring Study
    Pikula, Aleksandra, Böger, Rainer H., Beiser, Alexa S., Maas, Renke, DeCarli, Charles, Schwedhelm, Edzard, Himali, Jayandra J., Schulze, Friedrich, Au, Rhoda, Kelly-Hayes, Margaret et al. · 2009 · Stroke
  70. Correlation of diffusion tensor and dynamic perfusion MR imaging metrics in normal-appearing corpus callosum: support for primary hypoperfusion in multiple sclerosis.
    Amit Manohar Saindane, M Law, Yulin Ge, Glyn Johnson, James S. Babb, Robert I. Grossman · 2007 · PubMed Central
  71. Regional cerebral blood flow and cerebrovascular reactivity in Alzheimer’s disease and vascular dementia assessed by arterial spinlabeling magnetic resonance imaging
    Gao, Yong-Zhe, Zhang, Jun-Jian, Liu, Hui, Wu, Guang-Yao, Xiong, Li, Shu, Min · 2013 · Current Neurovascular Research
  72. Vascular Care in Patients With Alzheimer Disease With Cerebrovascular Lesions Slows Progression of White Matter Lesions on MRI: The Evaluation of Vascular Care in Alzheimer’s Disease (EVA) Study
    Richard, Edo, Gouw, Alida A., Scheltens, Philip, van Gool, Willem A. · 2010 · Stroke
  73. Hereditary cerebral small vessel diseases: a review
    Federico, Antonio, Di Donato, Ilaria, Bianchi, Silvia, Di Palma, Chiara, Taglia, Ilaria, Dotti, Maria Teresa · 2012 · Journal of the Neurological Sciences
  74. Cerebral hypoperfusion induces cortical watershed microinfarcts which may further aggravate cognitive decline in Alzheimer's disease
    Judith Miklossy A · 2003 · Neurological Research
  75. The Relationship between Cortical Blood Flow and Sub-Cortical White-Matter Health across the Adult Age Span
    J. Jean Chen, Herminia Diana Rosas, David H. Salat · 2013 · PLoS ONE
  76. Involvement of oxidative stress in hypoxia-induced blood-brain barrier breakdown
    Al Ahmad, Abraham, Gassmann, Max, Ogunshola, Omolara O. · 2012 · Microvascular Research
  77. Differential effect of three cyclooxygenase inhibitors on human cerebral blood flow velocity and carbon dioxide reactivity.
    Hugh Stephen Markus, Patrick J. Vallance, Martin M. Brown · 1994 · Stroke
  78. The Blood-Brain Barrier
    Felix G. E. Dyrna, Sophie Hanske, Martin C. Krueger, Ingo Bechmann · 2013 · Journal of Neuroimmune Pharmacology
  79. Kinetics of Cerebral Amyloid Angiopathy Progression in a Transgenic Mouse Model of Alzheimer Disease
    Elissa M. Robbins, Rebecca A. Betensky, Sarah B. Domnitz, Susan M. Purcell, Mónica Garcı́a-Alloza, Charles Greenberg, George William Rebeck, Bradley T. Hyman, Steven Mark Greenberg, Matthew P. Frosch et al. · 2006 · Journal of Neuroscience
  80. Influence of Atorvastatin Treatment on <scp>l</scp> -Arginine Cerebrovascular Reactivity and Flow-Mediated Dilatation in Patients With Lacunar Infarctions
    Pretnar-Oblak, Janja, Sabovic, Miso, Sebestjen, Miran, Pogacnik, Tomaz, Zaletel, Marjan · 2006 · Stroke
  81. Edaravone attenuates white matter lesions through endothelial protection in a rat chronic hypoperfusion model
    Yuji Ueno, N. Zhang, Nobukazu Miyamoto, Ryota Tanaka, Nobutaka Hattori, Takao Urabe · 2009 · Neuroscience
  82. Genes, endothelial function and cerebral small vessel disease in man
    Markus, Hugh S. · 2008 · Experimental Physiology
  83. Specific risk factors for microbleeds and white matter hyperintensities in Alzheimer's disease
    Marije Renske Benedictus, Jeroen D.C. Goos, Maja A. A. Binnewijzend, Majon Muller, Frederik Barkhof, Philip Scheltens, Niels D. Prins, Wiesje M. van der Flier · 2013 · Neurobiology of Aging
  84. Endothelial activation in lacunar stroke subtypes
    Knottnerus, Iris L.H., Govers-Riemslag, Jose W.P., Hamulyak, Karly, Rouhl, Rob P.W., Staals, Julie, Spronk, Henri M.H., van Oerle, Rene, van Raak, Elisabeth P.M., Lodder, Jan, ten Cate, Hugo et al. · 2010 · Stroke
  85. Lessons from a Mouse Model Characterizing Features of Vascular Cognitive Impairment with White Matter Changes
    Masafumi Ihara, Hidekazu Tomimoto · 2011 · Journal of Aging Research
  86. Roles of white matter in central nervous system pathophysiologies
    Matute, Carlos, Ransom, Bruce R · 2012 · ASN Neuro
  87. Dementia associated with bilateral carotid occlusions: neuropsychological and haemodynamic course after extracranial to intracranial bypass surgery
    Tatemichi, T K, Desmond, D W, Prohovnik, I, Eidelberg, D · 1995 · Journal of Neurology, Neurosurgery &amp; Psychiatry
  88. Effects of Altered Cerebral Hemodynamics on Cognitive Function
    Randolph S. Marshall · 2012 · Journal of Alzheimer s Disease
  89. Motor function in the elderly: Evidence for the reserve hypothesis
    Elbaz, Alexis, Vicente-Vytopilova, Pavla, Tavernier, Béatrice, Sabia, Séverine, Dumurgier, Julien, Mazoyer, Bernard, Singh-Manoux, Archana, Tzourio, Christophe · 2013 · Neurology
  90. Education modifies the relation of vascular pathology to cognitive function: cognitive reserve in cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy
    Zieren, Nikola, Duering, Marco, Peters, Nils, Reyes, Sonia, Jouvent, Eric, Hervé, Dominique, Gschwendtner, Andreas, Mewald, Yvonne, Opherk, Christian, Chabriat, Hugues et al. · 2013 · Neurobiology of Aging
  91. Dissociable Effects of Alzheimer Disease and White Matter Hyperintensities on Brain Metabolism
    Thaddeus J. Haight · 2013 · JAMA Neurology
  92. Is Sticky Blood Bad for the Brain?: Hemostatic and Inflammatory Systems and Dementia in the Caerphilly Prospective Study
    Gallacher, John, Bayer, Antony, Lowe, Gordon, Fish, Mark, Pickering, Janet, Pedro, Sofia, Dunstan, Frank, White, James, Yarnell, John, Ben-Shlomo, Yoav · 2010 · Arteriosclerosis, Thrombosis, and Vascular Biology
  93. Sites of Transition Between Functional Systemic and Cerebral Arteries of Rabbits Occur at Embryological Junctional Sites
    John A. Bevan · 1979 · Science
  94. Cerebral small vessel disease in aging and <scp>A</scp>lzheimer's disease: a comparative study using <scp>MRI</scp> and <scp>SPECT</scp>
    Makedonov, I., Black, S. E., MacIntosh, B. J. · 2013 · European Journal of Neurology
  95. Genome-wide association study of vascular dementia
    Schrijvers, Elisabeth M.C., Schürmann, Britta, Koudstaal, Peter J., van den Bussche, Hendrik, Van Duijn, Cornelia M., Hentschel, Frank, Heun, Reinhard, Hofman, Albert, Jessen, Frank, Kölsch, Heike et al. · 2012 · Stroke
  96. Angiogenic T-Cells and Putative Endothelial Progenitor Cells in Hypertension-Related Cerebral Small Vessel Disease
    Rob P.W. Rouhl, Annelien E.C.S. Mertens, Robert J. van Oostenbrugge, Jan G.M.C. Damoiseaux, Lucienne Debrus-Palmans, Léon H.G. Henskens, Abraham A. Kroon, Peter W. de Leeuw, Jan Lodder, Jan Willem Cohen Tervaert · 2011 · Stroke
  97. Reduced circulating angiogenic cells in Alzheimer disease
    Lee, S-T, Chu, K., Jung, K-H, Park, H-K, Kim, D-H, Bahn, J-J, Kim, J-H, Oh, M-J, Lee, S. K., Kim, M. et al. · 2009 · Neurology
  98. The Neuropathology of Vascular Disease in the Medical Research Council Cognitive Function and Ageing Study (MRC CFAS)
    Kathryn Richardson, Blossom C. M. Stephan, Paul G. Ince, Carol Brayne, Fiona E. Matthews · 2012 · Current Alzheimer Research
  99. White matter lesions and lacunar infarcts are independently and differently associated with brain atrophy: the SMART-MR study
    Appelman, Auke P.A., Vincken, Koen L., van der Graaf, Yolanda, Vlek, Anne L.M., Witkamp, Theo D., Mali, Willem P.T.M., Geerlings, Mirjam I. · 2010 · Cerebrovascular Diseases
  100. Oligodendroglial cell death with DNA fragmentation in the white matter under chronic cerebral hypoperfusion: comparison between normotensive and spontaneously hypertensive rats
    Makoto Masumura, Ryuji Hata, Yasuo Nagai, Tohru Sawada · 2001 · Neuroscience Research
  101. Alzheimer's disease and other neurological disorders
    Victor W. Henderson · 2007 · Climacteric
  102. Increased blood-brain barrier permeability in white matter lesions of Binswanger’s disease evaluated by contrast-enhanced MRI
    Hanyu, Haruo, Asano, Tetsuichi, Tanaka, Yuriko, Iwamoto, Toshihiko, Takasaki, Masaru, Abe, Kimihiko · 2002 · Dementia and Geriatric Cognitive Disorders
  103. Circulating endothelial progenitor cells and age-related white matter changes
    Jickling, Glen, Salam, Abdul, Mohammad, Askar, Hussain, Muhammad S., Scozzafava, James, Nasser, Abdul Majeed, Jeerakathil, Thomas, Shuaib, Ashfaq, Camicioli, Richard · 2009 · Stroke
  104. Changes of brachial flow-mediated vasodilation in different ischemic stroke subtypes
    Chen, P. L., Wang, P. Y., Sheu, W. H., Chen, Y. T., Ho, Y. P., Hu, H. H., Hsu, H. Y. · 2006 · Neurology
  105. Distinctive RNA Expression Profiles in Blood Associated With White Matter Hyperintensities in Brain
    Huichun Xu, Boryana S. Stamova, Glen C. Jickling, Yingfang Tian, Xinhua Zhan, Bradley P. Ander, Dazhi Liu, Renée J. Turner, Jonathan M. Rosand, Larry B. Goldstein et al. · 2010 · Stroke
  106. APOE ε4, Alzheimer’s disease pathology, cerebrovascular disease, and cognitive change over the years prior to death.
    Lei Yu, Patricia A. Boyle, Julie A. Schneider, Eisuke Segawa, Robert S. Wilson, Sue E. Leurgans, David Alan Bennett · 2013 · Psychology and Aging
  107. Perivascular deposits of serum proteins in cerebral cortex in vascular dementia
    Alafuzoff, I., Adolfsson, R., Grundke-Iqbal, I., Winblad, B. · 1985 · Acta Neuropathologica
  108. Gypenoside attenuates white matter lesions induced by chronic cerebral hypoperfusion in rats
    Guanglin Zhang, Zhenwei Zhao, Li Gao, Jianping Deng, Benhan Wang, Dun-Quan Xu, Bolin Liu, Youzhi Qu, Yu Jia, Jian Li et al. · 2011 · Pharmacology Biochemistry and Behavior
  109. Is endothelial dysfunction of cerebral small vessel responsible for white matter lesions after chronic cerebral hypoperfusion in rats?
    Huang, Yonghua, Zhang, Weiwei, Lin, Lang, Feng, Jun, Chen, Fei, Wei, Wei, Zhao, Xiuxin, Guo, Wenhua, Li, Juan, Yin, Weimin et al. · 2010 · Journal of the Neurological Sciences
  110. Multiple pathologies are common in Alzheimer patients in clinical trials
    Wang, B. W., Lu, E., Mackenzie, I. R. A., Assaly, M., Jacova, C., Lee, P. E., Beattie, B. L., Hsiung, G. Y. R. · 2012 · Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques
  111. β-Amyloid Aggregation in Human Brains With Cerebrovascular Lesions
    Aho, Leena, Jolkkonen, Jukka, Alafuzoff, Irina · 2006 · Stroke
  112. Regional Cerebral Blood Flow Abnormalities in Nondemented Patients With Memory Impairment
    Makoto Tanaka, Hidenao Fukuyama, Hiroshi Yamauchi, Minoru Narita, Hidehiko Nabatame, Masayuki Yokode, Naoki Fujimoto, Toru Kita, Motonobu Murakami · 2002 · Journal of Neuroimaging
  113. Small concomitant cerebrovascular lesions are not important for cognitive decline in severe Alzheimer disease
    Jellinger, Kurt A. · 2001 · Archives of Neurology
  114. C-reactive protein expression in a rodent model of chronic cerebral hypoperfusion
    Wafa M. Juma, Arman Lira, Ali Marzuk, Zaynab Marzuk, Antoine M. Hakim, Charlie S. Thompson · 2011 · Brain Research
  115. Genetics of subcortical vascular dementia
    Schmidt, Helena, Freudenberger, Paul, Seiler, Stephan, Schmidt, Reinhold · 2012 · Experimental Gerontology
  116. Cerebral microbleeds are related to subjective cognitive failures: the RUN DMC study
    van Norden, Anouk G.W., van Uden, Inge W.M., de Laat, Karlijn F., Gons, Rob A.R., Kessels, Roy P.C., van Dijk, Ewoud J., de Leeuw, Frank-Erik · 2013 · Neurobiology of Aging
  117. Hypoperfusion predicts lesion progression in cerebral X-linked adrenoleukodystrophy
    Musolino, P. L., Rapalino, O., Caruso, P., Caviness, V. S., Eichler, F. S. · 2012 · Brain
  118. Evaluation of asymmetric dimethylarginine and homocysteine in microangiopathy-related cerebral damage
    Notsu, Y., Nabika, T., Bokura, H., Suyama, Y., Kobayashi, S., Yamaguchi, S., Masuda, J. · 2009 · American Journal of Hypertension
  119. Mucosal Tolerization to E-Selectin Protects against Memory Dysfunction and White Matter Damage in a Vascular Cognitive Impairment Model
    Hideaki Wakita, Christl A. Ruetzler, Kachikwu Illoh, Yong Chen, Asako Takanohashi, Maria Spatz, John M. Hallenbeck · 2007 · Journal of Cerebral Blood Flow & Metabolism
  120. Subacute Ischemic Stroke Is Associated With Focal 11 C PiB Positron Emission Tomography Retention But Not With Global Neocortical Aβ Deposition
    John V Ly, Christopher Cleon Rowe, Victor L. Villemagne, Jorge A. Zavala, Henry Ma, Ramesh Sahathevan, Graeme Joseph O'Keefe, Sylvia Jie Gong, Rico Gunawan, Leonid P. Churilov et al. · 2012 · Stroke
  121. Pre-clinical models of human cerebral small vessel disease: Utility for clinical application
    Atticus H. Hainsworth, John F. Brittain, Halima Khatun · 2012 · Journal of the Neurological Sciences
  122. Cerebrovascular degradation of TRKB by MMP9 in the diabetic brain
    Navaratna, Deepti, Fan, Xiang, Leung, Wendy, Lok, Josephine, Guo, Shuzhen, Xing, Changhong, Wang, Xiaoying, Lo, Eng H. · 2013 · Journal of Clinical Investigation
  123. Plasma levels of asymmetric dimethylarginine in cerebral autosomal dominant arteriopathy with subcortical infarct and leukoencephalopathy
    Rufa, Alessandra, Blardi, Patrizia, De Lalla, Arianna, Cevenini, Gabriele, De Stefano, Nicola, Zicari, Enza, Auteri, Alberto, Federico, Antonio, Dotti, Maria Teresa · 2008 · Cerebrovascular Diseases
  124. Human aging and CD31 + T-cell number, migration, apoptotic susceptibility, and telomere length
    Erich Joseph Kushner, Brian Raymond Weil, Owen J. MacEneaney, R. Garrett Morgan, Michael L. Mestek, Gary P. Van Guilder, Kyle J. Diehl, Brian L. Stauffer, Christopher A. DeSouza · 2010 · Journal of Applied Physiology
  125. Higher cerebral function and hemispheric blood flow during awake carotid artery balloon test occlusions
    Marshall, R S, Lazar, R M, Mohr, J P, Pile-Spellman, J, Hacein-Bey, L, Duong, D H, Joshi, S, Chen, X, Levin, B., Young, W L · 1999 · Journal of Neurology, Neurosurgery &amp; Psychiatry
  126. Prevalence of cerebral vascular amyloid-β deposition and stroke in an aging Australian population: a postmortem study
    Frank Louis Mastaglia, Michelle L. Byrnes, Russell D. Johnsen, Byron A. Kakulas · 2003 · Journal of Clinical Neuroscience
  127. Stroke and Alzheimer Disease
    Vladimir Hachinski · 2011 · Archives of Neurology
  128. Correlation of NO Metabolites and 8-Iso-Prostaglandin F 2a With Periventricular Hyperintensity Severity
    Hiroshi Shibata, Toru Nabika, Hidehiko Moriyama, Junichi Masuda, Shotai Kobayashi · 2004 · Arteriosclerosis Thrombosis and Vascular Biology
  129. Low cerebrospinal fluid sulfatide predicts progression of white matter lesions: The LADIS study
    Jonsson, Michael, Zetterberg, Henrik, Rolstad, Sindre, Edman, Ake, Gouw, Alida A., Bjerke, Maria, Lind, Karin, Blennow, Kaj, Pantoni, Leonardo, Inzitari, Domenico et al. · 2012 · Dementia and Geriatric Cognitive Disorders
  130. Ramipril protects from free radical induced white matter damage in chronic hypoperfusion in the rat
    Joong‐Seok Kim, Injin Yun, Young Bin Choi, Kwang‐Soo Lee, Yeong-In Kim · 2007 · Journal of Clinical Neuroscience
  131. Special characteristics of the cerebral circulation.
    François M. Abboud · 1981 · PubMed
  132. Genetic Animal Models of Cerebral Vasculopathies
    Jeong Hyun Lee, Brian J. Bacskai, Cenk Ayata · 2011 · Progress in molecular biology and translational science
  133. Histopathological stainings and definitions of vascular disruptions in the elderly brain
    Jacques L. De Reuck · 2012 · Experimental Gerontology
  134. CD31+ T cells, endothelial function and cardiovascular risk
    Weil, Brian R., Kushner, Erich J., Diehl, Kyle J., Greiner, Jared J., Stauffer, Brian L., DeSouza, Christopher A. · 2011 · Heart, Lung and Circulation
  135. Alzheimer Disease: Caused by Primary Deficiency of the Cerebral Blood Flow
    E. Niedermeyer · 2006 · Clinical EEG and Neuroscience
  136. Complex genetic susceptibility to vascular dementia and an evidence for its underlying genetic factors associated with memory and associative learning
    Lee, Chaeyoung, Kim, Younyoung · 2013 · Gene
  137. Topological dynamics in spike-timing dependent plastic model neural networks
    David B. Stone, Claudia D. Tesche · 2013 · Frontiers in Neural Circuits
  138. Dementia.
    Rob Butler, Raghavakurup Radhakrishnan · 2012 · PubMed Central
  139. Immunoglobulin G induces microglial superoxide production
    Yoshida, Toshihiko, Tanaka, Makoto, Okamoto, Koichi · 2002 · Neurological Research
  140. Adrenoleukodystrophy: cortical hypoperfusion demonstrated with 99mTc-HMPAO SPECT
    Al Suhaili, Abdul Rahim, Hertecant, Jozef, Sztriha, László · 1994 · Journal of Child Neurology
  141. Cerebral blood flow on ECD SPECT in a patient with adult onset Alexander disease
    Ito, Kimiteru, Takeuchi, Sousuke, Hasuo, Kanehiro, Morooka, Miyako, Kubota, Kazuo, Matsuda, Hiroshi · 2009 · Clinical Nuclear Medicine