The DOI matches its Crossref record; 73 of the 73 references it cites were found in a registry or an index.
The Emerging Field of Neuroepigenetics
Open accessAbstract
Over the past 25 years, the broad field of epigenetics and, over the past decade in particular, the emerging field of neuroepigenetics have begun to have tremendous impact in the areas of learned behavior, neurotoxicology, CNS development, cognition, addiction, and psychopathology. However, epigenetics is such a new field that in most of these areas the impact is more in the category of fascinating implications as opposed to established facts. In this brief commentary, I will attempt to address and delineate some of the open questions and areas of opportunity that discoveries in epigenetics are providing to the discipline of neuroscience.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The source backs part of the claim, not all of it — or backs it for a different population, condition or comparison.
In the citing paper
“Epigenetic regulation mediates direct epigenetic effects or gene-by-environment interactions and can lead to complex diseases.33,34”
From Epigenetic regulation in major depression and other stress-related disorders: molecular mechanisms, clinical relevance and therapeutic potential (2023) · cites this paper as [33]
Experimental — accuracy not yet measured
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Jenuwein, T., & Allis, C. D. (2001) · Science · doi:10.1126/science.1063127 · Cited by 9,756
The language of covalent histone modifications
Strahl, B. D., & Allis, C. D. (2000) · Nature · doi:10.1038/47412 · Cited by 8,679
DNA methylation patterns and epigenetic memory
Bird, A. (2002) · Genes & Development · doi:10.1101/gad.947102 · Cited by 7,124
Epigenetic programming by maternal behavior
Weaver, I. C. G., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004) · Nature Neuroscience · doi:10.1038/nn1276 · Cited by 6,177
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
Tahiliani, M., Koh, K. P., Shen, Y., Pastor, W. A., Bandukwala, H., Brudno, Y., Agarwal, S., Iyer, L. M., Liu, D. R., Aravind, L., et al. (2009) · Science · doi:10.1126/science.1170116 · Cited by 5,836
Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine
Ito, S., Shen, L., Dai, Q., Wu, S. C., Collins, L. B., Swenberg, J. A., He, C., & Zhang, Y. (2011) · Science · doi:10.1126/science.1210597 · Cited by 3,451
The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain
Kriaucionis, S., & Heintz, N. (2009) · Science · doi:10.1126/science.1169786 · Cited by 2,700
Ito, S., D’Alessio, A. C., Taranova, O., Hong, K., Sowers, L. C., & Zhang, Y. (2010) · Nature · doi:10.1038/nature09303 · Cited by 2,628
Combinatorial patterns of histone acetylations and methylations in the human genome
Wang, Z., Zang, C., Rosenfeld, J. A., Schones, D. E., Barski, A., Cuddapah, S., Cui, K., Roh, T.-Y., Peng, W., Zhang, M. Q., et al. (2008) · Nature Genetics · doi:10.1038/ng.154 · Cited by 2,331
Global epigenomic reconfiguration during mammalian brain development
Lister, R., Mukamel, E. A., Nery, J. R., Urich, M., Puddifoot, C. A., Johnson, N. D., Lucero, J., Huang, Y., Dwork, A. J., Schultz, M. D., et al. (2013) · Science · doi:10.1126/science.1237905 · Cited by 1,830
Flagged first, then by citations
Cited by
Sorted by citations
Items 301–324 of 324
Moormann, E., & Hens, K. (2024) · Bristol University Press eBooks · doi:10.56687/9781529225440-002
CRISPR for gene editing in neuroscience and neurological disease
Ostick, J. L. (2017) · Advances in Clinical Neuroscience & Rehabilitation · doi:10.47795/defx7218
Lux, V. (2024) · SpringerBriefs in psychology · doi:10.1007/978-3-031-55229-8_2
Lux, V. (2024) · SpringerBriefs in psychology · doi:10.1007/978-3-031-55229-8_4
Epigenetics Crosslink with Nutrition and Brain Function
Abdelhameed, A. M., & Dakhlallah, D. A. (2024) · Springer eBooks · doi:10.1007/978-981-99-7557-0_1
Is Ecological Neuroscience Possible?
Camarena, J. (2024) · Interdisciplinary evolution research · doi:10.1007/978-3-031-70847-3_10
Thorn within: the environment in personal identity
Vulliermet, F. (2025) · Epigenetics Communications · doi:10.1186/s43682-025-00036-0
Ji, M. T., Przybyl, K. J., Harter, A. M., Nemesh, M., Jenz, S. T., Yamazaki, A., Kim, C., Mulligan, M. K., Chen, H., & Redei, E. E. (2025) · Genes Brain & Behavior · doi:10.1111/gbb.70027
Epigenetic effects of Nosustrophine in Alzheimer’s disease
Martínez-Iglesias, O. A., Naidoo, V., Carrera, I., Corzo, L., & Cacabelos, R. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-18722-3.00024-4
Stephens, K., Zhou, W., Renfro, Z. T., Ji, Z., Ji, H., Guan, Y., & Taverna, S. D. (2021) · Figshare · doi:10.6084/m9.figshare.16456515
Pysanko, V. (2025) · SSRN Electronic Journal · doi:10.2139/ssrn.5389421
Methylation and merriment: an exploration of epigenetic mechanisms underlying play behaviour
Malka, R. J., Arranz, M., & Baselga-Carretero, I. (2026) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1002/brv.70142
Penner-Goeke, S., & Binder, E. B. (2026) · Neuron · doi:10.1016/j.neuron.2026.02.014 · Cited by 3
Synthèses d’inhibiteurs de HDAC et leurs tests biologiques (Cytotoxicité, HDAC inhibition)
Ozdarska, K. (2020) · theses.fr (ABES) · doi:10.70675/9f872011z7544z4b35z8e5ezcf4812094c2e
Larson, D. O., Sarto‐Jackson, I., & Fischer, B. (2026) · Biological Theory · doi:10.1007/s13752-026-00536-9
Liu, D., Tao, K., Wang, Y., Sun, Y., & Wang, S. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-06035-z · Cited by 1
Epigenetic Pathways to Giftedness: Bridging Biology and Talent Development
Akdeniz, H. (2026) · Gifted Child Quarterly · doi:10.1177/00169862261464932
Epigenetic and Transcriptomic Regulations in Brain Disorders
Pal, A., & Rathored, J. (2026) · Royal Society of Chemistry eBooks · doi:10.1039/9781837071395-00203
Hancock, J., & Becht-Buss, D. (2026) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2026.1862960
Impact of post-translational modifications in Alzheimer’s disease: An overview
Venkataramaiah, C. (2026) · Current Proteomics · doi:10.1016/j.curpro.2026.100189
Sleep-dependent DNA methylation remodeling in basolateral amygdala fear engrams
Chen, X., Ruan, F., Rodriguez, A. M., Pan, R., Wang, R., Jin, M., 周连艳, Yi, K., Liu, H., Zhou, W., et al. (2026) · Cell Reports · doi:10.1016/j.celrep.2026.118190
Neuroscience, Resilience, and the Embodiment of “Mental” Disorder
Garland, E. L., & Thomas, E. A. (2015) · Springer eBooks · doi:10.1007/978-3-319-17774-8_6
Metadata
- Authors
- Sweatt, J. D.
- Affiliations
- University of Alabama at Birmingham (US)
- Corresponding author
- Sweatt, J. David
- ORCID
- Sweatt, J. David
- Venue
- Neuron
- Publisher
- Elsevier BV
- Published
- 2013-10
- Volume
- 80
- Issue
- 3
- Pages
- 624-632
- ISSN
- 0896-6273 (ISSN-L)
- PMC
- PMC3878295
- OpenAlex
- W2162596587
- Cited by
- 324
- References
- 73
- Citations by year
- 2026: 15 · 2025: 9 · 2024: 18 · 2023: 20 · 2022: 13 · 2021: 15 · 2020: 18 · 2019: 24 · 2018: 32 · 2017: 49 · 2016: 42 · 2015: 42 · 2014: 26 · 2013: 1
- FWCI
- 3.48
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Neuron (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institute on Aging (R01AG031722)
- National Institute of Mental Health (R01MH091122, R01MH057014)
- National Institute of Nursing Research (R01NR012686)
- National Institute of Neurological Disorders and Stroke (P30NS057098)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Epigenetics and DNA Methylation
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- neuroepigenetics, epigenetics, learned behavior, neurotoxicology, central nervous system development, cognition, addiction, psychopathology
- MeSH terms
- Animals, Humans, Neurosciences, Epigenesis, Genetic, History, 20th Century, History, 21st Century, Epigenomics
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review